propofol has been researched along with Heart Disease, Ischemic in 59 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We hypothesized that sevoflurane compared with propofol reduces the incidence of myocardial ischemia in patients undergoing major noncardiac surgery." | 9.16 | Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery. ( Bolliger, D; Fassl, J; Filipovic, M; Kasper, J; Lurati Buse, GA; Schumacher, P; Schuman, RM; Seeberger, E; Seeberger, MD; Studer, W, 2012) |
| "This study compares remifentanil/propofol (remi/prop) with isoflurane/fentanyl (iso/fen) anesthesia to determine which provides the greater hemodynamic stability, lesser myocardial ischemia, and morbidity with better postoperative outcomes after carotid endarterectomy." | 9.10 | Hemodynamic stability, myocardial ischemia, and perioperative outcome after carotid surgery with remifentanil/propofol or isoflurane/fentanyl anesthesia. ( Baker, WH; Jellish, WS; Louie, EK; Sheikh, T; Slogoff, S, 2003) |
| "Inhalation anesthesia with sevoflurane seems superior to intravenous anesthesia with propofol in acute right ventricular ischemic dysfunction." | 7.83 | Sevoflurane anesthesia during acute right ventricular ischemia in pigs preserves cardiac function better than propofol anesthesia. ( Algotsson, L; Haraldsen, P; Ingemansson, R; Lindstedt, S; Metzsch, C, 2016) |
| "The anesthetic propofol confers cardioprotection against myocardial ischemia-reperfusion injury (IRI) by reducing reactive oxygen species (ROS)." | 7.81 | Effects of Glucose Concentration on Propofol Cardioprotection against Myocardial Ischemia Reperfusion Injury in Isolated Rat Hearts. ( Li, Y; Lin, J; Liu, HM; Tao, M; Wang, S; Xia, Z; Yao, X; Zhang, L, 2015) |
| "Propofol and fentanyl preconditioning can protect the heart against acute ischemia and promote the recovery of hemodynamics during hemorrhagic shock." | 7.75 | Pretreatment with fentanyl and propofol attenuates myocardial injury in rabbits with acute hemorrhagic shock. ( Chai, W; Kuai, J; Liu, X; Tao, L; Yang, Y; Yao, L; Yu, D; Zeng, X, 2009) |
| "The authors' results suggest that propofol preserves connexin 43 phosphorylation during acute myocardial ischemia, as compared with sevoflurane, and this might protect the heart from serious ventricular arrhythmias during acute coronary occlusion." | 7.75 | Differential effects of propofol and sevoflurane on ischemia-induced ventricular arrhythmias and phosphorylated connexin 43 protein in rats. ( Hirata, N; Kamada, N; Kanaya, N; Kimura, S; Namiki, A, 2009) |
| " The results of this trial suggest that a propofol-based anesthetic, when compared to an enflurane-based anesthetic requiring additional dosing of fentanyl and midazolam for CPB, can lead to a significant reduction in time to extubation after CABG surgery, without adverse hemodynamic effects, increased risk of myocardial ischemia or infarction." | 6.68 | Hemodynamic effects, myocardial ischemia, and timing of tracheal extubation with propofol-based anesthesia for cardiac surgery. ( Buckland, MR; Bujor, MA; Davis, BB; Hunt, JO; Langley, M; McRae, R; Moloney, JT; Myles, PS; Weeks, AM, 1997) |
| "Propofol could inhibit NF-kappaB activation and down-regulate the expression of caspase-3 and as a result suppress cardiomyocytes apoptotic initiation during the myocardium I/R injury, which may be one of the molecular mechanisms of its cardioprotection." | 5.36 | [Effects of propofol on the activation of nuclear factor-kappaB and cardiomyocytes apoptosis during myocardial ischemia/reperfusion injury in rats]. ( Li, LF; Xie, LJ; Zhang, JX; Zhao, S, 2010) |
