propofol has been researched along with Critical Illness in 176 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among mechanically ventilated adults with sepsis who were being treated with recommended light-sedation approaches, outcomes in patients who received dexmedetomidine did not differ from outcomes in those who received propofol." | 9.41 | Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis. ( Anzueto, A; Bernard, GR; Brummel, NE; Bui, LN; Devlin, JW; Dittus, RS; Duprey, MS; Ely, EW; Girard, TD; Gropper, MA; Guntupalli, KK; Hoskins, AS; Hughes, CG; Jackson, JC; Kiehl, AL; Mailloux, PT; O'Neal, HR; Orun, OM; Pandharipande, PP; Patel, MB; Pun, BT; Raman, R; Sanders, RD; Snyder, A; Stashenko, GJ; Stollings, JL; Swan, JT, 2021) |
| "To determine the dose and cardiopulmonary effects of propofol alone or with midazolam for induction of anesthesia in American Society of Anesthesiologists status ≥III dogs requiring emergency abdominal surgery." | 9.34 | Dose and cardiopulmonary effects of propofol alone or with midazolam for induction of anesthesia in critically ill dogs. ( Aguilera, R; Bateman, S; Hanna, B; Sinclair, M; Valverde, A, 2020) |
| "Remifentanil was a μ-agonist, with a rapid onset, a powerful narcotic analgesic activity and a fast nonspecific esterases hydrolyzation and theoretically an ideal opioid for percutaneous dilatational tracheostomy (PDT)." | 9.30 | The use of remifentanil in critically ill patients undergoing percutaneous dilatational tracheostomy: A prospective randomized-controlled trial. ( Chang, SY; Feng, M; Liu, G; Sun, RQ; Wang, HL; Xu, DQ; Xu, YM, 2019) |
| "Dexmedetomidine is associated with less delirium than benzodiazepines and better sleep architecture than either benzodiazepines or propofol; its effect on delirium and sleep when administered at night to patients requiring sedation remains unclear." | 9.27 | Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial. ( Devlin, JW; Duprey, MS; Hill, NS; Skrobik, Y, 2018) |
| "The Basel ProDex Study is an investigator-initiated, one-institutional, two-centre randomised controlled clinical trial for the treatment of delirium with dexmedetomidine versus propofol in 316 critically ill patients suffering from hyperactive and mixed delirium." | 9.24 | Comparison of propofol and dexmedetomidine infused overnight to treat hyperactive and mixed ICU delirium: a protocol for the Basel ProDex clinical trial. ( Blum, A; Gantner, L; Hollinger, A; Ledergerber, K; Marsch, S; Rüegg, S; Siegemund, M; Steiner, LA; Sutter, R; von Felten, S; Zimmermann, S, 2017) |
| "This trial evaluated the efficacy of acetaminophen in reducing oxidative injury, as measured by plasma F2-isoprostanes, in adult patients with severe sepsis and detectable plasma cell-free hemoglobin." | 9.20 | Randomized, placebo-controlled trial of acetaminophen for the reduction of oxidative injury in severe sepsis: the Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis trial. ( Bastarache, JA; Bernard, GR; Janz, DR; Oates, JA; Rice, TW; Roberts, LJ; Sills, G; Ware, LB; Warren, MA; Wickersham, N, 2015) |
| "To observe the effects of sedation with midazolam and propofol on anterograde amnesia in critical patients." | 9.13 | [Effects of combination of midazolam and propofol on anterograde amnesia in critical patients]. ( Dai, TJ; Li, JQ; Li, L; Li, MQ; Liu, J; Lu, F; Mo, X; Xu, JY; Xu, YJ; Zhang, Z, 2008) |
| "Propofol infusion syndrome (PRIS) is a rare and often fatal syndrome described in critically ill children undergoing long-term propofol infusion at high doses." | 8.82 | The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. ( Candiani, A; Latronico, N; Rasulo, F; Vasile, B, 2003) |
| "A higher-than-usual resistance to standard sedation regimens in COVID-19 patients suffering from acute respiratory distress syndrome (ARDS) has led to the frequent use of the second-line anaesthetic agent ketamine." | 8.12 | Long-term ketamine infusion-induced cholestatic liver injury in COVID-19-associated acute respiratory distress syndrome. ( Andermatt, R; Bartussek, J; Buehler, PK; Camen, G; David, S; Erlebach, R; Hofmaenner, DA; Jüngst, C; Müllhaupt, B; Schuepbach, RA; Wendel-Garcia, PD, 2022) |
| "Propofol infusion syndrome is a rare condition that mainly affects critically ill patients who receive high doses of this hypnotic for a long time." | 7.96 | Propofol infusion syndrome; are high doses always required? ( Boliart de San Félix, Y; Fernández Morales, M; Sánchez Royo, E; Subirà González, A; Vila Lolo, C, 2020) |
| "Propofol infusion syndrome (PIS) is defined by arrhythmia, rhabdomyolysis, lactic acidosis, and unrecognized leads to death." | 7.80 | Propofol infusion syndrome: a lethal condition in critically injured patients eliminated by a simple screening protocol. ( Clement, LP; Croce, MA; Fabian, TC; Fischer, PE; Lee, M; Magnotti, LJ; Schroeppel, TJ; Sharpe, JP, 2014) |
| "The propofol infusion syndrome is a potentially devastating cardiovascular and metabolic derangement that has been described in both pediatric and adult patients sedated with propofol." | 7.75 | The propofol infusion syndrome: more puzzling evidence on a complex and poorly characterized disorder. ( Cremer, OL, 2009) |
| " Future controlled studies focusing on evaluating whether propofol manifests the derangements of critical illness more frequently than other sedatives will need to be large." | 7.75 | Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter study. ( Anger, KE; Arpino, PA; Barletta, JF; Devlin, JW; Fong, JJ; Gerlach, AT; Grgurich, P; Kendall, E; Kuper, PJ; Papadopoulos, S; Roberts, RJ; Ruthazer, R; Schumaker, G; Szumita, PM; Voils, SA; Xamplas, R; Yogaratnam, D, 2009) |
| "Propofol is a sedative, anesthetic, and antiepileptic agent that is frequently used in patients with refractory status epilepticus." | 7.75 | Propofol infusion syndrome in patients with refractory status epilepticus: an 11-year clinical experience. ( Hoel, R; Iyer, VN; Rabinstein, AA, 2009) |
| "The aim of this study was to find the optimum dosage of dexmedetomidine in Spinal Orthopedic Scoliosis Correction Surgery when used in combination with propofol and remifentanil in American Society of Anesthesiologists (ASA) III patients with severe scoliosis undergoing intraoperative wake-up test." | 5.51 | Dexmedetomidine dosage in critically ill patients undergoing intraoperative wake-up test: A randomized controlled trial. ( Chen, T; Fu, Q; Jia, H; Liu, B; Mudabbar, MS; Yang, T, 2022) |
| "Among mechanically ventilated adults with sepsis who were being treated with recommended light-sedation approaches, outcomes in patients who received dexmedetomidine did not differ from outcomes in those who received propofol." | 5.41 | Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis. ( Anzueto, A; Bernard, GR; Brummel, NE; Bui, LN; Devlin, JW; Dittus, RS; Duprey, MS; Ely, EW; Girard, TD; Gropper, MA; Guntupalli, KK; Hoskins, AS; Hughes, CG; Jackson, JC; Kiehl, AL; Mailloux, PT; O'Neal, HR; Orun, OM; Pandharipande, PP; Patel, MB; Pun, BT; Raman, R; Sanders, RD; Snyder, A; Stashenko, GJ; Stollings, JL; Swan, JT, 2021) |
| " However, the relative contributions of propofol use and critical illness itself to burst suppression; of burst suppression, propofol, and critical illness to mortality; and whether preventing burst suppression might reduce mortality, have not been quantified." | 5.34 | Burst Suppression: Causes and Effects on Mortality in Critical Illness. ( Aboul Nour, H; Akeju, O; Bordbar, E; Cole, AJ; Edhi, MM; Gallagher, J; Ghanta, M; Hogan, J; Javed, F; Jing, J; Junior, VM; Kassa, S; Rosenthal, ES; Shao, YP; Shoukat, M; Sun, H; Tabaeizadeh, M; Westover, MB; Zafar, S, 2020) |
| "To determine the dose and cardiopulmonary effects of propofol alone or with midazolam for induction of anesthesia in American Society of Anesthesiologists status ≥III dogs requiring emergency abdominal surgery." | 5.34 | Dose and cardiopulmonary effects of propofol alone or with midazolam for induction of anesthesia in critically ill dogs. ( Aguilera, R; Bateman, S; Hanna, B; Sinclair, M; Valverde, A, 2020) |
| "Remifentanil was a μ-agonist, with a rapid onset, a powerful narcotic analgesic activity and a fast nonspecific esterases hydrolyzation and theoretically an ideal opioid for percutaneous dilatational tracheostomy (PDT)." | 5.30 | The use of remifentanil in critically ill patients undergoing percutaneous dilatational tracheostomy: A prospective randomized-controlled trial. ( Chang, SY; Feng, M; Liu, G; Sun, RQ; Wang, HL; Xu, DQ; Xu, YM, 2019) |
| "Dexmedetomidine is associated with less delirium than benzodiazepines and better sleep architecture than either benzodiazepines or propofol; its effect on delirium and sleep when administered at night to patients requiring sedation remains unclear." | 5.27 | Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial. ( Devlin, JW; Duprey, MS; Hill, NS; Skrobik, Y, 2018) |
| "The Basel ProDex Study is an investigator-initiated, one-institutional, two-centre randomised controlled clinical trial for the treatment of delirium with dexmedetomidine versus propofol in 316 critically ill patients suffering from hyperactive and mixed delirium." | 5.24 | Comparison of propofol and dexmedetomidine infused overnight to treat hyperactive and mixed ICU delirium: a protocol for the Basel ProDex clinical trial. ( Blum, A; Gantner, L; Hollinger, A; Ledergerber, K; Marsch, S; Rüegg, S; Siegemund, M; Steiner, LA; Sutter, R; von Felten, S; Zimmermann, S, 2017) |
| "Dexmedetomidine did not significantly impact ICU length of stay compared with propofol, but it significantly reduced the duration of mechanical ventilation and the risk of delirium in cardiac surgical patients." | 5.22 | Outcomes of dexmedetomidine versus propofol sedation in critically ill adults requiring mechanical ventilation: a systematic review and meta-analysis of randomised controlled trials. ( Ali, S; Deng, J; Heybati, K; Mohananey, D; Ramakrishna, H; Villablanca, P; Zhou, F, 2022) |
| "This trial evaluated the efficacy of acetaminophen in reducing oxidative injury, as measured by plasma F2-isoprostanes, in adult patients with severe sepsis and detectable plasma cell-free hemoglobin." | 5.20 | Randomized, placebo-controlled trial of acetaminophen for the reduction of oxidative injury in severe sepsis: the Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis trial. ( Bastarache, JA; Bernard, GR; Janz, DR; Oates, JA; Rice, TW; Roberts, LJ; Sills, G; Ware, LB; Warren, MA; Wickersham, N, 2015) |
| "To observe the effects of sedation with midazolam and propofol on anterograde amnesia in critical patients." | 5.13 | [Effects of combination of midazolam and propofol on anterograde amnesia in critical patients]. ( Dai, TJ; Li, JQ; Li, L; Li, MQ; Liu, J; Lu, F; Mo, X; Xu, JY; Xu, YJ; Zhang, Z, 2008) |
| "Propofol is an intravenous anesthetic agent commonly used for the sedation of mechanically ventilated patients and is the only sedative agent that carries a pregnancy category B rating." | 4.86 | Prolonged propofol use in a critically ill pregnant patient. ( Bruno, JJ; Tajchman, SK, 2010) |
| "Propofol infusion syndrome (PRIS) is a rare and often fatal syndrome described in critically ill children undergoing long-term propofol infusion at high doses." | 4.82 | The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. ( Candiani, A; Latronico, N; Rasulo, F; Vasile, B, 2003) |
| "The majority of cases (8/11) are related to propofol use leading to hypertriglyceridemia." | 4.31 | Hypertriglyceridemia as a Cause of Continuous Renal Replacement Therapy Circuit Clotting: A Case Series. ( Abo-Zed, A; Abramovitz, BW; DeSilva, R; Oguntuwase, E, 2023) |
| "A higher-than-usual resistance to standard sedation regimens in COVID-19 patients suffering from acute respiratory distress syndrome (ARDS) has led to the frequent use of the second-line anaesthetic agent ketamine." | 4.12 | Long-term ketamine infusion-induced cholestatic liver injury in COVID-19-associated acute respiratory distress syndrome. ( Andermatt, R; Bartussek, J; Buehler, PK; Camen, G; David, S; Erlebach, R; Hofmaenner, DA; Jüngst, C; Müllhaupt, B; Schuepbach, RA; Wendel-Garcia, PD, 2022) |
