Page last updated: 2024-11-03

propofol and Depression, Involutional

propofol has been researched along with Depression, Involutional in 33 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.

Research Excerpts

ExcerptRelevanceReference
" We tested our hypothesis that ketamine-based anesthesia for ECT results in superior improvement in treatment-resistant MDD outcomes compared with propofol-based anesthesia."9.27Ketamine-based anesthesia improves electroconvulsive therapy outcomes: a randomized-controlled study. ( Balbuena, L; Bi, H; Bowen, R; Gamble, JJ; Prasad, R; Sanjanwala, R; Weisgerber, G, 2018)
" We tested our hypothesis that ketamine-based anesthesia for ECT results in superior improvement in treatment-resistant MDD outcomes compared with propofol-based anesthesia."5.27Ketamine-based anesthesia improves electroconvulsive therapy outcomes: a randomized-controlled study. ( Balbuena, L; Bi, H; Bowen, R; Gamble, JJ; Prasad, R; Sanjanwala, R; Weisgerber, G, 2018)
"3 mg/kg ketamine and then underwent ECT under propofol anesthesia, and a control group, which received isovolumetric placebo (normal saline) and then underwent ECT under propofol anesthesia."5.24Effect of Low Dose of Ketamine on Learning Memory Function in Patients Undergoing Electroconvulsive Therapy-A Randomized, Double-Blind, Controlled Clinical Study. ( Chen, J; Chen, Q; Hao, X; Li, X; Luo, Q; Meng, H; Min, S; Peng, L, 2017)
"Ketamine in electroconvulsive therapy (ECT) anesthesia has been reported to be associated with better seizure quality and longer duration compared with methohexital anesthesia."5.17Effects of S-ketamine as an anesthetic adjuvant to propofol on treatment response to electroconvulsive therapy in treatment-resistant depression: a randomized pilot study. ( Björkqvist, M; Chrapek, W; Häkkinen, H; Järventausta, K; Kampman, O; Leinonen, E; Tuohimaa, K; Yli-Hankala, A, 2013)
" Algorithm-based charge dosing was used."2.78Effect of propofol versus sodium thiopental on electroconvulsive therapy in major depressive disorder: a randomized double-blind controlled clinical trial. ( Balkç, A; Deniz, S; Erdem, M; Özdemir, B; Öznur, T; Purtuloğlu, T; Ünlü, G, 2013)
"Propofol was administered until the patients did not respond to a verbal command."2.74Premedication with dexmedetomidine and midazolam attenuates agitation after electroconvulsive therapy. ( Bulut, M; Ganidagli, S; Koruk, S; Mizrak, A; Oner, U, 2009)
"With methohexital, there was a clear postictal increase of mean blood pressure from 126/78 mm Hg to 161/102 mm Hg, whereas there was no increase with propofol (p = 0."2.69Propofol and methohexital as anesthetic agents for electroconvulsive therapy (ECT): a comparison of seizure-quality measures and vital signs. ( Geretsegger, C; Kartnig, C; Rochowanski, E; Unterrainer, AF, 1998)
"Propofol-treated patients showed a higher mean stimulus charge (etomidate = 227."1.39A retrospective comparison of the effects of propofol and etomidate on stimulus variables and efficacy of electroconvulsive therapy in depressed inpatients. ( Birkenhäger, TK; Graveland, PE; van den Broek, WW; Wierdsma, AI, 2013)
"Propofol was also associated with a significantly higher requirement for bilateral ECT and higher stimulus dosing."1.38A within-subject comparison of propofol and methohexital anesthesia for electroconvulsive therapy. ( Anderson, EL; Bobb, A; Jayaram, G; Pulia, K; Reti, I; Vaidya, PV, 2012)
"Although mean motor seizure durations were significantly longer in groups R1 and R2 than in group P (P < 0."1.37Effect of divided supplementation of remifentanil on seizure duration and hemodynamic responses during electroconvulsive therapy under propofol anesthesia. ( Higuchi, M; Kawagishi, T; Nishikawa, K; Shimodate, Y; Yamakage, M, 2011)
"The induction of a seizure is a core event in successful ECT."1.33Remifentanil supplementation of propofol during electroconvulsive therapy: effect on seizure duration and cardiovascular stability. ( Amiaz, R; Aronov, S; Etchin, A; Grunhaus, L; Vishne, T, 2005)
