propofol has been researched along with Depression, Endogenous in 38 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The precise neural mechanisms of propofol anesthesia in humans are still unknown." | 7.72 | Neural mechanism of propofol anesthesia in severe depression: a positron emission tomographic study. ( Andoh, T; Hiroki, M; Imabayashi, E; Inoue, T; Matsuda, H; Motohashi, N; Nishikawa, M; Ogawa, K; Ohnishi, T; Takano, H; Takayama, Y; Takeda, M; Uema, T; Yamada, Y, 2003) |
| "Electroconvulsive therapy (ECT) under propofol anaesthesia induces relatively shorter seizures compared to barbiturate anaesthesia." | 5.11 | Adjustment of anaesthesia depth using bispectral index prolongs seizure duration in electroconvulsive therapy. ( Nishihara, F; Saito, S, 2004) |
| "We have studied prospectively 39 patients receiving a course of electroconvulsive therapy (ECT) for major depressive disorder; they were allocated randomly to receive either propofol or methohexitone for anaesthesia." | 5.08 | Recovery after electroconvulsive therapy: comparison of propofol with methohexitone anaesthesia. ( Beckett, WG; King, TE; Kirkby, KC; Matters, RM, 1995) |
| "In a prospective, randomised, double-blind study 20 subjects with major depressive disorder (DSM-III-R criteria) received propofol or methohexitone anaesthesia." | 5.07 | Propofol anaesthesia in electroconvulsive therapy. Reduced seizure duration may not be relevant. ( Fear, CF; Littlejohns, CS; McQuail, P; Rouse, E, 1994) |
| "BACKGROUND The present study explored the effects of propofol on hippocampal autophagy and synaptophysin in depression-model rats undergoing electroconvulsive shock (ECS)." | 3.83 | Propofol Mitigates Learning and Memory Impairment After Electroconvulsive Shock in Depressed Rats by Inhibiting Autophagy in the Hippocampus. ( Hao, XC; Li, P; Luo, J; Lv, F; Min, S; Wei, K, 2016) |
| "Recorded files of patients from the two clinics were compared in terms of ECT indications, number and duration of seizures, and anesthetic agents used (propofol vs." | 3.79 | Comparing ECT data of two different inpatient clinics: propofol or thiopental? ( Bosgelmez, S; Karabulut, U; Kirpinar, I; Tas, HI; Yazici, AB; Yazici, E; Yildiz, M, 2013) |
| "The precise neural mechanisms of propofol anesthesia in humans are still unknown." | 3.72 | Neural mechanism of propofol anesthesia in severe depression: a positron emission tomographic study. ( Andoh, T; Hiroki, M; Imabayashi, E; Inoue, T; Matsuda, H; Motohashi, N; Nishikawa, M; Ogawa, K; Ohnishi, T; Takano, H; Takayama, Y; Takeda, M; Uema, T; Yamada, Y, 2003) |
| "The dosage that was required to deeply sedate the patients, the duration of the ECT, and interval of time to full wakefulness and coherent response were measured." | 2.71 | Increased propofol requirement during succeeding administrations for electroconvulsive therapy. ( Cohen, Y; Feldinger, E; Ogorek, D; Weinbroum, AA, 2004) |
| "Postoperative confusion in the first 3 postoperative days occurred in 5 (13%) depressed patients given fentanyl during anesthesia, 13 (33%) patients without fentanyl and 1 (3%) control patients." | 2.70 | Cortisol response to surgery and postoperative confusion in depressed patients under general anesthesia with fentanyl. ( Katagai, H; Kudoh, A; Takahira, Y; Takazawa, T, 2002) |
