Page last updated: 2024-11-03

propofol and Colorectal Cancer

propofol has been researched along with Colorectal Cancer in 29 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
" This study hypothesized that propofol-based anesthesia would have fewer harmful effects on immune cells than volatile anesthetics-based anesthesia during colorectal cancer surgery."9.51Expression Profiles of Immune Cells after Propofol or Sevoflurane Anesthesia for Colorectal Cancer Surgery: A Prospective Double-blind Randomized Trial. ( Hwang, DY; Kim, SH; Koh, SE; Oh, CS; Park, HJ; Piao, L; Sohn, KM, 2022)
"To assess the factors associated with adenoma detection in propofol-sedated patients."9.30Factors Associated With Adenoma Detection in Propofol-sedated Patients. ( Dong, T; Hsieh, YH; Hu, CT; Jia, H; Koo, M; Leung, FW; Pan, Y; Tseng, CW; Zhang, L, 2019)
"To compare the effect of propofol and sevoflurane on perioperative immunity and surgical outcomes in patients undergoing laparoscopic radical resection of colorectal cancer."9.20[The effect of propofol and sevoflurane on the perioperative immunity in patients under laparoscopic radical resection of colorectal cancer]. ( Chen, Y; Liang, M; Zhou, D; Zhu, Y, 2015)
"Chemotherapy had no effect on the Ce of propofol for LVC and LOC in patients with colorectal cancer."8.12Effect of chemotherapy on effect-site concentration of propofol for loss of consciousness in patients with colorectal cancer. ( Cho, Y; Choi, Y; Ki, S; Kim, M; Lee, J; Lim, S, 2022)
"Propofol has recently been attracted increasing attention for its anti-tumor property in cancers, including colorectal cancer (CRC)."8.02Propofol suppresses colorectal cancer development by the circ-PABPN1/miR-638/SRSF1 axis. ( Liu, Y; Zhao, A, 2021)
"Circulating vesicles were investigated in a prospective, matched-case pilot study in two cohorts of colorectal cancer patients receiving either propofol (n = 8) or sevoflurane (n = 9), matched for tumor stage and location."7.96Propofol and Sevoflurane Differentially Impact MicroRNAs in Circulating Extracellular Vesicles during Colorectal Cancer Resection: A Pilot Study. ( Brandes, F; Buschmann, D; Chouker, A; Ganschow, P; Lindemann, A; Maerte, M; Pfaffl, MW; Reithmair, M; Schelling, G, 2020)
"Propofol, an extensively used intravenous anesthetic agents during cancer resection surgery, has been confirmed to execute anti-tumor effect on multiple cancers, including colorectal cancer (CRC)."7.96Propofol suppresses proliferation and metastasis of colorectal cancer cells by regulating miR-124-3p.1/AKT3. ( Dong, W; Li, Y; Xiao, G; Yang, H, 2020)
"To investigate the effect of propofol on glucose metabolism in colorectal cancer cells and in an in vivo xenograft model."7.88Propofol Disrupts Aerobic Glycolysis in Colorectal Cancer Cells via Inactivation of the NMDAR-CAMKII-ERK Pathway. ( Chen, X; Miao, C; Sun, P; Wu, Q; Zhao, Y; Zhu, M, 2018)
"Propofol sedation can be safely applied to colorectal cancer screening outpatients."7.75Propofol sedation in a colorectal cancer screening outpatient cohort. ( Bonanomi, GA; Boninsegni, P; Castiglione, G; Chelazzi, C; Consales, G; De Gaudio, AR, 2009)
"Surgery for colorectal cancer (CRC) can cause damage to the intestinal mucosal barrier and lead to bacterial invasion."5.62Propofol Regulates the TLR4/NF-κB Pathway Through miRNA-155 to Protect Colorectal Cancer Intestinal Barrier. ( Gao, Y; Han, C; Han, T; Ni, X; Sun, H; Yang, X; Zhang, D, 2021)
" This study hypothesized that propofol-based anesthesia would have fewer harmful effects on immune cells than volatile anesthetics-based anesthesia during colorectal cancer surgery."5.51Expression Profiles of Immune Cells after Propofol or Sevoflurane Anesthesia for Colorectal Cancer Surgery: A Prospective Double-blind Randomized Trial. ( Hwang, DY; Kim, SH; Koh, SE; Oh, CS; Park, HJ; Piao, L; Sohn, KM, 2022)
"However, the impact of propofol on colorectal cancer and IL-13 induced epithelial-mesenchymal transition remains unknown."5.48Propofol prevents IL-13-induced epithelial-mesenchymal transition in human colorectal cancer cells. ( Su, Z; Tao, W; Xu, K, 2018)
"To assess the factors associated with adenoma detection in propofol-sedated patients."5.30Factors Associated With Adenoma Detection in Propofol-sedated Patients. ( Dong, T; Hsieh, YH; Hu, CT; Jia, H; Koo, M; Leung, FW; Pan, Y; Tseng, CW; Zhang, L, 2019)