"Propofol was well tolerated with occasional, transient, and reversible drops in blood the pressure being the only adverse event noted."1.33Propofol for the management of emergence agitation after electroconvulsive therapy: review of a case series. ( Augoustides, JG; Datto, CJ; O'Reardon, JP; Takieddine, N, 2006)
"Propofol was used as an anesthetic."1.31Efficacy and safety of venlafaxine-ECT combination in treatment-resistant depression. ( Elizagarate, E; Gonzalez, N; Gonzalez-Pinto, A; Gutierrez, M; Mico, JA; Perez de Heredia, JL, 2002)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (6.06)18.2507
2000's10 (30.30)29.6817
2010's20 (60.61)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Beilstein, CM1
Meyer, A1
Lehmann, LE1
Wuethrich, PY1
Zhang, M1
Rosenheck, R1
Lin, X1
Li, Q1
Zhou, Y1
Xiao, Y1
Huang, X1
Fan, N1
He, H1
Wojdacz, R1
Święcicki, Ł1
Antosik-Wójcińska, A1
Mechri, A1
Zaafrane, H1
Khalifa, MH1
Toumi, S1
Zaafrane, F1
Gaha, L1
Gamble, JJ1
Bi, H1
Bowen, R1
Weisgerber, G1
Sanjanwala, R1
Prasad, R1
Balbuena, L1
Järventausta, K1
Chrapek, W1
Kampman, O1
Tuohimaa, K1
Björkqvist, M1
Häkkinen, H1
Yli-Hankala, A1
Leinonen, E1
Cohen, MB1
Stewart, JT2
Kellner, CH2
Briggs, MC1
Pasculli, RM1
Bryson, EO2
Wang, X2
Graveland, PE1
Wierdsma, AI1
van den Broek, WW1
Birkenhäger, TK1
Tzabazis, A1
Schmitt, HJ1
Ihmsen, H1
Schmidtlein, M1
Zimmermann, R1
Wielopolski, J1
Münster, T1
Küçük, A1
Karababa, F1
Yüce, HH1
Yalçin, S1
Imashuku, Y1
Kanemoto, K1
Senda, M1
Matsubara, M1
Bruylandt, R1
Van den Abbeele, D1
Jacobs, T1
Wouters, P1
Audenaert, K1
Lemmens, G1
Chen, Q1
Min, S1
Hao, X1
Peng, L1
Meng, H1
Luo, Q1
Chen, J1
Li, X1
Erdil, F1
Demirbilek, S1
Begec, Z1
Ozturk, E1
Ersoy, MO1
Mizrak, A1
Koruk, S1
Ganidagli, S1
Bulut, M1
Oner, U1
Kikuchi, A1
Yasui-Furukori, N1
Fujii, A1
Katagai, H1
Kaneko, S1
Nishikawa, K1
Higuchi, M1
Kawagishi, T1
Shimodate, Y1
Yamakage, M1
Vaidya, PV1
Anderson, EL1
Bobb, A1
Pulia, K1
Jayaram, G1
Reti, I1
Popeo, DM1
Chen, Y1
Zhou, X1
Liu, F1
Zhang, T1
Zhang, C1
Purtuloğlu, T1
Özdemir, B1
Erdem, M1
Deniz, S1
Balkç, A1
Ünlü, G1
Öznur, T1
Caliyurt, O1
Vardar, E1
Tuglu, C1
Abay, E1
Vishne, T1
Aronov, S1
Amiaz, R1
Etchin, A1
Grunhaus, L1
O'Reardon, JP1
Takieddine, N1
Datto, CJ1
Augoustides, JG1
Rosa, MA1
Rosa, MO1
Marcolin, MA1
Fregni, F1
Geretsegger, C2
Nickel, M1
Judendorfer, B1
Rochowanski, E2
Novak, E1
Aichhorn, W1
Eranti, SV1
Mogg, AJ1
Pluck, GC1
Landau, S1
McLoughlin, DM1
Shaw, IH1
McKeith, IG1
Kartnig, C1
Unterrainer, AF1
Gonzalez-Pinto, A1
Gutierrez, M1
Gonzalez, N1
Elizagarate, E1
Perez de Heredia, JL1
Mico, JA1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Randomized Double Blinded Control Trial Using Ketamine or Propofol Anesthesia for Electroconvulsive Therapy: Improving Treatment-Resistant Depression[NCT01935115]Phase 427 participants (Actual)Interventional2013-09-30Completed
Effect of Subanesthetic Dose of Ketamine Combined With Propofol on Cognitive Function in Depressive Patients Undergoing Electroconvulsive Therapy ---a Randomized Control Double-Blind Clinical Trial[NCT02305394]Phase 4132 participants (Anticipated)Interventional2015-01-31Not yet recruiting
Comparison of Propofol Target-Controlled Infusion Anesthesia and Bolus Injection in Electroconvulsive Therapy: A Randomized Controlled Trial[NCT03863925]Phase 440 participants (Actual)Interventional2017-08-15Completed
The Effects of Sevoflurane or Ketamine on QTc Interval During Electroconvulsive Therapy[NCT01870219]Phase 424 participants (Actual)Interventional2012-02-29Completed
Inonu University, Turgut Ozal Medical Center, Department of Anesthesiology and Reanimation Malatya[NCT02271555]Phase 458 participants (Anticipated)Interventional2014-10-31Not yet recruiting
Effects of Low-dose Ketamine as an Adjunct to Propofol-based Anesthesia for Electroconvulsive Therapy[NCT02579642]Phase 448 participants (Actual)Interventional2015-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for propofol and Depression, Involutional

