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propofol and Drug Hypersensitivity

propofol has been researched along with Drug Hypersensitivity in 37 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.

Research Excerpts

ExcerptRelevanceReference
"Pulmonary edema after the administration of propofol has rarely been reported."7.74Late-onset pulmonary edema due to propofol. ( Cakir, U; Inal, MT; Memis, D; Vatan, I; Yildiz, B, 2008)
"To report a case of anaphylaxis due to propofol in a child with allergies to egg and peanut oil."7.72Possible anaphylaxis after propofol in a child with food allergy. ( Buck, ML; Hendrick, AE; Hofer, KN; McCarthy, MW, 2003)
"Propofol was safely administered for procedural sedation in a large series of adult EoE patients multisensitized to egg, soy, peanut, showing one-third clinical allergy to these foods."5.40Propofol administration is safe in adult eosinophilic esophagitis patients sensitized to egg, soy, or peanut. ( Alvarado-Arenas, M; Arias, A; Gonzalez-Cervera, J; Lucendo, AJ; Molina-Infante, J; Prados-Manzano, R; Vara-Brenes, D, 2014)
"Pulmonary edema after the administration of propofol has rarely been reported."3.74Late-onset pulmonary edema due to propofol. ( Cakir, U; Inal, MT; Memis, D; Vatan, I; Yildiz, B, 2008)
"To report a case of anaphylaxis due to propofol in a child with allergies to egg and peanut oil."3.72Possible anaphylaxis after propofol in a child with food allergy. ( Buck, ML; Hendrick, AE; Hofer, KN; McCarthy, MW, 2003)
" Better understanding of of this cross-reactivity is important to providing safe care."2.53Is Propofol Safe For Food Allergy Patients? A Review of the Evidence. ( Dziedzic, A, 2016)
"Of these, 201 (66%) had an egg allergy, 226 (74%) had a peanut allergy, 28 (9%) had a soybean allergy and 12 (4%) had a legume allergy."1.51Propofol use in children with allergies to egg, peanut, soybean or other legumes. ( Arnold, A; Drake-Brockman, TFE; Lucas, M; Schilling, A; Sommerfield, A; Sommerfield, DL; von Ungern-Sternberg, BS, 2019)
"Propofol is thought to be a potential cause of allergic reactions in patients allergic to egg, soy or peanut, since current formulations contain an emulsion that includes egg lecithin and soybean oil."1.43No evidence for contraindications to the use of propofol in adults allergic to egg, soy or peanut†. ( Asserhøj, LL; Garvey, LH; Krøigaard, M; Mosbech, H, 2016)
"Propofol was safely administered for procedural sedation in a large series of adult EoE patients multisensitized to egg, soy, peanut, showing one-third clinical allergy to these foods."1.40Propofol administration is safe in adult eosinophilic esophagitis patients sensitized to egg, soy, or peanut. ( Alvarado-Arenas, M; Arias, A; Gonzalez-Cervera, J; Lucendo, AJ; Molina-Infante, J; Prados-Manzano, R; Vara-Brenes, D, 2014)
"The study describes a delayed hypersensitivity to suxamethonium, driven by an oligoclonal T helper cell 1-skewed CD4+ memory T cell population, expressing the skin homing receptors CLA and CCR4."1.33Delayed allergic reaction to suxamethonium driven by oligoclonal Th1-skewed CD4+CCR4+IFN-gamma+ memory T cells. ( Giani, M; Guerra, EC; Locanto, M; Mari, A; Mondino, C; Pirrotta, L; Scala, E, 2006)
" Using the patient's response to a large-dose fentanyl infusion in conjunction with a pharmacokinetic simulation, effective intraoperative and postoperative fentanyl plasma concentrations were achieved."1.32Preoperative fentanyl infusion with pharmacokinetic simulation for anesthetic and perioperative management of an opioid-tolerant patient. ( Davis, JJ; Egan, TD; Johnson, KB; Snell, TE; Swenson, JD; Vezina, DP, 2003)
"Histamine was measured by radio-immunology (Immunotech)."1.27[Non-specific histamine liberation and propofol]. ( Bois, JP; Heravi, Z; Khamel, L; Laxenaire, MC; Manel, J, 1987)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19907 (18.92)18.7374
1990's7 (18.92)18.2507
2000's7 (18.92)29.6817
2010's14 (37.84)24.3611
2020's2 (5.41)2.80

