propofol has been researched along with Hemorrhage, Subarachnoid in 31 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Excerpt | Relevance | Reference |
---|---|---|
"Sixty adult patients with good grade subarachnoid hemorrhage undergoing diagnostic cerebral angiography were prospectively randomized to receive either propofol (n = 30) or dexmedetomidine (n = 30) following ethics committee approval and informed consent." | 9.20 | A comparative study of dexmedetomidine and propofol as sole sedative agents for patients with aneurysmal subarachnoid hemorrhage undergoing diagnostic cerebral angiography. ( Jena, S; Mittal, M; Reddy, M; Sriganesh, K; Umamaheswara Rao, GS, 2015) |
"Agitation is common in subarachnoid hemorrhage (SAH), and sedation with midazolam, propofol and dexmedetomidine is essential in agitation management." | 8.12 | Cerebrospinal fluid metabolic profiling reveals divergent modulation of pentose phosphate pathway by midazolam, propofol and dexmedetomidine in patients with subarachnoid hemorrhage: a cohort study. ( A, JY; Ding, XS; Ge, WH; Li, YC; Liu, T; Na, SJ; Sun, RB; Wang, R, 2022) |
"Propofol significantly reduces neurological dysfunction, BBB permeability, brain edema, inflammation, and oxidative stress, all of which were reversed by LY294002." | 7.91 | Propofol Reduces Inflammatory Brain Injury after Subarachnoid Hemorrhage: Involvement of PI3K/Akt Pathway. ( Chen, Q; Shi, SS; Tu, XK; Zhang, HB, 2019) |
" She had taken prednisolone (3 mg x day(-1)) and methotrexate (MTX) (10 mg x week(-1)) for rheumatoid arthritis for the last 10 years." | 7.78 | [Anesthetic management of a patient with thrombocytopenia induced by methotrexate undergoing emergent clipping surgery]. ( Doi, A; Kurita, S; Morishima, K; Nagata, N; Nakanishi, M; Nakatani, K; Nishi, Y; Yagi, M; Yamama, Y, 2012) |
"Propofol infusion syndrome (PRIS) is a rare but frequently fatal condition." | 7.77 | Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage. ( Kumar, MA; Levine, JM; Pisapia, JM; Wendell, LC; Zager, EL, 2011) |
" We used digital subtraction angiography to compare the effects of propofol and sevoflurane on the luminal diameter of cerebral vessels and on cerebral transit time in patients with aneurysmal subarachnoid hemorrhage (aSAH)." | 5.69 | Comparison of Effects of Propofol and Sevoflurane on the Cerebral Vasculature Assessed by Digital Subtraction Angiographic Parameters in Patients Treated for Ruptured Cerebral Aneurysm: A Preliminary Study. ( Ahuja, CK; Bhagat, H; Chauhan, R; Jain, C; Jangra, K; Joys, S; Kaloria, N; Luthra, A; Mahajan, S; Panda, NB; Regmi, S; Singh, N; Soni, SL; Tripathi, M, 2023) |
"Sprague-Dawley rats underwent subarachnoid hemorrhage (SAH) by endovascular perforation then received treatment with propofol (10 or 50 mg/kg) or vehicle after 2 and 12 h of SAH." | 5.42 | Propofol Attenuates Early Brain Injury After Subarachnoid Hemorrhage in Rats. ( Chen, Y; Liang, RS; Shi, SS; Tu, XK; Wang, CH; Yang, WZ; Zhang, HB, 2015) |
