propofol has been researched along with Forearm Injuries in 2 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Forearm Injuries: Injuries to the part of the upper limb of the body between the wrist and elbow.
Excerpt | Relevance | Reference |
---|---|---|
"A case is presented of the use of a propofol infusion for anaesthesia in a patient with known variegate porphyria." | 7.67 | Is propofol a safe agent in porphyria? ( Hodkinson, BP; Weir, PM, 1988) |
"A case is presented of the use of a propofol infusion for anaesthesia in a patient with known variegate porphyria." | 3.67 | Is propofol a safe agent in porphyria? ( Hodkinson, BP; Weir, PM, 1988) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sharieff, GQ | 1 |
Trocinski, DR | 1 |
Kanegaye, JT | 1 |
Fisher, B | 1 |
Harley, JR | 1 |
Weir, PM | 1 |
Hodkinson, BP | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Comparison Between Efficacy of Ketamine and Propofol Mixture With 1:6 Ratio and 1:4 Ratio for Endoscopic Retrograde Procedure Sedation[NCT03196479] | 58 participants (Actual) | Interventional | 2017-03-01 | Completed | |||
Comparison of Ketamine Versus Co-Administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department[NCT01387139] | Phase 3 | 183 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
Combination Ketamine and Propofol vs Propofol for Emergency Department Sedation: A Prospective Randomized Trial[NCT01269307] | 99 participants (Actual) | Interventional | 2010-06-30 | Completed | |||
A Randomized Double-blind Trial to Evaluate Ketamine-propofol Combination vs. Propofol Alone for Procedural Sedation and Analgesia in the Emergency Department.[NCT01211158] | Phase 3 | 284 participants (Actual) | Interventional | 2010-12-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
"Efficacy is defined as:~The patient does not have unpleasant recall of the procedure.~The patient did not experience sedation-related adverse events resulting in abandonment of the procedure or a permanent complication or an unplanned admission to the hospital or prolonged emergency department (ED) observation~The patient did not actively resist or require physical restraint for completion of the procedure. The need for minimal redirection of movements should not be considered as active resistance or physical restraint.~The procedure was successful" (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | participants (Number) |
---|---|
Ketamine Alone | 97 |
Ketamine Co-Administered With Propofol | 81 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | units on a scale (Median) |
---|---|
Ketamine Alone | 10 |
Ketamine Co-Administered With Propofol | 8 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | units on a scale (1-10) (Median) |
---|---|
Ketamine Alone | 10 |
Ketamine Co-Administered With Propofol | 10 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | units on a scale (Median) |
---|---|
Ketamine Alone | 9 |
Ketamine Co-Administered With Propofol | 8 |
Time until the patient has a Vancouver Sedation Recovery Scale Score of 18 or greater. (NCT01387139)
Timeframe: Once Vancouver Sedation Recovery Scale Score reaches 18 or greater, on average less than 1 hour
Intervention | minutes (Median) |
---|---|
Ketamine Alone | 44 |
Ketamine Co-Administered With Propofol | 43.5 |
We will record all adverse events during the sedation, and then perform a follow-up call to determine if any additional adverse events occured after discharge. (NCT01387139)
Timeframe: From enrollment through completion of follow-up, up to 7 days
Intervention | participants (Number) | |||
---|---|---|---|---|
Respiratory depression | Cardiovascular event | vomiting/retching | Unpleasant recovery reaction | |
Ketamine Alone | 12 | 1 | 21 | 4 |
Ketamine Co-Administered With Propofol | 15 | 0 | 18 | 2 |
2 other studies available for propofol and Forearm Injuries
Article | Year |
---|---|
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Ketamine-propofol combination sedation for fracture reduction in the pediatric emergency department.
Topics: Adolescent; Anesthetics, Combined; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospit | 2007 |
Is propofol a safe agent in porphyria?
Topics: Adult; Anesthesia, Intravenous; Anesthetics; Forearm Injuries; Humans; Liver Diseases; Male; Phenols | 1988 |