Page last updated: 2024-11-03

propofol and Epilepsy, Temporal Lobe

propofol has been researched along with Epilepsy, Temporal Lobe in 13 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).

Research Excerpts

ExcerptRelevanceReference
" Two animal models of TLE--amygdala kindling and pilocarpine-induced status epilepticus (Pilo-SE)--were tested."3.75Pilocarpine model of temporal lobe epilepsy shows enhanced response to general anesthetics. ( Leung, LS; Long, JJ; Luo, T; McMurran, TJ; Shen, B; Stewart, L, 2009)
"As amobarbital was no longer available, our aim was to validate propofol as an alternative."1.40Bilateral Wada test: amobarbital or propofol? ( Barragan-Jason, G; Busigny, T; Curot, J; Denuelle, M; Fabre, N; Kany, M; Marlat, F; Tall, P; Valton, L, 2014)
"Propofol was already used by Bazin et al."1.31The Wada test with propofol in a patient with epilepsy. ( Bueno, ML; Hernández-Fustes, OJ; Machado, S; Silva, TM; Varela, AM, 2000)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's3 (23.08)18.2507
2000's7 (53.85)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Curot, J1
Denuelle, M1
Busigny, T1
Barragan-Jason, G1
Kany, M1
Tall, P1
Marlat, F1
Fabre, N1
Valton, L1
Alsallom, FA1
Sinha, S1
Alsenani, FM1
Bamogaddam, FA1
Wahass, SH1
Canillo, AB1
Siddiqui, KA1
Long, JJ1
Shen, B1
Luo, T1
Stewart, L1
McMurran, TJ1
Leung, LS1
Fell, J1
Widman, G1
Rehberg, B1
Elger, CE1
Fernández, G1
Penide, C1
Penide, L1
Pumar, JM1
Pechstein, U2
Cedzich, C1
Nadstawek, J2
Schramm, J2
Zentner, J1
Silva, TM1
Hernández-Fustes, OJ1
Bueno, ML1
Varela, AM1
Machado, S1
Masters, LT1
Perrine, K1
Devinsky, O1
Nelson, PK1
Fukui, K1
Morioka, T1
Hisada, K1
Nishio, S1
Irita, K1
Takahashi, S1
Fukui, M1
Leijten, FS1
Teunissen, NW1
Wieneke, GH1
Knape, JT1
Schobben, AF1
van Huffelen, AC1
Silbergeld, DL1
Mueller, WM1
Colley, PS1
Ojemann, GA1
Lettich, E1
Hodkinson, BP1
Frith, RW1
Mee, EW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Dexmedetomidine and Propofol-Remifentanil Conscious Sedation for Awake Craniotomy for Tumor Surgery: a Randomized Controlled Trial[NCT01545297]50 participants (Actual)Interventional2012-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for propofol and Epilepsy, Temporal Lobe

ArticleYear
Human mediotemporal EEG characteristics during propofol anesthesia.
    Biological cybernetics, 2005, Volume: 92, Issue:2

    Topics: Adult; Anticonvulsants; Electrodes; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hippoca

2005
Isoflurane plus nitrous oxide versus propofol for recording of motor evoked potentials after high frequency repetitive electrical stimulation.
    Electroencephalography and clinical neurophysiology, 1998, Volume: 108, Issue:2

    Topics: Adolescent; Adult; Alfentanil; Anesthetics, Inhalation; Anesthetics, Intravenous; Cerebellar Neoplas

1998

Other Studies

11 other studies available for propofol and Epilepsy, Temporal Lobe

ArticleYear
Bilateral Wada test: amobarbital or propofol?
    Seizure, 2014, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Amobarbital; Anesthetics; Brain; Consciousness; Epilepsy, Temporal Lobe; Female;

2014
Tolerability of propofol in Wada testing.
    Neurosciences (Riyadh, Saudi Arabia), 2014, Volume: 19, Issue:3

    Topics: Adult; Anesthetics, Intravenous; Arabs; Brain Mapping; Electroencephalography; Epilepsy, Temporal Lo

2014
Pilocarpine model of temporal lobe epilepsy shows enhanced response to general anesthetics.
    Experimental neurology, 2009, Volume: 219, Issue:1

    Topics: Anesthetics, General; Animals; Brain; Consciousness Disorders; Convulsants; Disease Models, Animal;

2009
[Carotid artery infusion of propofol for the Wada test].
    Revista espanola de anestesiologia y reanimacion, 2007, Volume: 54, Issue:9

    Topics: Adult; Amobarbital; Anticonvulsants; Carotid Artery, Internal; Diagnostic Techniques, Neurological;

2007
Transcranial high-frequency repetitive electrical stimulation for recording myogenic motor evoked potentials with the patient under general anesthesia.
    Neurosurgery, 1996, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Alfentanil; Anesthesia, General; Brain Mapping; Child; Electric Stimulation; Epil

1996
The Wada test with propofol in a patient with epilepsy.
    Arquivos de neuro-psiquiatria, 2000, Volume: 58, Issue:2A

    Topics: Adult; Anesthetics, Intravenous; Epilepsy, Temporal Lobe; Female; Functional Laterality; Humans; Lan

2000
Wada testing in pediatric patients by use of propofol anesthesia.
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:7

    Topics: Adolescent; Amobarbital; Anesthesia, Intravenous; Child; Dominance, Cerebral; Epilepsy, Temporal Lob

2000
Ineffectiveness of propofol on intraoperative seizure activity in a patient with medial temporal lobe epilepsy.
    Journal of clinical anesthesia, 2000, Volume: 12, Issue:7

    Topics: Anticonvulsants; Child; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Intraoperative Comp

2000
Activation of interictal spiking in mesiotemporal lobe epilepsy by propofol-induced sleep.
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2001, Volume: 18, Issue:3

    Topics: Adult; Brain Mapping; Dominance, Cerebral; Dose-Response Relationship, Drug; Electroencephalography;

2001
Use of propofol (Diprivan) for awake craniotomies: technical note.
    Surgical neurology, 1992, Volume: 38, Issue:4

    Topics: Adolescent; Adult; Cerebral Cortex; Conscious Sedation; Craniotomy; Electroencephalography; Epilepsy

1992
Proprofol and the electroencephalogram.
    Lancet (London, England), 1987, Dec-26, Volume: 2, Issue:8574

    Topics: Anesthetics; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Phenols; Propofol

1987