propofol has been researched along with Health Care Associated Infection in 26 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We presented a sepsis outbreak caused by Serratia marcescens from contaminated propofol to raise awareness." | 7.91 | Serratia marcescens sepsis outbreak caused by contaminated propofol. ( Aksit-Barik, S; Arda, B; Cilli, F; Gulay, Z; Kepeli, N; Nazli-Zeka, A; Ozinel, MA; Sipahi, OR; Ulusoy, S, 2019) |
| "We conducted an in vitro trial by collecting IV tubing sets at the time of patient discharge from same-day ambulatory procedures performed with and without propofol anesthesia." | 7.81 | Leaving more than your fingerprint on the intravenous line: a prospective study on propofol anesthesia and implications of stopcock contamination. ( Baslanti, TO; Cole, DC; Gravenstein, N; Gravenstein, NL, 2015) |
| "We presented a sepsis outbreak caused by Serratia marcescens from contaminated propofol to raise awareness." | 3.91 | Serratia marcescens sepsis outbreak caused by contaminated propofol. ( Aksit-Barik, S; Arda, B; Cilli, F; Gulay, Z; Kepeli, N; Nazli-Zeka, A; Ozinel, MA; Sipahi, OR; Ulusoy, S, 2019) |
| "We conducted an in vitro trial by collecting IV tubing sets at the time of patient discharge from same-day ambulatory procedures performed with and without propofol anesthesia." | 3.81 | Leaving more than your fingerprint on the intravenous line: a prospective study on propofol anesthesia and implications of stopcock contamination. ( Baslanti, TO; Cole, DC; Gravenstein, N; Gravenstein, NL, 2015) |
| "Sepsis and postoperative infection can occur as a result of unsafe practices in the administration of propofol and other injectable medications." | 3.78 | Safe injection practices for administration of propofol. ( King, CA; Ogg, M, 2012) |
| "Data on the incidence of nosocomial infections before and after the introduction of propofol with EDTA indicates that there have been no further cluster outbreaks and individual nosocomial infections appear to have been reduced." | 2.43 | Propofol EDTA and reduced incidence of infection. ( Fukada, T; Jansson, JR; Kimura, S; Ozaki, M, 2006) |
| "Propofol was the most common adjunct agent, with dexmedetomidine and antipsychotics also used." | 1.42 | Multicenter evaluation of pharmacologic management and outcomes associated with severe resistant alcohol withdrawal. ( Benedict, NJ; Kane-Gill, SL; Wong, A, 2015) |
| "Postoperative complications were more frequent during the epidemic period than before it." | 1.29 | Postoperative infections traced to contamination of an intravenous anesthetic, propofol. ( Arduino, MJ; Bennett, SN; Bland, LA; Burwen, DR; McNeil, MM; Pegues, DA; Perrotta, DM; Stroud, L; Villarino, ME; Welbel, SF, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 5 (19.23) | 29.6817 |
| 2010's | 14 (53.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonilla-García, JL | 1 |
| Cortiñas-Sáenz, M | 1 |
| Pozo-Gavilán, ED | 1 |
| Cilli, F | 1 |
| Nazli-Zeka, A | 1 |
| Arda, B | 1 |
| Sipahi, OR | 1 |
| Aksit-Barik, S | 1 |
| Kepeli, N | 1 |
| Ozinel, MA | 1 |
| Gulay, Z | 1 |
| Ulusoy, S | 1 |
| García, JLB | 1 |
| Sáenz, MC | 1 |
| Gavilán, EDP | 1 |
| Cole, DC | 1 |
| Baslanti, TO | 1 |
| Gravenstein, NL | 1 |
| Gravenstein, N | 1 |
| Wong, A | 1 |
| Benedict, NJ | 1 |
| Kane-Gill, SL | 1 |
