propofol has been researched along with Electrocardiogram QT Prolonged in 20 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a case of congenital long QT syndrome which developed torsade de pointes during sevoflurane anesthesia for implantation of an internal cardioverter-defibrillator." | 7.73 | Torsade de pointes during sevoflurane anesthesia in a child with congenital long QT syndrome. ( Davy, JM; Frapier, JM; Massad, I; Raczka, F; Saussine, M, 2006) |
| "This simulation study was designed to predict the torsadogenicity of sevoflurane and propofol in healthy control, as well as type 1 and type 2 long QT syndrome (LQT1 and LQT2, respectively), using the O'Hara-Rudy dynamic model." | 4.31 | Prediction of anesthetic torsadogenicity using a human ventricular cell model. ( Fukushima, Y; Kojima, A; Matsuura, H, 2023) |
| "We present a case of congenital long QT syndrome which developed torsade de pointes during sevoflurane anesthesia for implantation of an internal cardioverter-defibrillator." | 3.73 | Torsade de pointes during sevoflurane anesthesia in a child with congenital long QT syndrome. ( Davy, JM; Frapier, JM; Massad, I; Raczka, F; Saussine, M, 2006) |
| " Propofol was given to provide loss of consciousness during defibrillation shock administration, for induced ventricular fibrillation testing." | 3.70 | Idiopathic prolonged QT interval and QT dispersion: the effects of propofol during implantation of cardioverter-defibrillator. ( Flossos, A; Fraidakis, O; Kanoupakis, E; Manios, E; Michaloudis, D, 1999) |
| " Eight types of ECG-related adverse events were detected in 32 subjects." | 2.77 | [Effect of single doses of HX0507 on QTc intervals in healthy people: a phase I safety and tolerability study]. ( Li, R; Liao, TZ; Liu, J; Xu, J; Yi, XQ; Zhang, WS, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 10 (50.00) | 29.6817 |
| 2010's | 6 (30.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SH | 1 |
| Lee, JG | 1 |
| Ju, HM | 1 |
| Choi, S | 1 |
| Yang, H | 1 |
| Koo, BN | 1 |
| Kojima, A | 2 |
| Fukushima, Y | 2 |
| Matsuura, H | 2 |
| Itoh, H | 1 |
| Imoto, K | 1 |
| Görges, M | 1 |
| Whyte, SD | 2 |
| Sanatani, S | 1 |
| Dawes, J | 1 |
| Montgomery, CJ | 1 |
| Ansermino, JM | 1 |
| Chang, DJ | 1 |
| Kweon, TD | 2 |
| Nam, SB | 2 |
| Lee, JS | 2 |
| Shin, CS | 1 |
| Park, CH | 1 |
| Han, DW | 2 |
| Kim, DH | 1 |
| Cho, WY | 1 |
| Matsura, M | 1 |
| Fujiwara, Y | 1 |
| Ito, H | 1 |
| Kandatsu, N | 1 |
| Kato, N | 1 |
| Harada, J | 1 |
| Komatsu, T | 1 |
| Tezuka, N | 1 |
| Egawa, H | 1 |
| Fukagawa, D | 1 |
| Yamaguchi, S | 1 |
| Hamaguchi, S | 1 |
| Kitajima, T | 1 |
| Minami, J | 1 |
| Higashijima, U | 1 |
| Terao, Y | 1 |
| Ichinomiya, T | 1 |
| Miura, K | 1 |
| Fukusaki, M | 1 |
| Sumikawa, K | 1 |
| Mandal, B | 1 |
| Kaur, G | 1 |
| Batra, YK | 1 |
| Mahajan, S | 1 |
| Yi, XQ | 1 |
| Li, R | 1 |
| Zhang, WS | 1 |
| Liu, J | 1 |
| Xu, J | 1 |
| Liao, TZ | 1 |
| Michaloudis, D | 2 |
| Kanoupakis, E | 2 |
| Rewari, V | 1 |
| Kaul, H | 1 |
| Booker, PD | 1 |
| Buckley, DG | 1 |
| Yamada, M | 1 |
| Hatakeyama, N | 1 |
| Malykhina, AP | 1 |
| Yamazaki, M | 1 |
| Momose, Y | 1 |
| Akbarali, HI | 1 |
| Saussine, M | 1 |
| Massad, I | 1 |
| Raczka, F | 1 |
| Davy, JM | 1 |
| Frapier, JM | 1 |
| Pelter, MM | 1 |
| Carey, MG | 1 |
| Yu, JH | 1 |
| Hong, K | 1 |
| Cheng, KC | 1 |
| Fraidakis, O | 1 |
| Flossos, A | 1 |
| Manios, E | 1 |
| Kleinsasser, A | 1 |
| Loeckinger, A | 1 |
| Lindner, KH | 1 |
| Keller, C | 1 |
| Boehler, M | 1 |
| Puehringer, F | 1 |
8 trials available for propofol and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Propofol prevents further prolongation of QT interval during liver transplantation.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Desflurane; Humans; Liver Transplantation; Living | 2022 |
Effects of fentanyl pretreatment on the QTc interval during propofol induction.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Double-Blind Method; Elect | 2008 |
Effects of target concentration infusion of propofol and tracheal intubation on QTc interval.