ArticleYear
Comparison of the effect of intravenous anesthetics used for anesthesia during electroconvulsive therapy on the hemodynamic safety and the course of ECT.
    Psychiatria polska, 2017, Dec-30, Volume: 51, Issue:6

    Topics: Anesthetics; Anesthetics, Intravenous; Autonomic Nervous System; Bipolar Disorder; Depressive Disord

2017

Trials

12 trials available for propofol and Depression, Involutional

ArticleYear
A randomized clinical trial of adjunctive ketamine anesthesia in electro-convulsive therapy for depression.
    Journal of affective disorders, 2018, Volume: 227

    Topics: Adult; Anesthetics, Dissociative; Anesthetics, Intravenous; Antidepressive Agents; Bipolar Disorder;

2018
Ketamine-based anesthesia improves electroconvulsive therapy outcomes: a randomized-controlled study.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2018, Volume: 65, Issue:6

    Topics: Adult; Anesthesia; Anesthetics, Dissociative; Anesthetics, Intravenous; Depressive Disorder, Major;

2018
Effects of S-ketamine as an anesthetic adjuvant to propofol on treatment response to electroconvulsive therapy in treatment-resistant depression: a randomized pilot study.
    The journal of ECT, 2013, Volume: 29, Issue:3

    Topics: Adjuvants, Anesthesia; Adult; Aged; Aged, 80 and over; Anesthesia; Anesthesia Recovery Period; Anest

2013
Effect of Low Dose of Ketamine on Learning Memory Function in Patients Undergoing Electroconvulsive Therapy-A Randomized, Double-Blind, Controlled Clinical Study.
    The journal of ECT, 2017, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthesia; Anesthetics, Intravenous; Asian People; Depressive Disorder, Ma

2017
Effects of propofol or etomidate on QT interval during electroconvulsive therapy.
    The journal of ECT, 2009, Volume: 25, Issue:3

    Topics: Adult; Anesthesia; Anesthetics, Intravenous; Blood Pressure; Cross-Over Studies; Depressive Disorder

2009
Premedication with dexmedetomidine and midazolam attenuates agitation after electroconvulsive therapy.
    Journal of anesthesia, 2009, Volume: 23, Issue:1

    Topics: Adult; Anesthesia; Bipolar Disorder; Blood Pressure; Depressive Disorder, Major; Dexmedetomidine; El

2009
Effects of propofol and ketamine as combined anesthesia for electroconvulsive therapy in patients with depressive disorder.
    The journal of ECT, 2012, Volume: 28, Issue:2

    Topics: Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Depressive Disorder, Maj

2012
Effects of propofol and ketamine as combined anesthesia for electroconvulsive therapy in patients with depressive disorder.
    The journal of ECT, 2012, Volume: 28, Issue:2