Authors

AuthorsStudies
Ho, NT1
Bradbrook, CA1
Kanda, H1
Kamiya, H1
Sugawara, A1
Yamaya, S1
Onodera, Y1
Toyama, Y1
Kunisawa, T1
Tornero Molina, P1
Rojas-Perez-Ezquerra, P1
Noguerado-Mellado, B1
Baeza Ochoa de Ocáriz, ML1
Garrido Sánchez, A1
Alonso Mateos, M1
Zubeldia Ortuño, JM1
Sommerfield, DL1
Lucas, M1
Schilling, A1
Drake-Brockman, TFE1
Sommerfield, A1
Arnold, A1
von Ungern-Sternberg, BS1
Molina-Infante, J1
Arias, A1
Vara-Brenes, D1
Prados-Manzano, R1
Gonzalez-Cervera, J1
Alvarado-Arenas, M1
Lucendo, AJ1
Harper, NJ1
Asserhøj, LL1
Mosbech, H2
Krøigaard, M2
Garvey, LH2
Dziedzic, A1
Kuric, V1
Zaza, KJ1
Algazlan, SS1
Forshaw, N1
Smith, J1
Romero Palomino, P1
Gerónimo Pardo, M1
Sánchez Sánchez, I1
Villar Cánovas, MT1
Fontaine, M1
Dubost, J1
Bienvenu, F1
Ferrenq Dubost, R1
Proton, G1
Piriou, V1
Murphy, A1
Campbell, DE1
Baines, D1
Mehr, S1
Dewachter, P1
Mouton-Faivre, C1
Castells, MC1
Hepner, DL1
Audicana Berasategui, MT1
Barasona Villarejo, MJ1
Corominas Sánchez, M1
De Barrio Fernández, M1
García Avilés, MC1
García Robaina, JC1
Gastaminza Lasarte, G1
Laguna Martínez, JJ1
Lobera Labairu, T1
López San Martín, M1
Martín Lázaro, J1
Moreno Rodilla, E1
Ortega Rodríguez, N1
Torres Jaén, MJ1
Blichfeldt, L1
Cochico, SG1
Hofer, KN1
McCarthy, MW1
Buck, ML1
Hendrick, AE1
Davis, JJ1
Johnson, KB1
Egan, TD1
Vezina, DP1
Snell, TE1
Swenson, JD1
Ackland, GL1
Fox, R1
Scala, E1
Guerra, EC1
Giani, M1
Pirrotta, L1
Locanto, M1
Mondino, C1
Mari, A1
McNeill, O1
Kerridge, RK1
Boyle, MJ1
Inal, MT1
Memis, D1
Vatan, I1
Cakir, U1
Yildiz, B1
Clarke, RS2
Briggs, LP1
Watkins, J1
Doenicke, A1
Couldwell, WT1
Giannotta, SL1
Zelman, V1
DeGiorgio, CM1
Guéant, JL2
Mata, E1
Masson, C1
Moneret-Vautrin, DA1
Laxenaire, MC3
Hassoun, S1
Sabbah, A1
Drouet, M1
Cottineau, C1
Sneyd, JR1
Langevin, PB1
Williamson, J1
Khamel, L1
Heravi, Z1
Manel, J2
Bois, JP1
Widmer, S1
Kumar, CM1
McNeela, BJ1
Naquib, M1
Dold, M1
Konarzewski, WH1

Reviews

3 reviews available for propofol and Drug Hypersensitivity

ArticleYear
Is Propofol Safe For Food Allergy Patients? A Review of the Evidence.
    SAAD digest, 2016, Volume: 32

    Topics: Anesthetics, Intravenous; Contraindications; Cross Reactions; Drug Hypersensitivity; Food Hypersensi

2016
Anesthesia in the patient with multiple drug allergies: are all allergies the same?
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:3

    Topics: Analgesics; Anaphylaxis; Anesthesia; Anesthetics; Anesthetics, Intravenous; Animals; Anti-Bacterial

2011
Potential hypersensitivity due to the food or food additive content of medicinal products in Spain.
    Journal of investigational allergology & clinical immunology, 2011, Volume: 21, Issue:7

    Topics: Drug Hypersensitivity; Food Additives; Food Hypersensitivity; Glucosamine; Humans; Lactose; Muramida

2011

Other Studies

34 other studies available for propofol and Drug Hypersensitivity

ArticleYear
Suspected allergic reaction following use of propofol for induction of anaesthesia.
    Veterinary anaesthesia and analgesia, 2020, Volume: 47, Issue:4

    Topics: Anesthetics, Intravenous; Animals; Dog Diseases; Dogs; Drug Hypersensitivity; Female; Propofol