"To compare the effect of propofol and sevoflurane on perioperative immunity and surgical outcomes in patients undergoing laparoscopic radical resection of colorectal cancer."5.20[The effect of propofol and sevoflurane on the perioperative immunity in patients under laparoscopic radical resection of colorectal cancer]. ( Chen, Y; Liang, M; Zhou, D; Zhu, Y, 2015)
" The aim of this study was to establish and compare differences in inflammatory response among colorectal cancer surgery patients receiving either total intravenous anesthesia (TIVA) with propofol and remifentanil or inhalational anesthesia (INHAL) with sevoflurane and fentanyl."5.15Inflammatory response in patients undergoing colorectal cancer surgery: the effect of two different anesthetic techniques. ( Bengtson, JP; Bengtsson, A; Kvarnström, A; Sarbinowski, R; Tylman, M, 2011)
"Chemotherapy had no effect on the Ce of propofol for LVC and LOC in patients with colorectal cancer."4.12Effect of chemotherapy on effect-site concentration of propofol for loss of consciousness in patients with colorectal cancer. ( Cho, Y; Choi, Y; Ki, S; Kim, M; Lee, J; Lim, S, 2022)
"Propofol has recently been attracted increasing attention for its anti-tumor property in cancers, including colorectal cancer (CRC)."4.02Propofol suppresses colorectal cancer development by the circ-PABPN1/miR-638/SRSF1 axis. ( Liu, Y; Zhao, A, 2021)
"Circulating vesicles were investigated in a prospective, matched-case pilot study in two cohorts of colorectal cancer patients receiving either propofol (n = 8) or sevoflurane (n = 9), matched for tumor stage and location."3.96Propofol and Sevoflurane Differentially Impact MicroRNAs in Circulating Extracellular Vesicles during Colorectal Cancer Resection: A Pilot Study. ( Brandes, F; Buschmann, D; Chouker, A; Ganschow, P; Lindemann, A; Maerte, M; Pfaffl, MW; Reithmair, M; Schelling, G, 2020)
"Propofol, an extensively used intravenous anesthetic agents during cancer resection surgery, has been confirmed to execute anti-tumor effect on multiple cancers, including colorectal cancer (CRC)."3.96Propofol suppresses proliferation and metastasis of colorectal cancer cells by regulating miR-124-3p.1/AKT3. ( Dong, W; Li, Y; Xiao, G; Yang, H, 2020)
"To investigate the effect of propofol on glucose metabolism in colorectal cancer cells and in an in vivo xenograft model."3.88Propofol Disrupts Aerobic Glycolysis in Colorectal Cancer Cells via Inactivation of the NMDAR-CAMKII-ERK Pathway. ( Chen, X; Miao, C; Sun, P; Wu, Q; Zhao, Y; Zhu, M, 2018)
"Propofol sedation can be safely applied to colorectal cancer screening outpatients."3.75Propofol sedation in a colorectal cancer screening outpatient cohort. ( Bonanomi, GA; Boninsegni, P; Castiglione, G; Chelazzi, C; Consales, G; De Gaudio, AR, 2009)
"Propofol was titrated to a level of deep sedation and propofol combined with midazolam was used for moderate sedation."2.74CO2 insufflation during colonoscopy decreases post-interventional pain in deeply sedated patients: a randomized controlled trial. ( Akan, B; Dirlea, D; Karner-Hanusch, J; Mikola, B; Mittlböck, M; Rieder, E; Riss, S; Weiser, FA, 2009)
"Surgery for colorectal cancer (CRC) can cause damage to the intestinal mucosal barrier and lead to bacterial invasion."1.62Propofol Regulates the TLR4/NF-κB Pathway Through miRNA-155 to Protect Colorectal Cancer Intestinal Barrier. ( Gao, Y; Han, C; Han, T; Ni, X; Sun, H; Yang, X; Zhang, D, 2021)
"However, the impact of propofol on colorectal cancer and IL-13 induced epithelial-mesenchymal transition remains unknown."1.48Propofol prevents IL-13-induced epithelial-mesenchymal transition in human colorectal cancer cells. ( Su, Z; Tao, W; Xu, K, 2018)
"Anesthetics are unavoidable to colorectal cancer (CRC) patients who underwent surgical treatment."1.43Differential role of intravenous anesthetics in colorectal cancer progression: implications for clinical application. ( Chen, Y; Deng, F; Ouyang, M; Sun, X; Tang, J; Tao, T; Wang, X; Xu, L; Yao, X; Zhao, L, 2016)
" Except for benzodiazepines, which were dosed higher in women than men, equal doses of sedation were given to female and male patients."1.42Practice patterns of sedation for colonoscopy. ( Childers, RE; Sonnenberg, A; Williams, JL, 2015)
" BIS scores, sedation scores, and propofol dosing were correlated."1.32An initial investigation of bispectral monitoring as an adjunct to nurse-administered propofol sedation for colonoscopy. ( Chen, SC; Rex, DK, 2004)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (10.34)29.6817
2010's16 (55.17)24.3611
2020's10 (34.48)2.80