| " We hypothesized that sevoflurane compared with propofol reduces the incidence of myocardial ischemia in patients undergoing major noncardiac surgery." | 5.16 | Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery. ( Bolliger, D; Fassl, J; Filipovic, M; Kasper, J; Lurati Buse, GA; Schumacher, P; Schuman, RM; Seeberger, E; Seeberger, MD; Studer, W, 2012) |
| "This study compares remifentanil/propofol (remi/prop) with isoflurane/fentanyl (iso/fen) anesthesia to determine which provides the greater hemodynamic stability, lesser myocardial ischemia, and morbidity with better postoperative outcomes after carotid endarterectomy." | 5.10 | Hemodynamic stability, myocardial ischemia, and perioperative outcome after carotid surgery with remifentanil/propofol or isoflurane/fentanyl anesthesia. ( Baker, WH; Jellish, WS; Louie, EK; Sheikh, T; Slogoff, S, 2003) |
| " clonidine, in addition to general anesthesia, affects the cardiopulmonary bypass- and surgery-associated stress response and incidence of myocardial ischemia by their sympatholytic properties." | 5.09 | High thoracic epidural anesthesia, but not clonidine, attenuates the perioperative stress response via sympatholysis and reduces the release of troponin T in patients undergoing coronary artery bypass grafting. ( Berendes, E; Erren, M; Junker, R; Loick, HM; Meissner, A; Möllhoff, T; Rolf, N; Scheld, HH; Schmid, C; Schmidt, C; Van Aken, H, 1999) |
| " There was no difference in the incidence of breakthrough hypertension between the two groups (in 44% and 43% of the patients, respectively) and in the number of alfentanil bolus supplements." | 5.08 | Continuous infusions of alfentanil and propofol for coronary artery surgery. ( de Lange, S; Gerrits, HJ; Roekaerts, PM; Timmerman, BE, 1995) |
| " Cardiac morbidity (postoperative myocardial ischemia, postoperative myocardial infarction, and perioperative sympathoadrenal stress response), respiratory morbidity (postextubation apnea, alveolar-arterial oxygen gradient, pulmonary shunting, oxygen consumption, atelectasis, and reintubation), hemodynamic values and vasoactive medication requirements, intraoperative awareness, postoperative cognitive function, 30 day mortality, and intensive care unit and hospital lengths of stay were compared between the two groups." | 5.08 | Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial. ( Asokumar, B; Carroll, J; Cheng, DC; David, T; Karski, J; Mickle, D; Nierenberg, H; Peniston, C; Raveendran, G; Roger, S; Sandler, A; Tong, J; Zelovitsky, J, 1996) |
| "This randomized study of patients after coronary artery bypass surgery examined whether light (versus heavy) sedation with propofol in the intensive care unit was associated with an increased degree of myocardial ischemia." | 5.08 | Light versus heavy sedation after cardiac surgery: myocardial ischemia and the stress response. Maritime Heart Centre and Dalhousie University. ( Ali, I; Allen, CT; Hall, RI; Kinley, E; MacLaren, C; McIntyre, AJ; Murphy, JT; Smith, MS; Sullivan, J; Wood, J, 1997) |
| "Inhalation anesthesia with sevoflurane seems superior to intravenous anesthesia with propofol in acute right ventricular ischemic dysfunction." | 3.83 | Sevoflurane anesthesia during acute right ventricular ischemia in pigs preserves cardiac function better than propofol anesthesia. ( Algotsson, L; Haraldsen, P; Ingemansson, R; Lindstedt, S; Metzsch, C, 2016) |
| "The anesthetic propofol confers cardioprotection against myocardial ischemia-reperfusion injury (IRI) by reducing reactive oxygen species (ROS)." | 3.81 | Effects of Glucose Concentration on Propofol Cardioprotection against Myocardial Ischemia Reperfusion Injury in Isolated Rat Hearts. ( Li, Y; Lin, J; Liu, HM; Tao, M; Wang, S; Xia, Z; Yao, X; Zhang, L, 2015) |
