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propofol and Delayed Effects, Prenatal Exposure

propofol has been researched along with Delayed Effects, Prenatal Exposure in 12 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
" Our previous studies demonstrated that maternal exposure to propofol during late stages of pregnancy impaired learning and memory in rat offspring."7.83Propofol exposure during late stages of pregnancy impairs learning and memory in rat offspring via the BDNF-TrkB signalling pathway. ( Feng, Y; Lin, J; Liu, T; Luo, F; Wang, S; Wu, L; You, X; Zhang, W; Zhao, W; Zhong, L, 2016)
"A woman who suffered an intracerebral haemorrhage secondary to Moyamoya disease in her 33rd week of pregnancy was sedated for ventilation with propofol for 48 h until she underwent emergency Caesarean section."7.69The effect of propofol sedation in pregnancy on neonatal condition. ( Bacon, RC; Razis, PA, 1994)
"Propofol is an intravenous anesthetic agent commonly used for the sedation of mechanically ventilated patients and is the only sedative agent that carries a pregnancy category B rating."4.86Prolonged propofol use in a critically ill pregnant patient. ( Bruno, JJ; Tajchman, SK, 2010)
" Our previous studies demonstrated that maternal exposure to propofol during late stages of pregnancy impaired learning and memory in rat offspring."3.83Propofol exposure during late stages of pregnancy impairs learning and memory in rat offspring via the BDNF-TrkB signalling pathway. ( Feng, Y; Lin, J; Liu, T; Luo, F; Wang, S; Wu, L; You, X; Zhang, W; Zhao, W; Zhong, L, 2016)
"To assess transplacental passage of propofol by measuring the levels in maternal and foetal plasma, and the possible relationship between the latter and the neonatal effects when propofol is used as an induction agent in obstetric anaesthesia for performing a caesarean section to terminate pregnancy."3.70Placental transfer and neonatal effects of propofol in caesarean section. ( Laguarda, M; Quintana, MB; Sánchez-Alcaraz, A, 1998)
"A woman who suffered an intracerebral haemorrhage secondary to Moyamoya disease in her 33rd week of pregnancy was sedated for ventilation with propofol for 48 h until she underwent emergency Caesarean section."3.69The effect of propofol sedation in pregnancy on neonatal condition. ( Bacon, RC; Razis, PA, 1994)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's1 (8.33)29.6817
2010's9 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, L2
Wang, S3
Feng, Y3
Zhao, W5
Zuo, W2
Zhong, L2
Lin, J3
Luo, F3
Feng, N1
Chen, D1
Qi, X1
Zhuang, R1
Cao, J1
Xu, Y1
Huang, X1
Li, Y1
Gluncic, V1
Moric, M1
Chu, Y1
Hanko, V1
Li, J2
Lukić, IK1
Lukić, A1
Edassery, SL1
Kroin, JS1
Persons, AL1
Perry, P1
Kelly, L1
Shiveley, TJ1
Nice, K1
Napier, TC1
Kordower, JH1
Tuman, KJ1
Van der Veeken, L1
Van der Merwe, J1
Devroe, S1
Inversetti, A1
Galgano, A1
Bleeser, T1
Meeusen, R1
Rex, S1
Deprest, J1
Creeley, C1
Dikranian, K1
Dissen, G1
Martin, L1
Olney, J1
Brambrink, A1
Xiong, M1
Nadavaluru, PR1
Ye, JH1
Eloy, JD1
Bekker, A1
Liu, T1
You, X1
Zhang, W1
Tajchman, SK1
Bruno, JJ1
Bacon, RC1
Razis, PA1
Sánchez-Alcaraz, A1
Quintana, MB1
Laguarda, M1

Reviews

1 review available for propofol and Delayed Effects, Prenatal Exposure

ArticleYear
Prolonged propofol use in a critically ill pregnant patient.
    The Annals of pharmacotherapy, 2010, Volume: 44, Issue:12

    Topics: Abortion, Induced; Adult; Anesthetics, Intravenous; Animals; Child; Critical Illness; Female; Humans

2010

Other Studies

11 other studies available for propofol and Delayed Effects, Prenatal Exposure

ArticleYear
KIF17 mediates the learning and memory impairment in offspring induced by maternal exposure to propofol during middle pregnancy.
    Molecular medicine reports, 2018, Volume: 17, Issue:4

    Topics: Animals; Biomarkers; Disease Models, Animal; Female; Hippocampus; Kinesins; Learning Disabilities; M

2018
Propofol exposure during early gestation impairs learning and memory in rat offspring by inhibiting the acetylation of histone.
    Journal of cellular and molecular medicine, 2018, Volume: 22, Issue:5

    Topics: Acetylation; Anesthesia; Animals; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Drug

2018
Prenatal propofol exposure downregulates NMDA receptor expression and causes cognitive and emotional disorders in rats.
    European journal of pharmacology, 2019, Jan-15, Volume: 843

    Topics: Anesthetics, Intravenous; Animals; Cognition; Down-Regulation; Female; Hypnotics and Sedatives; Mate

2019
In utero Exposure to Anesthetics Alters Neuronal Migration Pattern in Developing Cerebral Cortex and Causes Postnatal Behavioral Deficits in Rats.
    Cerebral cortex (New York, N.Y. : 1991), 2019, 12-17, Volume: 29, Issue:12

    Topics: Anesthetics; Animals; Behavior, Animal; Cell Movement; Female; Fetal Development; Isoflurane; Neurog

2019
Maternal surgery during pregnancy has a transient adverse effect on the developing fetal rabbit brain.
    American journal of obstetrics and gynecology, 2019, Volume: 221, Issue:4

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis;

2019
Propofol-induced apoptosis of neurones and oligodendrocytes in fetal and neonatal rhesus macaque brain.
    British journal of anaesthesia, 2013, Volume: 110 Suppl 1

    Topics: Anesthetics, Intravenous; Animals; Animals, Newborn; Apoptosis; Brain; Female; Macaca mulatta; Neuro

2013
Dexmedetomidine Attenuates Neurotoxicity Induced by Prenatal Propofol Exposure.
    Journal of neurosurgical anesthesiology, 2016, Volume: 28, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Blotting, Western; Brain; Calcium-Binding Proteins; Caspase 3; De

2016
Propofol exposure during late stages of pregnancy impairs learning and memory in rat offspring via the BDNF-TrkB signalling pathway.
    Journal of cellular and molecular medicine, 2016, Volume: 20, Issue:10

    Topics: Animals; Animals, Newborn; Blood Gas Analysis; Brain-Derived Neurotrophic Factor; Down-Regulation; F

2016
Pediatric emergency medicine: legal briefs.
    Pediatric emergency care, 2007, Volume: 23, Issue:3

    Topics: Acidosis; Administration, Cutaneous; Adult; Asphyxia; Brain Damage, Chronic; Burns, Chemical; Child;

2007
The effect of propofol sedation in pregnancy on neonatal condition.
    Anaesthesia, 1994, Volume: 49, Issue:12

    Topics: Adult; Cesarean Section; Conscious Sedation; Female; Humans; Infant, Newborn; Infant, Premature; Mat

1994
Placental transfer and neonatal effects of propofol in caesarean section.
    Journal of clinical pharmacy and therapeutics, 1998, Volume: 23, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Anesthetics, Intravenous; Apgar Score; Cesarean Section; Female; Hum

1998