propofol has been researched along with Dizzyness in 13 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " With the increasing dose of alfentanil, the morbidity of hypotension and bradycardia increased significantly (P = 0." | 5.69 | A comparative study on the efficacy and safety of propofol combined with different doses of alfentanil in gastroscopy: a randomized controlled trial. ( Guan, ZY; Wang, CM; Wang, LL; Zhang, J; Zhang, YW; Zhao, P, 2023) |
| " Current clinical studies have focused on the use of remimazolam and propofol for general anesthesia (GA) as indicators of safety outcomes in surgical patients, but different studies have reached different conclusions." | 5.41 | Comparison of remimazolam and propofol about safety outcome indicators during general anesthesia in surgical patients: a systematic review and meta-analysis. ( An, L; Bai, X; Chen, R; Gao, H; Huang, X; Tong, R; Wang, C; Wu, X; Yi, J; Zhang, Z, 2023) |
| " Propofol is the most widely used agent for induction of anesthesia and sedation by anesthesiologists." | 5.41 | Remimazolam ( Chang, Y; Chi, KY; Huang, YT, 2023) |
| "This study aims to observe the safety and effectiveness of remimazolam benzenesulfonate combined with alfentanil for painless and comfort anesthesia in plastic surgery." | 3.30 | Use of Remimazolam Combined With Alfentanil for Plastic Surgery Anesthesia Cases: A Clinical Trial. ( Huang, Y; Sun, H; Tan, X; Xu, K, 2023) |
| "The rates of respiratory depression (1." | 3.11 | Effect of additional equipotent fentanyl or sufentanil administration on recovery profiles during propofol-remifentanil-based anaesthesia in patients undergoing gynaecologic laparoscopic surgery: a randomized clinical trial. ( Huang, D; Huang, J; Jian, Q; Li, P; Ma, J; Xie, H; Zeng, W; Zhang, C, 2022) |
| "Propofol combined with opioids can reduce the dosage of propofol and improve the safety of endoscopy." | 3.11 | Sedative effect and safety of different doses of S-ketamine in combination with propofol during gastro-duodenoscopy in school-aged children: a prospective, randomized study. ( Hu, W; Huang, X; Ren, W; Wang, J; Zhang, B; Zhao, X, 2022) |
| "Remimazolam is a novel ultra-short-acting benzodiazepine." | 3.11 | Remimazolam Tosylate Combined with Low-Dose Propofol Improves Sedation and Safety in Hysteroscopy. ( Chang, H; Liao, Q; Qing, W; Tong, J; Yu, R; Zhang, F, 2022) |
| "This study attempted to investigate the effect of intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides on painless induced abortion." | 3.01 | Analysis on the effect of intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides on hemodynamics and analgesia in pregnant females undergoing painless induced abortion. ( Han, Y; Liu, Z; Wu, J; Yang, L, 2021) |
| "Modafinil 200 mg was administered to the treatment group patients 1 h before sedation/analgesia." | 2.75 | Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills. ( Boesjes, H; Galvin, E; Hol, J; Klein, J; Ubben, JF; Verbrugge, SJ, 2010) |
| "Gabapentin is an anticonvulsant drug that has analgesic properties for acute postoperative pain." | 2.74 | The analgesic effect of gabapentin as a prophylactic anticonvulsant drug on postcraniotomy pain: a prospective randomized study. ( Aykac, B; Bingol, CA; Karlikaya, G; Sayin, M; Türe, H; Türe, U, 2009) |
| " We recorded adverse events during the endoscopic procedure and additionally retrieved questionnaires investigating subjective parameters 24 h after the endoscopic procedure." | 1.40 | Safety analysis of endoscopist-directed propofol sedation: a prospective, national multicenter study of 24 441 patients in German outpatient practices. ( Beck, S; Friedrich, K; Gotthardt, DN; Heil, FJ; Rex, DK; Scholl, SG; Sieg, A; Stremmel, W, 2014) |
| " The aim of this prospective observational audit was to evaluate our practice and report the occurrence of adverse events and behavioral reactions related to the use of ketamine, propofol, and midazolam combinations." | 1.35 | Adverse events and behavioral reactions related to ketamine based anesthesia for anorectal manometry in children. ( Dalal, PG; Seth, N; Somerville, N; Taylor, D, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 8 (61.54) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, J | 1 |
| Han, Y | 1 |
| Yang, L | 1 |
| Liu, Z | 1 |
| Zhang, C | 1 |
| Huang, D | 1 |
| Zeng, W | 1 |
| Ma, J | 1 |
| Li, P | 1 |
| Jian, Q | 1 |
| Huang, J | 1 |