| "We compared the duration of seizure activity and cognitive recovery profiles after different doses of methohexital, propofol, and etomidate administered to induce hypnosis prior to ECT." | 2.68 | The comparative effects of methohexital, propofol, and etomidate for electroconvulsive therapy. ( Avramov, MN; Husain, MM; White, PF, 1995) |
| "Patients with poor seizure quality may benefit from lower propofol doses, which are applicable by the addition of ketamine." | 1.62 | Empirical ratio of the combined use of S-ketamine and propofol in electroconvulsive therapy and its impact on seizure quality. ( Aksay, SS; Beuschlein, J; Bumb, JM; Janke, C; Karl, S; Kranaster, L; Pfeifer, AM; Remennik, D; Sartorius, A, 2021) |
| " Therefore, we studied whether propofol dosage had to be increased during a course of ECT." | 1.42 | No evidence for development of tolerance after repeated use of propofol for electroconvulsive therapy. ( Fischer, W; Soyka, M, 2015) |
| "The aim of this study was to compare the outcomes associated with two differing right unilateral (RUL) electroconvulsive therapy (ECT) dosing protocols: 2-3X seizure threshold (2-3X ST) and fixed high dose (FHD) at 353 mC." | 1.33 | A naturalistic comparison of two right unilateral electroconvulsive therapy dosing protocols: 2-3X seizure threshold versus fixed high-dose. ( Frost, AD; Kelly, M; Lush, P; Ward, WK, 2006) |
| "A 68-year-old male with primary aldosteronism who was scheduled for electroconvulsive therapy (ECT)." | 1.32 | [Anesthetic management for electroconvulsive therapy (ECT) in a patient with primary aldosteronism]. ( Hamaguchi, S; Kimura, Y; Kitajima, T; Nagao, M; Okuda, Y; Takanishi, T; Tezuka, M; Wake, K, 2003) |
| "The duration of seizure activity was longer in sevoflurane patients, 35 (17." | 1.32 | Anaesthesia for electroconvulsive therapy: a comparison of sevoflurane with propofol. ( Dawson, P; Hodgson, RE; Hold, AR; Rout, CC; Zuma, K, 2004) |
| "Propofol is a new anesthetic induction agent that reduces electroconvulsive therapy (ECT) seizure duration." | 1.28 | Effect of the anesthetic agent propofol on hormonal responses to ECT. ( Mitchell, P; Smythe, G; Torda, T, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.63) | 18.7374 |
| 1990's | 11 (28.95) | 18.2507 |
| 2000's | 14 (36.84) | 29.6817 |
| 2010's | 11 (28.95) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Sartorius, A | 1 |
| Beuschlein, J | 1 |
| Remennik, D | 1 |
| Pfeifer, AM | 1 |
| Karl, S | 1 |
| Bumb, JM | 1 |
| Aksay, SS | 1 |
| Kranaster, L | 1 |
| Janke, C | 1 |
| Yazici, E | 1 |
| Bosgelmez, S | 1 |
| Tas, HI | 1 |
| Karabulut, U | 1 |
| Yazici, AB | 1 |
| Yildiz, M | 1 |
| Kirpinar, I | 1 |
| Lv, F | 2 |
| Shen, YW | 1 |
| Peng, LH | 1 |
| Li, P | 2 |
| Luo, J | 3 |
| Wei, K | 2 |
| Li, W | 1 |
| Chen, J | 1 |
| Min, S | 4 |
| Soehle, M | 1 |
| Kayser, S | 1 |
| Ellerkmann, RK | 1 |
| Schlaepfer, TE | 1 |
| Soyka, M | 1 |
| Fischer, W | 1 |
| Liu, G | 1 |
| Liu, C | 1 |
| Zhang, XN | 1 |
| Zhang, F | 2 |
| Ren, L | 2 |
| Qin, P | 2 |
| Hao, X | 1 |
| Zhu, X | 1 |
| Hao, XC | 1 |
| Zhong, X | 1 |
| He, H | 1 |
| Zhang, C | 1 |
| Wang, Z | 1 |
| Jiang, M | 1 |
| Li, Q | 1 |