"The seizure was suppressed by the administration of thiamylal." | 5.31 | [Generalized tonic-clonic seizure induced by propofol in a patient with epilepsy]. ( Hazama, K; Iwasaki, F; Mimura, M; Namiki, A; Sato, Y; Yamazaki, Y, 2001) |
"Sixty adult patients with good grade subarachnoid hemorrhage undergoing diagnostic cerebral angiography were prospectively randomized to receive either propofol (n = 30) or dexmedetomidine (n = 30) following ethics committee approval and informed consent." | 5.20 | A comparative study of dexmedetomidine and propofol as sole sedative agents for patients with aneurysmal subarachnoid hemorrhage undergoing diagnostic cerebral angiography. ( Jena, S; Mittal, M; Reddy, M; Sriganesh, K; Umamaheswara Rao, GS, 2015) |
"Agitation is common in subarachnoid hemorrhage (SAH), and sedation with midazolam, propofol and dexmedetomidine is essential in agitation management." | 4.12 | Cerebrospinal fluid metabolic profiling reveals divergent modulation of pentose phosphate pathway by midazolam, propofol and dexmedetomidine in patients with subarachnoid hemorrhage: a cohort study. ( A, JY; Ding, XS; Ge, WH; Li, YC; Liu, T; Na, SJ; Sun, RB; Wang, R, 2022) |
"Propofol significantly reduces neurological dysfunction, BBB permeability, brain edema, inflammation, and oxidative stress, all of which were reversed by LY294002." | 3.91 | Propofol Reduces Inflammatory Brain Injury after Subarachnoid Hemorrhage: Involvement of PI3K/Akt Pathway. ( Chen, Q; Shi, SS; Tu, XK; Zhang, HB, 2019) |
" Patients with aneurysmal subarachnoid hemorrhage are often sedated, and GABAergic sedation, such as midazolam and propofol, is commonly used." | 3.83 | Use of GABAergic sedatives after subarachnoid hemorrhage is associated with worse outcome-preliminary findings. ( Beynon, C; Hertle, DN; Neumann, JO; Sakowitz, OW; Sánchez-Porras, R; Santos, E; Unterberg, AW, 2016) |
" She had taken prednisolone (3 mg x day(-1)) and methotrexate (MTX) (10 mg x week(-1)) for rheumatoid arthritis for the last 10 years." | 3.78 | [Anesthetic management of a patient with thrombocytopenia induced by methotrexate undergoing emergent clipping surgery]. ( Doi, A; Kurita, S; Morishima, K; Nagata, N; Nakanishi, M; Nakatani, K; Nishi, Y; Yagi, M; Yamama, Y, 2012) |
"Propofol infusion syndrome (PRIS) is a rare but frequently fatal condition." | 3.77 | Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage. ( Kumar, MA; Levine, JM; Pisapia, JM; Wendell, LC; Zager, EL, 2011) |
" The purpose of the present study was to explore whether changes in plasma ET and calcitonin gene-related peptide (CGRP) concentrations were altered during propofol anesthesia in patients undergoing clipping of an intracranial aneurysm." | 3.75 | Changes of endothelin and calcitonin gene-related peptide concentrations in plasma during propofol anesthesia. ( Ji, N; Luo, F; Wang, T; Zhang, S; Zhao, J, 2009) |
