propofol has been researched along with Disease Exacerbation in 11 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In total, our results proved that targeting miR340/CDK2 axis was novel to enhance the anti-tumor effects of propofol in bladder cancer in vitro, and our study provided alternative therapeutic strategies for clinical treatment of bladder cancer." | 8.02 | Propofol suppressed cell proliferation and enhanced apoptosis of bladder cancer cells by regulating the miR-340/CDK2 signal axis. ( Ding, HJ; Li, Y; Liu, JT; Mei, XP; Tan, SH; Tang, YX, 2021) |
| "Propofol is a commonly used drug for the induction and maintenance of anesthesia." | 5.56 | Propofol‑induced HOXA11‑AS promotes proliferation, migration and invasion, but inhibits apoptosis in hepatocellular carcinoma cells by targeting miR‑4458. ( Feng, Y; Jin, Y; Liu, J; Song, F, 2020) |
| "In case 1, a 19-year-old, 59-kg man with Becker muscular dystrophy and mental retardation was scheduled for dental treatment under general anesthesia." | 5.33 | Continuous infusion propofol general anesthesia for dental treatment in patients with progressive muscular dystrophy. ( Kawaai, H; Tanaka, K; Yamazaki, S, 2005) |
| "In total, our results proved that targeting miR340/CDK2 axis was novel to enhance the anti-tumor effects of propofol in bladder cancer in vitro, and our study provided alternative therapeutic strategies for clinical treatment of bladder cancer." | 4.02 | Propofol suppressed cell proliferation and enhanced apoptosis of bladder cancer cells by regulating the miR-340/CDK2 signal axis. ( Ding, HJ; Li, Y; Liu, JT; Mei, XP; Tan, SH; Tang, YX, 2021) |
| "Propofol is a commonly used drug for the induction and maintenance of anesthesia." | 1.56 | Propofol‑induced HOXA11‑AS promotes proliferation, migration and invasion, but inhibits apoptosis in hepatocellular carcinoma cells by targeting miR‑4458. ( Feng, Y; Jin, Y; Liu, J; Song, F, 2020) |
| "The apoptosis and metastasis were measured by flow cytometry and transwell assays." | 1.56 | Exosomal lncRNA H19 promotes the progression of hepatocellular carcinoma treated with Propofol via miR-520a-3p/LIMK1 axis. ( Ai, Y; He, J; Liu, J; Wang, D; Xing, N; Yang, J; Yang, T; Zhao, H, 2020) |
| "Anesthetics are unavoidable to colorectal cancer (CRC) patients who underwent surgical treatment." | 1.43 | Differential role of intravenous anesthetics in colorectal cancer progression: implications for clinical application. ( Chen, Y; Deng, F; Ouyang, M; Sun, X; Tang, J; Tao, T; Wang, X; Xu, L; Yao, X; Zhao, L, 2016) |
| "In case 1, a 19-year-old, 59-kg man with Becker muscular dystrophy and mental retardation was scheduled for dental treatment under general anesthesia." | 1.33 | Continuous infusion propofol general anesthesia for dental treatment in patients with progressive muscular dystrophy. ( Kawaai, H; Tanaka, K; Yamazaki, S, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 4 (36.36) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, Y | 1 |
| Lu, H | 1 |
| Ren, X | 1 |
| Li, F | 1 |
| Bu, W | 1 |
| Liu, W | 1 |
| Dailey, WP | 1 |
| Saeki, H | 1 |
| Gabrielson, K | 1 |
| Abraham, R | 1 |
| Eckenhoff, R | 1 |
| Gao, WD | 1 |
| Song, F | 1 |
| Liu, J | 2 |
| Feng, Y | 1 |
| Jin, Y | 1 |
| Wang, D | 1 |
| Xing, N | 1 |
| Yang, T | 1 |
| Zhao, H | 1 |
| He, J | 1 |
| Ai, Y | 1 |
| Yang, J | 1 |
| Tan, SH | 1 |
| Ding, HJ | 1 |
| Mei, XP | 1 |
| Liu, JT | 1 |