| Zhang, M | 1 |
| Huang, X | 1 |
| Matsura, M | 1 |
| Fujiwara, Y | 1 |
| Ito, H | 1 |
| Kandatsu, N | 1 |
| Kato, N | 1 |
| Harada, J | 1 |
| Komatsu, T | 1 |
| Gallegos, J | 1 |
| Vaidya, P | 1 |
| D'Agati, D | 1 |
| Jayaram, G | 1 |
| Nguyen, T | 1 |
| Tripathi, A | 1 |
| Trivedi, JK | 1 |
| Reti, IM | 1 |
| Kudoh, A | 1 |
| Takahira, Y | 1 |
| Katagai, H | 1 |
| Takazawa, T | 1 |
| Ogawa, K | 1 |
| Uema, T | 1 |
| Motohashi, N | 1 |
| Nishikawa, M | 1 |
| Takano, H | 1 |
| Hiroki, M | 1 |
| Imabayashi, E | 1 |
| Ohnishi, T | 1 |
| Inoue, T | 2 |
| Takayama, Y | 1 |
| Takeda, M | 1 |
| Matsuda, H | 1 |
| Andoh, T | 1 |
| Yamada, Y | 1 |
| Tezuka, M | 1 |
| Kimura, Y | 1 |
| Nagao, M | 1 |
| Wake, K | 1 |
| Takanishi, T | 1 |
| Hamaguchi, S | 1 |
| Okuda, Y | 1 |
| Kitajima, T | 1 |
| Wajima, Z | 1 |
| Shiga, T | 1 |
| Yoshikawa, T | 1 |
| Ogura, A | 1 |
| Ogawa, R | 1 |
| Ozcan, MS | 1 |
| Gravenstein, D | 1 |
| Butterfield, NN | 1 |
| Graf, P | 1 |
| Macleod, BA | 1 |
| Ries, CR | 1 |
| Zis, AP | 1 |
| Beresford, BJ | 1 |
| Glick, D | 1 |
| Dinwiddie, SH | 1 |
| Cohen, Y | 1 |
| Feldinger, E | 1 |
| Ogorek, D | 1 |
| Weinbroum, AA | 1 |
| Nishihara, F | 1 |
| Saito, S | 1 |
| McDaniel, WW | 1 |
| Hodgson, RE | 1 |
| Dawson, P | 1 |
| Hold, AR | 1 |
| Rout, CC | 1 |
| Zuma, K | 1 |
| Ward, WK | 1 |
| Lush, P | 1 |
| Kelly, M | 1 |
| Frost, AD | 1 |
| Prieto Martin, RM | 1 |
| Palomero Rodriguez, MA | 1 |
| de Miguel Fernandez, P | 1 |
| Yusta Martin, G | 1 |
| Alonso Borrego, B | 1 |
| Muriel Villoria, C | 1 |
| Kirkby, KC | 2 |
| Beckett, WG | 2 |
| Matters, RM | 2 |
| King, TE | 2 |
| Avramov, MN | 1 |
| Husain, MM | 3 |
| White, PF | 3 |
| Malsch, E | 1 |
| Gratz, I | 1 |
| Mani, S | 1 |
| Backup, C | 1 |
| Levy, S | 1 |
| Allen, E | 1 |
| Fear, CF | 2 |
| Littlejohns, CS | 2 |
| Rouse, E | 1 |
| McQuail, P | 1 |
| Fredman, B | 2 |
| d'Etienne, J | 1 |
| Smith, I | 1 |
| Mårtensson, B | 1 |
| Bartfai, A | 1 |
| Hallén, B | 1 |
| Hellström, C | 1 |
| Junthé, T | 1 |
| Olander, M | 1 |
| Rouse, EC | 1 |
| García-Toro, M | 1 |
| Segura, C | 1 |
| González, A | 1 |
| Perelló, J | 1 |
| Valdivia, J | 1 |
| Salazar, R | 1 |
| Tarancón, G | 1 |
| Campoamor, F | 1 |
| Salva, J | 1 |
| De La Fuente, L | 1 |
| Romera, M | 1 |
| Mitchell, P | 2 |
| Torda, T | 2 |
| Hickie, I | 1 |
| Burke, C | 1 |
| Smythe, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Bilateral Bispectral Index Monitoring During and After Electroconvulsive Therapy Compared With Magnetic Seizure Therapy for Treatment-resistant Depression[NCT01318018] | 20 participants (Actual) | Observational | 2011-02-28 | Completed | |||
| Same-patient Reproducibility of Intraoperative M-Entropy Measurements[NCT00599066] | 24 participants (Actual) | Observational | 2007-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
recovery time from seizure induction to eye opening / restoration of breathing (NCT01318018)
Timeframe: same day
| Intervention | minutes (Mean) |
|---|---|
| Magnetic Seizure Therapy Group | 3.0 |
| Electroconvulsive Therapy Group | 6.7 |
1 review available for propofol and Depression, Endogenous
| Article | Year |
|---|---|
Decreasing adverse outcomes of unmodified electroconvulsive therapy: suggestions and possibilities.