| Visvabharathy, L | 1 |
| Xayarath, B | 1 |
| Weinberg, G | 1 |
| Shilling, RA | 1 |
| Freitag, NE | 1 |
| Zorrilla-Vaca, A | 1 |
| Arevalo, JJ | 1 |
| Escandón-Vargas, K | 1 |
| Soltanifar, D | 1 |
| Mirski, MA | 1 |
| Caroff, DA | 1 |
| Szumita, PM | 1 |
| Klompas, M | 1 |
| Klein, J | 1 |
| Huisman, I | 1 |
| Menon, AG | 1 |
| Leenders, CM | 1 |
| van Eeghem, KH | 1 |
| Vos, MG | 1 |
| Dorresteijn, JJ | 1 |
| McAree, S | 1 |
| Radke, OC | 1 |
| Werth, K | 1 |
| Borg-von-Zepelin, M | 1 |
| Saur, P | 1 |
| Apfel, CC | 1 |
| Haddad, S | 1 |
| Tamim, H | 1 |
| Memish, ZA | 1 |
| Arabi, Y | 1 |
| King, CA | 1 |
| Ogg, M | 1 |
| Mathis, S | 1 |
| Tallis, GF | 1 |
| Ryan, GM | 1 |
| Lambert, SB | 1 |
| Bowden, DS | 1 |
| McCaw, R | 1 |
| Birch, CJ | 1 |
| Moloney, M | 1 |
| Carnie, JA | 1 |
| Locarnini, SA | 1 |
| Rouch, GJ | 1 |
| Catton, MG | 1 |
| Halkes, MJ | 1 |
| Snow, D | 1 |
| Jansson, JR | 1 |
| Fukada, T | 2 |
| Ozaki, M | 2 |
| Kimura, S | 1 |
| Bach, A | 2 |
| Geiss, HK | 1 |
| Grounds, RM | 1 |
| Kolbitsch, C | 1 |
| Lass-Flörl, C | 1 |
| Benzer, A | 1 |
| Bennett, SN | 1 |
| McNeil, MM | 1 |
| Bland, LA | 1 |
| Arduino, MJ | 1 |
| Villarino, ME | 1 |
| Perrotta, DM | 1 |
| Burwen, DR | 1 |
| Welbel, SF | 1 |
| Pegues, DA | 1 |
| Stroud, L | 1 |
| Nichols, RL | 1 |
| Smith, JW | 1 |
| Seeberger, MD | 1 |
| Staender, S | 1 |
| Oertli, D | 1 |
| Kindler, CH | 1 |
| Marti, W | 1 |
| Servais, H | 1 |
| Tulkens, PM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Bacterial and Fungal Contamination During Propofol Continuous Infusion in Patients Undergoing General Anesthesia[NCT00757458] | 652 participants (Anticipated) | Interventional | 2008-12-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for propofol and Health Care Associated Infection
| Article | Year |
|---|---|
Infectious Disease Risk Associated with Contaminated Propofol Anesthesia, 1989-2014(1).
Topics: Anesthetics, Intravenous; Communicable Diseases; Cross Infection; Disease Outbreaks; Drug Contaminat | 2016 |
The Relationship Between Sedatives, Sedative Strategy, and Healthcare-Associated Infection: A Systematic Review.
Topics: Animals; Benzodiazepines; Clinical Trials as Topic; Critical Care; Cross Infection; Disease Models, | 2016 |
Propofol EDTA and reduced incidence of infection.
Topics: Anesthetics, Intravenous; Anti-Infective Agents; Bacteria; Cross Infection; Drug Contamination; Edet | 2006 |
1 trial available for propofol and Health Care Associated Infection
| Article | Year |
|---|---|
Association of preservative-free propofol use and outcome in critically ill patients.
Topics: Cohort Studies; Critical Illness; Cross Infection; Dose-Response Relationship, Drug; Female; Hospita | 2011 |
22 other studies available for propofol and Health Care Associated Infection
| Article | Year |
|---|---|
Opioids and immunosupression in oncological postoperative patients.
Topics: Aged; Analgesics, Opioid; Cross Infection; Female; Humans; Immunosuppressive Agents; Male; Midazolam | 2017 |
Serratia marcescens sepsis outbreak caused by contaminated propofol.
Topics: Cross Infection; Disease Outbreaks; Drug Contamination; Electrophoresis, Gel, Pulsed-Field; Female; | 2019 |
Characterization of post-surgical critical patients with infections associated with healthcare after prolonged perfusion of remifentanil.