| Tang, YX | 1 |
| Li, Y | 1 |
| Takeyama, K | 1 |
| Sakamoto, R | 1 |
| Yoshikawa, M | 1 |
| Suzuki, T | 1 |
| Deng, F | 1 |
| Ouyang, M | 1 |
| Wang, X | 1 |
| Yao, X | 1 |
| Chen, Y | 1 |
| Tao, T | 1 |
| Sun, X | 1 |
| Xu, L | 1 |
| Tang, J | 1 |
| Zhao, L | 1 |
| Morozowich, ST | 1 |
| Saslow, SB | 1 |
| Li, Z | 1 |
| Chen, X | 1 |
| Meng, J | 1 |
| Deng, L | 1 |
| Ma, H | 1 |
| Csete, M | 1 |
| Xiong, L | 1 |
| Kawaai, H | 1 |
| Tanaka, K | 1 |
| Yamazaki, S | 1 |
| Rosen, DJ | 1 |
| Nicoara, A | 1 |
| Koshy, N | 1 |
| Wedderburn, RV | 1 |
| Hamaguchi, S | 1 |
| Kitajima, T | 1 |
| Yasuda, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of The Effects Of General Anesthesia and PECS Block Methods on Blood Leukocyte, Neutrophil, Lymphocyte, and Platelet Counts in Patients With Breast Cancer[NCT06151639] | 26 participants (Actual) | Observational | 2022-08-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for propofol and Disease Exacerbation
| Article | Year |
|---|---|
Too much of a good thing? Tracing the history of the propofol infusion syndrome.
Topics: Accidents, Traffic; Acute Kidney Injury; Adolescent; Adult; Anuria; Brain Injuries; Critical Care; D | 2007 |
10 other studies available for propofol and Disease Exacerbation
| Article | Year |
|---|---|
Fropofol prevents disease progression in mice with hypertrophic cardiomyopathy.
Topics: Animals; Calcium Signaling; Cardiac Myosins; Cardiomyopathy, Hypertrophic; Disease Models, Animal; D | 2020 |
Propofol‑induced HOXA11‑AS promotes proliferation, migration and invasion, but inhibits apoptosis in hepatocellular carcinoma cells by targeting miR‑4458.
Topics: Anesthetics, Intravenous; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Prol | 2020 |
Exosomal lncRNA H19 promotes the progression of hepatocellular carcinoma treated with Propofol via miR-520a-3p/LIMK1 axis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cocu | 2020 |
Propofol suppressed cell proliferation and enhanced apoptosis of bladder cancer cells by regulating the miR-340/CDK2 signal axis.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclin-De | 2021 |
Case of Wenckebach-type atrioventricular block caused by administration of indigo carmine.
Topics: Adult; Anesthesia, General; Atrioventricular Block; Coloring Agents; Disease Progression; Electrocar | 2014 |
Differential role of intravenous anesthetics in colorectal cancer progression: implications for clinical application.
Topics: Anesthetics, Intravenous; Animals; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Dexmedetom | 2016 |
Progression of asymptomatic bifascicular block to complete heart block during upper gastrointestinal endoscopy with propofol sedation.
Topics: Aged, 80 and over; Conscious Sedation; Disease Progression; Endoscopy, Gastrointestinal; Female; Hea | 2009 |
ED50 and recovery times after propofol in rats with graded cirrhosis.
Topics: Alanine Transaminase; Anesthetics, Intravenous; Animals; Aspartate Aminotransferases; Biomarkers; Ca | 2012 |
Continuous infusion propofol general anesthesia for dental treatment in patients with progressive muscular dystrophy.
Topics: Adult; Anesthesia, Dental; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenou | 2005 |
[Anesthetic management of a patient with postthymectomy myasthenia gravis].
Topics: Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenous; Disease Progression; Fentanyl; | 1999 |