Topics: Anesthesia; Anesthetics, Intravenous; Anxiety; Benzodiazepines; Confusion; Depressive Disorder; Deve | 2012 |
16 trials available for propofol and Depression, Endogenous
| Article | Year |
|---|---|
Mood and neuropsychological effects of different doses of ketamine in electroconvulsive therapy for treatment-resistant depression.
Topics: Adolescent; Adult; Affect; Aged; Anesthetics, Intravenous; Cognition Disorders; Combined Modality Th | 2016 |
Prolongation of QT interval induced by electroconvulsive therapy is attenuated by landiolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Anti-Ar | 2010 |
Cortisol response to surgery and postoperative confusion in depressed patients under general anesthesia with fentanyl.
Topics: Adrenocorticotropic Hormone; Adult; Anesthesia, General; Anesthetics, Intravenous; Case-Control Stud | 2002 |
Propofol alone, sevoflurane alone, and combined propofol-sevoflurane anaesthesia in electroconvulsive therapy.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthetics, Inhalation; Blood Pressure; | 2003 |
Propofol reduces cognitive impairment after electroconvulsive therapy.
Topics: Adult; Anesthetics, Intravenous; Cognition Disorders; Cross-Over Studies; Depressive Disorder; Doubl | 2004 |
Increased propofol requirement during succeeding administrations for electroconvulsive therapy.
Topics: Ambulatory Care; Anesthetics, Intravenous; Cohort Studies; Depressive Disorder; Dose-Response Relati | 2004 |
Adjustment of anaesthesia depth using bispectral index prolongs seizure duration in electroconvulsive therapy.
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Barbiturates; Depressive Disorder; | 2004 |
Comparison of propofol and methohexitone in anaesthesia for ECT: effect on seizure duration and outcome.
Topics: Adult; Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Depressive Diso | 1995 |
Recovery after electroconvulsive therapy: comparison of propofol with methohexitone anaesthesia.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intrav | 1995 |
The comparative effects of methohexital, propofol, and etomidate for electroconvulsive therapy.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Anesthetics, Intravenous; Cross-Over Studie | 1995 |
Efficacy of electroconvulsive therapy after propofol and methohexital anesthesia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthesia, Intravenous; Depressive | 1994 |
Propofol anaesthesia in electroconvulsive therapy. Reduced seizure duration may not be relevant.
Topics: Anesthesia; Depressive Disorder; Double-Blind Method; Electroconvulsive Therapy; Humans; Propofol; P | 1994 |
Anesthesia for electroconvulsive therapy: effects of propofol and methohexital on seizure activity and recovery.
Topics: Anesthesia; Depressive Disorder; Electroconvulsive Therapy; Hemodynamics; Humans; Methohexital; Midd | 1994 |
A comparison of propofol and methohexital as anesthetic agents for ECT: effects on seizure duration, therapeutic outcome, and memory.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, General; Arousal; Bipolar Di | 1994 |
Propofol and ECT.
Topics: Anesthesia, General; Depressive Disorder; Electroconvulsive Therapy; Electroencephalography; Humans; | 1993 |
Inefficacy of burst-suppression anesthesia in medication-resistant major depression: a controlled trial.
Topics: Adult; Anesthesia; Anesthetics, Intravenous; Antidepressive Agents; Depressive Disorder; Double-Blin | 2001 |
21 other studies available for propofol and Depression, Endogenous
| Article | Year |
|---|---|
Empirical ratio of the combined use of S-ketamine and propofol in electroconvulsive therapy and its impact on seizure quality.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia; Anesthetics, Intravenous; Depressive Disorde | 2021 |
Comparing ECT data of two different inpatient clinics: propofol or thiopental?
Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Bipolar Disorder; Bra | 2013 |
Effects of propofol on expression of hippocampal neuronal nitric oxide synthase and carboxy-terminal PDZ ligand of neuronal nitric oxide synthase in stressed rats undergoing electroconvulsive shock.