Authors

AuthorsStudies
Ki, S1
Cho, Y1
Choi, Y1
Lim, S1
Kim, M1
Lee, J1
Oh, CS1
Park, HJ1
Piao, L1
Sohn, KM1
Koh, SE1
Hwang, DY1
Kim, SH1
Sui, Y2
Wang, Q2
Chen, HH1
Lu, JH1
Wen, Q2
Wang, ZZ1
Wang, GF1
Jia, H3
Xiao, T1
Wang, NP1
Hao, JL1
Zhang, YP1
Cao, FZ1
Wu, XP1
Chen, X3
Zheng, Y1
Lv, J1
Wang, H1
Wang, Z2
Wang, G1
Cao, F1
Wang, N1
Hao, J1
Zhang, Y1
Wu, X1
Chen, H1
Lu, J1
Oh, TK1
Jo, H1
Song, IA1
Buschmann, D1
Brandes, F1
Lindemann, A1
Maerte, M1
Ganschow, P1
Chouker, A1
Schelling, G1
Pfaffl, MW1
Reithmair, M1
Li, Y1
Dong, W1
Yang, H1
Xiao, G1
Gao, Y1
Han, T1
Han, C1
Sun, H1
Yang, X1
Zhang, D1
Ni, X1
Zhao, A1
Liu, Y1
Bugajski, M1
Wieszczy, P1
Hoff, G1
Rupinski, M1
Regula, J1
Kaminski, MF1
Pace, D1
Borgaonkar, M1
Xu, K1
Tao, W1
Su, Z1
Wu, Q1
Sun, P1
Zhao, Y1
Zhu, M1
Miao, C1
Salgado, TM1
Fernandez-Llimos, F1
Koo, M2
Hsieh, YH2
Tseng, CW2
Hu, CT2
Zhang, L1
Dong, T1
Pan, Y1
Leung, FW2
Prazeres, F1
Ren, YL1
Zhang, W1
Tian, K1
Kang, Y1
Deng, L1
Liu, H1
Li, H1
Zhao, G1
Childers, RE1
Williams, JL1
Sonnenberg, A1
Chen, Y2
Liang, M1
Zhu, Y1
Zhou, D1
Deng, F1
Ouyang, M1
Wang, X1
Yao, X1
Tao, T1
Sun, X1
Xu, L1
Tang, J1
Zhao, L1
Riss, S1
Akan, B1
Mikola, B1
Rieder, E1
Karner-Hanusch, J1
Dirlea, D1
Mittlböck, M1
Weiser, FA1
Chelazzi, C1
Consales, G1
Boninsegni, P1
Bonanomi, GA1
Castiglione, G1
De Gaudio, AR1
Cardin, F1
Minicuci, N1
Andreotti, A1
Pinetti, E1
Campigotto, F1
Donà, BM1
Martella, B1
Terranova, O1
Tylman, M1
Sarbinowski, R1
Bengtson, JP1
Kvarnström, A1
Bengtsson, A1
Dumonceau, JM1
Hassan, C1
Rex, DK2
Cooper, GS1
Benamouzig, R1
Chen, SC1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Optimal Sequence in Same-day Bidirectional Endoscopy Under Deep Anesthesia Induced by Propofol Combined With Fentanyl: A Prospective Randomized Controlled ,Two Centers Trial[NCT04973878]544 participants (Anticipated)Interventional2021-07-30Not yet recruiting
Comparison of The Effects Of General Anesthesia and PECS Block Methods on Blood Leukocyte, Neutrophil, Lymphocyte, and Platelet Counts in Patients With Breast Cancer[NCT06151639]26 participants (Actual)Observational2022-08-01Completed
Polyp Detection and False Alarm Rates by Computer-Aided Analysis of Videos of Withdrawal Phase of Colonoscopy in a Randomized Controlled Trial of Water Exchange Versus Air Insufflation[NCT04727814]250 participants (Actual)Observational2020-08-01Active, not recruiting
Abdominal Compression Administered Early by the Colonoscopist Shortened Insertion Time of Water Exchange Colonoscopy[NCT03954561]120 participants (Actual)Interventional2017-05-15Completed
Evaluation of Artificial Intelligence for Adenoma Detection in Water Exchange Colonoscopy: the WEAID Randomized Controlled Trial (Water Exchange With Artificial Intelligence-assisted Detection)[NCT06173258]836 participants (Anticipated)Interventional2023-12-18Recruiting
A Randomized, Controlled Trial Comparing the Adenoma Detection Rate With Air Insufflation, Water Immersion and Water Exchange During Colonoscopy[NCT01894191]651 participants (Actual)Interventional2013-05-31Completed
Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant[NCT04541667]200 participants (Actual)Interventional2019-11-18Completed
Water Exchange Versus Carbon Dioxide Insufflation to Improve Colonoscopy Screening - a Randomized Controlled Trial[NCT01633333]473 participants (Actual)Interventional2012-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Reporting Abdominal Pain