2020
Minimally Invasive Awake Mitral Valve Surgery and Cardiopulmonary Bypass Without General Anesthesia.
    The Annals of thoracic surgery, 2019, Volume: 107, Issue:4

    Topics: Anesthesia, Epidural; Cardiopulmonary Bypass; Drug Hypersensitivity; Follow-Up Studies; Heart Valve

2019
Drug Challenge Tests With General Anesthetics: Predictive Value of Skin Tests.
    Journal of investigational allergology & clinical immunology, 2020, Apr-24, Volume: 30, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, General; Anesthetics, Intravenous;

2020
Propofol use in children with allergies to egg, peanut, soybean or other legumes.
    Anaesthesia, 2019, Volume: 74, Issue:10

    Topics: Adolescent; Anesthesia, General; Anesthetics, Intravenous; Child; Child, Preschool; Drug Hypersensit

2019
Propofol administration is safe in adult eosinophilic esophagitis patients sensitized to egg, soy, or peanut.
    Allergy, 2014, Volume: 69, Issue:3

    Topics: Adolescent; Adult; Arachis; Drug Hypersensitivity; Eggs; Eosinophilic Esophagitis; Female; Food; Foo

2014
Propofol and food allergy.
    British journal of anaesthesia, 2016, Volume: 116, Issue:1

    Topics: Adult; Anesthetics, Intravenous; Child; Drug Hypersensitivity; Food Hypersensitivity; Humans; Propof

2016
No evidence for contraindications to the use of propofol in adults allergic to egg, soy or peanut†.
    British journal of anaesthesia, 2016, Volume: 116, Issue:1

    Topics: Adult; Anesthesia, Intravenous; Drug Hypersensitivity; Egg Hypersensitivity; Female; Food Hypersensi

2016
Atypical presentation to rocuronium allergy in a 19-year-old female patient.
    Journal of clinical anesthesia, 2017, Volume: 37

    Topics: Adult; Anaphylaxis; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Cardiopulmonary Res

2017
Is propofol safe to use in children with food allergies?
    British journal of hospital medicine (London, England : 2005), 2017, Mar-02, Volume: 78, Issue:3

    Topics: Anaphylaxis; Anesthetics, Intravenous; Child; Cross Reactions; Drug Hypersensitivity; Food Hypersens

2017
[Lumbar spine arthrodesis under general anesthesia in a patient allergic to fentanyl].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:1

    Topics: Aged; Amides; Analgesia, Epidural; Analgesics, Non-Narcotic; Androstanols; Anesthesia, General; Anes

2009
[Severe bronchospasm using Diprivan® in a patient allergic to peanut and birch].
    Annales francaises d'anesthesie et de reanimation, 2011, Volume: 30, Issue:2

    Topics: Anesthesia, General; Asthma; Betula; Bronchial Spasm; Child; Drug Hypersensitivity; Humans; Hypnotic

2011
Allergic reactions to propofol in egg-allergic children.
    Anesthesia and analgesia, 2011, Volume: 113, Issue:1

    Topics: Adolescent; Anaphylaxis; Child; Child, Preschool; Drug Hypersensitivity; Egg Hypersensitivity; Egg W

2011
[Suspected allergic reaction during anesthesia requires thorough postoperative investigation].
    Ugeskrift for laeger, 2012, Feb-27, Volume: 174, Issue:9

    Topics: Analgesics, Opioid; Anesthetics, Intravenous; Drug Hypersensitivity; Female; Fentanyl; Histamine Rel

2012
Propofol allergy: assessing for patient risks.
    AORN journal, 2012, Volume: 96, Issue:4

    Topics: Anaphylaxis; Contraindications; Drug Hypersensitivity; Food Hypersensitivity; Humans; Hypnotics and

2012
Possible anaphylaxis after propofol in a child with food allergy.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:3

    Topics: Anaphylaxis; Child, Preschool; Drug Hypersensitivity; Drug Interactions; Egg Hypersensitivity; Human

2003
Preoperative fentanyl infusion with pharmacokinetic simulation for anesthetic and perioperative management of an opioid-tolerant patient.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:6

    Topics: Analgesics, Opioid; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Benzodiazepines;

2003
Low-dose propofol infusion for controlling acute hyperspasticity after withdrawal of intrathecal baclofen therapy.
    Anesthesiology, 2005, Volume: 103, Issue:3

    Topics: Acute Disease; Adult; Aged; Baclofen; Drug Hypersensitivity; Humans; Injections, Spinal; Male; Muscl

2005
Delayed allergic reaction to suxamethonium driven by oligoclonal Th1-skewed CD4+CCR4+IFN-gamma+ memory T cells.
    International archives of allergy and immunology, 2006, Volume: 141, Issue:1

