Page last updated: 2024-11-03

propofol and Esophageal Varices

propofol has been researched along with Esophageal Varices in 8 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Propofol-based sedation exacerbated MHE after EIS similarly to midazolam-based sedation in patients with liver cirrhosis."9.27Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial. ( Hashimoto, M; Hikichi, T; Irie, H; Kikuchi, H; Konno, N; Nakamura, J; Obara, K; Ohira, H; Sato, Y; Sugimoto, M; Suzuki, R; Takagi, T; Takasumi, M; Watanabe, K, 2018)
"To investigate the efficacy and safety of a combination of sufentanil and propofol injection in patients undergoing endoscopic injection sclerotherapy (EIS) for esophageal varices (EVs)."9.24Role of combined propofol and sufentanil anesthesia in endoscopic injection sclerotherapy for esophageal varices. ( Qi, SL; Yu, Y; Zhang, Y, 2017)
"Midazolam sedation for upper gastrointestinal (GI) endoscopy exacerbates minimal hepatic encephalopathy (HE) in patients with liver cirrhosis, therefore an alternative drug regimen for these patients is warranted."9.14Propofol sedation for upper gastrointestinal endoscopy in patients with liver cirrhosis as an alternative to midazolam to avoid acute deterioration of minimal encephalopathy: a randomized, controlled study. ( Frenz, MB; Lechowicz, I; Riphaus, A; Wehrmann, T, 2009)
"Propofol-based sedation exacerbated MHE after EIS similarly to midazolam-based sedation in patients with liver cirrhosis."5.27Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial. ( Hashimoto, M; Hikichi, T; Irie, H; Kikuchi, H; Konno, N; Nakamura, J; Obara, K; Ohira, H; Sato, Y; Sugimoto, M; Suzuki, R; Takagi, T; Takasumi, M; Watanabe, K, 2018)
"To investigate the efficacy and safety of a combination of sufentanil and propofol injection in patients undergoing endoscopic injection sclerotherapy (EIS) for esophageal varices (EVs)."5.24Role of combined propofol and sufentanil anesthesia in endoscopic injection sclerotherapy for esophageal varices. ( Qi, SL; Yu, Y; Zhang, Y, 2017)
"Midazolam sedation for upper gastrointestinal (GI) endoscopy exacerbates minimal hepatic encephalopathy (HE) in patients with liver cirrhosis, therefore an alternative drug regimen for these patients is warranted."5.14Propofol sedation for upper gastrointestinal endoscopy in patients with liver cirrhosis as an alternative to midazolam to avoid acute deterioration of minimal encephalopathy: a randomized, controlled study. ( Frenz, MB; Lechowicz, I; Riphaus, A; Wehrmann, T, 2009)
"We aimed to investigate the safety of combined sedation with propofol plus fentanyl in patients with liver cirrhosis during screening esophagogastroduodenoscopy (SEGD) and a secondary prophylaxis for esophageal varices, endoscopic gastrointestinal ligation (EVL)."3.80The safety of combined sedation with propofol plus fentanyl for endoscopy screening and endoscopic variceal ligation in cirrhotic patients. ( Mao, W; Tao, J; Wei, XQ; Wen, ZF; Wu, B; Zhen, FP, 2014)
"Shock was more common in patients with variceal bleeding compared to those with non-variceal bleeding (12."1.43Outcomes of Propofol Sedation During Emergency Endoscopy Performed for Upper Gastrointestinal Bleeding. ( Eun, CS; Han, DS; Jeon, YC; Jeong, JY; Park, CH; Sohn, JH; Yoo, KS, 2016)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yu, Y1
Qi, SL1
Zhang, Y1
Trebicka, J1
Götz, M1
Watanabe, K1
Hikichi, T1
Takagi, T1
Suzuki, R1
Nakamura, J1
Sugimoto, M1
Kikuchi, H1
Konno, N1
Takasumi, M1
Sato, Y1
Hashimoto, M1
Irie, H1
Obara, K1
Ohira, H1
Mao, W1
Wei, XQ1
Tao, J1
Zhen, FP1
Wen, ZF1
Wu, B1
Park, CH1
Han, DS1
Jeong, JY1
Eun, CS1
Yoo, KS1
Jeon, YC1
Sohn, JH1
Riphaus, A1
Lechowicz, I1
Frenz, MB1
Wehrmann, T1
Weston, BR1
Chadalawada, V1
Chalasani, N1
Kwo, P1
Overley, CA1
Symms, M1
Strahl, E1
Rex, DK1
Abdmoulah, M1
Cayla, JM1
Valetoux, P1
Gouffier, E1

Trials

4 trials available for propofol and Esophageal Varices

ArticleYear
Role of combined propofol and sufentanil anesthesia in endoscopic injection sclerotherapy for esophageal varices.
    World journal of gastroenterology, 2017, Nov-28, Volume: 23, Issue:44

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia; Anesthetics, Intravenous; Esophageal and Gastric Varices

2017
Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial.
    Fukushima journal of medical science, 2018, Dec-08, Volume: 64, Issue:3

    Topics: Aged; Esophageal and Gastric Varices; Female; Hepatic Encephalopathy; Humans; Hypnotics and Sedative

2018
Propofol sedation for upper gastrointestinal endoscopy in patients with liver cirrhosis as an alternative to midazolam to avoid acute deterioration of minimal encephalopathy: a randomized, controlled study.
    Scandinavian journal of gastroenterology, 2009, Volume: 44, Issue:10

    Topics: Aged; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; Hepatic Encephalopathy; H

2009
Nurse-administered propofol versus midazolam and meperidine for upper endoscopy in cirrhotic patients.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:11

    Topics: Aged; Ambulatory Care; Chronic Disease; Conscious Sedation; Dose-Response Relationship, Drug; Drug A

2003

Other Studies

4 other studies available for propofol and Esophageal Varices

ArticleYear
[Gastrointestinal Bleeding: Update].
    Deutsche medizinische Wochenschrift (1946), 2018, Volume: 143, Issue:7

    Topics: Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Pr

2018
The safety of combined sedation with propofol plus fentanyl for endoscopy screening and endoscopic variceal ligation in cirrhotic patients.
    Journal of digestive diseases, 2014, Volume: 15, Issue:3

    Topics: Adult; Conscious Sedation; Drug Combinations; Endoscopy, Digestive System; Endoscopy, Gastrointestin

2014
Outcomes of Propofol Sedation During Emergency Endoscopy Performed for Upper Gastrointestinal Bleeding.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:3

    Topics: Adult; Age Factors; Aged; Anticoagulants; Cerebrovascular Disorders; Cohort Studies; Comorbidity; Di

2016
[Digestive hemorrhage caused by rupture of esophageal varices: emergency endoscopic sclerotherapy under general anesthesia].
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:3

    Topics: Adult; Aged; Anesthesia, General; Emergencies; Endoscopy, Gastrointestinal; Esophageal and Gastric V

1995