| "For endotracheal suctioning, NFR, BPS, CPOT and RASS showed predictive performances significantly better than chance, but none of them performed significantly better than the sufentanil dose rate." | 4.12 | Investigation of Behavioural Pain Scale, Critical Care Pain Observation Tool, nociceptive flexion reflex and pupillary dilatation reflex as predictors of behavioural reactions to nociceptive procedures in critically ill patients unable to self-report pain ( Bublitz, VK; Jurth, C; Lezius, F; Lichtner, G; Schaaf, L; von Dincklage, F; Zimmermann, V, 2022) |
| "Propofol infusion syndrome is a rare condition that mainly affects critically ill patients who receive high doses of this hypnotic for a long time." | 3.96 | Propofol infusion syndrome; are high doses always required? ( Boliart de San Félix, Y; Fernández Morales, M; Sánchez Royo, E; Subirà González, A; Vila Lolo, C, 2020) |
| "To compare the development of clinically significant hemodynamic event (ie, hypotension or bradycardia) in adults with septic shock receiving either propofol or dexmedetomidine." | 3.96 | Effects From Continuous Infusions of Dexmedetomidine and Propofol on Hemodynamic Stability in Critically Ill Adult Patients With Septic Shock. ( Hammond, DA; Nelson, KM; Patel, GP, 2020) |
| "Propofol infusion syndrome (PIS) is defined by arrhythmia, rhabdomyolysis, lactic acidosis, and unrecognized leads to death." | 3.80 | Propofol infusion syndrome: a lethal condition in critically injured patients eliminated by a simple screening protocol. ( Clement, LP; Croce, MA; Fabian, TC; Fischer, PE; Lee, M; Magnotti, LJ; Schroeppel, TJ; Sharpe, JP, 2014) |
| "Higher doses of dexmedetomidine may result in higher incidence of hypotension, longer LOS, and increased concomitant analgesic, sedative, and antipsychotic use, requiring further evaluation in trauma patients." | 3.77 | Evaluation of dexmedetomidine: safety and clinical outcomes in critically ill trauma patients. ( Devabhakthuni, S; Kufera, JA; Pajoumand, M; Stein, DM; Watson, K; Williams, C, 2011) |
| "Propofol is a sedative, anesthetic, and antiepileptic agent that is frequently used in patients with refractory status epilepticus." | 3.75 | Propofol infusion syndrome in patients with refractory status epilepticus: an 11-year clinical experience. ( Hoel, R; Iyer, VN; Rabinstein, AA, 2009) |
| " Future controlled studies focusing on evaluating whether propofol manifests the derangements of critical illness more frequently than other sedatives will need to be large." | 3.75 | Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter study. ( Anger, KE; Arpino, PA; Barletta, JF; Devlin, JW; Fong, JJ; Gerlach, AT; Grgurich, P; Kendall, E; Kuper, PJ; Papadopoulos, S; Roberts, RJ; Ruthazer, R; Schumaker, G; Szumita, PM; Voils, SA; Xamplas, R; Yogaratnam, D, 2009) |
| "The propofol infusion syndrome is a potentially devastating cardiovascular and metabolic derangement that has been described in both pediatric and adult patients sedated with propofol." | 3.75 | The propofol infusion syndrome: more puzzling evidence on a complex and poorly characterized disorder. ( Cremer, OL, 2009) |
| "In critical illness, patients receiving M&M for sedation are more likely to have slow gastric emptying, and proximal meal retention than those receiving propofol." | 3.74 | The effects of sedation on gastric emptying and intra-gastric meal distribution in critical illness. ( Bellon, M; Bryant, LK; Burgstad, C; Chapman, MJ; Ching, K; Fraser, RJ; Holloway, RH; Nguyen, NQ, 2008) |
| " Administration of propofol via continuous intravenous infusion was not associated with metabolic acidosis or hemodynamic compromise." | 3.71 | Continuous propofol infusion in 142 critically ill children. ( Cornfield, DN; Milla, CE; Nelson, MD; Sweeney, M; Tegtmeyer, K, 2002) |
| " However, evidence for long-term use remains low." | 3.30 | Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients - A randomized controlled trial. ( Christel, A; Kellner, P; Michel, P; Schittek, GA; Soukup, J; Wagner, NM, 2023) |
| "Periintubation hypotension is associated with poor outcomes in the critically ill." | 2.90 | Ketamine/propofol admixture vs etomidate for intubation in the critically ill: KEEP PACE Randomized clinical trial. ( Bauer, PR; Brown, DR; Gajic, O; Gallo De Moraes, A; Hoskote, SS; Iyer, VN; Nicholson, WT; Oeckler, RA; Pickering, B; Schroeder, DR; Smischney, NJ, 2019) |
| "Propofol was given to 16 of 21 (76%) of early goal-directed sedation versus 16 of 16 (100%) of standard sedation patients (p = 0." | 2.78 | Early goal-directed sedation versus standard sedation in mechanically ventilated critically ill patients: a pilot study*. ( Bailey, M; Bass, F; Bellomo, R; Howe, B; McArthur, C; Murray, L; Reade, MC; Seppelt, IM; Shehabi, Y; Webb, S; Weisbrodt, L, 2013) |
| "Propofol consumption was reduced by a factor of 2 in the automated group with a median change of infusion rates of 39 ± 9 times per hour." | 2.78 | Automated sedation outperforms manual administration of propofol and remifentanil in critically ill patients with deep sedation: a randomized phase II trial. ( Bourgeois, E; Chazot, T; Fischler, M; Le Guen, M; Liu, N; Rouby, JJ; Sessler, DI, 2013) |
| "Standard treatment of critically ill patients undergoing mechanical ventilation is continuous sedation." | 2.75 | A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial. ( Martinussen, T; Strøm, T; Toft, P, 2010) |
| " There is a lower risk of propofol infusion exceeding manufacturer's recommended dosing guides in the BIS-augmentation group versus the Ramsay-alone group (0 vs." | 2.74 | A randomized evaluation of bispectral index-augmented sedation assessment in neurological patients. ( Graffagnino, C; Olson, DM; Peterson, ED; Thoyre, SM, 2009) |
| " V was applied for propofol pharmacokinetic analysis." | 2.73 | Pilot study on the influence of liver blood flow and cardiac output on the clearance of propofol in critically ill patients. ( Aarts, LP; Boom, FA; Bras, LJ; Danhof, M; Knibbe, CA; Peeters, MY; Tibboel, D, 2008) |
| "As glycine concentration was also correlated with creatinine clearance and because remifentanil was the only source of exogenous glycine, additional data are necessary to ascertain the safety of remifentanil infusion in ICU patients." | 2.73 | Glycine and ammonia plasma concentrations during sedation with remifentanil in critically ill patients. ( Asehnoune, K; Benhamou, D; Bonnet, MP; Bridoux, D; Duranteau, J; Minville, V; Poggi-Bach, J, 2007) |
| " Both sedatives were administered over 7 days and individual dosage was adapted according to clinical requirements." | 2.72 | Effects of propofol vs methohexital on neutrophil function and immune status in critically ill patients. ( Hout, Nv; Huettemann, E; Jung, A; Sakka, SG; Vogelsang, H, 2006) |
| "Propofol 60 mg ml(-1) is a useful alternative to propofol 10 mg ml(-1) for the long-term sedation of critically ill patients." | 2.71 | Long-term sedation with propofol 60 mg ml(-1) vs. propofol 10 mg(-1) ml in critically ill, mechanically ventilated patients. ( Aarts, LP; Danhof, M; Knibbe, CA; Kuks, PF; Naber, H, 2004) |
| "The propofol formulation was not a significant covariate for the pharmacokinetics, whereas serum triglyceride concentration (TG) and relative body temperature (T(c)) were significant covariates for elimination clearance (CL)." | 2.70 | Population pharmacokinetic and pharmacodynamic modeling of propofol for long-term sedation in critically ill patients: a comparison between propofol 6% and propofol 1%. ( Aarts, LP; Danhof, M; DeJongh, J; Knibbe, CA; Kuks, PF; Zuideveld, KP, 2002) |
| " The mean number of dosage changes per day was 7." | 2.69 | Continuous infusions of lorazepam, midazolam, and propofol for sedation of the critically ill surgery trauma patient: a prospective, randomized comparison. ( Byrne, TK; McCollam, JS; Norcross, ED; O'Neil, MG; Reeves, ST, 1999) |
| "Propofol EDTA-treated patients had greater urinary losses of zinc and iron and lower serum zinc concentrations compared with the non-EDTA sedative group." | 2.69 | Trace element homeostasis during continuous sedation with propofol containing EDTA versus other sedatives in critically ill patients. ( Dedhia, HV; Fulda, G; Gelmont, D; Higgins, TL; Kett, DH; Ko, H; Kramer, KM; Levy, H; Murray, M; Teres, D; Thompson, KA; Zaloga, GP, 2000) |
| "Propofol or midazolam was used for induction and maintenance of continuous intravenous sedation for a maximum of 5 days." | 2.68 | Comparative study of propofol versus midazolam in the sedation of critically ill patients: results of a prospective, randomized, multicenter trial. ( Barrios, M; Carpintero, JL; Chamorro, C; de Latorre, FJ; Ginestal, R; Gonzalez, E; Jareño, A; Martín-Santos, F; Montero, A; Moreno, JA; Otero, B; Sánchez-Izquierdo, JA, 1996) |
| " We conclude that in this patient population: (1) both P and M achieved optimal sedation in a large fraction of patients when administered by specified dosing protocols; (2) P had a faster, more reliable, wake-up time; (3) assessments of time-to-awaken were objective and reproducible; (4) time to sedation was not significantly different; (5) V O2 decreased similarly with both." | 2.68 | Sedation of critically ill patients during mechanical ventilation. A comparison of propofol and midazolam. ( Hall, JB; Kress, JP; Lavoie, A; O'Connor, MF; Olson, D; Pohlman, AS; Toledano, A, 1996) |
| "Ketamine was not associated with mortality, on-target sedation, vasopressor dependence, or hospital length of stay." | 2.66 | Ketamine sedation in mechanically ventilated patients: A systematic review and meta-analysis. ( Fuller, BM; Manasco, AT; Roberts, BW; Stephens, RJ; Yaeger, LH, 2020) |
| "The pharmacokinetic (PK) parameters of many drugs are altered as a consequence of the pathophysiological changes associated with critical illness." | 2.58 | Altered Pharmacokinetics in Prolonged Infusions of Sedatives and Analgesics Among Adult Critically Ill Patients: A Systematic Review. ( Joynt, GM; Lee, A; Ling, L; Tse, AHW, 2018) |
| " Neuroleptic drugs can produce severe side effects and need careful dosage and monitoring." | 2.44 | [Delusion in the critical patient]. ( Palencia-Herrejón, E; Romera, MA; Silva, JA, 2008) |
| "Propofol has superior value compared with lorazepam when used for sedation among the critically ill who require mechanical ventilation when used in the setting of daily sedative interruption." | 2.44 | Economic evaluation of propofol and lorazepam for critically ill patients undergoing mechanical ventilation. ( Campbell-Bright, S; Carson, SS; Cox, CE; Govert, JA; Kress, JP; Reed, SD; Rodgers, JE, 2008) |
| " Regular evaluation of the effect of these drugs and subsequent adaptation of dosage are more important than the choice of specific analgesics and hypnotics." | 2.42 | Analgesia and sedation in critically ill patients. ( Tramèr, MR; Walder, B, 2004) |
| "Patients suffering from critical illnesses like cardiac arrest with resuscitation and hypovolemic shock often are in need of medication." | 2.41 | [Pharmacology in critical illness]. ( Buylaert, WA, 2001) |
| "Societal fears of opioid addiction and lack of advocacy are also causal factors in the under-treatment of pediatric pain." | 2.41 | Pain management in the critically ill child. ( Nichols, DG; Yaster, M, 2001) |
| "Propofol has many of the qualities of an ideal sedative agent." | 2.41 | Use of propofol and other nonbenzodiazepine sedatives in the intensive care unit. ( Angelini, G; Coursin, DB; Ketzler, JT, 2001) |
| " Inadequate doses or dosing regimens should be avoided." | 2.39 | Pharmacology of intravenous sedatives and opioids in critically ill patients. ( Levine, RL, 1994) |
| "To test the hypothesis that a pragmatic propofol-based sedation regimen with restricted polypharmacy (RP; ie, prohibits additional infusions unless a predefined propofol dosage threshold is exceeded) would increase coma-and ventilator-free days compared with usual care (UC), we performed a retrospective cohort study of adults admitted to intensive care units (ICUs) of a tertiary-level medical center who were mechanically ventilated, initiated on propofol infusion, and had >50% probability of need for continued ventilation for the next 24 hours." | 1.91 | Restricted Polypharmacy Compared to Usual Care in Mechanically Ventilated Patients: A Retrospective Cohort Study. ( Bose, S; Lehman, LW; Shahn, Z; Talmor, D, 2023) |
