propofol has been researched along with Genetic Predisposition in 5 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inflated rates of opioid addiction among anesthesiologists may be caused by chronic exposure to low doses of aerosolized anesthetic/analgesic agents in the operating room." | 1.35 | Fentanyl and propofol exposure in the operating room: sensitization hypotheses and further data. ( Fitzgerald, K; Gold, MS; Goldberger, BA; Kolodner, D; Merlo, LJ, 2008) |
| " We conclude firstly that propofol is safe for individuals with predisposition to malignant hyperthermia when it is used within the recommended clinical dosage range, and secondly that its mode of action upon ryanodine receptors is likely to be different from that of caffeine." | 1.35 | Effects of propofol on calcium homeostasis in human skeletal muscle. ( Hamada, H; Kawamoto, M; Kobayashi, M; Migita, T; Mukaida, K; Nishino, I; Yuge, O, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, P | 1 |
| Sha, Z | 1 |
| Merlo, LJ | 1 |
| Goldberger, BA | 1 |
| Kolodner, D | 1 |
| Fitzgerald, K | 1 |
| Gold, MS | 1 |
| Migita, T | 1 |
| Mukaida, K | 1 |
| Hamada, H | 1 |
| Kobayashi, M | 1 |
| Nishino, I | 1 |
| Yuge, O | 1 |
| Kawamoto, M | 1 |
| Steinmetz, J | 1 |
| Jespersgaard, C | 1 |
| Dalhoff, K | 1 |
| Hedley, P | 1 |
| Abildstrøm, H | 1 |
| Christiansen, M | 1 |
| Rasmussen, LS | 1 |
| Wootton, MA | 1 |
| Lockie, J | 1 |
1 trial available for propofol and Genetic Predisposition
| Article | Year |
|---|---|
Cytochrome P450 polymorphism and postoperative cognitive dysfunction.
Topics: Aged; Aged, 80 and over; Alleles; Anesthetics, Intravenous; Aryl Hydrocarbon Hydroxylases; Biotransf | 2012 |
4 other studies available for propofol and Genetic Predisposition
| Article | Year |
|---|---|
Association of the lncRNA-GAS5 promoter region rs145204276 polymorphism with sevoflurane maintenance anesthesia outcomes on patients undergoing laparoscopic cholecystectomy.
Topics: Anesthesia; Cholecystectomy, Laparoscopic; Genetic Predisposition to Disease; Humans; Lipopolysaccha | 2023 |
Fentanyl and propofol exposure in the operating room: sensitization hypotheses and further data.
Topics: Air Pollutants, Occupational; Anesthesiology; Anesthetics, Intravenous; Dose-Response Relationship, | 2008 |
Effects of propofol on calcium homeostasis in human skeletal muscle.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Caffeine; Calcium; Child; Child, Preschool; Dose- | 2009 |
Anaesthetic management of a child with a positive family history of malignant hyperthermia for posterior fossa surgery in the sitting position.
Topics: Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Cerebellar Neoplasms; Child; Cranial | 2001 |