Pain rating scales using FLACC and VAS will be used to assess self reported pain before and after the procedure (NCT04541667)
Timeframe: This will be assessed before and after the procedure

Interventionparticipants (Number)
Air for Luminal Inflation14
Carbon Dioxide for Luminal Inflation15

Number of Procedures With Elevated End-tidal CO2 Levels

Compare the peak end-tidal CO2 levels (>/= 60 mmHg) observed during endoscopy in children managed with endotracheal intubation or laryngeal mask airway using CO2 versus air (NCT04541667)
Timeframe: Measured from time of procedure start to time of procedure conclusion this lasts usually from 1-2.5 hours.

InterventionProcedures (Count of Units)
Air for Luminal Inflation8
Carbon Dioxide for Luminal Inflation21

Trials

7 trials available for propofol and Colorectal Cancer

ArticleYear
Expression Profiles of Immune Cells after Propofol or Sevoflurane Anesthesia for Colorectal Cancer Surgery: A Prospective Double-blind Randomized Trial.
    Anesthesiology, 2022, 03-01, Volume: 136, Issue:3

    Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Colorectal Neoplasms; Double-Blind Method;

2022
Factors Associated With Adenoma Detection in Propofol-sedated Patients.
    Journal of clinical gastroenterology, 2019, Volume: 53, Issue:7

    Topics: Adenoma; Adult; Aged; Colonoscopy; Colorectal Neoplasms; Female; Humans; Hypnotics and Sedatives; In

2019
[Effects of different anesthesia depth on stress response in elderly patients undergoing elective laparoscopic surgery for colorectal cancer].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2014, Volume: 34, Issue:5

    Topics: Adrenocorticotropic Hormone; Aged; Aged, 80 and over; Anesthesia, General; Blood Pressure; C-Reactiv

2014
[The effect of propofol and sevoflurane on the perioperative immunity in patients under laparoscopic radical resection of colorectal cancer].
    Zhonghua yi xue za zhi, 2015, Nov-10, Volume: 95, Issue:42