"To evaluate the effects of the neurological "wake-up test" (NWT), defined as interruption of continuous propofol sedation and evaluation of the patient's level of consciousness, on intracranial pressure (ICP) and cerebral perfusion pressure (CPP) in patients with severe subarachnoid hemorrhage (SAH) or traumatic brain injury (TBI)." | 3.75 | Effects of the neurological wake-up test on intracranial pressure and cerebral perfusion pressure in brain-injured patients. ( Enblad, P; Marklund, N; Skoglund, K, 2009) |
"Isoflurane is a volatile anesthetic that has a vasodilating effect on cerebral vessels producing a cerebral blood flow increase." | 2.77 | Inhalation versus endovenous sedation in subarachnoid hemorrhage patients: effects on regional cerebral blood flow. ( Aletti, G; Citerio, G; Giussani, C; Iacca, C; Molinari, AF; Pesenti, A; Villa, F, 2012) |
"The incidence of cardiac dysrhythmias was similar in the study groups." | 2.70 | QT interval and QT dispersion during the induction of anaesthesia in patients with subarachnoid haemorrhage: a comparison of thiopental and propofol. ( Kyttä, JV; Randell, TT; Tanskanen, PE, 2002) |
"Cerebral vasospasm is the most important cause of morbidity after an aneurysm clipping in the early postoperative period." | 1.48 | The effect of anesthetic agents on cerebral vasospasms after subarachnoid hemorrhage: A retrospective study. ( Baik, HJ; Chae, JS; Kim, DY; Lee, JW; Seo, EK; Woo, JH; Yang, NR, 2018) |
"Patients with aneurysmal subarachnoid hemorrhage (aSAH) are common in intensive care units (ICU)." | 1.42 | The effect of tracheotomy on drug consumption in patients with acute aneurysmal subarachnoid hemorrhage: an observational study. ( Kongsgaard, U; Narum, J; Rosseland, LA; Sorteberg, A; Sorteberg, W; Stubhaug, A, 2015) |
"Sprague-Dawley rats underwent subarachnoid hemorrhage (SAH) by endovascular perforation then received treatment with propofol (10 or 50 mg/kg) or vehicle after 2 and 12 h of SAH." | 1.42 | Propofol Attenuates Early Brain Injury After Subarachnoid Hemorrhage in Rats. ( Chen, Y; Liang, RS; Shi, SS; Tu, XK; Wang, CH; Yang, WZ; Zhang, HB, 2015) |
"Thiopental was added for treatment of intracranial hypertension." | 1.38 | Frequency of non-convulsive seizures and non-convulsive status epilepticus in subarachnoid hemorrhage patients in need of controlled ventilation and sedation. ( Lindgren, C; Naredi, S; Nordh, E; Olivecrona, M, 2012) |
"In patients with subarachnoid hemorrhage (SAH) a disturbance of cerebral autoregulation has been reported and it correlated with the severity of the bleeding in these studies." | 1.33 | Dynamic cerebral autoregulation in patients with ruptured and unruptured aneurysms after induction of general anesthesia. ( Christmann, A; Engelhardt, M; Harders, A; Möller, F; Schmieder, K; Scholz, M; Schregel, W, 2006) |
"The seizure was suppressed by the administration of thiamylal." | 1.31 | [Generalized tonic-clonic seizure induced by propofol in a patient with epilepsy]. ( Hazama, K; Iwasaki, F; Mimura, M; Namiki, A; Sato, Y; Yamazaki, Y, 2001) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (3.23) | 18.2507 |
2000's | 7 (22.58) | 29.6817 |
2010's | 19 (61.29) | 24.3611 |
2020's | 4 (12.90) | 2.80 |