| Xie, H | 1 |
| Wang, J | 1 |
| Hu, W | 1 |
| Zhao, X | 1 |
| Ren, W | 1 |
| Huang, X | 2 |
| Zhang, B | 1 |
| Zhang, F | 2 |
| Chang, H | 2 |
| Qing, W | 2 |
| Yu, R | 2 |
| Liao, Q | 2 |
| Tong, J | 2 |
| Wang, LL | 2 |
| Guan, ZY | 2 |
| Wang, CM | 2 |
| Zhang, YW | 2 |
| Zhang, J | 2 |
| Zhao, P | 2 |
| Xu, K | 1 |
| Huang, Y | 1 |
| Tan, X | 1 |
| Sun, H | 1 |
| Wu, X | 1 |
| Wang, C | 1 |
| Gao, H | 1 |
| Bai, X | 1 |
| Zhang, Z | 1 |
| Chen, R | 1 |
| An, L | 1 |
| Yi, J | 1 |
| Tong, R | 1 |
| Chang, Y | 1 |
| Huang, YT | 2 |
| Chi, KY | 1 |
| Sieg, A | 1 |
| Beck, S | 1 |
| Scholl, SG | 1 |
| Heil, FJ | 1 |
| Gotthardt, DN | 1 |
| Stremmel, W | 1 |
| Rex, DK | 1 |
| Friedrich, K | 1 |
| Türe, H | 1 |
| Sayin, M | 1 |
| Karlikaya, G | 1 |
| Bingol, CA | 1 |
| Aykac, B | 1 |
| Türe, U | 1 |
| Galvin, E | 1 |
| Boesjes, H | 1 |
| Hol, J | 1 |
| Ubben, JF | 1 |
| Klein, J | 1 |
| Verbrugge, SJ | 1 |
| Dalal, PG | 1 |
| Taylor, D | 1 |
| Somerville, N | 1 |
| Seth, N | 1 |
| Chittleborough, MC | 1 |
| Osborne, GA | 1 |
| Rudkin, GE | 1 |
| Vickers, D | 1 |
| Leppard, PI | 1 |
| Barlow, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Gabapentin Regimens and Their Effects on Opioid Consumption[NCT03334903] | Phase 4 | 77 participants (Actual) | Interventional | 2018-05-15 | Completed | ||
| A Randomized, Double Blind, Placebo Controlled Evaluation of Modafinil vs Placebo for the Treatment of General Anesthesia Related Delayed Emergence in Patients With the Diagnosis of Obstructive Sleep Apnea[NCT02494102] | Phase 4 | 105 participants (Actual) | Interventional | 2016-02-29 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Surgical site pain. Scale 0-10, with 0 best and 10 worst (NCT03334903)
Timeframe: 2-3 months after surgery (at 2nd postoperative appointment)
| Intervention | score on 10-point scale (Mean) |
|---|---|
| Standard of Care | 2.26 |
| Postoperative Gabapentin Regimen | 2.46 |
Surgical site pain. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | score on a 10-point scale (Mean) |
|---|---|
| Standard of Care | 3.84 |
| Postoperative Gabapentin Regimen | 3.54 |
Sleep quality. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | score on a 10-point scale (Mean) |
|---|---|
| Standard of Care | 5.73 |
| Postoperative Gabapentin Regimen | 6.38 |
Nausea. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | score on a 10-point scale (Mean) |
|---|---|
| Standard of Care | 0.36 |
| Postoperative Gabapentin Regimen | 0.17 |
Satisfaction. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | score on a 10-point scale (Mean) |
|---|---|
| Standard of Care | 7.83 |
| Postoperative Gabapentin Regimen | 8.48 |
Number of days until patients are finished consuming opioid medications after discharge. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | days (Mean) |
|---|---|
| Standard of Care | 14.8 |
| Postoperative Gabapentin Regimen | 18.7 |
Mean opioid consumption, measured in mg of morphine equivalents. (NCT03334903)
Timeframe: 2-3 months following surgery (total amount measured at second postoperative appointment; means assessed afterwards).
| Intervention | morphine equivalents (Mean) |
|---|---|
| Standard of Care | 287.0 |
| Postoperative Gabapentin Regimen | 281.1 |
Length of time of above compared between groups (NCT02494102)
Timeframe: 24 hours
| Intervention | minutes (Mean) |
|---|---|
| Placebo | 53.5 |
| Modafinil | 61.0 |
Postanesthesia quality recovery scale (PQRS). Component and aggregate scoring on the scale. Measures physiology, nociceptive, emotional activities of daily living cognitive and overall patient perspective. The scale is dimensionless and the aggregate of all individually tested dimensions is scaled from 17-65. A higher value implies improved postanesthesia recovery. Mean difference was assessed in each patient and aggregated thus patients with no difference between pre- and post-operative scores were zeroed (received a zero score if the difference was zero). A negative value was associated with worse outcome. (NCT02494102)
Timeframe: baseline and 6 hours after surgery
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | -5.67 |
| Modafinil | -8.91 |
2 reviews available for propofol and Dizzyness
| Article | Year |
|---|---|
Comparison of remimazolam and propofol about safety outcome indicators during general anesthesia in surgical patients: a systematic review and meta-analysis.