| "The propofol dose was comparable for each group." | 1.62 | Observational study evaluating the nutritional impact of changing from 1% to 2% propofol in a cardiothoracic adult critical care unit. ( Remmington, C; Terblanche, E, 2021) |
| "Patients with traumatic brain (TBI) injury often require a high dosage of propofol, which can provide an excessive caloric intake." | 1.62 | Improvement in Protein Delivery for Critically Ill Patients Requiring High-Dose Propofol Therapy and Enteral Nutrition. ( Buckley, CT; Dickerson, RN; Fischer, PE; Minard, G; Van Matre, ET, 2021) |
| " Adverse effect profiles and clinical outcome, in the cohorts are largely similar." | 1.56 | DEXmedetomidine compared to PROpofol in NEurocritical Care [DEXPRONE]: A multicenter retrospective evaluation of clinical utility and safety. ( Armahizer, MJ; Heavner, MS; Kurczewski, L; Maciel, CB; Owusu, KA; Zichichi, A, 2020) |
| "However, acute urinary retention is little studied among intensive care patients." | 1.51 | Incidence and risk factors for urinary retention in critically ill patients. ( Alves, JC; Bafi, AT; Freitas, FG; Machado, FR; Schettini, DA; Tomotani, DY, 2019) |
| "Mean propofol sedation dose was 2045 ± 1650 mg/d, resulting in 146 ± 117 kcal/d." | 1.46 | Propofol sedation substantially increases the caloric and lipid intake in critically ill patients. ( Berger, MM; Bianchet, O; Charrière, M; Hastings, J; Ridley, E; Scheinkestel, C, 2017) |
| "Propofol exposure may increase the risk of ICUAW in septic patients." | 1.46 | Propofol as a Risk Factor for ICU-Acquired Weakness in Septic Patients with Acute Respiratory Failure. ( Abdelmalik, PA; Rakocevic, G, 2017) |
| "Isoflurane has shown better control of intensive care sedation than propofol or midazolam and seems to be a useful alternative." | 1.43 | Survival after long-term isoflurane sedation as opposed to intravenous sedation in critically ill surgical patients: Retrospective analysis. ( Bellgardt, M; Bomberg, H; Dasch, B; Herzog-Niescery, J; Meiser, A; Steinfort, C; Uhl, W; Vogelsang, H; Volk, T; Wagenpfeil, S; Weber, TP, 2016) |
| "Propofol was the most frequently used sedative drug, followed by benzodiazepines, barbiturates, and dexmedetomidine." | 1.43 | The relationship between sedative drug utilization and outcomes in critically ill patients undergoing mechanical ventilation. ( Hayashida, K; Ikai, H; Imanaka, Y; Murakami, G; Nishimura, M; Umegaki, T, 2016) |
| "Propofol was associated with lower AKI incidence using both urine output (45." | 1.42 | Renal Outcomes in Critically Ill Patients Receiving Propofol or Midazolam. ( Leite, TT; Libório, AB; Macedo, E; Martins, Ida S; Neves, FM, 2015) |
| "Propofol was used as the sole sedative agent in 409 (87%) of the 472 patients." | 1.42 | Safety of Propofol as an Induction Agent for Urgent Endotracheal Intubation in the Medical Intensive Care Unit. ( Doelken, P; Koenig, SJ; Lakticova, V; Mayo, PH; Narasimhan, M, 2015) |
| "Analgosedation with fentanyl appears to be a safe and effective strategy to facilitate mechanical ventilation." | 1.40 | Efficacy and safety of analgosedation with fentanyl compared with traditional sedation with propofol. ( Edwin, SB; McNorton, KN; Tedders, KM, 2014) |
| " The drug dosage in combination group was decreased significantly compared with propofol group and midazolam group (total dosage of propofol: 25." | 1.39 | [Comparison of sedative effects of propofol and midazolam on emergency critical patients on mechanical ventilation]. ( Hong, GL; Lu, ZQ; Qiu, QM; Wu, B; Xu, AY; Zhao, GJ, 2013) |
| "Forty early septic shock patients were included in the study and administered either the loading dose infusion of propofol (n = 20, group P) of 1 mg/kg over 15 minutes followed by a maintenance dose of 1 to 3 mg/kg per hour (n = 20, group P), or a loading dose of dexmedetomidine 1 microg/kg over 10 minutes followed by a maintenance of 0." | 1.35 | Effects of propofol and dexmedetomidine on indocyanine green elimination assessed with LIMON to patients with early septic shock: a pilot study. ( Kargi, M; Memiş, D; Sut, N, 2009) |
| "9 days) using the Ramsay scale and the bispectral index as pharmacodynamic end points." | 1.35 | Disease severity is a major determinant for the pharmacodynamics of propofol in critically ill patients. ( Aarts, LP; Bras, LJ; Danhof, M; DeJongh, J; Knibbe, CA; Peeters, MY; Wesselink, RM, 2008) |
| "Clonidine was a common part of up to two-thirds of the regimens." | 1.33 | Practice of sedation and analgesia in German intensive care units: results of a national survey. ( Fischer, M; Franck, M; Martin, J; Parsch, A; Spies, C; Wernecke, KD, 2005) |
| "Propofol was least costly in 86% of the short-term simulations, midazolam was least costly in 97." | 1.33 | Pharmacoeconomic modeling of lorazepam, midazolam, and propofol for continuous sedation in critically ill patients. ( MacLaren, R; Sullivan, PW, 2005) |
| "Propofol has been shown to produce a predictable and easily attainable level of sedation in postcardiac, head-injured, general trauma patients." | 1.32 | Case report: requirement of supplemental morphine during sedation with propofol in a critically ill patient undergoing hemodiafiltration. ( Borrelli, LM; Gatta, G; Imperatore, F; Liguori, G; Marsilia, PF; Martino, A; Munciello, F; Occhiochiuso, L, 2003) |
| "Propofol is a lipid-based sedative that provides 1." | 1.29 | Pharmacologic influence on nutrition support therapy: use of propofol in a patient receiving combined enteral and parenteral nutrition support. ( Brown, RO; Dickerson, RN; Dunlap, AW; Kudsk, KA; Lowrey, TS, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 26 (14.77) | 18.2507 |
| 2000's | 55 (31.25) | 29.6817 |
| 2010's | 55 (31.25) | 24.3611 |
| 2020's | 40 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, H | 1 |
| Choi, S | 1 |
| Jang, EJ | 1 |
| Lee, J | 1 |
| Kim, D | 1 |
| Yoo, S | 1 |
| Oh, SY | 1 |
| Ryu, HG | 1 |
| El Nekidy, WS | 1 |
| Shatnawei, A | 1 |
| Abdelsalam, MM | 1 |
| Hassan, M | 1 |
| Dajani, RZ | 1 |
| Salem, N | 1 |
| St John, TJL | 1 |
| Rahman, N | 1 |
| Hamed, F | 1 |
| Mallat, J | 1 |
| Jiang, X | 1 |
| Yan, M | 1 |
| Viana, MV | 1 |
| Pantet, O | 1 |
| Charrière, M | 2 |
| Favre, D | 1 |
| Piquilloud, L | 1 |
| Schneider, AG | 1 |
| Hurni, CA | 1 |
| Berger, MM | 3 |
| Yang, T | 1 |
| Mudabbar, MS | 1 |
| Chen, T | 1 |
| Jia, H | 1 |
| Fu, Q | 1 |
| Liu, B | 1 |
| Zhou, Y | 2 |
| Yang, J | 1 |
| Wang, B | 1 |
| Wang, P | 1 |
| Wang, Z | 1 |
| Yang, Y | 2 |
| Liang, G | 2 |
| Jing, X | 1 |
| Jin, X | 2 |
| Zhang, Z | 2 |
| Deng, Y | 1 |
| Hu, C | 1 |
| Liao, X | 1 |
| Yin, W | 1 |
| Tang, Z | 1 |
| Tian, Y | 1 |
| Tao, L | 1 |
| Kang, Y | 2 |
| Li, P | 1 |
| Huang, Y | 2 |
| Wong, A | 1 |
| Wendel-Garcia, PD | 1 |
| Erlebach, R | 1 |
| Hofmaenner, DA | 1 |
| Camen, G | 1 |
| Schuepbach, RA | 1 |
| Jüngst, C | 1 |
| Müllhaupt, B | 1 |
| Bartussek, J | 1 |
| Buehler, PK | 1 |
| Andermatt, R | 1 |
| David, S | 1 |
| Li, WK | 1 |
| Chen, XJC | 1 |
| Altshuler, D | 1 |
| Islam, S | 1 |
| Spiegler, P | 1 |
| Emerson, L | 1 |
| Bender, M | 1 |
| Jurth, C | 1 |
| Zimmermann, V | 1 |
| Schaaf, L | 1 |
| Lezius, F | 1 |
| Bublitz, VK | 1 |
| Lichtner, G | 1 |
| von Dincklage, F | 1 |
| Heybati, K | 1 |
| Zhou, F | 1 |
| Ali, S | 1 |
| Deng, J | 1 |
| Mohananey, D | 1 |
| Villablanca, P | 1 |
| Ramakrishna, H | 1 |
| Honore, PM | 4 |
| Redant, S | 3 |
| Djimafo, P | 3 |
| Blackman, S | 4 |
| Bousbiat, I | 4 |
| Perriens, E | 4 |
| Preseau, T | 3 |
| Cismas, BV | 3 |
| Kaefer, K | 3 |
| Barreto Gutierrez, L | 3 |
| Anane, S | 3 |
| Gallerani, A | 3 |
| Attou, R | 3 |
| Moore, JPR | 3 |
| Shehabi, Y | 5 |
| Reade, MC | 5 |
| Bailey, M | 5 |
| Fraser, JF | 3 |
| Murray, L | 5 |
| Anstey, C | 3 |
| Singer, M | 3 |
| Burry, L | 2 |
| De Jong, A | 2 |
| Soukup, J | 3 |
| Michel, P | 1 |
| Christel, A | 1 |
| Schittek, GA | 1 |
| Wagner, NM | 2 |
| Kellner, P | 3 |
| Abramovitz, BW | 1 |
| Oguntuwase, E | 1 |
| Abo-Zed, A | 1 |
| DeSilva, R | 1 |
| Bose, S | 1 |
| Lehman, LW | 1 |
| Talmor, D | 1 |
| Shahn, Z | 1 |
| Sperotto, F | 1 |
| Emani, S | 1 |
| Zhu, L | 1 |
| Delgado, M | 1 |
| Santillana, M | 1 |
| Kheir, JN | 1 |
| Assadoon, MS | 1 |
| Kovacevic, MP | 1 |
| Dube, KM | 1 |
| Szumita, PM | 2 |
| Lupi, KE | 1 |
| DeGrado, JR | 1 |
| Grensemann, J | 1 |
| Gilmour, S | 1 |
| Tariparast, PA | 1 |
| Petzoldt, M | 1 |
| Kluge, S | 1 |
| Tang, Y | 1 |
| Gao, X | 1 |
| Xu, J | 1 |
| Ren, L | 1 |
| Qi, H | 1 |
| Li, R | 1 |
| Shu, H | 1 |
| Zou, X | 1 |
| Yuan, S | 1 |
| Yang, X | 1 |
| Shang, Y | 1 |
| Ho, AM | 1 |
| Mizubuti, GB | 1 |
| Georgiou, E | 1 |
| Paikousis, L | 1 |
| Lambrinou, E | 1 |
| Merkouris, A | 1 |
| Papathanassoglou, EDE | 1 |
| Manasco, AT | 1 |
| Stephens, RJ | 1 |
| Yaeger, LH | 1 |
| Roberts, BW | 1 |
| Fuller, BM | 1 |
| Olsen, HT | 1 |
| Nedergaard, HK | 1 |
| Strøm, T | 2 |
| Oxlund, J | 1 |
| Wian, KA | 1 |
| Ytrebø, LM | 1 |
| Kroken, BA | 1 |
| Chew, M | 1 |
| Korkmaz, S | 1 |
| Lauridsen, JT | 1 |
| Toft, P | 2 |
| Hogan, J | 1 |
| Sun, H | 1 |
| Aboul Nour, H | 1 |
| Jing, J | 1 |
| Tabaeizadeh, M | 1 |
| Shoukat, M | 1 |
| Javed, F | 1 |
| Kassa, S | 1 |
| Edhi, MM | 1 |
| Bordbar, E | 1 |
| Gallagher, J | 1 |
| Junior, VM | 1 |
| Ghanta, M | 1 |
| Shao, YP | 1 |
| Akeju, O | 1 |
| Cole, AJ | 1 |
| Rosenthal, ES | 1 |
| Zafar, S | 1 |
| Westover, MB | 1 |
| Subirà González, A | 1 |
| Fernández Morales, M | 1 |
| Sánchez Royo, E | 1 |
| Boliart de San Félix, Y | 1 |
| Vila Lolo, C | 1 |
| Winings, NA | 1 |
| Daley, BJ | 1 |
| Bollig, RW | 1 |
| Roberts, RF | 1 |
| Radtke, J | 1 |
| Heidel, RE | 1 |
| Taylor, JE | 1 |
| McMillen, JC | 1 |
| Payen, JF | 2 |
| Chanques, G | 1 |
| Futier, E | 1 |
| Velly, L | 1 |
| Jaber, S | 1 |
| Constantin, JM | 1 |
| Aguilera, R | 1 |
| Sinclair, M | 1 |
| Valverde, A | 1 |
| Bateman, S | 1 |
| Hanna, B | 1 |
| Buckley, CT | 1 |
| Van Matre, ET | 1 |
| Fischer, PE | 2 |
| Minard, G | 1 |
| Dickerson, RN | 2 |
| Lönnqvist, PA | 1 |
| Bell, M | 1 |
| Karlsson, T | 1 |
| Wiklund, L | 1 |
| Höglund, AS | 1 |
| Larsson, L | 1 |
| Owusu, KA | 1 |
| Kurczewski, L | 1 |
| Armahizer, MJ | 1 |
| Zichichi, A | 1 |
| Maciel, CB | 1 |
| Heavner, MS | 1 |
| Lucchetta, V | 1 |
| Bonvicini, D | 1 |
| Ballin, A | 1 |
| Tiberio, I | 1 |
| Hirota, K | 1 |
| Lambert, DG | 1 |
| Terblanche, E | 1 |
| Remmington, C | 1 |
| Hughes, CG | 1 |
| Mailloux, PT | 1 |
| Devlin, JW | 6 |
| Swan, JT | 1 |
| Sanders, RD | 1 |
| Anzueto, A | 1 |
| Jackson, JC | 1 |
| Hoskins, AS | 1 |
| Pun, BT | 1 |
| Orun, OM | 1 |
| Raman, R | 1 |
| Stollings, JL | 1 |
| Kiehl, AL | 1 |
| Duprey, MS | 2 |
| Bui, LN | 1 |
| O'Neal, HR | 1 |
| Snyder, A | 1 |
| Gropper, MA | 1 |
| Guntupalli, KK | 1 |
| Stashenko, GJ | 1 |
| Patel, MB | 1 |
| Brummel, NE | 1 |
| Girard, TD | 1 |
| Dittus, RS | 1 |
| Bernard, GR | 2 |
| Ely, EW | 1 |
| Pandharipande, PP | 1 |
| Kermad, A | 1 |
| Speltz, J | 1 |
| Danziger, G | 1 |
| Mertke, T | 1 |
| Bals, R | 1 |
| Volk, T | 2 |
| Lepper, PM | 1 |
| Meiser, A | 2 |
| Hollinger, A | 1 |
| Ledergerber, K | 1 |
| von Felten, S | 1 |
| Sutter, R | 1 |
| Rüegg, S | 1 |
| Gantner, L | 1 |
| Zimmermann, S | 1 |
| Blum, A | 1 |
| Steiner, LA | 1 |
| Marsch, S | 1 |
| Siegemund, M | 1 |
| Hastings, J | 2 |
| Ridley, EJ | 1 |
| Bianchet, O | 2 |
| Roodenburg, O | 1 |
| Levkovich, B | 1 |
| Scheinkestel, C | 2 |
| Pilcher, D | 1 |
| Udy, A | 1 |
| Ridley, E | 1 |
| Schettini, DA | 1 |
| Freitas, FG | 1 |
| Tomotani, DY | 1 |
| Alves, JC | 1 |
| Bafi, AT | 1 |
| Machado, FR | 1 |
| Skrobik, Y | 1 |
| Hill, NS | 1 |
| Tse, AHW | 1 |
| Ling, L | 1 |
| Lee, A | 1 |
| Joynt, GM | 1 |
| Nelson, KM | 1 |
| Patel, GP | 1 |
| Hammond, DA | 1 |
| García, JLB | 1 |
| Sáenz, MC | 1 |
| Gavilán, EDP | 1 |
| Chang, SY | 1 |
| Sun, RQ | 1 |
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| Howe, BD | 1 |
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| Bass, FE | 1 |
| Bin Kadiman, S | 1 |
| McArthur, CJ | 1 |
| Seppelt, IM | 2 |
| Takala, J | 1 |
