Page last updated: 2024-11-03

propofol and Dystonia

propofol has been researched along with Dystonia in 17 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)

Research Excerpts

ExcerptRelevanceReference
"To report a case of refractory dystonia under propofol anaesthesia in a patient with Torticollis-Dystonia disorder."7.69Refractory dystonia during propofol anaesthesia in a patient with torticollis-dystonia disorder. ( Vaghadia, H; Zabani, I, 1996)
"Acute, severe dystonia is a frightening and potentially life-threatening surgical complication."5.56Acute, severe dystonia after strabismus surgery in a patient on propofol, ondansetron, and bupropion. ( Dagi, LR; Elhusseiny, AM; Grush, A, 2020)
"To report a case of refractory dystonia under propofol anaesthesia in a patient with Torticollis-Dystonia disorder."3.69Refractory dystonia during propofol anaesthesia in a patient with torticollis-dystonia disorder. ( Vaghadia, H; Zabani, I, 1996)
"Excitatory effects, including myoclonus, tremor, and dystonic posturing, occurred in 86."2.67Excitatory effects and electroencephalographic correlation of etomidate, thiopental, methohexital, and propofol. ( Deitch, RD; Dierdorf, SF; Link, L; Moorthy, SS; Reddy, RV, 1993)
"The true incidence of seizures caused by general anesthetic drugs is unknown."2.44The howling cortex: seizures and general anesthetic drugs. ( Barnard, JP; Kirsch, HE; Sleigh, JW; Voss, LJ, 2008)
"Acute, severe dystonia is a frightening and potentially life-threatening surgical complication."1.56Acute, severe dystonia after strabismus surgery in a patient on propofol, ondansetron, and bupropion. ( Dagi, LR; Elhusseiny, AM; Grush, A, 2020)
"Low-dose propofol in one other dystonia patient also seemed to suppress GPi firing."1.32Pallidal neuronal activity: implications for models of dystonia. ( Dostrovsky, JO; Hutchison, WD; Lang, AE; Lozano, AM, 2003)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (23.53)18.2507
2000's7 (41.18)29.6817
2010's5 (29.41)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Elhusseiny, AM1
Grush, A1
Dagi, LR1
Mitek, AE1
Clark-Price, SC1
Boesch, JM1
Castrioto, A1
Marmor, O1
Deffains, M1
Willner, D1
Linetsky, E1
Bergman, H1
Israel, Z1
Eitan, R1
Arkadir, D1
Voss, LJ1
Sleigh, JW1
Barnard, JP1
Kirsch, HE1
Papaioannou, A1
Mathioudakis, E1
Nyktari, V1
Astyrakaki, E1
Sgourou, K1
Askitopoulou, H1
Cosentino, C1
Torres, L1
Size, MH1
Rubin, JS1
Patel, A1
Hutchison, WD2
Lang, AE2
Dostrovsky, JO2
Lozano, AM2
Pralong, E1
Debatisse, D1
Maeder, M1
Vingerhoets, F1
Ghika, J1
Villemure, JG1
Saravanakumar, K1
Venkatesh, P1
Bromley, P1
Fleming, JA1
Reddy, RV1
Moorthy, SS1
Dierdorf, SF1
Deitch, RD1
Link, L1
Zabani, I1
Vaghadia, H1
Kumar, R1
Gross, RE1
Giladi, N1
Bragonier, R1
Bartle, D1
Langton-Hewer, S1
Ananthanarayan, C1
Blight, K1
Schramm, BM1
Orser, BA1

Reviews

2 reviews available for propofol and Dystonia

ArticleYear
The howling cortex: seizures and general anesthetic drugs.
    Anesthesia and analgesia, 2008, Volume: 107, Issue:5

    Topics: Anesthesia; Anesthetics, General; Animals; Dystonia; Electroencephalography; Epilepsy; Humans; Ketam

2008
Dystonic reaction to propofol attenuated by benztropine (cogentin).
    Anesthesia and analgesia, 2002, Volume: 94, Issue:5

    Topics: Anesthetics, Intravenous; Benztropine; Dystonia; Humans; Male; Middle Aged; Muscarinic Antagonists;