    Topics: Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Depressive Disorder, Maj

2012
Effects of propofol and ketamine as combined anesthesia for electroconvulsive therapy in patients with depressive disorder.
    The journal of ECT, 2012, Volume: 28, Issue:2

    Topics: Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Depressive Disorder, Maj

2012
Effects of propofol and ketamine as combined anesthesia for electroconvulsive therapy in patients with depressive disorder.
    The journal of ECT, 2012, Volume: 28, Issue:2

    Topics: Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Depressive Disorder, Maj

2012
Effects of propofol and ketamine as combined anesthesia for electroconvulsive therapy in patients with depressive disorder.
    The journal of ECT, 2012, Volume: 28, Issue:2

    Topics: Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Depressive Disorder, Maj

2012
Effects of propofol and ketamine as combined anesthesia for electroconvulsive therapy in patients with depressive disorder.
    The journal of ECT, 2012, Volume: 28, Issue:2

    Topics: Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Depressive Disorder, Maj

2012
Effects of propofol and ketamine as combined anesthesia for electroconvulsive therapy in patients with depressive disorder.
    The journal of ECT, 2012, Volume: 28, Issue:2

    Topics: Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Depressive Disorder, Maj

2012
Effects of propofol and ketamine as combined anesthesia for electroconvulsive therapy in patients with depressive disorder.
    The journal of ECT, 2012, Volume: 28, Issue:2

    Topics: Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Depressive Disorder, Maj

2012
Effects of propofol and ketamine as combined anesthesia for electroconvulsive therapy in patients with depressive disorder.
    The journal of ECT, 2012, Volume: 28, Issue:2

    Topics: Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Depressive Disorder, Maj

2012
Effect of propofol versus sodium thiopental on electroconvulsive therapy in major depressive disorder: a randomized double-blind controlled clinical trial.
    The journal of ECT, 2013, Volume: 29, Issue:1

    Topics: Adult; Age Factors; Algorithms; Body Mass Index; Depressive Disorder, Major; Diagnostic and Statisti

2013
Effects of propofol on electroconvulsive therapy seizure duration.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2004, Volume: 49, Issue:10

    Topics: Adult; Anticonvulsants; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Humans; Male;

2004
Cardiovascular effects of anesthesia in ECT: a randomized, double-blind comparison of etomidate, propofol, and thiopental.
    The journal of ECT, 2007, Volume: 23, Issue:1

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Cardiovascular System; Depressive Disorder

2007
Propofol and methohexital as anesthetic agents for electroconvulsive therapy: a randomized, double-blind comparison of electroconvulsive therapy seizure quality, therapeutic efficacy, and cognitive performance.
    The journal of ECT, 2007, Volume: 23, Issue:4

    Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Bipolar Disorder; Blood Pressure; Chronic Dise

2007
Propofol and methohexital as anesthetic agents for electroconvulsive therapy (ECT): a comparison of seizure-quality measures and vital signs.
    The journal of ECT, 1998, Volume: 14, Issue:1

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Carbon Dioxide; Cross-Over

1998

Other Studies

20 other studies available for propofol and Depression, Involutional

ArticleYear
Comments on "Postanesthesia Recovery Unit Optimization for Patients With Postictal Agitation Secondary to Electroconvulsive Therapy" by Arora et al.
    The journal of ECT, 2023, Dec-01, Volume: 39, Issue:4

    Topics: Depressive Disorder, Major; Electroconvulsive Therapy; Humans; Propofol; Psychomotor Agitation

2023
    The Pan African medical journal, 2018, Volume: 29

    Topics: Adolescent; Adult; Age Factors; Aged; Anesthetics; Depressive Disorder, Major; Electroconvulsive The

2018
Treatment of post-electroconvulsive therapy agitation with dexmedetomidine.
    The journal of ECT, 2013, Volume: 29, Issue:2

    Topics: Aged; Depressive Disorder, Major; Dexmedetomidine; Electroconvulsive Therapy; Humans; Hypnotics and

2013
Antidepressant effect of the first electroconvulsive therapy with ketamine and/or propofol.
    The journal of ECT, 2013, Volume: 29, Issue:2

    Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Depressive Disorder, Major; Electroconvulsive T