| Wise, MP | 1 |
| Webb, SA | 1 |
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| Nguyen, HM | 1 |
| Park, H | 1 |
| Mehta, S | 2 |
| Epstein, SK | 1 |
| Youssef, F | 1 |
| Beltran, A | 1 |
| Flores, G | 1 |
| Sidhom, R | 1 |
| Sehgal, A | 1 |
| Leo, J | 1 |
| Smischney, NJ | 3 |
| Nicholson, WT | 1 |
| Brown, DR | 1 |
| Gallo De Moraes, A | 3 |
| Hoskote, SS | 3 |
| Pickering, B | 1 |
| Oeckler, RA | 1 |
| Iyer, VN | 2 |
| Gajic, O | 1 |
| Schroeder, DR | 1 |
| Bauer, PR | 1 |
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| Iapichino, G | 1 |
| Xu, AY | 1 |
| Hong, GL | 1 |
| Zhao, GJ | 1 |
| Wu, B | 1 |
| Qiu, QM | 1 |
| Lu, ZQ | 1 |
| Schroeppel, TJ | 1 |
| Fabian, TC | 1 |
| Clement, LP | 1 |
| Magnotti, LJ | 1 |
| Sharpe, JP | 1 |
| Lee, M | 1 |
| Croce, MA | 1 |
| Bass, F | 1 |
| Howe, B | 1 |
| McArthur, C | 1 |
| Webb, S | 1 |
| Weisbrodt, L | 1 |
| Xia, ZQ | 1 |
| Chen, SQ | 1 |
| Yao, X | 1 |
| Xie, CB | 1 |
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| Liu, KX | 1 |
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| Guo, F | 1 |
| Teboul, JL | 1 |
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| Sharma, A | 1 |
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| Trikha, A | 2 |
| Rewari, V | 2 |
| Koenig, SJ | 1 |
| Lakticova, V | 1 |
| Narasimhan, M | 1 |
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| Magee, C | 1 |
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| Fraser, GL | 2 |
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| Glisic, EK | 1 |
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| Dotson, B | 1 |
| Tennenberg, SD | 1 |
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| Kress, JP | 5 |
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| Sweeney, M | 1 |
| Knibbe, CA | 4 |
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| Occhiochiuso, L | 1 |
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| Alling, C | 1 |
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| Malmros, C | 1 |
| Walder, B | 2 |
| Tramèr, MR | 2 |
| Sundaram, R | 1 |
| Dell, AE | 1 |
| Miner, JR | 1 |
| Martel, ML | 1 |
| Meyer, M | 1 |
| Reardon, R | 1 |
| Biros, MH | 1 |
| Martin, J | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Midazolam Used Alone or Sequential Use of Midazolam and Propofol/Dexmedetomidine for Long-Term Sedation in Critically Ill, Mechanically Ventilated Patients: a Prospective, Randomized Study[NCT02528513] | Phase 4 | 240 participants (Anticipated) | Interventional | 2015-12-31 | Enrolling by invitation | ||
| Non-sedation Versus Sedation With a Daily Wake-up Trial in Critically Ill Patients Receiving Mechanical Ventilation. The NONSEDA-trial. An Investigator-initiated, Randomised, Clinical, Parallel-group, Multinational, Superiority Trial[NCT01967680] | 700 participants (Actual) | Interventional | 2014-01-31 | Completed | |||
| A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05327296] | Phase 3 | 235 participants (Anticipated) | Interventional | 2022-06-30 | Recruiting | ||
| A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05312385] | Phase 3 | 235 participants (Anticipated) | Interventional | 2022-04-28 | Recruiting | ||
| Altering Sedation Paradigms to Improve Brain Injury and Survival in Severe Sepsis[NCT01739933] | Phase 3 | 438 participants (Actual) | Interventional | 2013-05-15 | Completed | ||
| Comparison of Propofol and Dexmedetomidine to Treat Hyperactive and Mixed ICU Delirium - the Basel ProDex Randomized Trial[NCT02807467] | Phase 4 | 37 participants (Actual) | Interventional | 2019-03-01 | Terminated (stopped due to insufficient recruitment over a long period) | ||
| Dexmedetomidine Cycling and Sleep in the Pediatric ICU[NCT05003102] | Phase 4 | 0 participants (Actual) | Interventional | 2023-02-20 | Withdrawn (stopped due to No enrollment, IRB closed) | ||
| The Effect of a Dexmedetomidine-focussed Sleep Protocol* on Delirium Incidence and Healthcare Costs in Critically Ill Patients: A Prospective Randomized, Double-blind, Pilot Study.[NCT01791296] | Phase 4 | 100 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| Impacts of Dexmedetomidine as an Adjuvant for Femoral Nerve Block on Functional Recovery in Aged Patients After Total Knee Arthroplasty: a Randomized, Double-blinded, Controlled Trial[NCT04642651] | Phase 4 | 170 participants (Actual) | Interventional | 2020-11-25 | Completed | ||
| Effect of Low-dose Dexmedetomidine on Postoperative Delirium in Patients After Cardiac Surgery: A Multicenter, Double-blinded, Randomized Controlled Trial[NCT03624595] | 502 participants (Anticipated) | Interventional | 2019-04-16 | Active, not recruiting | |||
| Early Goal-Directed Sedation Compared With Standard Care in Mechanically Ventilated Critically Ill Patients: a Prospective Multicentre Randomised Controlled Trial[NCT01728558] | Phase 3 | 4,000 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| Efficacy and Safety of Remimazolam for Sedation in ICU Patients Undergoing Mechanical Ventilation: a Single Center, Randomized, Controlled, Non-inferiority Trial[NCT04815265] | Phase 4 | 488 participants (Anticipated) | Interventional | 2021-04-01 | Not yet recruiting | ||
| Sedation, ANalgesia and Delirium MANagement: a Study of Medical, Surgical, Trauma, and Neuro-intensive Care Patients and a COVID-19 Sub-study.[NCT05027217] | 3,421 participants (Actual) | Observational | 2022-01-01 | Completed | |||
| "Ketamine / Propofol Admixture Ketofol at Induction in the Critically Ill Against Etomidate: KEEP PACE Trial"[NCT02105415] | Phase 2/Phase 3 | 160 participants (Actual) | Interventional | 2014-04-30 | Completed | ||
| Multicentric, Single Blind, Randomized Controlled Trial on Enteral Sedation Versus Intravenous Sedation in Critically Ill High-risk ICU Patients[NCT01360346] | Phase 3 | 300 participants (Anticipated) | Interventional | 2012-01-31 | Recruiting | ||
| Impact of Night-time Dexmedetomidine-esketamine Infusion on Sleep Quality of Patients With Mechanical Ventilation in ICU: a Randomized Controlled Trial[NCT05718024] | Phase 4 | 174 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | ||
| Low-dose Dexmedetomidine for Delirium Prevention in Mechanically Ventilated Patients in Intensive Care Unit: a Multicenter, Randomised, Double-blinded, Placebo-controlled Trial[NCT03172897] | Phase 4 | 260 participants (Anticipated) | Interventional | 2017-08-20 | Suspended (stopped due to The trial was stopped because of difficulty in recruiting patients (another trial had similar inclusion/exclusion criteria). No patients was recruited in this trial.) | ||
| Dexmedetomidine-esketamine Combined With Oxycodone for Ultrasound-guided Percutaneous Radiofrequency Ablation in Patients With Liver Cancer: a Randomized Controlled Study[NCT06003218] | 88 participants (Anticipated) | Interventional | 2023-10-16 | Recruiting | |||
| Impact of Low-Dose Dexmedetomidine on Sleep Quality in Mechanical Ventilation Patients After Surgery in Intensive Care Unit: a Pilot Randomized, Double-Blind, Placebo-Controlled Trial[NCT03335527] | Phase 4 | 80 participants (Actual) | Interventional | 2017-11-17 | Completed | ||
| Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Unit[NCT03194360] | 141 participants (Actual) | Observational | 2015-12-01 | Completed | |||
| The Use of Transcranial Focused Ultrasound for the Treatment of Neurodegenerative Dementias[NCT04250376] | 100 participants (Anticipated) | Interventional | 2017-11-27 | Enrolling by invitation | |||
| Lymphatic System Health in Alzheimer's Disease[NCT04205539] | Phase 1 | 0 participants (Actual) | Interventional | 2021-12-10 | Withdrawn (stopped due to Pending COVID-19 pandemic) | ||
| Ketofol vs Dexmedetomidine for Preventing Post-operative Delirium in Elderly Patients Undergoing Intestinal Obstruction Surgeries. A Randomized Controlled Study[NCT04816162] | Phase 4 | 120 participants (Actual) | Interventional | 2021-03-25 | Completed | ||
| Clinical Study of the Safety and Efficacy of Analgesia-first Minimal Sedation as an Early Antihypertensive Treatment for Spontaneous Intracerebral Hemorrhage[NCT03207100] | 338 participants (Actual) | Interventional | 2017-12-06 | Completed | |||
| Evaluation of Pupillary Distension Reflexes, as a Tool for the Monitoring of Analgesia for Patients in Intensive Care.[NCT02843893] | 51 participants (Actual) | Interventional | 2012-04-30 | Completed | |||
| Daily Interruption of Sedative Infusions in Mechanically Ventilated Children: A Randomized Pilot Study[NCT02426320] | 30 participants (Anticipated) | Interventional | 2015-04-30 | Recruiting | |||
| Substudy of Non-Seda Trial (NCT01967680): Non-sedation Versus Sedation With a Daily Wake-up Trial in Critically Ill Patients Receiving Mechanical Ventilation - Effects on Physical Function. An Investigator-initiated, Randomised, Clinical, Parallel-group, [NCT02034942] | 205 participants (Actual) | Interventional | 2014-01-31 | Completed | |||
| Advantages and Disadvantages of Long Term Sedation in ICU Patients[NCT00466492] | 140 participants (Actual) | Interventional | 2007-04-30 | Completed | |||
| Analgesia-First Sedation in Trauma Patients[NCT05751863] | 170 participants (Anticipated) | Interventional | 2023-04-01 | Recruiting | |||
| Awakening-Breathing Coordination, Delirium Monitoring/Management & Early Mobility (ABCDE) Protocol[NCT01413009] | 200 participants (Actual) | Observational | 2010-12-29 | Completed | |||
| Prevention of Oversedation in Intensive Care Patients Under Mechanical Ventilation : the AWARE Multicentric Randomized Trial[NCT01617265] | 1,180 participants (Actual) | Interventional | 2012-06-30 | Completed | |||
| Impact of Low-dose Dexmedetomidine on Outcomes of Elderly Admitted to ICU After Noncardiac Surgery: a Randomized Controlled Trial[NCT04204798] | 1,410 participants (Anticipated) | Interventional | 2020-08-28 | Recruiting | |||
| Southern Medical University Clinical Research Project Initiative：Efficacy and Safety of a Multicomponent Physical Therapy Program in Mechanically Ventilated Patient With Sepsis[NCT03406494] | 800 participants (Anticipated) | Interventional | 2018-03-31 | Not yet recruiting | |||
| AnaConDa-therapy in COVID-19 Patients[NCT05586126] | 42 participants (Actual) | Observational | 2020-10-01 | Terminated (stopped due to Concerns about possible association between drug and increased ICU mortality) | |||
| Performance Assessment of the PMD-200 in Subjects Requiring Surgery Under General Anesthesia[NCT03467230] | 61 participants (Actual) | Observational | 2018-03-15 | Completed | |||
| Postoperative Sedation After Cardiac Surgery: Pilot Study[NCT02488486] | 19 participants (Actual) | Interventional | 2015-05-31 | Terminated (stopped due to Intermediate analysis) | |||
| Postoperative Sedation After Cardiac Surgery : Comparison Between Manual Administration and Automated Sedation[NCT03517735] | 7 participants (Actual) | Interventional | 2018-12-17 | Terminated (stopped due to Modification of the device) | |||
| The Pharmacokinetics of Fentanyl in Intensive Care Patients[NCT02587273] | Phase 4 | 150 participants (Anticipated) | Interventional | 2015-10-31 | Recruiting | ||
| Same-patient Reproducibility of Intraoperative M-Entropy Measurements[NCT00599066] | 24 participants (Actual) | Observational | 2007-09-30 | Completed | |||
| The Preventative Role of Exogenous Melatonin Administration in Patients With Advanced Cancer Who Are at Risk of Delirium: a Feasibility Study Prior to a Larger Randomized Controlled Trial[NCT02200172] | Phase 2 | 60 participants (Actual) | Interventional | 2014-12-31 | Completed | ||
| Etomidate With Meperidine vs Midazolam With Meperidine for Sedation During Endodscopic Retrograde Cholangiopancreatogram (ERCP)[NCT02027311] | Phase 4 | 63 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| Music as a Potential Intervention to Improve Hemodynamic Tolerability of Repetitive Sub-Anesthetic IV Ketamine Infusions in Bipolar and Unipolar Depression: A Pilot Study[NCT04701866] | 32 participants (Actual) | Interventional | 2021-01-11 | Completed | |||
| A Randomized Controlled Trial of Music vs. No Music During Cesarean Delivery on Patient Satisfaction[NCT03412019] | 22 participants (Actual) | Interventional | 2018-02-21 | Completed | |||
