Page last updated: 2024-11-03

propofol and Diathesis

propofol has been researched along with Diathesis in 18 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"Propofol infusion syndrome is a rare condition that mainly affects critically ill patients who receive high doses of this hypnotic for a long time."7.96Propofol infusion syndrome; are high doses always required? ( Boliart de San Félix, Y; Fernández Morales, M; Sánchez Royo, E; Subirà González, A; Vila Lolo, C, 2020)
"Propofol infusion syndrome is a rare condition that mainly affects critically ill patients who receive high doses of this hypnotic for a long time."3.96Propofol infusion syndrome; are high doses always required? ( Boliart de San Félix, Y; Fernández Morales, M; Sánchez Royo, E; Subirà González, A; Vila Lolo, C, 2020)
" The appearance of muscle spasms as a result of the use of propofol, forced us into a second anaesthesia to perform total intravenous anaesthesia with Midazolam."3.85General anesthesia in patients with syndrome of Poland. ( Díaz-Crespo, J; García-Herrera, F; Vázquez-Mambrilla, Y, 2017)
" In vitro, human MHS muscle samples were exposed to propofol and changes in (a) baseline tension and (b) contracture tension on exposure to halothane and caffeine were measured."3.68Propofol is a 'safe' anaesthetic agent in malignant hyperthermia susceptible patients. ( Couchman, KG; McKenzie, AJ; Pollock, N, 1992)
"Propofol in KH was perfused at 12 microg/ml for the first 15 min of reperfusion and subsequently reduced to 5 microg/ml in propofol treatment groups."1.32Propofol enhances ischemic tolerance of middle-aged rat hearts: effects on 15-F(2t)-isoprostane formation and tissue antioxidant capacity. ( Ansley, DM; Godin, DV; Xia, Z, 2003)
"Anaesthetic techniques for malignant hyperthermia susceptible (MHS) patients should include drugs which do not trigger MH and provide stress free conditions."1.28Effect of propofol on the malignant hyperthermia susceptible pig model. ( Adnet, P; Becq, MC; Krivosic-Horber, R; Reyfort, H, 1989)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's6 (33.33)18.2507
2000's5 (27.78)29.6817
2010's3 (16.67)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Subirà González, A1
Fernández Morales, M1
Sánchez Royo, E1
Boliart de San Félix, Y1
Vila Lolo, C1
Zhang, JP1
Zhang, WJ1
Yang, M1
Fang, H1
Visvabharathy, L2
Freitag, NE2
Xayarath, B1
Weinberg, G1
Shilling, RA1
Díaz-Crespo, J1
Vázquez-Mambrilla, Y1
García-Herrera, F1
Kumar, N1
Hu, WT1
Dueñas, N1
Zaballos, M1
Xia, Z1
Godin, DV1
Ansley, DM1
Sarti, A1
Busoni, P1
Dell'Oste, C1
Bussolin, L1
Hudcova, J1
Schumann, R1
Pollock, AN1
McKenzie, AJ2
Hodges, M1
Snoeck, MM1
Plötz, FB1
Waalkens, HJ1
Verkade, HJ1
Hawkes, CA1
Couchman, KG1
Pollock, N1
Crosby, E1
Harrison, GG1
Cartwright, DP1
Krivosic-Horber, R1
Reyfort, H1
Becq, MC1
Adnet, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Changes of Hemodynamics and Vital Organ Function in Intracerebral Hemorrhage During Different General Anesthesia[NCT03129009]90 participants (Anticipated)Interventional2017-04-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for propofol and Diathesis

ArticleYear
Incidence of vomiting in susceptible children under regional analgesia with two different anaesthetic techniques.
    Paediatric anaesthesia, 2004, Volume: 14, Issue:3

    Topics: Anesthesia, Conduction; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous

2004

Other Studies

17 other studies available for propofol and Diathesis

ArticleYear
Propofol infusion syndrome; are high doses always required?
    Revista espanola de anestesiologia y reanimacion, 2020, Volume: 67, Issue:3

    Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Chemical

2020
Propofol attenuates lung ischemia/reperfusion injury though the involvement of the MALAT1/microRNA-144/GSK3β axis.
    Molecular medicine (Cambridge, Mass.), 2021, 07-15, Volume: 27, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Autophagy; Biomarkers; Cytokines; Disease Models, Animal; Disease

2021
Propofol Sedation Exacerbates Kidney Pathology and Dissemination of Bacteria during Staphylococcus aureus Bloodstream Infections.
    Infection and immunity, 2017, Volume: 85, Issue:7

    Topics: Animals; Bacteremia; Bacterial Load; Dendritic Cells; Disease Models, Animal; Disease Susceptibility

2017
Propofol Increases Host Susceptibility to Microbial Infection by Reducing Subpopulations of Mature Immune Effector Cells at Sites of Infection.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Animals; Animals, Outbred Strains; Bacterial Infections; Cell Count; Cells, Cultured; Cross Infectio

2015
General anesthesia in patients with syndrome of Poland.
    Revista espanola de anestesiologia y reanimacion, 2017, Volume: 64, Issue:2

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Breast; Breast Im

2017
Extrapyramidal reaction to ondansetron and propofol.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Jan-30, Volume: 24, Issue:2

    Topics: Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Antiemetics; Basal Ganglia Diseases; Di

2009
[Anesthesia for parathyroidectomy in an elderly patient with dermatomyositis and high risk of bronchial aspiration].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:5

    Topics: Aged, 80 and over; Androstanols; Anesthesia, Intravenous; Anesthetics, Intravenous; Carcinoma, Squam

2009
Propofol enhances ischemic tolerance of middle-aged rat hearts: effects on 15-F(2t)-isoprostane formation and tissue antioxidant capacity.
    Cardiovascular research, 2003, Jul-01, Volume: 59, Issue:1

    Topics: Aging; Animals; Antioxidants; Disease Susceptibility; Male; Myocardial Ischemia; Myocardial Reperfus

2003
Undiagnosed catecholamine-secreting paraganglioma and coexisting carcinoid in a patient with MH susceptibility: an unusual anesthetic challenge.
    Journal of anesthesia, 2007, Volume: 21, Issue:1

    Topics: Adrenergic alpha-Agonists; Adult; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenou

2007
Propofol and malignant hyperthermia susceptibility.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:5

    Topics: Acidosis; Adolescent; Adult; Aged; Anesthetics, Intravenous; Arrhythmias, Cardiac; Cause of Death; C

1997
Fatal outcome after propofol sedation in children.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:5

    Topics: Anesthetics, Intravenous; Cause of Death; Child; Dantrolene; Disease Susceptibility; Humans; Hypnoti

1997
Factitious halothane detection during trigger-free anesthesia in a malignant hyperthermia susceptible patient.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:6

    Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Arthrodesis; Arthroscopy; Disease Susceptibilit

1999
Propofol is a 'safe' anaesthetic agent in malignant hyperthermia susceptible patients.
    Anaesthesia and intensive care, 1992, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Caffeine; Contracture; Disease Susceptibility; Halothane

1992
Does propofol-nitrous oxide anaesthesia provide autonomic hyperreflexia (AH) prophylaxis in susceptible patients?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:5 Pt 1

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Autonomic Nervous System; Blood Pressure; Di

1992
Propofol in malignant hyperthermia.
    Lancet (London, England), 1991, Feb-23, Volume: 337, Issue:8739

    Topics: Anesthesia; Biopsy; Disease Susceptibility; Humans; In Vitro Techniques; Malignant Hyperthermia; Mus

1991
Propofol in patients susceptible to malignant hyperpyrexia.
    Anaesthesia, 1989, Volume: 44, Issue:2

    Topics: Anesthetics; Disease Susceptibility; Female; Humans; Malignant Hyperthermia; Middle Aged; Phenols; P

1989
Effect of propofol on the malignant hyperthermia susceptible pig model.
    British journal of anaesthesia, 1989, Volume: 62, Issue:6

    Topics: Anesthetics; Animals; Disease Models, Animal; Disease Susceptibility; Malignant Hyperthermia; Phenol

1989