| "Propofol and fentanyl preconditioning can protect the heart against acute ischemia and promote the recovery of hemodynamics during hemorrhagic shock." | 3.75 | Pretreatment with fentanyl and propofol attenuates myocardial injury in rabbits with acute hemorrhagic shock. ( Chai, W; Kuai, J; Liu, X; Tao, L; Yang, Y; Yao, L; Yu, D; Zeng, X, 2009) |
| "The authors' results suggest that propofol preserves connexin 43 phosphorylation during acute myocardial ischemia, as compared with sevoflurane, and this might protect the heart from serious ventricular arrhythmias during acute coronary occlusion." | 3.75 | Differential effects of propofol and sevoflurane on ischemia-induced ventricular arrhythmias and phosphorylated connexin 43 protein in rats. ( Hirata, N; Kamada, N; Kanaya, N; Kimura, S; Namiki, A, 2009) |
| "Clonidine was associated with a significant (P < 0." | 2.69 | Clonidine and cardiac surgery: haemodynamic and metabolic effects, myocardial ischaemia and recovery. ( Buckland, MR; Bujor, MA; Davis, BB; Esmore, DS; Hall, J; Holdgaard, HO; Hunt, JO; McRae, R; Moloney, J; Morgan, DJ; Myles, PS, 1999) |
| "Myocardial ischemia was assessed perioperatively by monitoring ST segment deviation via continuous three-lead Holter electrocardiography, and it was evaluated during operation by monitoring left ventricular wall motion abnormality via transesophageal echocardiography." | 2.68 | Multicenter study of target-controlled infusion of propofol-sufentanil or sufentanil-midazolam for coronary artery bypass graft surgery. Multicenter Study of Perioperative Ischemia (McSPI) Research Group. ( Bellows, W; Body, SC; Jain, U; Mangano, CM; Mangano, DT; Mathew, J; Wilson, R; Wolman, R; Youngs, E; Zhang, A, 1996) |
| " The results of this trial suggest that a propofol-based anesthetic, when compared to an enflurane-based anesthetic requiring additional dosing of fentanyl and midazolam for CPB, can lead to a significant reduction in time to extubation after CABG surgery, without adverse hemodynamic effects, increased risk of myocardial ischemia or infarction." | 2.68 | Hemodynamic effects, myocardial ischemia, and timing of tracheal extubation with propofol-based anesthesia for cardiac surgery. ( Buckland, MR; Bujor, MA; Davis, BB; Hunt, JO; Langley, M; McRae, R; Moloney, JT; Myles, PS; Weeks, AM, 1997) |
| " The dosage of each drug was 10 mg/kg." | 1.38 | Effects of propofol on ischemia-induced ventricular arrhythmias and mitochondrial ATP-sensitive potassium channels. ( Chen, R; Hong, J; Li, XY; Liu, Q; Liu, SW; Qian, C; Song, LS; Sun, BG; Yao, JY, 2012) |
| "Propofol could inhibit NF-kappaB activation and down-regulate the expression of caspase-3 and as a result suppress cardiomyocytes apoptotic initiation during the myocardium I/R injury, which may be one of the molecular mechanisms of its cardioprotection." | 1.36 | [Effects of propofol on the activation of nuclear factor-kappaB and cardiomyocytes apoptosis during myocardial ischemia/reperfusion injury in rats]. ( Li, LF; Xie, LJ; Zhang, JX; Zhao, S, 2010) |
| "Propofol treatment attenuated the changes in myocardial tissue levels of adenine nucleotides, lactate, and amino acids during ischemia and reduced cardiac troponin I release on reperfusion." | 1.33 | Propofol is cardioprotective in a clinically relevant model of normothermic blood cardioplegic arrest and cardiopulmonary bypass. ( Angelini, GD; Halestrap, AP; Lim, KH; Suleiman, MS, 2005) |
