propofol has been researched along with Esophagitis in 1 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Esophagitis: INFLAMMATION, acute or chronic, of the ESOPHAGUS caused by BACTERIA, chemicals, or TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol was administered via a target-controlled infusion system using the STANPUMP software based on a paediatric pharmacokinetic model." | 1.31 | Determination of the median effective concentration (EC50) of propofol during oesophagogastroduodenoscopy in children. ( Drover, DR; Hammer, GB; Litalien, C; Wellis, V, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hammer, GB | 1 |
| Litalien, C | 1 |
| Wellis, V | 1 |
| Drover, DR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sugammadex ED90 Dose to Reverse the Rocuronium Blockade in the Obese Patients[NCT02568345] | Phase 4 | 31 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| EEG to Monitor Propofol Anesthetic Depth in Infants and Toddlers[NCT05701748] | 120 participants (Anticipated) | Interventional | 2023-02-03 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Complete reversal of neuromuscular blockade occured when the patient had a TOF T4/T1 ≥ 0.9 within eight minutes of sugammadex infusion.~The sequencial design method of up-and-down was applied to determine the minimum effective dose in 90% of patients (ED90). An effective dose is one that achieves complete reversal of neuromuscular blockade that is defined as a measure of TOF equal or higher than 0.9, or a relationship between T4 an T1 measure ≥ 0.9, within eight minutes of sugammadex infusion." (NCT02568345)
Timeframe: 8 minutes
| Intervention | mg/kg (Number) |
|---|---|
| Sugammadex ED90 | 2.40 |
1 other study available for propofol and Esophagitis
| Article | Year |
|---|---|
Determination of the median effective concentration (EC50) of propofol during oesophagogastroduodenoscopy in children.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Child; Child, Preschool; Endoscopy, Gastrointesti | 2001 |
Determination of the median effective concentration (EC50) of propofol during oesophagogastroduodenoscopy in children.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Child; Child, Preschool; Endoscopy, Gastrointesti | 2001 |
Determination of the median effective concentration (EC50) of propofol during oesophagogastroduodenoscopy in children.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Child; Child, Preschool; Endoscopy, Gastrointesti | 2001 |
Determination of the median effective concentration (EC50) of propofol during oesophagogastroduodenoscopy in children.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Child; Child, Preschool; Endoscopy, Gastrointesti | 2001 |