propofol has been researched along with Drug Abuse, Intravenous in 15 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The propofol information was collected by routine epidemic surveillance and interviews." | 2.90 | An outbreak of HIV infection among people who inject drugs linked to injection of propofol in Taiwan. ( Huang, YC; Huang, YF; Latkin, C; Liao, YH; Lin, MH; Lo, HY; Nelson, KE; Yang, JY, 2019) |
| "Propofol is a recently introduced intravenous anesthetic agent, commonly administered to surgical patients because it induces anesthesia smoothly (i." | 2.67 | Assessing the behavioral effects and abuse potential of propofol bolus injections in healthy volunteers. ( Apfelbaum, JL; Binstock, WB; Coalson, DW; Cutter, T; Flemming, DC; Lichtor, JL; Uitvlugt, AM; Zacny, JP; Zaragoza, JG, 1993) |
| "Propofol is a sedative-hypnotic prescription medication that is widely used in anesthesia, long-term sedation, and conscious sedation." | 2.46 | The abuse potential of propofol. ( Canning, P; Caravati, EM; Wilson, C, 2010) |
| "Propofol is a widely used general anaesthetic with multisite mechanisms and especially ultrashort activation of certain central GABA-A receptors." | 1.35 | A case report of propofol dependence in a physician. ( Bonnet, U; Harkener, J; Scherbaum, N, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 8 (53.33) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, YC | 1 |
| Huang, YF | 1 |
| Lin, MH | 1 |
| Yang, JY | 1 |
| Liao, YH | 1 |
| Lo, HY | 1 |
| Latkin, C | 1 |
| Nelson, KE | 1 |
| Bonnet, U | 1 |
| Harkener, J | 1 |
| Scherbaum, N | 1 |
| Kirby, RR | 1 |
| Colaw, JM | 1 |
| Douglas, MM | 1 |
| Riezzo, I | 1 |
| Centini, F | 1 |
| Neri, M | 1 |
| Rossi, G | 1 |
| Spanoudaki, E | 1 |
| Turillazzi, E | 1 |
| Fineschi, V | 1 |
| Wilson, C | 1 |
| Canning, P | 1 |
| Caravati, EM | 1 |
| Koopmann, A | 1 |
| von der Goltz, C | 1 |
| Hermann, D | 1 |
| Kiefer, F | 1 |
| Maier, C | 1 |
| Leclerc-Springer, J | 1 |
| Lee, J | 1 |
| Kranioti, EF | 1 |
| Mavroforou, A | 1 |
| Mylonakis, P | 1 |
| Michalodimitrakis, M | 1 |
| Roussin, A | 1 |
| Montastruc, JL | 1 |
| Lapeyre-Mestre, M | 1 |
| Zacny, JP | 1 |
| Lichtor, JL | 1 |
| Zaragoza, JG | 1 |
| Coalson, DW | 1 |
| Uitvlugt, AM | 1 |
| Flemming, DC | 1 |
| Binstock, WB | 1 |
| Cutter, T | 1 |
| Apfelbaum, JL | 1 |
| Soyka, M | 1 |
| Sch utz, CG | 1 |
| Iwersen-Bergmann, S | 1 |
| Rösner, P | 1 |
| Kühnau, HC | 1 |
| Junge, M | 1 |
| Schmoldt, A | 1 |
| Fritz, GA | 1 |
| Niemczyk, WE | 1 |
| Cirimele, V | 1 |
| Kintz, P | 1 |
| Doray, S | 1 |
| Ludes, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Observer Rating Scale of Facial Expression Can Predict Dreaming in Propofol Anesthesia[NCT04235894] | 124 participants (Actual) | Observational | 2016-09-07 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for propofol and Drug Abuse, Intravenous
| Article | Year |
|---|---|
The abuse potential of propofol.
Topics: Anesthetics, Intravenous; Animals; Drug and Narcotic Control; Drug Tolerance; Humans; Propofol; Subs | 2010 |
Lethal self administration of propofol (Diprivan). A case report and review of the literature.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Drug Overdose; Female; Humans; Lidocaine; Liver | 2007 |
Pharmacological and clinical evidences on the potential for abuse and dependence of propofol: a review of the literature.
Topics: Anesthetics, Intravenous; Animals; Clinical Trials as Topic; Dopamine; Humans; Models, Animal; Nucle | 2007 |
2 trials available for propofol and Drug Abuse, Intravenous
| Article | Year |
|---|---|
An outbreak of HIV infection among people who inject drugs linked to injection of propofol in Taiwan.
Topics: Adult; Aged; Epidemics; Female; HIV Infections; Humans; Male; Middle Aged; Propofol; Substance Abuse | 2019 |
Assessing the behavioral effects and abuse potential of propofol bolus injections in healthy volunteers.
Topics: Adult; Affect; Arousal; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; | 1993 |
10 other studies available for propofol and Drug Abuse, Intravenous
| Article | Year |
|---|---|
A case report of propofol dependence in a physician.
Topics: Adult; Anesthetics, Intravenous; Diagnosis, Differential; Dose-Response Relationship, Drug; Humans; | 2008 |
Death from propofol: accident, suicide, or murder?
Topics: Anesthetics, Intravenous; Drug Labeling; Drug Overdose; Fatal Outcome; Female; Homicide; Humans; Inj | 2009 |
Brugada-like EKG pattern and myocardial effects in a chronic propofol abuser.
Topics: Adult; Anesthetics, Intravenous; Brugada Syndrome; Death, Sudden, Cardiac; Electrocardiography; Fata | 2009 |
Propofol addiction initiated by anesthetic use.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Colonoscopy; Crohn Disease; Euphoria; Fema | 2011 |
[Life-threatening fentanyl and propofol addiction: interview with a survivor].
Topics: Adult; Analgesics, Opioid; Anesthesiology; Anesthetics, Intravenous; Female; Fentanyl; Humans; Nalox | 2012 |
Propofol abuse in professionals.
Topics: Health Personnel; Humans; Hypnotics and Sedatives; Propofol; Substance Abuse, Intravenous | 2012 |
Propofol dependency.
Topics: Adult; Humans; Hypnotics and Sedatives; Male; Physician Impairment; Propofol; Substance Abuse, Intra | 1997 |
Death after excessive propofol abuse.
Topics: Adult; Anesthetics, Intravenous; Autopsy; Drug Overdose; Humans; Male; Propofol; Reference Standards | 2001 |
Propofol dependency in a lay person.
Topics: Adult; Anesthetics, Intravenous; Attention Deficit Disorder with Hyperactivity; Humans; Male; Propof | 2002 |
Determination of chronic abuse of the anaesthetic agents midazolam and propofol as demonstrated by hair analysis.
Topics: Adult; Anesthetics, Intravenous; Autopsy; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans | 2002 |