    Topics: Adjuvants, Anesthesia; Aged; Anesthetics, Intravenous; Atropine; CD4 Antigens; Clone Cells; Drug Hyp

2006
Review of procedures for investigation of anaesthesia-associated anaphylaxis in Newcastle, Australia.
    Anaesthesia and intensive care, 2008, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anaphylaxis; Anesthesia, General; Anesthetics; Anestheti

2008
Late-onset pulmonary edema due to propofol.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7

    Topics: Adult; Anesthetics, Intravenous; Blood Gas Analysis; Blood Pressure; Cesarean Section; Critical Care

2008
Comparative merits of intravenous anesthetic agents for outpatient surgery.
    International anesthesiology clinics, 1982,Spring, Volume: 20, Issue:1

    Topics: Alfaxalone Alfadolone Mixture; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Anesthetics;

1982
An adverse reaction to the administration of disoprofol (Diprivan).
    Anaesthesia, 1982, Volume: 37, Issue:11

    Topics: Adult; Anaphylaxis; Anesthesia, Intravenous; Anesthetics; Drug Hypersensitivity; Female; Humans; Phe

1982
Is Atracurium contraindicated in patients with a known allergy to drugs?
    Anesthesiology, 1993, Volume: 78, Issue:3

    Topics: Anaphylaxis; Atracurium; Contraindications; Drug Hypersensitivity; Histamine Release; Humans; Propof

1993
Life-threatening reactions to propofol.
    Neurosurgery, 1993, Volume: 33, Issue:6

    Topics: Adult; Drug Carriers; Drug Hypersensitivity; Emulsions; Female; Humans; Intraoperative Complications

1993
Non specific interactions in anti-agent IgE-RIA to anesthetic agents.
    Annales francaises d'anesthesie et de reanimation, 1993, Volume: 12, Issue:2

    Topics: Antibodies, Anti-Idiotypic; Cross Reactions; Drug Hypersensitivity; Drug Interactions; Humans; Immun

1993
[Predictive value of the allergologic profile in anesthesia and resuscitation].
    Allergie et immunologie, 1998, Volume: 30, Issue:6

    Topics: Adolescent; Adult; Aged; Anaphylaxis; Anesthetics; Anesthetics, Intravenous; Bronchial Spasm; Child;

1998
Catecholamine-resistant cardiovascular collapse after propofol, atracurium and gentamicin.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:5

    Topics: Adrenergic alpha-Agonists; Adult; Anesthetics, Intravenous; Anti-Bacterial Agents; Atracurium; Cardi

1998
Propofol containing sulfite-potential for injury.
    Chest, 1999, Volume: 116, Issue:4

    Topics: Drug Approval; Drug Hypersensitivity; Drugs, Generic; Humans; Pharmaceutic Aids; Propofol; Risk Fact

1999
Safe induction with propofol following thiopentone anaphylaxis.
    Anaesthesia and intensive care, 1990, Volume: 18, Issue:2

    Topics: Adult; Anaphylaxis; Anesthesia, Intravenous; Arthroscopy; Drug Hypersensitivity; Female; Humans; Pro

1990
[Non-specific histamine liberation and propofol].
    Annales francaises d'anesthesie et de reanimation, 1987, Volume: 6, Issue:4

    Topics: Adult; Anesthetics; Blood Pressure; Drug Hypersensitivity; Female; Heart Rate; Histamine; Histamine

1987
[The amount of histamine released in vivo by hypnotics (thiopental, methohexital, propofol) studied by assays of plasma histamine].
    Allergie et immunologie, 1988, Volume: 20, Issue:9

    Topics: Drug Hypersensitivity; Histamine; Histamine Release; Humans; Methohexital; Phenols; Propofol; Thiope

1988
Ocular manifestation of propofol allergy.
    Anaesthesia, 1989, Volume: 44, Issue:3

    Topics: Adult; Anesthetics; Drug Eruptions; Drug Hypersensitivity; Eye Diseases; Female; Humans; Phenols; Pr

1989
Anaphylactoid reactions following propofol-atracurium sequence.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1989, Volume: 36, Issue:3 Pt 1

    Topics: Adolescent; Adult; Anaphylaxis; Anesthetics; Atracurium; Bronchial Spasm; Drug Eruptions; Drug Hyper

1989
Delayed allergic response to propofol.
    Anaesthesia, 1989, Volume: 44, Issue:6

    Topics: Adult; Anesthetics; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Male; Phenols; Propofo

1989