| Epidemiology of Weaning From Invasive Mechanical Ventilation in COVID-19. Observational and Multicenter Study.[NCT05049200] | 326 participants (Actual) | Observational [Patient Registry] | 2020-04-01 | Completed | |||
| Cognitive Impairment in the ICU: Evaluation and Outcomes[NCT00097630] | 334 participants | Interventional | 2003-10-31 | Completed | |||
| Prospective Study on the Cost-Effectiveness of Adding Ketamine to Midazolam-Sufentanil Sedation Regimen in Mechanically Ventilated Patients[NCT00122759] | 100 participants (Anticipated) | Interventional | 2005-12-31 | Recruiting | |||
| A Randomized Control Trial Using the BIS Monitor to Avoid Over Sedation and Prolonged Neuropsychological Deficits in Mechanically Ventilated ICU Patients[NCT00469482] | 28 participants (Actual) | Interventional | 2007-06-30 | Completed | |||
| ECMO-Free Trial: A Multicenter Pilot Feasibility Study[NCT05486559] | 60 participants (Anticipated) | Interventional | 2022-09-07 | Recruiting | |||
| Dynamic Light Application to Prevent ICU Acquired Delirium[NCT01274819] | 1,000 participants (Actual) | Interventional | 2011-07-31 | Completed | |||
| The Efficacy of Nurse-driven, Protocol Guided Ventilator Weaning in a Medical-Surgical ICU[NCT00786617] | 202 participants (Actual) | Observational | 2007-12-31 | Completed | |||
| Pilot Study for Peripheral Neuromuscular Electrical Stimulation of the Quadriceps Muscle: Healthy or Deprived of Central Nervous System Control[NCT05888714] | 15 participants (Anticipated) | Interventional | 2023-06-01 | Not yet recruiting | |||
| A Randomized, Double-blind, Controlled Trial of Cycling Continuous Sedative Infusions in Critically Ill Pediatric Patients Requiring Mechanical Ventilation[NCT01333059] | 25 participants (Actual) | Interventional | 2010-09-30 | Terminated (stopped due to Unable to adequately enroll over a reasonable enrollment period.) | |||
| Monitoring of Breathing Effort Through Pressure Time Product Measurement Using Airway Occlusion Pressure[NCT06040138] | 50 participants (Anticipated) | Observational | 2023-10-01 | Not yet recruiting | |||
| Effects of Sedatives on Sublingual Microcirculation of Patients With Septic Shock[NCT01618396] | 16 participants (Actual) | Interventional | 2011-03-31 | Completed | |||
| Sedation Administration Timing: Intermittent Dosing Reduces Time to Extubation (SATIRE Trial): A Prospective, Randomized Cohort Study[NCT03181620] | 200 participants (Anticipated) | Interventional | 2016-09-08 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The Telephone Interview for Cognitive Status is a standardized test of cognitive functioning that monitors changes in cognitive functioning over time. The TICS-T consists 11 items including wordlist memory, orientation, attention, repetition, conceptual knowledge and nonverbal praxis. Age-adjusted total scores on the TICS-T range from 0 to 100 with a mean of 50+/-10; lower scores indicate worse cognition, and a score of 35 or less indicates cognitive impairment. (NCT01739933)
Timeframe: 6 months after randomization
| Intervention | score on a scale (Median) |
|---|---|
| Dexmedetomidine | 39 |
| Propofol | 38 |
That sedation of mechanically ventilated severely septic patients with an alpha2 agonist (dexmedetomidine) rather than a GABAergic agent (propofol) will improve 90-day survival of ICU patients. (NCT01739933)
Timeframe: 1 through 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Dexmedetomidine | 81 |
| Propofol | 82 |
The analysis of DCFDs will be conducted using Intention-to-Treat (ITT) population, defined as all patients who were randomized and received study drug. We chose a 14 day evaluation period for delirium, because it represents the best balance of gaining valuable clinical information, while maximizing resource utilization, given the average study drug infusion to be 7 days and maximum duration to be 14 days. Thus our follow-up period will cover 7 additional days of delirium monitoring after the study drug is stopped in the majority of our patients. (NCT01739933)
Timeframe: 14 days
| Intervention | days (Median) |
|---|---|
| Dexmedetomidine | 8 |
| Propofol | 7.5 |
Ventilator-free days (VFDs), i.e., days alive and free of mechanical ventilation (MV) at 28 days. This endpoint has been used by the National Heart, Lung, and Blood Institute (NHLBI) ARDSNet in numerous critical care trials examining ICU populations. (NCT01739933)
Timeframe: 28 Days
| Intervention | days (Median) |
|---|---|
| Dexmedetomidine | 20.9 |
| Propofol | 19.9 |
comparison of intensive care unit free days between the two groups (NCT02105415)
Timeframe: hospital discharge or day 28, whichever comes first
| Intervention | days (Median) |
|---|---|
| Etomidate | 16 |
| Ketamine / Propofol Admixture | 17 |
comparison of mechanical ventilation free days between the two groups (NCT02105415)
Timeframe: hospital discharge or day 28, whichever comes first
| Intervention | days (Median) |
|---|---|
| Etomidate | 22 |
| Ketamine / Propofol Admixture | 20 |
In-hospital/28 day mortality among patients in ketamine/propofol combination compared to in-hospital/28-day mortality in etomidate. (NCT02105415)
Timeframe: Hospital Discharge or Day 28, whichever comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Etomidate | 26 |
| Ketamine / Propofol Admixture | 25 |
Comparison of number of participants who were positive for delirium using CAM-ICU between groups (NCT02105415)
Timeframe: up to 24 hours post study drug administration
| Intervention | Participants (Count of Participants) |
|---|---|
| Etomidate | 7 |
| Ketamine / Propofol Admixture | 4 |
Incidence of adrenal insufficiency between ketamine/propofol admixture and etomidate. Adrenal insuffiency was evaluated with co-syntropin stimulation test. (NCT02105415)
Timeframe: up to 24 hours post study drug administration
| Intervention | Participants (Count of Participants) |
|---|---|
| Etomidate (3-5 Hours) | 13 |
| Ketamine/Propofol Admixture (3-5 Hours) | 5 |
| Etomidate (23-25 Hours) | 9 |
| Ketamine/Propofol Admixture (23-25 Hours) | 6 |
blood product transfusions [Red Blood Cells vs. non-Red Blood Cells] between the two groups (NCT02105415)
Timeframe: hospital discharge or day 28, whichever comes first
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Red blood cell | Non-red blood cell | Colloid | |
| Etomidate | 21 | 16 | 28 |
| Ketamine / Propofol Admixture | 13 | 8 | 26 |
Mean arterial pressure for the ketamine/propofol group at a 1:1 dose ratio compared to the etomidate group within the first 15 minutes post-administration in patients in need of urgent and/or emergent endotracheal intubation, as defined by any intubation within the intensive care unit excluding intubations for elective procedural events and codes. (NCT02105415)
Timeframe: baseline and every 5 minutes up to 15 minutes minutes post study drug administration
| Intervention | mm Hg (Mean) | |||
|---|---|---|---|---|
| Baseline | 5 minutes | 10 minutes | 15 minutes | |
| Etomidate | 82.8 | 81.7 | 81.9 | 79.1 |
| Ketamine / Propofol Admixture | 80.9 | 77.6 | 75.3 | 75.5 |
The use of vasoactive medications to restore the blood pressure post-administration in the ketamine/propofol combination as compared to the etomidate group. (NCT02105415)
Timeframe: up to 24 hours post study drug administration
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Pre-treament | New-onset pressors (within 3 minutes) | Delayed-onset pressors (within 24 hours) | |
| Etomidate | 1 | 12 | 57 |
| Ketamine / Propofol Admixture | 5 | 18 | 64 |
Hypoxia defined as peripheral blood oxygen saturation measured by pulse oxymeter < 90% (NCT02027311)
Timeframe: Every 5min in Preoperative, intraoperative phase and 15 min in Recovery phase
| Intervention | Hypoxia events (Number) |
|---|---|
| Midazolam | 19 |
| Etomidate | 27 |
The frequency of intervention which was defined as any restraint of the patient's head, arms, or legs if they became agitated, or if patient movement was not controlled with verbal instruction from the endoscopist during the whole intraoperative phases. (NCT02027311)
Timeframe: Throughout the whole ERCP procedure
| Intervention | Number of intervention (Mean) |
|---|---|
| Etomidate | 1.9 |
| Midazolam | 7.5 |
This is the post-procedure mean arterial pressure of the patients. (NCT03412019)
Timeframe: post procedure
| Intervention | mmHg (Mean) |
|---|---|
| Control Group | 82.2 |
| Intervention Group | 80.4 |
Change in anxiety before and after surgery using a numeric rating scale from 0 (no anxiety at all) to 10 (greatest anxiety) (NCT03412019)
Timeframe: Perioperatively
| Intervention | NRS scale (0-10) (Mean) |
|---|---|
| Control Group | 2.5 |
| Intervention Group | 2.7 |
"This outcome will be measured using Morgan's Maternal Satisfaction Scale for Cesarean Section (MSSCS).~It is a 22-item questionnaire, each item have a Likert scale from 1-7 (1 =strongly disagree, 7=strongly agree), yielding a composite (total) score ranging 22-154, representing lowest to highest satisfaction. The questionnaire will be given to participants on post-operative day one during the hours of 8am-1pm." (NCT03412019)
Timeframe: 1 Day
| Intervention | units on a scale (Mean) |
|---|---|
| Control Group | 120 |
| Intervention Group | 116 |
Participants will be followed for an expected average of 4 days. The Data Safety Monitoring Group will review the data every 6 months. (NCT01333059)
Timeframe: From date of randomization until the date of discharge from PICU, assessed up to 1 month
| Intervention | days (Mean) |
|---|---|
| Experimental Group | 10.14 |
| Control Group | 5.82 |
Participants will be followed for an expected average of 7 days in PICU and 10 days of hospitalization. This secondary endpoint is to be evaluated every six months. (NCT01333059)
Timeframe: From date of hospital admission to date of hospital discharge, assessed up to 6 weeks
| Intervention | days (Mean) |
|---|---|
| Experimental Group | 25.21 |
| Control Group | 20.82 |
Participants will be followed for an expected average of 7 days. This secondary endpoint is to be evaluated every six months. (NCT01333059)
Timeframe: From date of randomization until the date of discharge from PICU, assessed up to 1 month
| Intervention | days (Mean) |
|---|---|
| Experimental Group | 13.93 |
| Control Group | 9.82 |
24 reviews available for propofol and Critical Illness
| Article | Year |
|---|---|
Outcomes of dexmedetomidine versus propofol sedation in critically ill adults requiring mechanical ventilation: a systematic review and meta-analysis of randomised controlled trials.
Topics: Adult; Bradycardia; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; In | 2022 |
Ketamine sedation in mechanically ventilated patients: A systematic review and meta-analysis.
Topics: Anesthesia; Critical Illness; Fentanyl; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Observ | 2020 |
Sedation for critically ill patients with COVID-19: Which specificities? One size does not fit all.
Topics: Analgesics, Opioid; Betacoronavirus; Coronavirus Infections; COVID-19; Critical Illness; Deep Sedati | 2020 |
Altered Pharmacokinetics in Prolonged Infusions of Sedatives and Analgesics Among Adult Critically Ill Patients: A Systematic Review.
Topics: Adult; Analgesics; Critical Illness; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Inf | 2018 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2013 |
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Bradycardia; Clonidine; Conscious Sedation; Critical Il | 2015 |
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Bradycardia; Clonidine; Conscious Sedation; Critical Il | 2015 |
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Bradycardia; Clonidine; Conscious Sedation; Critical Il | 2015 |
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Bradycardia; Clonidine; Conscious Sedation; Critical Il | 2015 |
Optimizing sedation in patients with acute brain injury.
Topics: Analgesia; Brain Injuries; Critical Care; Critical Illness; Deep Sedation; Humans; Hypnotics and Sed | 2016 |
The use of propofol for medium and long-term sedation in critically ill adult patients: a meta-analysis.