| "Propofol in KH was perfused at 12 microg/ml for the first 15 min of reperfusion and subsequently reduced to 5 microg/ml in propofol treatment groups." | 1.32 | Propofol enhances ischemic tolerance of middle-aged rat hearts: effects on 15-F(2t)-isoprostane formation and tissue antioxidant capacity. ( Ansley, DM; Godin, DV; Xia, Z, 2003) |
| "Propofol was given by 10 mg/kg intravenous bolus followed by 30 min infusion in succession with 20 mg/kg/hr, 40 mg/kg/hr and 80 mg/kg/hr in both normal hearts and hearts with coronary ligation." | 1.29 | Cardiovascular effects of propofol during coronary ligation in anesthetized dogs. ( Chen, TL; Cheng, YJ; Fan, SZ; Tan, PP; Wang, YP, 1993) |
| "Extracranial mycotic aneurysms of the carotid are unusual." | 1.29 | [Cervical epidural anesthesia for carotid mycotic aneurysms]. ( Bronte, E; Carpintero, M; Giménez, C; Llorente, A; Ramos, G, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 24 (40.68) | 18.2507 |
| 2000's | 18 (30.51) | 29.6817 |
| 2010's | 17 (28.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guerrero-Orriach, JL | 1 |
| Escalona Belmonte, JJ | 1 |
| Ramirez Fernandez, A | 1 |
| Ramirez Aliaga, M | 1 |
| Rubio Navarro, M | 1 |
| Cruz Mañas, J | 1 |
| Benstoem, C | 1 |
| Goetzenich, A | 1 |
| Stoppe, C | 1 |
| Gajardo, AIJ | 1 |
| Karachon, L | 1 |
| Bustamante, P | 1 |
| Repullo, P | 1 |
| Llancaqueo, M | 1 |
| Sánchez, G | 1 |
| Rodrigo, R | 1 |
| Ma, K | 1 |
| Qiu, J | 1 |
| Zhou, M | 1 |
| Yang, Y | 2 |
| Ye, X | 1 |
| Zaugg, M | 1 |
| Lucchinetti, E | 1 |
| Zhang, JL | 1 |
| Hua, D | 1 |
| Yang, JP | 1 |
| Ruggieri, F | 1 |
| Cappelleri, G | 1 |
| Cornaggia, G | 1 |
| Lurati Buse, GA | 2 |
| Schumacher, P | 2 |
| Seeberger, E | 2 |
| Studer, W | 2 |
| Schuman, RM | 2 |
| Fassl, J | 2 |
| Kasper, J | 2 |
| Filipovic, M | 2 |
| Bolliger, D | 2 |
| Seeberger, MD | 2 |
| LeBlanc, JM | 1 |
| Lalonde, D | 1 |
| Cameron, K | 1 |
| Mowatt, JA | 1 |
| Yao, X | 1 |
| Li, Y | 1 |
| Tao, M | 1 |
| Wang, S | 1 |
| Zhang, L | 1 |
| Lin, J | 1 |
| Xia, Z | 4 |
| Liu, HM | 1 |
| Zhang, J | 1 |
| Wang, Z | 1 |
| Ji, Y | 1 |
| Qian, H | 1 |
| Dong, N | 1 |
| Haraldsen, P | 1 |
| Metzsch, C | 1 |
| Lindstedt, S | 1 |
| Algotsson, L | 1 |
| Ingemansson, R | 1 |
| Onk, D | 1 |
| Akarsu Ayazoğlu, T | 1 |
| Onk, OA | 1 |
| Aksüt, M | 1 |
| Günay, M | 1 |
| Turkmen, K | 1 |
| Özensoy, A | 1 |
| Yazıcı Ersoy, Ç | 1 |
| Çoban, A | 1 |
| Yao, L | 1 |
| Kuai, J | 1 |
| Liu, X | 1 |
| Yu, D | 1 |
| Tao, L | 1 |
| Zeng, X | 1 |
| Chai, W | 1 |
| Hirata, N | 1 |
| Kanaya, N | 1 |
| Kamada, N | 1 |
| Kimura, S | 1 |
| Namiki, A | 1 |
| Yao, YT | 1 |
| Li, LH | 1 |
| Zhao, S | 1 |
| Xie, LJ | 2 |
| Zhang, JX | 2 |
| Li, LF | 2 |
| Liu, Q | 1 |
| Yao, JY | 1 |
| Qian, C | 1 |
| Chen, R | 1 |
| Li, XY | 1 |
| Liu, SW | 1 |
| Sun, BG | 1 |
| Song, LS | 1 |
| Hong, J | 1 |
| Kersten, JR | 1 |
| Kato, R | 1 |
| Foëx, P | 4 |
| Hack, H | 1 |
| Morishima, T | 1 |
| Sobue, K | 1 |
| Arima, H | 1 |
| Tanaka, S | 1 |
| So, M | 1 |
| Ando, H | 1 |
| Katsuya, H | 1 |
| Saito, S | 1 |
| Kadoi, Y | 1 |
| Nihishara, F | 1 |
| Aso, C | 1 |
| Goto, F | 1 |
| Godin, DV | 3 |
| Chang, TK | 1 |
| Ansley, DM | 3 |
| Jellish, WS | 1 |
| Sheikh, T | 1 |
| Baker, WH | 1 |
| Louie, EK | 1 |
| Slogoff, S | 1 |
| Kendall, JB | 1 |
| Russell, GN | 1 |
| Scawn, ND | 1 |
| Akrofi, M | 1 |
| Cowan, CM | 1 |
| Fox, MA | 1 |
| Kuzumoto, N | 1 |
| Kitagawa, Y | 1 |
| Uemura, K | 1 |
| Ueyama, T | 1 |
| Yoshida, K | 1 |
| Furuya, H | 1 |
| Takaki, M | 1 |
| Barrington, MJ | 1 |
| Kluger, R | 1 |
| Watson, R | 1 |