Topics: Anesthesia, General; Benzodiazepines; Dizziness; Humans; Hypnotics and Sedatives; Hypotension; Hypox | 2023 |
Remimazolam
Topics: Anesthesia; Benzodiazepines; Bradycardia; Conscious Sedation; Dizziness; Humans; Hypotension; Pain; | 2023 |
9 trials available for propofol and Dizzyness
| Article | Year |
|---|---|
Analysis on the effect of intravenous anesthesia with dexmedetomidine and propofol combined with seaweed polysaccharides on hemodynamics and analgesia in pregnant females undergoing painless induced abortion.
Topics: Abortion, Induced; Adult; Anesthetics, Intravenous; Arterial Pressure; Carrageenan; Deep Sedation; D | 2021 |
Effect of additional equipotent fentanyl or sufentanil administration on recovery profiles during propofol-remifentanil-based anaesthesia in patients undergoing gynaecologic laparoscopic surgery: a randomized clinical trial.
Topics: Anesthesia; Delirium; Dizziness; Female; Fentanyl; Humans; Laparoscopy; Nausea; Propofol; Remifentan | 2022 |
Sedative effect and safety of different doses of S-ketamine in combination with propofol during gastro-duodenoscopy in school-aged children: a prospective, randomized study.
Topics: Anesthesia Recovery Period; Anesthetics, Intravenous; Child; Dizziness; Duodenoscopy; Humans; Hypnot | 2022 |
Remimazolam Tosylate Combined with Low-Dose Propofol Improves Sedation and Safety in Hysteroscopy.
Topics: Benzodiazepines; Dizziness; Female; Humans; Hypnotics and Sedatives; Hypotension; Hysteroscopy; Naus | 2022 |
Remimazolam Tosylate Combined with Low-Dose Propofol Improves Sedation and Safety in Hysteroscopy.
Topics: Benzodiazepines; Dizziness; Female; Humans; Hypnotics and Sedatives; Hypotension; Hysteroscopy; Naus | 2022 |
Remimazolam Tosylate Combined with Low-Dose Propofol Improves Sedation and Safety in Hysteroscopy.
Topics: Benzodiazepines; Dizziness; Female; Humans; Hypnotics and Sedatives; Hypotension; Hysteroscopy; Naus | 2022 |
Remimazolam Tosylate Combined with Low-Dose Propofol Improves Sedation and Safety in Hysteroscopy.
Topics: Benzodiazepines; Dizziness; Female; Humans; Hypnotics and Sedatives; Hypotension; Hysteroscopy; Naus | 2022 |
A comparative study on the efficacy and safety of propofol combined with different doses of alfentanil in gastroscopy: a randomized controlled trial.
Topics: Alfentanil; Anesthetics, Intravenous; Bradycardia; Dizziness; Gastroscopy; Humans; Hypotension; Hypo | 2023 |
A comparative study on the efficacy and safety of propofol combined with different doses of alfentanil in gastroscopy: a randomized controlled trial.
Topics: Alfentanil; Anesthetics, Intravenous; Bradycardia; Dizziness; Gastroscopy; Humans; Hypotension; Hypo | 2023 |
A comparative study on the efficacy and safety of propofol combined with different doses of alfentanil in gastroscopy: a randomized controlled trial.
Topics: Alfentanil; Anesthetics, Intravenous; Bradycardia; Dizziness; Gastroscopy; Humans; Hypotension; Hypo | 2023 |
A comparative study on the efficacy and safety of propofol combined with different doses of alfentanil in gastroscopy: a randomized controlled trial.
Topics: Alfentanil; Anesthetics, Intravenous; Bradycardia; Dizziness; Gastroscopy; Humans; Hypotension; Hypo | 2023 |
Use of Remimazolam Combined With Alfentanil for Plastic Surgery Anesthesia Cases: A Clinical Trial.
Topics: Alfentanil; Anesthesia, Local; Benzenesulfonates; Dizziness; Glossoptosis; Humans; Nausea; Propofol; | 2023 |
The analgesic effect of gabapentin as a prophylactic anticonvulsant drug on postcraniotomy pain: a prospective randomized study.
Topics: Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; | 2009 |
Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia Recovery Period; Anesthetics, Inha | 2010 |
Double-blind comparison of patient recovery after induction with propofol or thiopentone for day-case relaxant general anaesthesia.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Intravenous; Dizzines | 1992 |
2 other studies available for propofol and Dizzyness
| Article | Year |
|---|---|
Safety analysis of endoscopist-directed propofol sedation: a prospective, national multicenter study of 24 441 patients in German outpatient practices.
Topics: Colonoscopy; Conscious Sedation; Dizziness; Dose-Response Relationship, Drug; Drug Therapy, Combinat | 2014 |
Adverse events and behavioral reactions related to ketamine based anesthesia for anorectal manometry in children.
Topics: Anal Canal; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, | 2008 |