Page last updated: 2024-11-03

propofol and Hemorrhage, Uterine

propofol has been researched along with Hemorrhage, Uterine in 4 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"In a prospective randomised study 52 ASA I patients scheduled for ambulatory pregnancy termination were premedicated with lorazepam and received alfentanil prior to anaesthesia induction with propofol (group P, n = 26) or with sevoflurane 8% (group S, n = 26) using the single breath vital capacity technique."5.08Comparison of sevoflurane and propofol for ambulatory anaesthesia in gynaecological surgery. ( Feiss, P; Lahrimi, A; Nathan, N; Peyclit, A, 1998)
"Operating conditions, recovery and postoperative nausea and vomiting (PONV) were assessed."2.69Comparison of sevoflurane-nitrous oxide and propofol-alfentanil-nitrous oxide anaesthesia for minor gynaecological surgery. ( Korttila, K; Nelskylä, K; Yli-Hankala, A, 1999)
"Although peripartum cardiac arrest is rare, the prognosis of the event may be worse than in nonpregnant patients because the events is often associated with pulmonary or amniotic embolisms."1.31[A case of cardiac arrest at induction of anesthesia for postpartum hysterectomy]. ( Amano, K; Hashiba, M; Hoka, S; Okamoto, H; Okutomi, T; Saito, K, 2002)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tas, A1
Mıstanoglu, V1
Darcın, S1
Kececioglu, M1
Hashiba, M1
Okutomi, T1
Saito, K1
Amano, K1
Okamoto, H1
Hoka, S1
Nathan, N1
Peyclit, A1
Lahrimi, A1
Feiss, P1
Nelskylä, K1
Korttila, K1
Yli-Hankala, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sevoflurane as an Anesthetic During Dilation and Evacuation Procedures: Does it Increase Blood Loss and Interventions for Blood Loss and Why Do Anesthesiologists Choose to Use It?[NCT01048658]Phase 4160 participants (Actual)Interventional2009-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Experiencing Side Effects (Nausea, Dizziness)

(NCT01048658)
Timeframe: Post-procedure, within 30 minutes

InterventionParticipants (Count of Participants)
Sevoflurane13
No Sevoflurane11

Number of Participants Needing Intervention to Treat Blood Loss (a Composite of Use of Uterotonics, Re-aspiration, and Bimanual Massage)

Provider report for need to intervene due to blood loss (yes/no) (NCT01048658)
Timeframe: At time of uterine evacuation and immediately post-operatively, an average of 7.1 minutes

InterventionParticipants (Count of Participants)
Sevoflurane20
No Sevoflurane13

Number of Participants With Estimated Blood Loss Greater Than 300 mL (Yes/no)

Procedural blood loss greater than 300 mL. Blood loss was measured in a standardized fashion (amniotic fluid was discarded, blood was separated from tissue, and all gauze surgical drapes weighed). (NCT01048658)
Timeframe: At time of uterine evacuation, an average of 7.1 minutes

InterventionParticipants (Count of Participants)
Sevoflurane12
No Sevoflurane6

Procedure Time: T-test (Time of Speculum Placement to Time Speculum Removed)

Length of procedure from time of speculum placement to time of speculum removal, in minutes. (NCT01048658)
Timeframe: Time of speculum place to time of speculum removal, an average of 7.1 minutes

Interventionminutes (Mean)
Sevoflurane7.0
No Sevoflurane7.3

Patient and Provider Satisfaction With Anesthesia

Scores reported on 10-cm Visual Analog Scale (VAS anchors: 0= not satisfied at all, 10= completely satisfied) . Reported as mean +/- standard deviation. Subjects and providers were blinded to anesthesia method. Subjects and providers completed post-operative questionnaire within 30 minutes of procedure completion. (NCT01048658)
Timeframe: Post-procedure, within 30 minutes

,
Interventioncm (Mean)
Provider SatisfactionPatient Satisfaction
No Sevoflurane9.38.2
Sevoflurane9.48.4

Trials

3 trials available for propofol and Hemorrhage, Uterine

ArticleYear
Tramadol versus fentanyl during propofol-based deep sedation for uterine dilatation and curettage: a prospective study.
    The journal of obstetrics and gynaecology research, 2014, Volume: 40, Issue:3

    Topics: Adult; Analgesics, Opioid; Deep Sedation; Dilatation and Curettage; Double-Blind Method; Female; Fen

2014
Comparison of sevoflurane and propofol for ambulatory anaesthesia in gynaecological surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:12

    Topics: Abortion, Induced; Activities of Daily Living; Adult; Ambulatory Surgical Procedures; Anesthesia, Ge

1998
Comparison of sevoflurane-nitrous oxide and propofol-alfentanil-nitrous oxide anaesthesia for minor gynaecological surgery.
    British journal of anaesthesia, 1999, Volume: 83, Issue:4

    Topics: Adult; Alfentanil; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Inhalation; Anest

1999

Other Studies

1 other study available for propofol and Hemorrhage, Uterine

ArticleYear
[A case of cardiac arrest at induction of anesthesia for postpartum hysterectomy].
    Masui. The Japanese journal of anesthesiology, 2002, Volume: 51, Issue:12

    Topics: Adult; Anesthesia, General; Cesarean Section; Female; Heart Arrest; Humans; Hysterectomy; Intraopera

2002