| Scott, DA | 1 |
| Harris, KJ | 1 |
| Lim, KH | 1 |
| Halestrap, AP | 1 |
| Angelini, GD | 1 |
| Suleiman, MS | 1 |
| Roy, N | 1 |
| Friehs, I | 1 |
| Cowan, DB | 1 |
| Zurakowski, D | 1 |
| McGowan, FX | 1 |
| del Nido, PJ | 1 |
| McDermott, BJ | 1 |
| McWilliams, S | 1 |
| Smyth, K | 1 |
| Kelso, EJ | 1 |
| Spiers, JP | 1 |
| Zhao, Y | 1 |
| Bell, D | 1 |
| Mirakhur, RK | 1 |
| Archer, DP | 1 |
| Tang, TK | 1 |
| Mutch, WA | 1 |
| White, IW | 1 |
| Donen, N | 1 |
| Thomson, IR | 1 |
| Rosenbloom, M | 1 |
| Cheang, M | 1 |
| West, M | 1 |
| Roekaerts, PM | 1 |
| Gerrits, HJ | 1 |
| Timmerman, BE | 1 |
| de Lange, S | 1 |
| Vermeyen, KM | 1 |
| De Hert, SG | 1 |
| Adriaensen, HF | 1 |
| Cheng, YJ | 1 |
| Fan, SZ | 1 |
| Chen, TL | 1 |
| Wang, YP | 1 |
| Tan, PP | 1 |
| Gordon, PC | 1 |
| Morrell, DF | 1 |
| Pamm, JD | 1 |
| Goldberg, AH | 1 |
| Diedericks, J | 2 |
| Sear, JW | 2 |
| Hopwood, MB | 1 |
| Lischke, V | 1 |
| Probst, S | 1 |
| Behne, M | 1 |
| Kessler, P | 1 |
| Leone, BJ | 1 |
| Ryder, WA | 2 |
| Llorente, A | 1 |
| Bronte, E | 1 |
| Ramos, G | 1 |
| Carpintero, M | 1 |
| Giménez, C | 1 |
| Daniel, M | 1 |
| Eger, EI | 1 |
| Weiskopf, RB | 1 |
| Noorani, M | 1 |
| Wahr, JA | 1 |
| Plunkett, JJ | 1 |
| Ramsay, JG | 1 |
| Reeves, J | 1 |
| Jain, U | 2 |
| Ley, C | 1 |
| Wilson, R | 2 |
| Mangano, DT | 2 |
| Chan, VW | 1 |
| Chung, FF | 1 |
| Coetzee, A | 1 |
| Cheng, DC | 1 |
| Karski, J | 1 |
| Peniston, C | 1 |
| Asokumar, B | 1 |
| Raveendran, G | 1 |
| Carroll, J | 1 |
| Nierenberg, H | 1 |
| Roger, S | 1 |
| Mickle, D | 1 |
| Tong, J | 1 |
| Zelovitsky, J | 1 |
| David, T | 1 |
| Sandler, A | 1 |
| Body, SC | 1 |
| Bellows, W | 1 |
| Wolman, R | 1 |
| Mangano, CM | 1 |
| Mathew, J | 1 |
| Youngs, E | 1 |
| Zhang, A | 1 |
| Myles, PS | 2 |
| Buckland, MR | 2 |
| Weeks, AM | 1 |
| Bujor, MA | 2 |
| McRae, R | 2 |
| Langley, M | 1 |
| Moloney, JT | 1 |
| Hunt, JO | 2 |
| Davis, BB | 2 |
| Ko, SH | 1 |
| Yu, CW | 1 |
| Lee, SK | 1 |
| Choe, H | 1 |
| Chung, MJ | 1 |
| Kwak, YG | 1 |
| Chae, SW | 1 |
| Song, HS | 1 |
| Hall, RI | 1 |
| MacLaren, C | 1 |
| Smith, MS | 1 |
| McIntyre, AJ | 1 |
| Allen, CT | 1 |
| Murphy, JT | 1 |
| Sullivan, J | 1 |
| Wood, J | 1 |
| Ali, I | 1 |
| Kinley, E | 1 |
| Darvas, K | 1 |
| Molnár, Z | 1 |
| Irtó, I | 1 |
| Tarjányi, M | 1 |
| Flautner, L | 1 |
| Ross, S | 1 |
| Muñoz, H | 1 |
| Piriou, V | 1 |
| Loick, HM | 1 |
| Schmidt, C | 1 |
| Van Aken, H | 1 |
| Junker, R | 1 |
| Erren, M | 1 |
| Berendes, E | 1 |
| Rolf, N | 1 |
| Meissner, A | 1 |
| Schmid, C | 1 |
| Scheld, HH | 1 |
| Möllhoff, T | 1 |
| Holdgaard, HO | 1 |
| Moloney, J | 1 |
| Hall, J | 1 |
| Esmore, DS | 1 |
| Morgan, DJ | 1 |
| Wasnick, JD | 1 |
| Haile, KK | 1 |
| Acuff, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multi-Center Trial on the Effect of Anesthetics on Morbidity and Mortality in Patients Undergoing Major Non-cardiac Surgery[NCT00286585] | Phase 4 | 385 participants (Actual) | Interventional | 2006-02-28 | Completed | ||
| Perioperative Multimodal General Anesthesia Focusing on Specific CNS Targets in Patients Undergoing Cardiac Surgeries[NCT04016740] | Early Phase 1 | 22 participants (Actual) | Interventional | 2019-08-20 | Completed | ||
| Changes of Hemodynamics and Vital Organ Function in Intracerebral Hemorrhage During Different General Anesthesia[NCT03129009] | 90 participants (Anticipated) | Interventional | 2017-04-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for propofol and Heart Disease, Ischemic
| Article | Year |
|---|---|
Cardioprotection with halogenated gases: how does it occur?