Topics: Adaptor Proteins, Signal Transducing; Animals; Depressive Disorder; Disease Models, Animal; Electros | 2013 |
Bilateral bispectral index monitoring during and after electroconvulsive therapy compared with magnetic seizure therapy for treatment-resistant depression.
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Consciou | 2014 |
No evidence for development of tolerance after repeated use of propofol for electroconvulsive therapy.
Topics: Adult; Aged; Depressive Disorder; Dose-Response Relationship, Drug; Electroconvulsive Therapy; Femal | 2015 |
Comparison of the neuropsychological mechanisms of 2,6-diisopropylphenol and N-methyl-D-aspartate receptor antagonist against electroconvulsive therapy-induced learning and memory impairment in depressed rats.
Topics: Animals; Depressive Disorder; Dizocilpine Maleate; Electroconvulsive Therapy; Excitatory Amino Acid | 2015 |
Propofol alleviates electroconvulsive shock-induced memory impairment by modulating proBDNF/mBDNF ratio in depressive rats.
Topics: Anesthetics, Intravenous; Animals; Brain-Derived Neurotrophic Factor; Depressive Disorder; Disease M | 2016 |
Propofol ameliorates electroconvulsive shock-induced learning and memory impairment by regulation of synaptic metaplasticity via autophosphorylation of CaMKIIa at Thr 305 in stressed rats.
Topics: Animals; Calcium-Binding Proteins; Carrier Proteins; Depression; Depressive Disorder; Electroconvuls | 2016 |
Propofol Mitigates Learning and Memory Impairment After Electroconvulsive Shock in Depressed Rats by Inhibiting Autophagy in the Hippocampus.
Topics: Animals; Autophagy; Depression; Depressive Disorder; Disease Models, Animal; Electroconvulsive Thera | 2016 |
Neural mechanism of propofol anesthesia in severe depression: a positron emission tomographic study.
Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Blood Flow Velocity; Brain; Brain Mapping; Cerebr | 2003 |
[Anesthetic management for electroconvulsive therapy (ECT) in a patient with primary aldosteronism].
Topics: Aged; Aldosterone; Anesthesia, General; Depressive Disorder; Electroconvulsive Therapy; Humans; Hype | 2003 |
The presence of working memory without explicit recall in a critically ill patient.
Topics: Adolescent; Anesthesia, General; Anesthetics, Intravenous; Critical Illness; Depressive Disorder; El | 2004 |
Combination propofol-alfentanil anesthesia for electroconvulsive therapy in patients receiving monoamine oxidase inhibitors.
Topics: Adult; Alfentanil; Anesthetics, Intravenous; Depressive Disorder; Drug Interactions; Drug Therapy, C | 2004 |
Ketamine associated with improved memory function after ECT.
Topics: Anesthetics, Intravenous; Cognition Disorders; Depressive Disorder; Electroconvulsive Therapy; Human | 2004 |
Anaesthesia for electroconvulsive therapy: a comparison of sevoflurane with propofol.
Topics: Adult; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Case-Control Studies; Depressi | 2004 |
A naturalistic comparison of two right unilateral electroconvulsive therapy dosing protocols: 2-3X seizure threshold versus fixed high-dose.
Topics: Adult; Anesthetics; Bipolar Disorder; Clinical Protocols; Depressive Disorder; Dose-Response Relatio | 2006 |
[Electroconvulsive therapy in the third trimester of pregnancy: a case report].
Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Antidepressive Agents | 2006 |
Anaesthesia for electroconvulsive therapy: use of propofol revisited.
Topics: Adult; Aged; Anesthesia, Intravenous; Bipolar Disorder; Depressive Disorder; Dose-Response Relations | 1994 |
Propofol as an anaesthetic agent for ECT: effect on outcome and length of course.
Topics: Adult; Aged; Anesthesia, Intravenous; Cerebral Cortex; Depressive Disorder; Electroconvulsive Therap | 1991 |
Effect of the anesthetic agent propofol on hormonal responses to ECT.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Anesthesia, Intravenous; Arousal; Depressive Disorder; Ele | 1990 |
Failure to convulse with ECT.
Topics: Anesthetics; Depressive Disorder; Electroconvulsive Therapy; Humans; Male; Middle Aged; Phenols; Pro | 1989 |