Authors | Studies |
---|---|
Li, YC | 1 |
Wang, R | 1 |
A, JY | 1 |
Sun, RB | 1 |
Na, SJ | 1 |
Liu, T | 1 |
Ding, XS | 1 |
Ge, WH | 1 |
Joys, S | 1 |
Panda, NB | 2 |
Ahuja, CK | 1 |
Luthra, A | 1 |
Tripathi, M | 1 |
Mahajan, S | 1 |
Kaloria, N | 1 |
Jain, C | 1 |
Singh, N | 1 |
Regmi, S | 1 |
Jangra, K | 2 |
Chauhan, R | 1 |
Soni, SL | 1 |
Bhagat, H | 3 |
Zhang, HB | 2 |
Tu, XK | 2 |
Chen, Q | 1 |
Shi, SS | 2 |
Balasubramanian, M | 1 |
Kuberan, A | 1 |
Rawat, A | 1 |
Dhandapani, S | 1 |
Panda, N | 1 |
Kumar, A | 1 |
Sahoo, AK | 1 |
Kumar, M | 1 |
Sharma, T | 1 |
Garcia, PS | 1 |
Kallioinen, M | 1 |
Posti, JP | 1 |
Rahi, M | 1 |
Sharma, D | 1 |
Katila, A | 1 |
Grönlund, J | 1 |
Vahlberg, T | 1 |
Frantzén, J | 1 |
Olkkola, KT | 1 |
Saari, TI | 1 |
Takala, R | 1 |
Bhardwaj, A | 1 |
Grover, VK | 1 |
Sahu, S | 1 |
Singla, N | 1 |
Lee, JW | 1 |
Woo, JH | 1 |
Baik, HJ | 1 |
Kim, DY | 1 |
Chae, JS | 1 |
Yang, NR | 1 |
Seo, EK | 1 |
Longhi, L | 1 |
Aresi, S | 1 |
Villa, F | 2 |
Citerio, G | 2 |
Sriganesh, K | 2 |
Reddy, M | 2 |
Jena, S | 1 |
Mittal, M | 1 |
Umamaheswara Rao, GS | 2 |
Banik, S | 1 |
Prabhakar, H | 1 |
Rosseland, LA | 1 |
Narum, J | 1 |
Stubhaug, A | 1 |
Kongsgaard, U | 1 |
Sorteberg, W | 1 |
Sorteberg, A | 1 |
Wang, CH | 1 |
Yang, WZ | 1 |
Liang, RS | 1 |
Chen, Y | 1 |
Zhang, L | 1 |
Jin, J | 1 |
Yao, J | 1 |
Yue, Z | 1 |
Wei, Y | 1 |
Yang, W | 1 |
Fu, S | 1 |
Li, W | 1 |
Hertle, DN | 1 |
Beynon, C | 1 |
Neumann, JO | 1 |
Santos, E | 1 |
Sánchez-Porras, R | 1 |
Unterberg, AW | 1 |
Sakowitz, OW | 1 |
Luo, F | 1 |
Ji, N | 1 |
Zhang, S | 1 |
Zhao, J | 1 |
Wang, T | 1 |
Skoglund, K | 1 |
Enblad, P | 1 |
Marklund, N | 1 |
Pisapia, JM | 1 |
Wendell, LC | 1 |
Kumar, MA | 1 |
Zager, EL | 1 |
Levine, JM | 1 |
Fernández-Torre, JL | 1 |
Hernández-Hernández, MA | 1 |
Stein, M | 1 |
Schomacher, J | 1 |
Scharbrodt, W | 1 |
Preuss, M | 1 |
Oertel, MF | 1 |
Iacca, C | 1 |
Molinari, AF | 1 |
Giussani, C | 1 |
Aletti, G | 1 |
Pesenti, A | 1 |
Lindgren, C | 1 |
Nordh, E | 1 |
Naredi, S | 1 |
Olivecrona, M | 1 |
Maas, AI | 1 |
Stocchetti, N | 1 |
Morishima, K | 1 |
Nakatani, K | 1 |
Nishi, Y | 1 |
Doi, A | 1 |
Yamama, Y | 1 |
Nakanishi, M | 1 |
Yagi, M | 1 |
Kurita, S | 1 |
Nagata, N | 1 |
Tanskanen, PE | 1 |
Kyttä, JV | 1 |
Randell, TT | 1 |
Schmieder, K | 1 |
Möller, F | 1 |
Engelhardt, M | 1 |
Scholz, M | 1 |
Schregel, W | 1 |
Christmann, A | 1 |
Harders, A | 1 |
Hoff, RG | 1 |
VAN Dijk, GW | 1 |
Mettes, S | 1 |
Verweij, BH | 1 |
Algra, A | 1 |
Rinkel, GJ | 1 |
Kalkman, CJ | 1 |
Lavine, SD | 1 |
Masri, LS | 1 |
Levy, ML | 1 |
Giannotta, SL | 1 |
Iwasaki, F | 1 |
Mimura, M | 1 |
Yamazaki, Y | 1 |
Hazama, K | 1 |
Sato, Y | 1 |
Namiki, A | 1 |
Sato, K | 1 |
Kato, M | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Inhalatorial Sedation in Patient With SAH Versus Conventional Intravenous Sedation (GAS-SAH)[NCT00830843] | Phase 4 | 13 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for propofol and Hemorrhage, Subarachnoid
Article | Year |
---|---|
[Anesthetic management for neurosurgery].
