propofol has been researched along with Colonic Neoplasms in 23 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Patients in the left lateral arm showed lower apnea rates (9." | 5.20 | Patient position and hypoxemia during propofol sedation for colonoscopy: a randomized trial. ( Haller, B; Huth, M; Huth, R; Klare, P; Reindl, W; Schlag, C; Schmid, RM; von Delius, S; Weber, A, 2015) |
| "Use of a new ultrathin colonoscope was associated with reduced propofol consumption, lower patient sedation levels, and less pain than the standard colonoscope, but ileal intubation time was longer." | 5.17 | Propofol sedation for colonoscopy with a new ultrathin or a standard endoscope: a prospective randomized controlled study. ( Goeser, T; Holzapfel, B; Lehmacher, W; Mertens, J; Neuhaus, H; Schumacher, B; Terheggen, G; Toermer, T; Töx, U, 2013) |
| "We presented a case of a postoperative patient with low-flow priapism, possibly initiated by propofol-based anaesthesia or epidural anaesthesia." | 3.85 | Postoperative drug-induced priapism. ( Aarts, F; Corten, BJGA; Harms, AS; Vogelaar, J, 2017) |
| "To determine if anesthesiologist-monitored use of propofol results in improved detection of adenomas when compared with routine conscious sedation." | 3.77 | Conscious or unconscious: the impact of sedation choice on colon adenoma detection. ( Agresti, N; Ciofoaia, V; Fine, J; Gross, SA; Hale, WB; Metwally, M; O'Connor, R; Wallace, MB; Wang, Y, 2011) |
| "Propofol treatment promoted cell apoptosis and inhibited cell invasion in colon cancer cells, while the effects were reversed by HOTAIR overexpression." | 1.56 | Effects of propofol on colon cancer metastasis through STAT3/HOTAIR axis by activating WIF-1 and suppressing Wnt pathway. ( Li, CS; Lu, XH; Zhang, YF; Zhou, Y, 2020) |
| "Propofol can inhibit the proliferation, migration and invasion of human colon cancer cells by inhibiting JAK2/STAT3 signaling pathway." | 1.56 | Effects of propofol on invasion and migration of colon cancer cells and JAK2/STAT3 signaling pathway. ( Dong, T; Liang, B, 2020) |
| "Propofol anesthesia for colon cancer surgery is associated with better survival irrespective of tumor-node-metastasis stage." | 1.48 | Propofol-based Total Intravenous Anesthesia Is Associated with Better Survival Than Desflurane Anesthesia in Colon Cancer Surgery. ( Chang, YC; Huang, YS; Lai, HC; Lee, MS; Lin, C; Lin, KT; Lou, YS; Lu, CH; Wong, CS; Wu, ZF, 2018) |
| "MATERIAL AND METHODS Twenty colon cancer patients and 20 healthy subjects were included." | 1.48 | Propofol Promotes Activity and Tumor-Killing Ability of Natural Killer Cells in Peripheral Blood of Patients with Colon Cancer. ( Du, Y; Kong, M; Liu, D; Sun, X, 2018) |
| "The LoVo colon cancer cells were cultured with patient serum from both groups and the effects on proliferation, invasion and apoptosis were measured." | 1.43 | Effects of anaesthesia on proliferation, invasion and apoptosis of LoVo colon cancer cells in vitro. ( Chen, WK; Cheng, Q; Li, SY; Miao, CH; Ren, Y; Wang, SL; Xu, YJ, 2016) |
| "We have shown that human colon cancer cells are efficient in drug conjugation catalyzed by UDP-glucuronosyltransferases (UGTs) and now report on the role of glucuronidation in de novo resistance to two topoisomerase I inhibitors." | 1.32 | Glucuronidation as a mechanism of intrinsic drug resistance in human colon cancer: reversal of resistance by food additives. ( Boyd, G; Burchell, B; Cummings, J; Ethell, BT; Jardine, L; Jodrell, DI; Macpherson, JS; Smyth, JF, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 15 (65.22) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, YF | 1 |
| Li, CS | 1 |
| Zhou, Y | 1 |
| Lu, XH | 1 |
| Liang, B | 1 |
| Dong, T | 1 |
| Corten, BJGA | 1 |
| Aarts, F | 1 |
| Harms, AS | 1 |
| Vogelaar, J | 1 |
| Wu, ZF | 2 |
| Lee, MS | 1 |
| Wong, CS | 1 |
| Lu, CH | 1 |
| Huang, YS | 1 |
| Lin, KT | 1 |
| Lou, YS | 1 |
| Lin, C | 1 |
| Chang, YC | 1 |
| Lai, HC | 2 |
| Liu, D | 1 |
| Sun, X | 1 |
| Du, Y | 1 |
| Kong, M | 1 |
| Diaz Milian, R | 1 |
| Töx, U | 1 |
| Schumacher, B | 1 |
| Toermer, T | 1 |
| Terheggen, G | 1 |
| Mertens, J | 1 |
| Holzapfel, B | 1 |
| Lehmacher, W | 1 |
| Goeser, T | 1 |
| Neuhaus, H | 1 |
| Sadurní, M | 1 |
| Beltrán de Heredia, S | 1 |
| Dürsteler, C | 1 |
| Pérez-Ramos, A | 1 |
| Langohr, K | 1 |
| Escolano, F | 1 |
| Puig, MM | 1 |
| Liu, M | 1 |
| Wang, Q | 1 |
| Liu, F | 1 |
| Cheng, X | 1 |
| Wu, X | 1 |
| Wang, H | 1 |
| Wu, M | 1 |
| Ma, Y | 1 |
| Wang, G | 1 |
| Hao, H | 1 |
| Wang, Y | 2 |
| Linghu, E | 1 |
| Xu, YJ | 2 |
| Chen, WK | 2 |
| Zhu, Y | 1 |
| Wang, SL | 2 |
| Miao, CH | 2 |
| