propofol has been researched along with Elevated ICP (Intracranial Pressure) in 23 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol infusion syndrome (PRIS) is well known, often associated with, lethal complication of sedation with propofol." | 7.78 | Propofol infusion syndrome heralded by ECG changes. ( Aslan, A; Jacobs, B; Mijzen, EJ; Rodgers, MG, 2012) |
| " We studied the effects of indomethacin on ICP and cerebral blood flow (CBF) during isoflurane or propofol anesthesia in a sheep model of intracranial hypertension." | 7.73 | The effects of indomethacin on intracranial pressure and cerebral hemodynamics during isoflurane or propofol anesthesia in sheep with intracranial hypertension. ( Cold, GE; Grant, C; Ludbrook, G; Martinez, AM; Rasmussen, M; Upton, RN, 2006) |
| "Following the interesting reading of the article "A randomised trial to compare the increase in intracranial pressure as correlated with the optic nerve sheath diameter during propofol versus sevoflurane-maintained anesthesia in robot-assisted laparoscopic pelvic surgery", the authors comment some aspects about ocular ultrasonography to measure optic nerve sheath diameter as a tool to detect potential intracranial hypertension, pointing out the utility of Standardized A Scan technique for this purpose." | 3.91 | Ultrasound optic nerve sheath diameter evaluation in patients undergoing robot-assisted laparoscopic pelvic surgery. ( De Bernardo, M; Rosa, N; Vitiello, L, 2019) |
| "Propofol infusion syndrome (PRIS) is well known, often associated with, lethal complication of sedation with propofol." | 3.78 | Propofol infusion syndrome heralded by ECG changes. ( Aslan, A; Jacobs, B; Mijzen, EJ; Rodgers, MG, 2012) |
| " We studied the effects of indomethacin on ICP and cerebral blood flow (CBF) during isoflurane or propofol anesthesia in a sheep model of intracranial hypertension." | 3.73 | The effects of indomethacin on intracranial pressure and cerebral hemodynamics during isoflurane or propofol anesthesia in sheep with intracranial hypertension. ( Cold, GE; Grant, C; Ludbrook, G; Martinez, AM; Rasmussen, M; Upton, RN, 2006) |
| "Hydrocephalus is an active distension of the ventricular system of the brain." | 1.56 | Anaesthetic management of intracranial hypertension and pregnancy. A case report. ( Campos, MJ; Carreira, C; Norte, G; Órfão, R; Raimundo, A; Sampaio, A, 2020) |
| "The propofol infusion rate was non-significantly lower with drainage." | 1.38 | Effect of continuous cerebrospinal fluid drainage on therapeutic intensity in severe traumatic brain injury. ( Boch, AL; Boroli, F; Chauvet, D; Lescot, T; Puybasset, L; Reina, V, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 10 (43.48) | 29.6817 |
| 2010's | 10 (43.48) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Jeffcote, T | 1 |
| Weir, T | 1 |
| Anstey, J | 1 |
| Mcnamara, R | 1 |
| Bellomo, R | 1 |
| Udy, A | 1 |
| Sampaio, A | 1 |
| Norte, G | 1 |
| Campos, MJ | 1 |
| Raimundo, A | 1 |
| Carreira, C | 1 |
| Órfão, R | 1 |
| Sujata, N | 1 |
| Tobin, R | 1 |
| Tamhankar, A | 1 |
| Gautam, G | 1 |
| Yatoo, AH | 1 |
| Choi, ES | 1 |
| Jeon, YT | 1 |
| Sohn, HM | 1 |
| Kim, DW | 1 |
| Choi, SJ | 1 |
| In, CB | 1 |
| De Bernardo, M | 1 |
| Vitiello, L | 1 |
| Rosa, N | 1 |
| Dewhirst, E | 1 |
| Tobias, JD | 1 |
| Martin, DP | 1 |
| Colton, K | 2 |
| Yang, S | 2 |
| Hu, PF | 2 |
| Chen, HH | 2 |
| Bonds, B | 2 |
| Scalea, TM | 2 |
| Stein, DM | 2 |
| Stansbury, LG | 1 |
| Bader, MK | 1 |
| Vislosky, M | 1 |
| Gonçalves Dias, LG | 1 |
| Nunes, N | 1 |
| Lopes, PC | 1 |
| de Almeida, RM | 1 |
| Neto, GB | 1 |
| de Souza, AL | 1 |
| de Almeida Belmonte, E | 1 |
| Choi, HA | 1 |
| Ko, SB | 1 |
| Presciutti, M | 1 |
| Fernandez, L | 1 |
| Carpenter, AM | 1 |
| Lesch, C | 1 |
| Gilmore, E | 1 |
| Malhotra, R | 1 |
| Mayer, SA | 1 |
| Lee, K | 1 |
| Claassen, J | 1 |
| Schmidt, JM | 1 |
| Badjatia, N | 1 |
| Yu, G | 1 |
| Dymond, M | 1 |
| Yuan, L | 1 |
| Chaturvedi, LS | 1 |
| Shiratsuchi, H | 1 |
| Durairaj, S | 1 |
| Marsh, HM | 1 |
| Basson, MD | 1 |
| Lescot, T | 1 |
| Boroli, F | 1 |
| Reina, V | 1 |
| Chauvet, D | 1 |
| Boch, AL | 1 |
| Puybasset, L | 1 |
| Mijzen, EJ | 1 |
| Jacobs, B | 1 |
| Aslan, A | 1 |
| Rodgers, MG | 1 |
| Oertel, M | 1 |
| Kelly, DF | 1 |
| Lee, JH | 1 |
| Glenn, TC | 1 |
| Vespa, PM | 1 |
| Martin, NA | 1 |
| Holmström, A | 1 |
| Akeson, J | 1 |
| Cruz, J | 1 |
| Raghavan, M | 1 |
| Marik, PE | 1 |
| Rasmussen, M | 1 |
| Upton, RN | 1 |
| Grant, C | 1 |
| Martinez, AM | 1 |
| Cold, GE | 1 |
| Ludbrook, G | 1 |
| Corbett, SM | 1 |
| Moore, J | 1 |
| Rebuck, JA | 1 |
| Rogers, FB | 1 |
| Greene, CM | 1 |
| Ahlen, K | 1 |
| Buckley, C | 1 |
| Pulsford, AH | 1 |
| Hirota, K | 1 |
| Hashiba, E | 1 |
| Suzuki, A | 1 |
| Ishihara, H | 1 |
| Matsuki, A | 1 |
| Wijdicks, EF | 1 |
| Nyberg, SL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does the Choice of Administration Sequence of Propofol and Remifentanil Affect the ED50 and ED95 of Rocuronium for Rapid Sequence Induction of Anesthesia?[NCT02709473] | Phase 4 | 84 participants (Actual) | Interventional | 2016-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for propofol and Elevated ICP (Intracranial Pressure)
| Article | Year |
|---|---|
The Impact of Sedative Choice on Intracranial and Systemic Physiology in Moderate to Severe Traumatic Brain Injury: A Scoping Review.
Topics: Adult; Analgesics, Opioid; Brain Injuries; Brain Injuries, Traumatic; Dexmedetomidine; Humans; Hypno | 2023 |
Propofol and remifentanil for rapid sequence intubation in a pediatric patient at risk for aspiration with elevated intracranial pressure.
Topics: Anesthesia, Inhalation; Child; Contraindications; Deep Sedation; Emergencies; Headache; Humans; Hypn | 2013 |
Therapy of intracranial hypertension in patients with fulminant hepatic failure.