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Aneurysm, Ruptured; Brain Mapping; Craniotomy; Ep | 2001 |
6 trials available for propofol and Hemorrhage, Subarachnoid
Article | Year |
---|---|
Comparison of Effects of Propofol and Sevoflurane on the Cerebral Vasculature Assessed by Digital Subtraction Angiographic Parameters in Patients Treated for Ruptured Cerebral Aneurysm: A Preliminary Study.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Angiography, Digital Subtraction; Humans; | 2023 |
Effect of General Anesthetics on Caspase-3 Levels in Patients With Aneurysmal Subarachnoid Hemorrhage: A Preliminary Study.
Topics: Anesthetics, Inhalation; Caspase 3; Desflurane; Humans; Methyl Ethers; Pilot Projects; Propofol; Pro | 2021 |
Comparison of propofol and desflurane for postanaesthetic morbidity in patients undergoing surgery for aneurysmal SAH: a randomized clinical trial.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; Desflurane; Female; Fentan | 2018 |
A comparative study of dexmedetomidine and propofol as sole sedative agents for patients with aneurysmal subarachnoid hemorrhage undergoing diagnostic cerebral angiography.
Topics: Adult; Aged; Cerebral Angiography; Dexmedetomidine; Female; Heart Rate; Humans; Hypnotics and Sedati | 2015 |
Inhalation versus endovenous sedation in subarachnoid hemorrhage patients: effects on regional cerebral blood flow.
Topics: Academic Medical Centers; Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Flow | 2012 |
QT interval and QT dispersion during the induction of anaesthesia in patients with subarachnoid haemorrhage: a comparison of thiopental and propofol.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Arrhythmias, Cardiac; Electrocardiography; Female | 2002 |
24 other studies available for propofol and Hemorrhage, Subarachnoid
Article | Year |
---|---|
Cerebrospinal fluid metabolic profiling reveals divergent modulation of pentose phosphate pathway by midazolam, propofol and dexmedetomidine in patients with subarachnoid hemorrhage: a cohort study.
Topics: Aged; Cohort Studies; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Mid | 2022 |
Propofol Reduces Inflammatory Brain Injury after Subarachnoid Hemorrhage: Involvement of PI3K/Akt Pathway.
Topics: Animals; Anti-Inflammatory Agents; Brain; Brain Edema; Cyclooxygenase 2; Disease Models, Animal; Enc | 2019 |
Cerebral autoregulation after aneurysmal subarachnoid haemorrhage. A preliminary study comparing dexmedetomidine to propofol and/or midazolam.
Topics: Cerebrovascular Circulation; Dexmedetomidine; Homeostasis; Humans; Midazolam; Propofol; Subarachnoid | 2020 |
The effect of anesthetic agents on cerebral vasospasms after subarachnoid hemorrhage: A retrospective study.
Topics: Adult; Anesthetics; Desflurane; Female; Glasgow Coma Scale; Glasgow Outcome Scale; Humans; Intraoper | 2018 |
Volatile anesthetics following subarachnoid hemorrhage.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Cerebrovascular Circulation; Female; Humans; Isof | 2013 |
The authors reply.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Cerebrovascular Circulation; Female; Humans; Isof | 2013 |
Is dexmedetomidine really superior to propofol?
Topics: Cerebral Angiography; Dexmedetomidine; Female; Humans; Male; Propofol; Subarachnoid Hemorrhage | 2015 |
The effect of tracheotomy on drug consumption in patients with acute aneurysmal subarachnoid hemorrhage: an observational study.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Cerebrovascular Circulation; | 2015 |
In reply: is dexmedetomidine really superior to propofol?