Topics: Animals; Cardiotonic Agents; Gases; Humans; Methyl Ethers; Myocardial Ischemia; Propofol; Sevofluran | 2017 |
The role of propofol for remote ischaemic preconditioning in the setting of cardiac surgery - a Cochrane systematic review.
Topics: Anesthetics, Intravenous; Cardiac Surgical Procedures; Humans; Ischemic Preconditioning, Myocardial; | 2017 |
Sevoflurane versus propofol for myocardial protection in patients undergoing coronary artery bypass grafting surgery: a meta-analysis of randomized controlled trials.
Topics: Adult; Anesthetics; Cardiotonic Agents; Coronary Artery Bypass; Humans; Methyl Ethers; Myocardial Is | 2009 |
Myocardial protection by anesthetic agents against ischemia-reperfusion injury: an update for anesthesiologists.
Topics: Analgesics, Opioid; Anesthetics; Animals; Coronary Vessels; Humans; Ischemic Preconditioning, Myocar | 2002 |
18 trials available for propofol and Heart Disease, Ischemic
| Article | Year |
|---|---|
Comparison of TIVA and Desflurane Added to a Subanaesthetic Dose of Propofol in Patients Undergoing Coronary Artery Bypass Surgery: Evaluation of Haemodynamic and Stress Hormone Changes.
Topics: Aged; Aged, 80 and over; Anesthesia, Intravenous; Anesthetics, Inhalation; Aorta; Biomarkers; Body M | 2016 |
Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery.
Topics: Aged; Aged, 80 and over; Anesthetics; Female; Follow-Up Studies; Humans; Intraoperative Complication | 2012 |
Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery.
Topics: Aged; Aged, 80 and over; Anesthetics; Female; Follow-Up Studies; Humans; Intraoperative Complication | 2012 |
Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery.
Topics: Aged; Aged, 80 and over; Anesthetics; Female; Follow-Up Studies; Humans; Intraoperative Complication | 2012 |
Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery.
Topics: Aged; Aged, 80 and over; Anesthetics; Female; Follow-Up Studies; Humans; Intraoperative Complication | 2012 |
End-tidal carbon dioxide monitoring stabilized hemodynamic changes during ECT.
Topics: Adult; Aged; Anesthetics, Intravenous; Brain; Brain Diseases; Carbon Dioxide; Electroconvulsive Ther | 2003 |
Hemodynamic stability, myocardial ischemia, and perioperative outcome after carotid surgery with remifentanil/propofol or isoflurane/fentanyl anesthesia.
Topics: Aged; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Carotid Artery Disea | 2003 |
A prospective, randomised, single-blind pilot study to determine the effect of anaesthetic technique on troponin T release after off-pump coronary artery surgery.
Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2004 |
Epidural anesthesia for coronary artery bypass surgery compared with general anesthesia alone does not reduce biochemical markers of myocardial damage.
Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenous; Biomarkers; Cardiomyopath | 2005 |
Haemodynamic instability and myocardial ischaemia during carotid endarterectomy: a comparison of propofol and isoflurane.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave | 1995 |
Continuous infusions of alfentanil and propofol for coronary artery surgery.
Topics: Alfentanil; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Coron | 1995 |
[ST segment changes in the ECG. Anesthesia induction with propofol, etomidate or midazolam in patients with coronary heart disease].
Topics: Aged; Anesthesia; Blood Pressure; Coronary Artery Bypass; Electrocardiography; Etomidate; Female; Fe | 1993 |
Propofol fails to attenuate the cardiovascular response to rapid increases in desflurane concentration.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Desflurane; Dose-Response Rela | 1996 |
Cardiovascular responses during sedation after coronary revascularization. Incidence of myocardial ischemia and hemodynamic episodes with propofol versus midazolam. Institutions of the McSPI Research Group.
Topics: Adult; Aged; Double-Blind Method; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Incidence; | 1996 |
Propofol infusion for induction and maintenance of anesthesia in elderly patients: recovery and hemodynamic profiles.
Topics: Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Int | 1996 |
Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial.
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Apnea; Catecholamines; | 1996 |
Multicenter study of target-controlled infusion of propofol-sufentanil or sufentanil-midazolam for coronary artery bypass graft surgery. Multicenter Study of Perioperative Ischemia (McSPI) Research Group.
Topics: Aged; Anesthetics, Intravenous; Coronary Artery Bypass; Electrocardiography; Female; Hemodynamics; H | 1996 |
Hemodynamic effects, myocardial ischemia, and timing of tracheal extubation with propofol-based anesthesia for cardiac surgery.
Topics: Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Coronary Artery Bypass; Enflura | 1997 |
Light versus heavy sedation after cardiac surgery: myocardial ischemia and the stress response. Maritime Heart Centre and Dalhousie University.