2002

Trials

1 trial available for propofol and Dystonia

ArticleYear
Excitatory effects and electroencephalographic correlation of etomidate, thiopental, methohexital, and propofol.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:5

    Topics: Aged; Aged, 80 and over; Anesthesia, Intravenous; Dystonia; Electroencephalography; Etomidate; Human

1993

Other Studies

14 other studies available for propofol and Dystonia

ArticleYear
Acute, severe dystonia after strabismus surgery in a patient on propofol, ondansetron, and bupropion.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2020, Volume: 24, Issue:5

    Topics: Adult; Antiemetics; Bupropion; Double-Blind Method; Dystonia; Female; Humans; Ondansetron; Propofol;

2020
Severe propofol-associated dystonia in a dog.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2013, Volume: 54, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Dog Diseases; Dogs; Dystonia; Hypnotics and Sedatives; Isoflurane;

2013
Anesthesia reduces discharge rates in the human pallidum without changing the discharge rate ratio between pallidal segments.
    The European journal of neuroscience, 2016, Volume: 44, Issue:11

    Topics: Action Potentials; Adult; Anesthetics, Intravenous; Case-Control Studies; Deep Brain Stimulation; Dy

2016
Does propofol induction in patients on olanzapine increase the susceptibility to dystonic reactions?
    Acta anaesthesiologica Scandinavica, 2011, Volume: 55, Issue:5

    Topics: Adult; Airway Obstruction; Anesthetics, Intravenous; Antipsychotic Agents; Benzodiazepines; Drug Int

2011
Propofol-induced paroxysmal dystonia.
    Parkinsonism & related disorders, 2012, Volume: 18, Issue:2

    Topics: Adult; Dystonia; Female; Humans; Propofol

2012
Acute dystonic reaction to general anesthesia with propofol and ondansetron: a graded response.
    Ear, nose, & throat journal, 2013, Volume: 92, Issue:1

    Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Antiemetics; Dystonia; Female; Humans; Ondanse

2013
Pallidal neuronal activity: implications for models of dystonia.
    Annals of neurology, 2003, Volume: 53, Issue:4

    Topics: Adolescent; Adult; Anticonvulsants; Child; Dystonia; Electromyography; Globus Pallidus; Humans; Micr

2003
Effect of deep brain stimulation of GPI on neuronal activity of the thalamic nucleus ventralis oralis in a dystonic patient.
    Neurophysiologie clinique = Clinical neurophysiology, 2003, Volume: 33, Issue:4

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Dystonia; Electric Stimulation; Electrodes

2003
Delayed onset refractory dystonic movements following propofol anesthesia.
    Paediatric anaesthesia, 2005, Volume: 15, Issue:7

    Topics: Adolescent; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, I

2005
Propofol--rational and accurate reporting.
    Anaesthesia and intensive care, 1993, Volume: 21, Issue:6

    Topics: Australia; Dystonia; Epilepsy; Humans; Muscle Hypertonia; Muscle Tonus; Product Surveillance, Postma

1993
Refractory dystonia during propofol anaesthesia in a patient with torticollis-dystonia disorder.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1996, Volume: 43, Issue:10

    Topics: Adult; Anesthetics, Intravenous; Dystonia; Humans; Male; Propofol; Torticollis

1996
Globus pallidus internus pallidotomy for generalized dystonia.
    Movement disorders : official journal of the Movement Disorder Society, 1997, Volume: 12, Issue:6

    Topics: Anesthesia, General; Anesthetics, General; Child; Dystonia; Globus Pallidus; Humans; Magnetic Resona

1997
Acute dystonia in a 14-yr-old following propofol and fentanyl anaesthesia.
    British journal of anaesthesia, 2000, Volume: 84, Issue:6

    Topics: Acute Disease; Adolescent; Anesthetics, Combined; Anesthetics, Intravenous; Dystonia; Female; Fentan

2000
Dystonic reaction after anesthesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2001, Volume: 48, Issue:1

    Topics: Adult; Anesthesia; Anesthetics, Intravenous; Antiemetics; Dystonia; Female; Humans; Ondansetron; Pro

2001