Topics: Ammonia; Anesthetics, Intravenous; Brain; Cardiovascular Agents; Cerebrovascular Circulation; Electr | 2006 |
3 trials available for propofol and Elevated ICP (Intracranial Pressure)
17 other studies available for propofol and Elevated ICP (Intracranial Pressure)
| Article | Year |
|---|---|
Anaesthetic management of intracranial hypertension and pregnancy. A case report.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia; Anesthetics, Inhalation; Cesarean Section; Female; Fentany | 2020 |
Ultrasound optic nerve sheath diameter evaluation in patients undergoing robot-assisted laparoscopic pelvic surgery.
Topics: Anesthesia; Anesthetics; Humans; Intracranial Hypertension; Intracranial Pressure; Intraoperative Co | 2019 |
Intracranial pressure response after pharmacologic treatment of intracranial hypertension.
Topics: Adult; Brain Injuries; Critical Care; Documentation; Female; Fentanyl; Humans; Hypnotics and Sedativ | 2014 |
Pharmacologic Treatment Reduces Pressure Times Time Dose and Relative Duration of Intracranial Hypertension.
Topics: Adult; Barbiturates; Brain Injuries; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Hyp | 2016 |
Tier approach to propofol infusion syndrome.
Topics: Anesthetics, Intravenous; Combined Modality Therapy; Critical Care; Drug Monitoring; Humans; Infusio | 2008 |
The effects of 2 levels of the inspired oxygen fraction on blood gas variables in propofol-anesthetized dogs with high intracranial pressure.
Topics: Anesthetics, Intravenous; Animals; Blood Gas Analysis; Cross-Over Studies; Dogs; Dose-Response Relat | 2009 |
Prevention of shivering during therapeutic temperature modulation: the Columbia anti-shivering protocol.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Anticonvulsants; Conscious Sedation; Critical Car | 2011 |
Propofol's effects on phagocytosis, proliferation, nitrate production, and cytokine secretion in pressure-stimulated microglial cells.
Topics: Anesthetics, Intravenous; Biological Assay; Brain Injuries; Cell Division; Cell Line; Cytokines; Hum | 2011 |
Effect of continuous cerebrospinal fluid drainage on therapeutic intensity in severe traumatic brain injury.
Topics: Adolescent; Adult; Aged; Blood Gas Analysis; Brain Injuries; Central Nervous System Infections; Cere | 2012 |
Propofol infusion syndrome heralded by ECG changes.
Topics: Acidosis; Brain Injuries; Electrocardiography; Humans; Hypnotics and Sedatives; Intracranial Hyperte | 2012 |
Metabolic suppressive therapy as a treatment for intracranial hypertension--why it works and when it fails.
Topics: Anticonvulsants; Biomarkers; Brain Injuries; Carbon Dioxide; Cerebrovascular Circulation; Humans; In | 2002 |
Cerebral blood flow at 0.5 and 1.0 minimal alveolar concentrations of desflurane or sevoflurane compared with isoflurane in normoventilated pigs.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Cerebrovascular Circ | 2003 |
Hyperventilation.
Topics: Adult; Blood Pressure; Brain Injuries; Female; Humans; Hyperventilation; Hypnotics and Sedatives; In | 2003 |
The effects of indomethacin on intracranial pressure and cerebral hemodynamics during isoflurane or propofol anesthesia in sheep with intracranial hypertension.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Pressure; | 2006 |
Survival of propofol infusion syndrome in a head-injured patient.
Topics: Acidosis, Lactic; Adult; Anesthetics, Intravenous; Brain Injuries; Drug Therapy, Combination; Humans | 2006 |
AstraZeneca's response to the review by Wysowski and Pollock regarding deaths reported in association with propofol use.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Drug Industry; Humans; Intracranial Hypert | 2007 |
Propofol to control intracranial pressure in fulminant hepatic failure.
Topics: Adolescent; Adult; Anticonvulsants; Female; Hepatic Encephalopathy; Humans; Intracranial Hypertensio | 2002 |