Topics: Adult; Chi-Square Distribution; Critical Illness; Humans; Hypnotics and Sedatives; Intensive Care Un | 2008 |
Prolonged propofol use in a critically ill pregnant patient.
Topics: Abortion, Induced; Adult; Anesthetics, Intravenous; Animals; Child; Critical Illness; Female; Humans | 2010 |
Propofol infusion syndrome in critically ill patients.
Topics: Adult; Anesthetics, Intravenous; Cardiac Output, Low; Child; Critical Care; Critical Illness; Humans | 2002 |
Sedation in the intensive care unit.
Topics: Benzodiazepines; Butyrophenones; Conscious Sedation; Critical Care; Critical Illness; Humans; Narcot | 2002 |
The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome.
Topics: Adult; Animals; Catecholamines; Central Nervous System; Critical Illness; Drug Interactions; Drug Th | 2003 |
Management of agitation in the intensive care unit.
Topics: Benzodiazepines; Clinical Protocols; Critical Care; Critical Illness; Delirium; Humans; Hypnotics an | 2003 |
Analgesia and sedation in critically ill patients.
Topics: Algorithms; Analgesics; Analgesics, Opioid; Critical Illness; Humans; Hypnotics and Sedatives; Midaz | 2004 |
Economic evaluation of propofol and lorazepam for critically ill patients undergoing mechanical ventilation.
Topics: Cost-Benefit Analysis; Critical Illness; Decision Trees; Humans; Hypnotics and Sedatives; Lorazepam; | 2008 |
[Delusion in the critical patient].
Topics: Antipsychotic Agents; Benzodiazepines; Critical Illness; Delusions; Diagnostic and Statistical Manua | 2008 |
Pharmacology of intravenous sedatives and opioids in critically ill patients.
Topics: Analgesics, Opioid; Antipsychotic Agents; Barbiturates; Benzodiazepines; Cardiovascular System; Crit | 1994 |
Propofol for the long-term sedation of a critically ill patient.
Topics: Adult; Conscious Sedation; Critical Care; Critical Illness; Humans; Hypnotics and Sedatives; Infusio | 1998 |
Propofol toxicity in critically ill pediatric patients: show us the proof.
Topics: Acidosis, Lactic; Anesthetics, Intravenous; Bradycardia; Child; Child, Preschool; Conscious Sedation | 1998 |
A lack of evidence of superiority of propofol versus midazolam for sedation in mechanically ventilated critically ill patients: a qualitative and quantitative systematic review.
Topics: Critical Care; Critical Illness; Humans; Hypnotics and Sedatives; Midazolam; Propofol; Randomized Co | 2001 |
Pain management in the critically ill child.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Child; Child, Preschool; Critical Illness; Fentan | 2001 |
Sedation in critically ill patients: a review.
Topics: Adult; Age Factors; Aged; Analgesics; Critical Illness; Electroencephalography; Humans; Hypnotics an | 2001 |
Use of propofol and other nonbenzodiazepine sedatives in the intensive care unit.
Topics: Critical Illness; Dexmedetomidine; Etomidate; Haloperidol; Humans; Hypnotics and Sedatives; Intensiv | 2001 |
[Pharmacology in critical illness].
Topics: Adrenergic Agonists; Anesthetics, Intravenous; Animals; Calcium Channel Blockers; Cardiopulmonary Re | 2001 |
56 trials available for propofol and Critical Illness
| Article | Year |
|---|---|
Dexmedetomidine dosage in critically ill patients undergoing intraoperative wake-up test: A randomized controlled trial.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Propofol; Remifentanil; Scoliosis | 2022 |
Sequential use of midazolam and dexmedetomidine for long-term sedation may reduce weaning time in selected critically ill, mechanically ventilated patients: a randomized controlled study.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Propofol; Resp | 2022 |
Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; | 2022 |
Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; | 2022 |
Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; | 2022 |
Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; | 2022 |
Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; | 2022 |
Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; | 2022 |
Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; | 2022 |
Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; | 2022 |
Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; | 2022 |
Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients - A randomized controlled trial.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Pro | 2023 |
Letter to the Editor: "Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients - A randomized controlled trial".
Topics: Anesthesia; Anesthetics, Inhalation; Conscious Sedation; Critical Illness; Humans; Hypnotics and Sed | 2023 |
Author's response: Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients - A randomized controlled trial.
Topics: Conscious Sedation; Critical Illness; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofo | 2023 |
Remimazolam besylate versus propofol for deep sedation in critically ill patients: a randomized pilot study.
Topics: Critical Illness; Deep Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Pilot Projects; P | 2023 |
The effectiveness of systematic pain assessment on critically ill patient outcomes: A randomised controlled trial.
Topics: Critical Illness; Humans; Pain Measurement; Propofol | 2020 |
Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients.
Topics: Aged; Aged, 80 and over; Coma; Conscious Sedation; Critical Illness; Delirium; Female; Humans; Hypno | 2020 |
Burst Suppression: Causes and Effects on Mortality in Critical Illness.
Topics: Adult; Critical Care; Critical Illness; Humans; Intensive Care Units; Propofol; Respiration, Artific | 2020 |
Dexmedetomidine versus propofol for prolonged sedation in critically ill trauma and surgical patients.
Topics: Adolescent; Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Car | 2021 |
Dose and cardiopulmonary effects of propofol alone or with midazolam for induction of anesthesia in critically ill dogs.
Topics: Anesthesia; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Critical Illness; Dog Diseases | 2020 |
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.
Topics: Adult; Cognition; Conscious Sedation; Critical Illness; Dexmedetomidine; Double-Blind Method; Humans | 2021 |
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.
Topics: Adult; Cognition; Conscious Sedation; Critical Illness; Dexmedetomidine; Double-Blind Method; Humans | 2021 |
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.
Topics: Adult; Cognition; Conscious Sedation; Critical Illness; Dexmedetomidine; Double-Blind Method; Humans | 2021 |
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.
Topics: Adult; Cognition; Conscious Sedation; Critical Illness; Dexmedetomidine; Double-Blind Method; Humans | 2021 |
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.
Topics: Adult; Cognition; Conscious Sedation; Critical Illness; Dexmedetomidine; Double-Blind Method; Humans | 2021 |
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.
Topics: Adult; Cognition; Conscious Sedation; Critical Illness; Dexmedetomidine; Double-Blind Method; Humans | 2021 |
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.
Topics: Adult; Cognition; Conscious Sedation; Critical Illness; Dexmedetomidine; Double-Blind Method; Humans | 2021 |
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.
Topics: Adult; Cognition; Conscious Sedation; Critical Illness; Dexmedetomidine; Double-Blind Method; Humans | 2021 |
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.
Topics: Adult; Cognition; Conscious Sedation; Critical Illness; Dexmedetomidine; Double-Blind Method; Humans | 2021 |
Comparison of propofol and dexmedetomidine infused overnight to treat hyperactive and mixed ICU delirium: a protocol for the Basel ProDex clinical trial.
Topics: Critical Illness; Delirium; Dexmedetomidine; Electroencephalography; Humans; Hypnotics and Sedatives | 2017 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critica | 2018 |
The use of remifentanil in critically ill patients undergoing percutaneous dilatational tracheostomy: A prospective randomized-controlled trial.
Topics: Adult; Critical Illness; Female; Hemodynamics; Humans; Male; Pain; Propofol; Prospective Studies; Re | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combi | 2019 |
Analgesia-first sedation in critically ill adults: A U.S. pilot, randomized controlled trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Anesthesia; California; Clinical Protocols; Critical Illness; D | 2019 |
Ketamine/propofol admixture vs etomidate for intubation in the critically ill: KEEP PACE Randomized clinical trial.
Topics: Adult; Anesthetics, Intravenous; Critical Illness; Dose-Response Relationship, Drug; Drug Monitoring | 2019 |
Enteral vs. intravenous ICU sedation management: study protocol for a randomized controlled trial.
Topics: Administration, Oral; Anesthetics, Intravenous; Clinical Protocols; Computer-Assisted Instruction; C | 2013 |
Early goal-directed sedation versus standard sedation in mechanically ventilated critically ill patients: a pilot study*.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Airway Extubation; Algorithms; APACHE; Benzodiazepines; | 2013 |
The effects of propofol and dexmedetomidine infusion on fluid responsiveness in critically ill patients.
Topics: Aged; Aged, 80 and over; Critical Illness; Dexmedetomidine; Female; Fluid Therapy; Hemodynamics; Hum | 2013 |
Entropy correlates with Richmond Agitation Sedation Scale in mechanically ventilated critically ill patients.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Conscious Sedation; Consciousness; Consciousness | 2014 |
Midazolam and propofol used alone or sequentially for long-term sedation in critically ill, mechanically ventilated patients: a prospective, randomized study.
Topics: Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthetics, Intravenous; Critical Illness; Dru | 2014 |
Randomized, placebo-controlled trial of acetaminophen for the reduction of oxidative injury in severe sepsis: the Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cell-Free System; Creatinine; Critical Illness; Doub | 2015 |
[The effect of mild sedation on the prognosis and inflammatory markers in critical patients with mechanical ventilation].
Topics: Biomarkers; Critical Illness; Humans; Hypnotics and Sedatives; Inflammation; Intensive Care Units; I | 2014 |
Ketamine/propofol admixture (ketofol) at induction in the critically ill against etomidate (KEEP PACE trial): study protocol for a randomized controlled trial.
Topics: Adrenal Glands; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Clinical | 2015 |
Ketamine/propofol admixture (ketofol) at induction in the critically ill against etomidate (KEEP PACE trial): study protocol for a randomized controlled trial.
Topics: Adrenal Glands; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Clinical | 2015 |
Ketamine/propofol admixture (ketofol) at induction in the critically ill against etomidate (KEEP PACE trial): study protocol for a randomized controlled trial.
Topics: Adrenal Glands; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Clinical | 2015 |
Ketamine/propofol admixture (ketofol) at induction in the critically ill against etomidate (KEEP PACE trial): study protocol for a randomized controlled trial.
Topics: Adrenal Glands; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Clinical | 2015 |
[Effects of combination of midazolam and propofol on anterograde amnesia in critical patients].
Topics: Adolescent; Adult; Amnesia; Critical Illness; Drug Therapy, Combination; Female; Humans; Hypnotics a | 2008 |
A randomized evaluation of bispectral index-augmented sedation assessment in neurological patients.
Topics: Adult; Aged; Consciousness; Critical Care; Critical Illness; Electroencephalography; Female; Humans; | 2009 |
Daily interruption of sedative infusions in an adult medical-surgical intensive care unit: randomized controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Critical Care; Critical Illness; F | 2009 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial.
Topics: Aged; Clinical Protocols; Critical Care; Critical Illness; Denmark; Drug Administration Schedule; Fe | 2010 |
Association of preservative-free propofol use and outcome in critically ill patients.
Topics: Cohort Studies; Critical Illness; Cross Infection; Dose-Response Relationship, Drug; Female; Hospita | 2011 |
Effects of propofol on sleep quality in mechanically ventilated critically ill patients: a physiological study.
Topics: Adult; Aged; Critical Care; Critical Illness; Cross-Over Studies; Female; Humans; Hypnotics and Seda | 2012 |
A reorientation strategy for reducing delirium in the critically ill. Results of an interventional study.
Topics: Acoustic Stimulation; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Critical Care; | 2012 |
Efficiency and safety of inhalative sedation with sevoflurane in comparison to an intravenous sedation concept with propofol in intensive care patients: study protocol for a randomized controlled trial.
Topics: Administration, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Cost-Benefit Analysis | 2012 |
Automated sedation outperforms manual administration of propofol and remifentanil in critically ill patients with deep sedation: a randomized phase II trial.
Topics: Adult; Aged; Algorithms; Anesthetics, Intravenous; Automation; Critical Illness; Deep Sedation; Fema | 2013 |
Automated sedation outperforms manual administration of propofol and remifentanil in critically ill patients with deep sedation: a randomized phase II trial.
Topics: Adult; Aged; Algorithms; Anesthetics, Intravenous; Automation; Critical Illness; Deep Sedation; Fema | 2013 |
Automated sedation outperforms manual administration of propofol and remifentanil in critically ill patients with deep sedation: a randomized phase II trial.
Topics: Adult; Aged; Algorithms; Anesthetics, Intravenous; Automation; Critical Illness; Deep Sedation; Fema | 2013 |
Automated sedation outperforms manual administration of propofol and remifentanil in critically ill patients with deep sedation: a randomized phase II trial.
Topics: Adult; Aged; Algorithms; Anesthetics, Intravenous; Automation; Critical Illness; Deep Sedation; Fema | 2013 |
Automated sedation outperforms manual administration of propofol and remifentanil in critically ill patients with deep sedation: a randomized phase II trial.
Topics: Adult; Aged; Algorithms; Anesthetics, Intravenous; Automation; Critical Illness; Deep Sedation; Fema | 2013 |
Automated sedation outperforms manual administration of propofol and remifentanil in critically ill patients with deep sedation: a randomized phase II trial.
Topics: Adult; Aged; Algorithms; Anesthetics, Intravenous; Automation; Critical Illness; Deep Sedation; Fema | 2013 |
Automated sedation outperforms manual administration of propofol and remifentanil in critically ill patients with deep sedation: a randomized phase II trial.
Topics: Adult; Aged; Algorithms; Anesthetics, Intravenous; Automation; Critical Illness; Deep Sedation; Fema | 2013 |
Automated sedation outperforms manual administration of propofol and remifentanil in critically ill patients with deep sedation: a randomized phase II trial.
Topics: Adult; Aged; Algorithms; Anesthetics, Intravenous; Automation; Critical Illness; Deep Sedation; Fema | 2013 |
Automated sedation outperforms manual administration of propofol and remifentanil in critically ill patients with deep sedation: a randomized phase II trial.