Topics: Aged; Analgesia; Coronary Artery Bypass; Dose-Response Relationship, Drug; Female; Humans; Hypnotics | 1997 |
High thoracic epidural anesthesia, but not clonidine, attenuates the perioperative stress response via sympatholysis and reduces the release of troponin T in patients undergoing coronary artery bypass grafting.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Anesthesia, Epidural; Anesthesia, General | 1999 |
Clonidine and cardiac surgery: haemodynamic and metabolic effects, myocardial ischaemia and recovery.
Topics: Adrenergic alpha-Agonists; Aged; Anesthetics, Intravenous; Clonidine; Coronary Artery Bypass; Creati | 1999 |
37 other studies available for propofol and Heart Disease, Ischemic
| Article | Year |
|---|---|
Autonomic imbalance in cardiac surgery: A potential determinant of the failure in remote ischemic preconditioning.
Topics: Animals; Cardiac Surgical Procedures; Chronic Disease; Comorbidity; Heart; Humans; Ischemic Precondi | 2018 |
Cox-2 Negatively Affects the Protective Role of Propofol against Hypoxia/Reoxygenation Induced Cardiomyocytes Apoptosis through Suppressing Akt Signaling.
Topics: Animals; Apoptosis; Cell Hypoxia; Cell Survival; Cyclooxygenase 2; Gene Expression Regulation; Human | 2019 |
Letter by Zaugg and Lucchinetti regarding article, "Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery".
Topics: Female; Humans; Intraoperative Complications; Male; Methyl Ethers; Myocardial Ischemia; Perioperativ | 2013 |
Letter by Zhang et al regarding article, "Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery".
Topics: Female; Humans; Intraoperative Complications; Male; Methyl Ethers; Myocardial Ischemia; Perioperativ | 2013 |
Letter by Ruggieri et al regarding article, "Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery".
Topics: Female; Humans; Intraoperative Complications; Male; Methyl Ethers; Myocardial Ischemia; Perioperativ | 2013 |
Response to letters regarding article, “Randomized comparison of sevoflurane versus propofol to reduce perioperative myocardial ischemia in patients undergoing noncardiac surgery".
Topics: Female; Humans; Intraoperative Complications; Male; Methyl Ethers; Myocardial Ischemia; Perioperativ | 2013 |
Tissue necrosis after propofol extravasation.
Topics: Anesthetics, Intravenous; Aneurysm; Comorbidity; Diabetes Mellitus; Extravasation of Diagnostic and | 2014 |
Effects of Glucose Concentration on Propofol Cardioprotection against Myocardial Ischemia Reperfusion Injury in Isolated Rat Hearts.
Topics: Animals; Dose-Response Relationship, Drug; Glucose; Heart; Male; Myocardial Contraction; Myocardial | 2015 |
[Risk analysis of cardiovascular events in elderly hypertensive patients with different risk stratification during the perioperative period].
Topics: Aged; Anesthesia, General; Cardiac Output; Cardiovascular Diseases; Coronary Artery Disease; Fentany | 2015 |
Sevoflurane anesthesia during acute right ventricular ischemia in pigs preserves cardiac function better than propofol anesthesia.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cardiac Output; Coronary Cir | 2016 |
Pretreatment with fentanyl and propofol attenuates myocardial injury in rabbits with acute hemorrhagic shock.
Topics: Anesthetics, Intravenous; Animals; Female; Fentanyl; Hemodynamics; Ischemic Preconditioning, Myocard | 2009 |
Differential effects of propofol and sevoflurane on ischemia-induced ventricular arrhythmias and phosphorylated connexin 43 protein in rats.
Topics: Animals; Arrhythmias, Cardiac; Connexin 43; Heart Rate; Male; Methyl Ethers; Myocardial Ischemia; Ph | 2009 |
[Effects of propofol on the activation of nuclear factor-kappaB and cardiomyocytes apoptosis during myocardial ischemia/reperfusion injury in rats].
Topics: Animals; Apoptosis; Caspase 3; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, C | 2010 |
[Effects of propofol on cardiomyocytes apoptosis and its mechanism after ischemia/reperfusion injury in isolated rat hearts].
Topics: Anesthetics, Intravenous; Animals; Apoptosis; In Vitro Techniques; Male; Myocardial Ischemia; Myocar | 2008 |
Effects of propofol on ischemia-induced ventricular arrhythmias and mitochondrial ATP-sensitive potassium channels.
Topics: Animals; Cells, Cultured; Electrocardiography; Hemodynamics; KATP Channels; Male; Membrane Potential | 2012 |
A recipe for perioperative cardioprotection: what matters most? The ingredients or the chef?
Topics: Female; Humans; Intraoperative Complications; Male; Methyl Ethers; Myocardial Ischemia; Perioperativ | 2012 |
Propofol as an antiarrhythmic.