    Topics: CD4-CD8 Ratio; Colorectal Neoplasms; Humans; Killer Cells, Natural; Laparoscopy; Methyl Ethers; Post

2015
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion, and air insufflation.
    Gastrointestinal endoscopy, 2017, Volume: 86, Issue:1

    Topics: Adenoma; Age Factors; Aged; Air; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; H

2017
CO2 insufflation during colonoscopy decreases post-interventional pain in deeply sedated patients: a randomized controlled trial.
    Wiener klinische Wochenschrift, 2009, Volume: 121, Issue:13-14

    Topics: Abdominal Pain; Adult; Anti-Anxiety Agents; Body Mass Index; Carbon Dioxide; Colonoscopy; Colorectal

2009
CO2 insufflation during colonoscopy decreases post-interventional pain in deeply sedated patients: a randomized controlled trial.
    Wiener klinische Wochenschrift, 2009, Volume: 121, Issue:13-14

    Topics: Abdominal Pain; Adult; Anti-Anxiety Agents; Body Mass Index; Carbon Dioxide; Colonoscopy; Colorectal

2009
CO2 insufflation during colonoscopy decreases post-interventional pain in deeply sedated patients: a randomized controlled trial.
    Wiener klinische Wochenschrift, 2009, Volume: 121, Issue:13-14

    Topics: Abdominal Pain; Adult; Anti-Anxiety Agents; Body Mass Index; Carbon Dioxide; Colonoscopy; Colorectal

2009
CO2 insufflation during colonoscopy decreases post-interventional pain in deeply sedated patients: a randomized controlled trial.
    Wiener klinische Wochenschrift, 2009, Volume: 121, Issue:13-14

    Topics: Abdominal Pain; Adult; Anti-Anxiety Agents; Body Mass Index; Carbon Dioxide; Colonoscopy; Colorectal

2009
Inflammatory response in patients undergoing colorectal cancer surgery: the effect of two different anesthetic techniques.
    Minerva anestesiologica, 2011, Volume: 77, Issue:3

    Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intrave

2011

Other Studies

22 other studies available for propofol and Colorectal Cancer

ArticleYear
Effect of chemotherapy on effect-site concentration of propofol for loss of consciousness in patients with colorectal cancer.
    Korean journal of anesthesiology, 2022, Volume: 75, Issue:2

    Topics: Anesthesia, General; Anesthetics, Intravenous; Colorectal Neoplasms; Humans; Monitoring, Intraoperat

2022
Comparison of adenoma detection in different colorectal segments between deep-sedated and unsedated colonoscopy.
    Scientific reports, 2022, 09-12, Volume: 12, Issue:1

    Topics: Adenoma; Colonoscopy; Colorectal Neoplasms; Humans; Mass Screening; Propofol

2022
Comparison of missed adenomas in deep-sedated and unsedated colonoscopy: A multicenter retrospective study.
    European journal of internal medicine, 2023, Volume: 110

    Topics: Adenoma; Colonoscopy; Colorectal Neoplasms; Humans; Propofol; Retrospective Studies; Time Factors

2023
Propofol-based intravenous anesthesia is associated with improved survival outcomes after major cancer surgery: a nationwide cohort study in South Korea.
    Korean journal of anesthesiology, 2023, Volume: 76, Issue:5

    Topics: Adult; Anesthesia, Intravenous; Cohort Studies; Colorectal Neoplasms; Humans; Pancreatic Neoplasms;

2023
Propofol and Sevoflurane Differentially Impact MicroRNAs in Circulating Extracellular Vesicles during Colorectal Cancer Resection: A Pilot Study.
    Anesthesiology, 2020, Volume: 132, Issue:1

    Topics: Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Colorectal Neoplasms; Fe

2020
Propofol suppresses proliferation and metastasis of colorectal cancer cells by regulating miR-124-3p.1/AKT3.
    Biotechnology letters, 2020, Volume: 42, Issue:3

    Topics: Cell Proliferation; Colorectal Neoplasms; HCT116 Cells; Humans; MicroRNAs; Neoplasm Metastasis; Prop

2020
Propofol Regulates the TLR4/NF-κB Pathway Through miRNA-155 to Protect Colorectal Cancer Intestinal Barrier.
    Inflammation, 2021, Volume: 44, Issue:5