Topics: Adult; Aged; Algorithms; Anesthetics, Intravenous; Automation; Critical Illness; Deep Sedation; Fema | 2013 |
Population pharmacokinetic and pharmacodynamic modeling of propofol for long-term sedation in critically ill patients: a comparison between propofol 6% and propofol 1%.
Topics: Adult; Aged; Aged, 80 and over; APACHE; Body Temperature; Chemistry, Pharmaceutical; Critical Illnes | 2002 |
Long-term sedation with propofol 60 mg ml(-1) vs. propofol 10 mg(-1) ml in critically ill, mechanically ventilated patients.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Conscious Sedation; Critical Illness; Drug | 2004 |
Abolished circadian rhythm of melatonin secretion in sedated and artificially ventilated intensive care patients.
Topics: Aged; Aged, 80 and over; Circadian Rhythm; Critical Care; Critical Illness; Drug Therapy, Combinatio | 2004 |
Effects of propofol vs methohexital on neutrophil function and immune status in critically ill patients.
Topics: Adult; Aged; Anesthetics, Intravenous; Antigens, CD; Biomarkers; Brain Injuries; Conscious Sedation; | 2006 |
Glycine and ammonia plasma concentrations during sedation with remifentanil in critically ill patients.
Topics: Adult; Ammonia; Creatinine; Critical Illness; Female; Glycine; Humans; Hypnotics and Sedatives; Infu | 2007 |
Effect of a nurse-implemented sedation protocol on the incidence of ventilator-associated pneumonia.
Topics: Adult; Aged; Conscious Sedation; Critical Illness; Female; Humans; Male; Midazolam; Middle Aged; Pne | 2007 |
Effect of a nurse-implemented sedation protocol on the incidence of ventilator-associated pneumonia.
Topics: Adult; Aged; Conscious Sedation; Critical Illness; Female; Humans; Male; Midazolam; Middle Aged; Pne | 2007 |
Effect of a nurse-implemented sedation protocol on the incidence of ventilator-associated pneumonia.
Topics: Adult; Aged; Conscious Sedation; Critical Illness; Female; Humans; Male; Midazolam; Middle Aged; Pne | 2007 |
Effect of a nurse-implemented sedation protocol on the incidence of ventilator-associated pneumonia.
Topics: Adult; Aged; Conscious Sedation; Critical Illness; Female; Humans; Male; Midazolam; Middle Aged; Pne | 2007 |
Pilot study on the influence of liver blood flow and cardiac output on the clearance of propofol in critically ill patients.
Topics: Aged; Anesthetics; Cardiac Output; Critical Illness; Female; Humans; Liver; Male; Middle Aged; Nonli | 2008 |
Overture for growth hormone: requiem for interleukin-6?
Topics: Aged; Blood Pressure; Critical Illness; Dehydroepiandrosterone; Epinephrine; Female; Human Growth Ho | 2007 |
Overture for growth hormone: requiem for interleukin-6?
Topics: Aged; Blood Pressure; Critical Illness; Dehydroepiandrosterone; Epinephrine; Female; Human Growth Ho | 2007 |
Overture for growth hormone: requiem for interleukin-6?
Topics: Aged; Blood Pressure; Critical Illness; Dehydroepiandrosterone; Epinephrine; Female; Human Growth Ho | 2007 |
Overture for growth hormone: requiem for interleukin-6?
Topics: Aged; Blood Pressure; Critical Illness; Dehydroepiandrosterone; Epinephrine; Female; Human Growth Ho | 2007 |
Propofol emulsion reduces proliferative responses of lymphocytes from intensive care patients.
Topics: Adolescent; Adult; Aged; B-Lymphocytes; Chemistry, Pharmaceutical; Concanavalin A; Critical Illness; | 1993 |
Propofol vs midazolam in short-, medium-, and long-term sedation of critically ill patients. A cost-benefit analysis.
Topics: Aged; Aged, 80 and over; Conscious Sedation; Cost-Benefit Analysis; Critical Illness; Female; Humans | 1993 |
Sedation of critically ill patients during mechanical ventilation. A comparison of propofol and midazolam.
Topics: APACHE; Conscious Sedation; Critical Illness; Female; Humans; Hypnotics and Sedatives; Infusions, In | 1996 |
Comparative study of propofol versus midazolam in the sedation of critically ill patients: results of a prospective, randomized, multicenter trial.
Topics: Adolescent; Adult; Aged; Conscious Sedation; Critical Care; Critical Illness; Female; Hemodynamics; | 1996 |
Prolonged sedation of critically ill patients with midazolam or propofol: impact on weaning and costs.
Topics: Adult; Aged; Critical Care; Critical Illness; Drug Costs; Female; Hospitals, Community; Humans; Hype | 1997 |
Use of 2% propofol to produce diurnal sedation in critically ill patients.
Topics: Adult; Aged; APACHE; Arousal; Chronotherapy; Critical Illness; Female; Humans; Hypnotics and Sedativ | 1997 |
Propofol 2% in critically ill patients: effect on lipids.
Topics: Acute-Phase Reaction; Adult; Aged; APACHE; C-Reactive Protein; Critical Care; Critical Illness; Fema | 1997 |
Midazolam versus propofol for long-term sedation in the ICU: a randomized prospective comparison.
Topics: Adult; Critical Illness; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazo | 1997 |
Continuous infusions of lorazepam, midazolam, and propofol for sedation of the critically ill surgery trauma patient: a prospective, randomized comparison.
Topics: Adolescent; Adult; Aged; Conscious Sedation; Costs and Cost Analysis; Critical Illness; Drug Costs; | 1999 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Drug Administration Schedule; Female; Humans; Hyp | 2000 |
The immunomodulatory effects of prolonged intravenous infusion of propofol versus midazolam in critically ill surgical patients.
Topics: Adult; Analysis of Variance; APACHE; Biomarkers; Critical Illness; Enzyme-Linked Immunosorbent Assay | 2001 |
Trace element homeostasis during continuous sedation with propofol containing EDTA versus other sedatives in critically ill patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; APACHE; Calcium; Chelating Age | 2000 |
96 other studies available for propofol and Critical Illness
| Article | Year |
|---|---|
Effect of Sedatives on In-hospital and Long-term Mortality of Critically Ill Patients Requiring Extended Mechanical Ventilation for ≥ 48 Hours.
Topics: Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critical Illness; Dexmedetomidine; Female; | 2021 |
Hypertriglyceridemia in Critically Ill Patients With SARS-CoV-2 Infection.
Topics: Adult; COVID-19; Critical Illness; Female; Humans; Hypertriglyceridemia; Intensive Care Units; Lipas | 2022 |
Comparing the impact on the prognosis of acute myocardial infarction critical patients of using midazolam, propofol, and dexmedetomidine for sedation.
Topics: Aged; Aged, 80 and over; Coronary Care Units; Critical Illness; Databases, Factual; Dexmedetomidine; | 2021 |
Specific nutrition and metabolic characteristics of critically ill patients with persistent COVID-19.
Topics: Aged; COVID-19; Critical Illness; Energy Intake; Female; Humans; Intensive Care Units; Male; Middle | 2022 |
An analysis of nonnutritive calories from propofol, dextrose, and citrate among patients who are critically ill that are receiving continuous renal replacement therapy.
Topics: Citric Acid; Continuous Renal Replacement Therapy; Critical Illness; Glucose; Humans; Intensive Care | 2022 |
Long-term ketamine infusion-induced cholestatic liver injury in COVID-19-associated acute respiratory distress syndrome.
Topics: Bilirubin; COVID-19; Critical Illness; Humans; Hypnotics and Sedatives; Ketamine; Liver; Propofol; R | 2022 |
The incidence of propofol infusion syndrome in critically-ill patients.
Topics: Adult; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Propofol; Propofol Infusion Syn | 2022 |
Investigation of Behavioural Pain Scale, Critical Care Pain Observation Tool, nociceptive flexion reflex and pupillary dilatation reflex as predictors of behavioural reactions to nociceptive procedures in critically ill patients unable to self-report pain
Topics: Adult; Analgesics, Opioid; Critical Care; Critical Illness; Dilatation; Humans; Nociception; Pain; P | 2022 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Letter to the Editor: "The incidence of propofol infusion syndrome in critically-ill patients".
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypnotics and Sedatives; Incidence; Infusions, I | 2023 |
Dexmedetomidine and Propofol Sedation in Critically Ill Patients: How Much Is Too Much?
Topics: Cohort Studies; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol | 2023 |
Dexmedetomidine and Propofol Sedation in Critically Ill Patients: How Much Is Too Much?
Topics: Cohort Studies; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol | 2023 |
Dexmedetomidine and Propofol Sedation in Critically Ill Patients: How Much Is Too Much?
Topics: Cohort Studies; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol | 2023 |
Dexmedetomidine and Propofol Sedation in Critically Ill Patients: How Much Is Too Much?
Topics: Cohort Studies; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol | 2023 |
Hypertriglyceridemia as a Cause of Continuous Renal Replacement Therapy Circuit Clotting: A Case Series.
Topics: Acute Kidney Injury; Anticoagulants; Blood Coagulation; Continuous Renal Replacement Therapy; Critic | 2023 |
Restricted Polypharmacy Compared to Usual Care in Mechanically Ventilated Patients: A Retrospective Cohort Study.
Topics: Adult; Critical Illness; Humans; Hypnotics and Sedatives; Intensive Care Units; Polypharmacy; Propof | 2023 |
Predicting favorable response to intravenous morphine in pediatric critically ill cardiac patients.
Topics: Analgesics; Child; Critical Illness; Humans; Hypnotics and Sedatives; Infant; Morphine; Propofol; Re | 2023 |
Evaluation of Atypical Antipsychotics for the Facilitation of Weaning Sedation in Mechanically Ventilated Critically Ill Patients.
Topics: Analgesics, Opioid; Antipsychotic Agents; Critical Illness; Female; Humans; Hypnotics and Sedatives; | 2024 |
Comparison of nasotracheal versus orotracheal intubation for sedation, assisted spontaneous breathing, mobilization, and outcome in critically ill patients: an exploratory retrospective analysis.
Topics: Critical Illness; Humans; Hypnotics and Sedatives; Intensive Care Units; Intubation, Intratracheal; | 2023 |
Co-induction with a vasopressor "chaser" to mitigate propofol-induced hypotension when intubating critically ill/frail patients-A questionable practice.
Topics: Aged; Anesthetics, Intravenous; Critical Illness; Drug Administration Schedule; Ephedrine; Frail Eld | 2019 |
Propofol infusion syndrome; are high doses always required?
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Chemical | 2020 |
Improvement in Protein Delivery for Critically Ill Patients Requiring High-Dose Propofol Therapy and Enteral Nutrition.
Topics: Adolescent; Adult; Critical Illness; Energy Intake; Enteral Nutrition; Humans; Intensive Care Units; | 2021 |
Does prolonged propofol sedation of mechanically ventilated COVID-19 patients contribute to critical illness myopathy?
Topics: Animals; Betacoronavirus; Coronavirus Infections; COVID-19; Critical Illness; Humans; Hypnotics and | 2020 |
DEXmedetomidine compared to PROpofol in NEurocritical Care [DEXPRONE]: A multicenter retrospective evaluation of clinical utility and safety.
Topics: Adult; Aged; Bradycardia; Critical Care; Critical Illness; Dexmedetomidine; Female; Humans; Hypnotic | 2020 |
Propofol infusion syndrome in severe COVID-19.
Topics: Betacoronavirus; Conscious Sedation; Coronavirus Infections; COVID-19; Critical Illness; Humans; Hyp | 2020 |
Propofol and SARS-CoV-2 infection.
Topics: Anesthetics, Intravenous; Coronavirus Infections; COVID-19; Critical Illness; Drug Repositioning; Hu | 2020 |
Observational study evaluating the nutritional impact of changing from 1% to 2% propofol in a cardiothoracic adult critical care unit.
Topics: Adult; Critical Care; Critical Illness; Energy Intake; Humans; Intensive Care Units; Nutritional Req | 2021 |
Comparison of isoflurane and propofol sedation in critically ill COVID-19 patients-a retrospective chart review.
Topics: Conscious Sedation; COVID-19; Critical Illness; Humans; Hypnotics and Sedatives; Intensive Care Unit | 2021 |
Does Propofol Sedation Contribute to Overall Energy Provision in Mechanically Ventilated Critically Ill Adults? A Retrospective Observational Study.
Topics: Adult; Aged; Critical Care; Critical Illness; Female; Hospital Mortality; Humans; Hypnotics and Seda | 2018 |
Propofol sedation substantially increases the caloric and lipid intake in critically ill patients.
Topics: Critical Care; Critical Illness; Energy Intake; Enteral Nutrition; Humans; Hypnotics and Sedatives; | 2017 |
Incidence and risk factors for urinary retention in critically ill patients.
Topics: Catheters, Indwelling; Critical Illness; Female; Humans; Hypnotics and Sedatives; Incidence; Intensi | 2019 |
Effects From Continuous Infusions of Dexmedetomidine and Propofol on Hemodynamic Stability in Critically Ill Adult Patients With Septic Shock.
Topics: Adult; Aged; Bradycardia; Critical Care; Critical Care Outcomes; Critical Illness; Dexmedetomidine; | 2020 |
Characterization of post-surgical critical patients with infections associated with healthcare after prolonged perfusion of remifentanil.
Topics: Aged; Analgesics, Opioid; Anesthesia, Local; APACHE; Critical Illness; Cross Infection; Deep Sedatio | 2018 |
[Comparison of sedative effects of propofol and midazolam on emergency critical patients on mechanical ventilation].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Care; Critical Illness; Female; Humans; Hypnoti | 2013 |
Propofol infusion syndrome: a lethal condition in critically injured patients eliminated by a simple screening protocol.