2013
Antidepressant effect of the first electroconvulsive therapy with ketamine and/or propofol: response.
    The journal of ECT, 2013, Volume: 29, Issue:2

    Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Depressive Disorder, Major; Electroconvulsive T

2013
A retrospective comparison of the effects of propofol and etomidate on stimulus variables and efficacy of electroconvulsive therapy in depressed inpatients.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Aug-01, Volume: 45

    Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Depressive Disorder, Major; Electroconvulsive The

2013
Postictal agitation after electroconvulsive therapy: incidence, severity, and propofol as a treatment option.
    The journal of ECT, 2013, Volume: 29, Issue:3

    Topics: Adult; Age Factors; Anesthesia; Anesthesia Recovery Period; Depressive Disorder, Major; Electroconvu

2013
Effects of propofol and ketamine as combined anesthesia for electroconvulsive therapy in patients with depressive disorder: a perspective from anesthesiologists.
    The journal of ECT, 2013, Volume: 29, Issue:3

    Topics: Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Cognition; D

2013
Relationship between blood levels of propofol and recovery of memory in electroconvulsive therapy.
    Psychiatry and clinical neurosciences, 2014, Volume: 68, Issue:4

    Topics: Adult; Aged; Anesthetics, Intravenous; Depressive Disorder, Major; Electroconvulsive Therapy; Female

2014
Etomidate-Induced Convulsions During Electroconvulsive Therapy: Two Case Reports.
    The journal of ECT, 2016, Volume: 32, Issue:1

    Topics: Depressive Disorder, Major; Electroconvulsive Therapy; Electroencephalography; Etomidate; Humans; Hy

2016
Identification of predictors of post-ictal delirium after electroconvulsive therapy.
    Psychiatry and clinical neurosciences, 2009, Volume: 63, Issue:2

    Topics: Adult; Anesthesia, General; Catatonia; Delirium; Depressive Disorder, Major; Electroconvulsive Thera

2009
Effect of divided supplementation of remifentanil on seizure duration and hemodynamic responses during electroconvulsive therapy under propofol anesthesia.
    Journal of anesthesia, 2011, Volume: 25, Issue:1

    Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Depressive Disorder, Major; Dose-Res

2011
A within-subject comparison of propofol and methohexital anesthesia for electroconvulsive therapy.
    The journal of ECT, 2012, Volume: 28, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Anesthetics, Intravenous; Cognition Disorde

2012
Concordance of motor and electroencephalograph (EEG) tracings in an electroconvulsive therapy (ECT) tracing: the brain-foot connection.
    The journal of ECT, 2012, Volume: 28, Issue:1

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Brain; Depressive Disorder, Major; Electroconvuls

2012
Management of poor postictal suppression during electroconvulsive therapy with propofol anesthesia: a report of two cases.
    Journal of anesthesia, 2012, Volume: 26, Issue:6

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Bipolar Disorder; Depressive Disorder, Major; Ele

2012
Remifentanil supplementation of propofol during electroconvulsive therapy: effect on seizure duration and cardiovascular stability.
    The journal of ECT, 2005, Volume: 21, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Depressive Disorder, Major; Electroconvuls

2005
Propofol for the management of emergence agitation after electroconvulsive therapy: review of a case series.
    The journal of ECT, 2006, Volume: 22, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Depressive Disorder, Major; Electroconvulsive Ther

2006
Methohexitone, propofol and etomidate in electroconvulsive therapy for depression: a naturalistic comparison study.
    Journal of affective disorders, 2009, Volume: 113, Issue:1-2

    Topics: Aged; Anesthetics, Intravenous; Depressive Disorder, Major; Electroconvulsive Therapy; Etomidate; Fe

2009
Propofol and electroconvulsive therapy in a patient at risk from acute intermittent porphyria.
    British journal of anaesthesia, 1998, Volume: 80, Issue:2

    Topics: Anesthetics, Intravenous; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Humans; Mid

1998
Efficacy and safety of venlafaxine-ECT combination in treatment-resistant depression.
    The Journal of neuropsychiatry and clinical neurosciences, 2002,Spring, Volume: 14, Issue:2

    Topics: Aged; Anesthetics, Intravenous; Antidepressive Agents, Second-Generation; Cyclohexanols; Depressive

2002