Topics: Aged; Analgesics, Opioid; Anesthesia, Local; APACHE; Critical Illness; Cross Infection; Deep Sedatio | 2018 |
Leaving more than your fingerprint on the intravenous line: a prospective study on propofol anesthesia and implications of stopcock contamination.
Topics: Administration, Intravenous; Anesthesia; Anesthesia, Intravenous; Anesthesiology; Central Venous Cat | 2015 |
Multicenter evaluation of pharmacologic management and outcomes associated with severe resistant alcohol withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Antipsychotic Agents; Benzodiazepin | 2015 |
Propofol Increases Host Susceptibility to Microbial Infection by Reducing Subpopulations of Mature Immune Effector Cells at Sites of Infection.
Topics: Animals; Animals, Outbred Strains; Bacterial Infections; Cell Count; Cells, Cultured; Cross Infectio | 2015 |
[Postoperative infection due to contaminated propofol].
Topics: Anesthetics, Intravenous; Cross Infection; Disease Outbreaks; Drug Contamination; Humans; Klebsiella | 2010 |
Ban on multidose vials. The proposal is misguided.
Topics: Anesthetics, Intravenous; Cross Infection; Drug Packaging; Humans; Propofol | 2010 |
Two serial check valves can prevent cross-contamination through intravenous tubing during total intravenous anesthesia.
Topics: Anesthesia, Intravenous; Cross Infection; Equipment Contamination; Infusions, Intravenous; Propofol; | 2010 |
Safe injection practices for administration of propofol.
Topics: Cross Infection; Disease Outbreaks; Drug Contamination; Equipment Reuse; Humans; Infection Control; | 2012 |
Closing in on health care-associated infections in the ambulatory surgical center.
Topics: Cluster Analysis; Communicable Disease Control; Cross Infection; Disease Notification; Disease Outbr | 2012 |
Evidence of patient-to-patient transmission of hepatitis C virus through contaminated intravenous anaesthetic ampoules.
Topics: Adult; Anesthetics, Intravenous; Arthroscopy; Cross Infection; Drug Packaging; Endoscopy; Equipment | 2003 |
Re-use of equipment between patients receiving total intravenous anaesthesia: a postal survey of current practice.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Clinical Competence; Cross Infection; Equipment R | 2003 |
Microbial growth in propofol formulations with disodium edetate and the influence of venous access system dead space.
Topics: Anesthetics, Intravenous; Bacteria; Chemistry, Pharmaceutical; Cross Infection; Drug Contamination; | 2007 |
Propofol and postoperative infections.
Topics: Anesthetics, Intravenous; Bacteria; Bacteriophage Typing; Cross Infection; Disease Outbreaks; Drug C | 1995 |
Propofol and postoperative infections.
Topics: Anesthesiology; Anesthetics, Intravenous; Asepsis; Cross Infection; Drug Contamination; Humans; Post | 1995 |
Propofol and postoperative infections.
Topics: Anesthesiology; Anesthetics, Intravenous; Asepsis; Bacteria; Cross Infection; Drug Contamination; Hu | 1995 |
Postoperative infections traced to contamination of an intravenous anesthetic, propofol.
Topics: Adult; Aged; Aged, 80 and over; Anesthesiology; Asepsis; Bacteria; Candida albicans; Case-Control St | 1995 |
Bacterial contamination of an anesthetic agent.
Topics: Anesthesiology; Asepsis; Cross Infection; Disease Outbreaks; Drug Contamination; Humans; Postoperati | 1995 |
Infections linked to anesthetic.
Topics: Anesthetics, Intravenous; Cross Infection; Drug Contamination; Humans; Infection Control; Postoperat | 1996 |
Efficacy of specific aseptic precautions for preventing propofol-related infections: analysis by a quality-assurance programme using the explicit outcome method.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Bacterial Infections; Cross Infection; Drug Co | 1998 |
Stability and compatibility of ceftazidime administered by continuous infusion to intensive care patients.
Topics: Ceftazidime; Cephalosporins; Critical Care; Cross Infection; Drug Incompatibility; Drug Stability; D | 2001 |