Topics: Acidosis; Acute Kidney Injury; Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Cohort Studies | 2014 |
Safety of Propofol as an Induction Agent for Urgent Endotracheal Intubation in the Medical Intensive Care Unit.
Topics: Aged; Anesthetics, Intravenous; Attitude of Health Personnel; Case-Control Studies; Checklist; Clini | 2015 |
Propofol-associated urine discolouration in critically ill patients-case reports.
Topics: Adult; Color; Critical Illness; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle | 2014 |
Efficacy and safety of analgosedation with fentanyl compared with traditional sedation with propofol.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Intravenous; Critical Illness; Female; Fen | 2014 |
Cost effectiveness of a benzodiazepine vs a nonbenzodiazepine-based sedation regimen for mechanically ventilated, critically ill adults.
Topics: Adult; Benzodiazepines; Clinical Protocols; Cost-Benefit Analysis; Critical Illness; Dexmedetomidine | 2014 |
Comparison of Dexmedetomidine Versus Propofol on Hospital Costs and Length of Stay.
Topics: Adult; Aged; Conscious Sedation; Critical Care; Critical Illness; Dexmedetomidine; Female; Hospital | 2016 |
Correlation of patient-reported outcomes of sedation and sedation assessment scores in critically ill patients.
Topics: Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; Female; Humans; Hypnotics and Sedative | 2014 |
Emergency nurses practices in assessing and administering continuous intravenous sedation for critically ill adult patients: a retrospective record review'.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Conscious Sedation; Critical Il | 2015 |
Patient-centered endpoints in trials of ICU sedation.
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Midazolam; Propofol | 2014 |
Ketamine and propofol combination ("ketofol") for endotracheal intubations in critically ill patients: a case series.
Topics: Adult; Aged; Anesthetics, Dissociative; Anesthetics, Intravenous; Critical Illness; Drug Therapy, Co | 2015 |
Survival after long-term isoflurane sedation as opposed to intravenous sedation in critically ill surgical patients: Retrospective analysis.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Critical Illness; | 2016 |
Survival after long-term isoflurane sedation as opposed to intravenous sedation in critically ill surgical patients: Retrospective analysis.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Critical Illness; | 2016 |
Survival after long-term isoflurane sedation as opposed to intravenous sedation in critically ill surgical patients: Retrospective analysis.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Critical Illness; | 2016 |
Survival after long-term isoflurane sedation as opposed to intravenous sedation in critically ill surgical patients: Retrospective analysis.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Critical Illness; | 2016 |
Propofol, midazolam, vancomycin and cyclosporine therapeutic drug monitoring in extracorporeal membrane oxygenation circuits primed with whole human blood.
Topics: Anti-Infective Agents; Blood; Critical Illness; Cyclosporine; Drug Monitoring; Extracorporeal Membra | 2015 |
Renal Outcomes in Critically Ill Patients Receiving Propofol or Midazolam.
Topics: Acute Kidney Injury; Aged; Anesthetics, Intravenous; Cohort Studies; Critical Illness; Female; Human | 2015 |
Outcomes of Patients with Alcohol Withdrawal Syndrome Treated with High-Dose Sedatives and Deferred Intubation.
Topics: Adult; Alcohol Withdrawal Seizures; APACHE; Central Nervous System Depressants; Cohort Studies; Crit | 2016 |
Prolonged propofol infusion for mechanically ventilated children.
Topics: Adolescent; Critical Care; Critical Illness; Female; Humans; Hypnotics and Sedatives; Infant; Infusi | 2016 |
Impact of different sedation protocols and perioperative procedures on patients admitted to the intensive care unit after maxillofacial tumor surgery of the lower jaw: A retrospective study.
Topics: Critical Illness; Drug Costs; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; | 2016 |
The relationship between sedative drug utilization and outcomes in critically ill patients undergoing mechanical ventilation.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Benzodiazepines; Critical Illness; Dexmedetomidine; Dru | 2016 |
Propofol as a Risk Factor for ICU-Acquired Weakness in Septic Patients with Acute Respiratory Failure.
Topics: Adult; Aged; Cohort Studies; Critical Illness; Electronic Health Records; Female; Humans; Hypnotics | 2017 |
The use of "ketofol" (ketamine-propofol admixture) infusion in conjunction with regional anaesthesia.
Topics: Aged; Aged, 80 and over; Anesthesia, Conduction; Anesthetics, Combined; Blood Pressure; Critical Ill | 2009 |
Evaluations of physiologic reactivity and reflexive behaviors during noxious procedures in sedated critically ill patients.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Blood Pressure; Cardiac Surgical Procedure | 2009 |
Propofol infusion syndrome in patients with refractory status epilepticus: an 11-year clinical experience.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Critical Illness; Female; Human | 2009 |
Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter study.
Topics: Academic Medical Centers; Adult; Aged; Anesthetics, Intravenous; Arrhythmias, Cardiac; Critical Illn | 2009 |
Propofol infusion syndrome: difficult to recognize, difficult to study.
Topics: Critical Illness; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Propofol; Syndrome | 2009 |
Effects of propofol and dexmedetomidine on indocyanine green elimination assessed with LIMON to patients with early septic shock: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Coloring Agents; Critical Illness; Dexmedetomidine; Female; Hemodyna | 2009 |
The propofol infusion syndrome: more puzzling evidence on a complex and poorly characterized disorder.
Topics: Adult; Child; Critical Illness; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Multicenter | 2009 |
Parenteral nutrition in the critically ill patient.
Topics: Calcium Channel Blockers; Critical Illness; Energy Intake; Fat Emulsions, Intravenous; Humans; Hypno | 2010 |
Defining critical illness-related corticosteroid insufficiency: one step forward!
Topics: Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Aldosterone; Animals; Conscious | 2010 |
Bispectral index correlates well with Richmond agitation sedation scale in mechanically ventilated critically ill patients.
Topics: Adolescent; Adult; Blood Gas Analysis; Conscious Sedation; Consciousness Monitors; Critical Care; Cr | 2010 |
Evaluation of dexmedetomidine: safety and clinical outcomes in critically ill trauma patients.
Topics: Adult; Analgesics; Antipsychotic Agents; Chi-Square Distribution; Critical Illness; Dexmedetomidine; | 2011 |
Impact of a national propofol shortage on duration of mechanical ventilation at an academic medical center.
Topics: Academic Medical Centers; Adult; Aged; Critical Illness; Female; Hospital Mortality; Humans; Hypnoti | 2012 |
Hypertriglyceridemia: a potential side effect of propofol sedation in critical illness.
Topics: Aged; Critical Illness; Drug Carriers; Fat Emulsions, Intravenous; Female; Humans; Hypertriglyceride | 2012 |
Continuous propofol infusion in 142 critically ill children.
Topics: Acidosis; Adolescent; Analgesics; Cardiovascular Agents; Child; Child, Preschool; Comorbidity; Criti | 2002 |
Propofol syndrome in children.
Topics: Acidosis; Age Factors; Anesthetics, Intravenous; Child; Conscious Sedation; Critical Illness; Hepato | 2003 |
Propofol syndrome in children.
Topics: Age Factors; Anesthetics, Intravenous; Child; Child, Preschool; Conscious Sedation; Contraindication | 2003 |
Comment: propofol infusion syndrome in critically ill patients.
Topics: Adult; Anesthetics, Intravenous; Child; Critical Illness; Humans; Injections, Intravenous; Propofol; | 2003 |
The FDA warning against prolonged sedation with propofol in children remains warranted.
Topics: Child; Child, Preschool; Contraindications; Critical Illness; Fatty Acids; Hospital Mortality; Human | 2003 |
Continuous propofol infusion in 142 critically ill children.
Topics: Anesthetics, Intravenous; Child; Critical Care; Critical Illness; Humans; Propofol | 2003 |
The presence of working memory without explicit recall in a critically ill patient.
Topics: Adolescent; Anesthesia, General; Anesthetics, Intravenous; Critical Illness; Depressive Disorder; El | 2004 |
Case report: requirement of supplemental morphine during sedation with propofol in a critically ill patient undergoing hemodiafiltration.
Topics: Adolescent; Conscious Sedation; Critical Illness; Hemodiafiltration; Humans; Male; Morphine; Propofo | 2003 |
Interaction between infusion equipment resulting in drug overdose in a critically ill patient.
Topics: Acute Kidney Injury; Adolescent; Analgesics, Opioid; Critical Illness; Drug Overdose; Equipment Fail | 2005 |
Procedural sedation of critically ill patients in the emergency department.
Topics: Adult; Conscious Sedation; Critical Illness; Emergency Service, Hospital; Etomidate; Female; Humans; | 2005 |
Practice of sedation and analgesia in German intensive care units: results of a national survey.
Topics: Analgesia; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Clonidine; Critical Illness; Data In | 2005 |
Myoglobinemia and propofol infusion.
Topics: Adult; Anesthetics, Intravenous; Chlorine; Critical Illness; Humans; Male; Myoglobin; Near Drowning; | 2005 |
Medications to provide cooperation in the critically ill pediatric patient: a rose with a thorn.
Topics: Adrenergic alpha-Agonists; Adult; Child; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Se | 2005 |
Pharmacoeconomic modeling of lorazepam, midazolam, and propofol for continuous sedation in critically ill patients.
Topics: Costs and Cost Analysis; Critical Illness; Decision Support Techniques; Economics, Pharmaceutical; H | 2005 |
Effects of neuromuscular block on systemic and cerebral hemodynamics and bispectral index during moderate or deep sedation in critically ill patients.
Topics: Aged; Anesthesia; Cerebrovascular Circulation; Conscious Sedation; Critical Illness; Electromyograph | 2006 |
Disease severity is a major determinant for the pharmacodynamics of propofol in critically ill patients.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Dose-Response Relationship, Drug; Female; Humans; | 2008 |
The effects of sedation on gastric emptying and intra-gastric meal distribution in critical illness.
Topics: Body Mass Index; Critical Illness; Dietary Sucrose; Enteral Nutrition; Female; Food, Formulated; Gas | 2008 |
Propofol and intralipid cause creaming of serum from critically ill patients.
Topics: Acute-Phase Proteins; Adult; Aged; Anesthesia, Intravenous; Critical Illness; Dose-Response Relation | 1994 |
Haemodynamic and oxygen transport effects of propofol infusion in critically ill adults.
Topics: Aged; Aged, 80 and over; Biological Transport; Critical Illness; Hemodynamics; Humans; Hypnotics and | 1994 |
Do infusions of midazolam and propofol pose an infection risk to critically ill patients?
Topics: Bacterial Infections; Critical Illness; Drug Contamination; Equipment Contamination; Humans; Infusio | 1994 |
Co-sedation in the critically ill.
Topics: Adult; Conscious Sedation; Critical Illness; Drug Synergism; Female; Humans; Male; Midazolam; Middle | 1995 |
Hypertriglyceridaemia associated with propofol sedation in critically ill patients.
Topics: Adolescent; Adult; Critical Illness; Female; Humans; Hypertriglyceridemia; Hypnotics and Sedatives; | 1996 |
[Prolonged propofol (Diprivan) infusion for sedation in the critically ill].
Topics: Aged; Anesthetics, Combined; Anesthetics, Intravenous; Conscious Sedation; Critical Illness; Fentany | 1996 |
Pharmacologic influence on nutrition support therapy: use of propofol in a patient receiving combined enteral and parenteral nutrition support.
Topics: Adolescent; Critical Illness; Drug Monitoring; Female; Humans; Hypertriglyceridemia; Hypnotics and S | 1996 |
Sedating patients in intensive care units.
Topics: Analgesics, Opioid; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Conscious Sedation; | 1997 |
Propofol versus midazolam in critically ill patients.
Topics: Conscious Sedation; Critical Illness; Humans; Hypnotics and Sedatives; Midazolam; Neurologic Examina | 1997 |
Propofol and midazolam for sedation of the critically ill.
Topics: Critical Illness; Humans; Hypnotics and Sedatives; Midazolam; Propofol | 1997 |
Serum protein binding of propofol in critically ill patients.
Topics: Adult; Aged; Anesthetics, Intravenous; Blood Proteins; Critical Illness; Female; Humans; Male; Middl | 1997 |
Effects of intravenous anesthetics on bacterial elimination in human blood in vitro.
Topics: Adult; Anesthetics, Dissociative; Anesthetics, Intravenous; Bacteremia; Blood Bactericidal Activity; | 1998 |
Propofol and hypertriglyceridemia: no problem?
Topics: Anesthetics, Intravenous; Critical Illness; Humans; Hypertriglyceridemia; Propofol; Triglycerides | 1999 |
Cortical arousal in critically ill patients: an evoked response study.
Topics: Analysis of Variance; Anesthetics, Intravenous; Arousal; Critical Illness; Evoked Potentials, Audito | 2000 |
Combination propofol-ketamine anaesthesia in sick neonates.
Topics: Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; | 2001 |
The safety and efficacy of propofol containing EDTA: a randomised clinical trial programme focusing on cation and trace metal homeostasis in critically ill patients.
Topics: Anesthetics, Intravenous; Cations; Chelating Agents; Consumer Product Safety; Critical Illness; Edet | 2000 |
Sedation assessment in critically ill patients with bispectral index.
Topics: Body Temperature; Critical Care; Critical Illness; Electroencephalography; Female; Humans; Hypnotics | 2002 |
Critically ill patients and fat emulsions.
Topics: Critical Care; Critical Illness; Fat Emulsions, Intravenous; Humans; Lung Diseases; Propofol | 1992 |