Topics: Adult; Anesthetics, Intravenous; Blood Pressure; Heart Rate; Humans; Infusions, Intravenous; Intubat | 2008 |
Prolongation of QT interval induced by electroconvulsive therapy is attenuated by landiolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Anti-Ar | 2010 |
A comparison of the effect on QT interval between thiamylal and propofol during anaesthetic induction*.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Blood Pressure; Electrocardiography; Femal | 2010 |
[Effect of single doses of HX0507 on QTc intervals in healthy people: a phase I safety and tolerability study].
Topics: Adolescent; Adult; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Middle Aged; Prodrug | 2012 |
The effects of propofol and sevoflurane on the QT interval and transmural dispersion of repolarization in children.
Topics: Adolescent; Anesthesia, General; Anesthetics, Intravenous; Child; Child, Preschool; Electrocardiogra | 2005 |
Reversing sevoflurane-associated Q-Tc prolongation by changing to propofol.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Electrocardiography; | 2001 |
12 other studies available for propofol and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Prediction of anesthetic torsadogenicity using a human ventricular cell model.
Topics: Action Potentials; Anesthetics; Humans; Long QT Syndrome; Propofol; Sevoflurane | 2023 |
A computational analysis of the effect of sevoflurane in a human ventricular cell model of long QT syndrome: Importance of repolarization reserve in the QT-prolonging effect of sevoflurane.
Topics: Action Potentials; Case-Control Studies; Computer Simulation; Delayed Rectifier Potassium Channels; | 2020 |
Changes in QTc associated with a rapid bolus dose of dexmedetomidine in patients receiving TIVA: a retrospective study.
Topics: Administration, Intravenous; Anesthesia, Intravenous; Anesthetics, Intravenous; Child; Child, Presch | 2015 |
Assessment of QT interval and QT dispersion during electroconvulsive therapy using computerized measurements.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Computers; Electrocardiography; Electrocon | 2010 |
Manifestation of Long QT syndrome with normal QTc interval under anesthesia: a case report.
Topics: Adrenergic alpha-Agonists; Anesthesia; Anti-Arrhythmia Agents; Atracurium; Atropine; Cardiopulmonary | 2011 |
Propofol reduces idiopathic prolonged QT interval and QT dispersion during implantation of cardioverter defibrillator.
Topics: Anesthetics, Intravenous; Defibrillators, Implantable; Electrocardiography; Humans; Long QT Syndrome | 2003 |
Sustained ventricular tachycardia in long QT syndrome: is propofol the culprit?
Topics: Anesthetics, Inhalation; Electrocardiography; Humans; Intraoperative Complications; Long QT Syndrome | 2003 |
The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a-go-go related gene currents in Xenopus oocytes.
Topics: Animals; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Female; Gene Expression | 2006 |
Torsade de pointes during sevoflurane anesthesia in a child with congenital long QT syndrome.
Topics: Anesthetics, Inhalation; Anticonvulsants; Child; Defibrillators, Implantable; Electrocardiography; H | 2006 |
Long QT syndrome.
Topics: Aged; Anesthetics, Intravenous; Electrocardiography; Female; Humans; Intubation, Intratracheal; Long | 2006 |
[Propofol associated with hypokalemia causes electro storm].
Topics: Adolescent; Anesthesia; Electrocardiography; Humans; Hypokalemia; Long QT Syndrome; Male; Propofol; | 2007 |
Idiopathic prolonged QT interval and QT dispersion: the effects of propofol during implantation of cardioverter-defibrillator.
Topics: Adult; Anesthesia, Local; Anesthetics, Intravenous; Blood Pressure; Cardiac Pacing, Artificial; Cons | 1999 |