Topics: Cerebral Angiography; Dexmedetomidine; Female; Humans; Male; Propofol; Subarachnoid Hemorrhage | 2015 |
Propofol Attenuates Early Brain Injury After Subarachnoid Hemorrhage in Rats.
Topics: Animals; Aquaporin 4; Blood-Brain Barrier; Cyclooxygenase 2; Interleukin-1beta; Male; Matrix Metallo | 2015 |
Effects of Propofol on Excitatory and Inhibitory Amino Acid Neurotransmitter Balance in Rats with Neurogenic Pulmonary Edema Induced by Subarachnoid Hemorrhage.
Topics: Animals; Brain; Brain Edema; Disease Models, Animal; Excitatory Amino Acids; gamma-Aminobutyric Acid | 2016 |
Use of GABAergic sedatives after subarachnoid hemorrhage is associated with worse outcome-preliminary findings.
Topics: Adult; Aged; Brain; Conscious Sedation; Female; Flunitrazepam; GABA Modulators; Glasgow Coma Scale; | 2016 |
Changes of endothelin and calcitonin gene-related peptide concentrations in plasma during propofol anesthesia.
Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Calcitonin Gene-Rela | 2009 |
Effects of the neurological wake-up test on intracranial pressure and cerebral perfusion pressure in brain-injured patients.
Topics: Adolescent; Adult; Aged; Brain Injuries; Diagnostic Techniques, Neurological; Female; Humans; Hypnot | 2009 |
Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage.
Topics: Adult; Biomarkers; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lactic Acid; Pro | 2011 |
Utility of bilateral Bispectral index (BIS) monitoring in a comatose patient with focal nonconvulsive status epilepticus.
Topics: Aged; Aneurysm, Ruptured; Coma; Consciousness Monitors; Deep Sedation; Electroencephalography; Femal | 2012 |
Cerebrospinal fluid lactate concentration after withdrawal of metabolic suppressive therapy in subarachnoid hemorrhage.
Topics: Adult; Aged; Female; Fentanyl; Glasgow Outcome Scale; Humans; Hypnotics and Sedatives; Intensive Car | 2012 |
Frequency of non-convulsive seizures and non-convulsive status epilepticus in subarachnoid hemorrhage patients in need of controlled ventilation and sedation.
Topics: Adolescent; Adult; Aged; Conscious Sedation; Critical Care; Electroencephalography; Female; Humans; | 2012 |
Beware of the Nottingham sheriff when manipulating cerebral blood flow in subarachnoid hemorrhage.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Cerebrovascular Circulation; Female; Humans; Isof | 2012 |
[Anesthetic management of a patient with thrombocytopenia induced by methotrexate undergoing emergent clipping surgery].
Topics: Aged; Anesthesia, General; Arthritis, Rheumatoid; Emergencies; Female; Humans; Immunosuppressive Age | 2012 |
Dynamic cerebral autoregulation in patients with ruptured and unruptured aneurysms after induction of general anesthesia.
Topics: Adult; Aged; Alfentanil; Anesthesia, General; Anesthetics, Intravenous; Aneurysm, Ruptured; Carbon D | 2006 |
Hypotension in anaesthetized patients during aneurysm clipping: not as bad as expected?
Topics: Anesthesia; Anesthetics, Intravenous; Anesthetics, Local; Atracurium; Cohort Studies; Etomidate; Fem | 2008 |
Temporary occlusion of the middle cerebral artery in intracranial aneurysm surgery: time limitation and advantage of brain protection.
Topics: Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Aneurysm, Ruptured; Brai | 1997 |
[Generalized tonic-clonic seizure induced by propofol in a patient with epilepsy].
Topics: Anesthesia, General; Anesthetics, Intravenous; Brachial Plexus; Epilepsy; Female; Humans; Middle Age | 2001 |