    Topics: Animals; Colorectal Neoplasms; Hypnotics and Sedatives; Inflammation Mediators; Intestinal Mucosa; M

2021
Propofol suppresses colorectal cancer development by the circ-PABPN1/miR-638/SRSF1 axis.
    Analytical biochemistry, 2021, 10-15, Volume: 631

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Fe

2021
Modifiable factors associated with patient-reported pain during and after screening colonoscopy.
    Gut, 2018, Volume: 67, Issue:11

    Topics: Benzodiazepines; Colonoscopy; Colorectal Neoplasms; Cross-Sectional Studies; Databases, Factual; Ear

2018
Deep sedation for colonoscopy is unnecessary and wasteful.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2018, 02-12, Volume: 190, Issue:6

    Topics: Anesthesiology; Anesthetics, Intravenous; Canada; Colonoscopy; Colorectal Neoplasms; Cost-Benefit An

2018
Propofol prevents IL-13-induced epithelial-mesenchymal transition in human colorectal cancer cells.
    Cell biology international, 2018, Volume: 42, Issue:8

    Topics: Antagomirs; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Epithelial-Me

2018
Propofol Disrupts Aerobic Glycolysis in Colorectal Cancer Cells via Inactivation of the NMDAR-CAMKII-ERK Pathway.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 46, Issue:2

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Tumor; Colorectal Neoplasms;

2018
Letter to the Editor: "Limited Health Literacy in Portugal Assessed with the Newest Vital Sign" by Dagmara Paiva and Colleagues. Acta Med Port. 2017;30(12):861-869.
    Acta medica portuguesa, 2018, 03-29, Volume: 31, Issue:3

    Topics: Colorectal Neoplasms; Health Literacy; Humans; Portugal; Propofol

2018
[Letter to the Editor Regarding the Article: "Oral Health - Factors of Non-Adherence to Dental Vouchers: A Case- Control Study" by Rita Filipe and Pedro Aguiar. Acta Med Port 2018 Jun;31(6):303-311.]
    Acta medica portuguesa, 2018, Sep-28, Volume: 31, Issue:9

    Topics: Case-Control Studies; Colorectal Neoplasms; Humans; Oral Health; Propofol; Records

2018
Propofol promotes apoptosis of colorectal cancer cells via alleviating the suppression of lncRNA HOXA11-AS on miRNA let-7i.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2020, Volume: 98, Issue:2

    Topics: Anesthetics, Intravenous; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Colorectal Neo

2020
Practice patterns of sedation for colonoscopy.
    Gastrointestinal endoscopy, 2015, Volume: 82, Issue:3

    Topics: Adenoma; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Biopsy; Black or African American; Cath

2015
Differential role of intravenous anesthetics in colorectal cancer progression: implications for clinical application.
    Oncotarget, 2016, Nov-22, Volume: 7, Issue:47

    Topics: Anesthetics, Intravenous; Animals; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Dexmedetom

2016
Propofol sedation in a colorectal cancer screening outpatient cohort.
    Minerva anestesiologica, 2009, Volume: 75, Issue:12

    Topics: Ambulatory Care; Anesthetics, Intravenous; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female;

2009
Maximizing the general success of cecal intubation during propofol sedation in a multi-endoscopist academic centre.
    BMC gastroenterology, 2010, Oct-20, Volume: 10

    Topics: Academic Medical Centers; Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Colo

2010
Nonanesthesiologist administration of propofol: it's all about money.
    Endoscopy, 2012, Volume: 44, Issue:5

    Topics: Anesthesiology; Anesthetics, Intravenous; Colonoscopy; Colorectal Neoplasms; Humans; Nurse Anestheti

2012
Endoscopist-directed propofol administration versus anesthesiologist assistance for colorectal cancer screening: a cost-effectiveness analysis.
    Endoscopy, 2012, Volume: 44, Issue:5

    Topics: Aged; Aged, 80 and over; Anesthesiology; Anesthetics, Intravenous; Colonoscopy; Colorectal Neoplasms

2012
An initial investigation of bispectral monitoring as an adjunct to nurse-administered propofol sedation for colonoscopy.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Anesthesia Recovery Period; Colonoscopy; Colorectal

2004