Topics: Aged; Anti-Arrhythmia Agents; Heart Block; Humans; Male; Myocardial Ischemia; Propofol; Tachycardia, | 2002 |
Profound pain due to propofol injection triggered myocardial ischemia in a patient with a suspected pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Anesthetics, Intravenous; Electrocardiography; Humans; Male; Myocard | 2003 |
Dose-dependent protection of cardiac function by propofol during ischemia and early reperfusion in rats: effects on 15-F2t-isoprostane formation.
Topics: Anesthetics, Intravenous; Animals; Antioxidants; Dinoprost; Dose-Response Relationship, Drug; F2-Iso | 2003 |
Propofol enhances ischemic tolerance of middle-aged rat hearts: effects on 15-F(2t)-isoprostane formation and tissue antioxidant capacity.
Topics: Aging; Animals; Antioxidants; Disease Susceptibility; Male; Myocardial Ischemia; Myocardial Reperfus | 2003 |
A brief regional ischemic-reperfusion enhances propofol-induced depression in left ventricular function of in situ rat hearts.
Topics: Anesthetics, Intravenous; Animals; Depression, Chemical; Male; Myocardial Ischemia; Myocardial Reper | 2004 |
Application of high-dose propofol during ischemia improves postischemic function of rat hearts: effects on tissue antioxidant capacity.
Topics: Animals; Antioxidants; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardium; Propofol; | 2004 |
Propofol is cardioprotective in a clinically relevant model of normothermic blood cardioplegic arrest and cardiopulmonary bypass.
Topics: Anesthetics, Intravenous; Animals; Body Temperature; Cardioplegic Solutions; Cardiopulmonary Bypass; | 2005 |
Dopamine induces postischemic cardiomyocyte apoptosis in vivo: an effect ameliorated by propofol.
Topics: Anesthetics, Intravenous; Animals; Apoptosis; Cardiotonic Agents; Cold Ischemia; Dopamine; Heart Tra | 2006 |
Protection of cardiomyocyte function by propofol during simulated ischemia is associated with a direct action to reduce pro-oxidant activity.
Topics: Animals; Hydrogen Peroxide; Lipid Peroxidation; Male; Myocardial Contraction; Myocardial Ischemia; P | 2007 |
The choice of anaesthetic for carotid endarterectomy: does it matter?
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 1995 |
Onset of segmental relaxation dysfunction with decreased myocardial tissue perfusion: modulation by propofol.
Topics: Anesthetics, Intravenous; Animals; Coronary Circulation; Disease Models, Animal; Dogs; Heart Rate; H | 1995 |
Cardiovascular effects of propofol during coronary ligation in anesthetized dogs.
Topics: Anesthesia; Animals; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Ligation; Male; M | 1993 |
Total intravenous anesthesia using propofol and alfentanil for coronary artery bypass surgery.
Topics: Adult; Aged; Alfentanil; Anesthesia Recovery Period; Anesthesia, Intravenous; Awareness; Blood Press | 1994 |
Diltiazem and regional left ventricular function during graded coronary constriction and propofol anesthesia in the dog.
Topics: Anesthesia, Intravenous; Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Diltiazem; D | 1993 |
Nitrous oxide causes myocardial ischemia when added to propofol in the compromised canine myocardium.
Topics: Anesthesia, Intravenous; Animals; Coronary Circulation; Dogs; Male; Myocardial Ischemia; Nitrous Oxi | 1993 |
[Cervical epidural anesthesia for carotid mycotic aneurysms].
Topics: Aged; Anesthesia, Epidural; Aneurysm, Infected; Carotid Artery Diseases; Carotid Artery, Internal; C | 1995 |
Comparison of the effects of propofol and halothane on acute myocardial ischaemia and myocardial reperfusion injury.
Topics: Anesthetics, Inhalation; Animals; Free Radical Scavengers; Halothane; Myocardial Ischemia; Propofol; | 1996 |
Propofol attenuates ischemia-reperfusion injury in the isolated rat heart.
Topics: Anesthetics, Intravenous; Animals; Coronary Circulation; L-Lactate Dehydrogenase; Male; Myocardial I | 1997 |
Anaesthesiological indications and contraindications of minimally invasive surgery.
Topics: Acid-Base Equilibrium; Acidosis; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenou | 1997 |
A comparison of the effects of fentanyl and propofol on left ventricular contractility during myocardial stunning.
Topics: Anesthetics, Intravenous; Animals; Aorta; Blood Pressure; Calcium Channel Blockers; Cardiac Output; | 1998 |
Anesthetic management of minimally invasive laser transmyocardial revascularization.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Angina Pectoris; Desflurane; | 1999 |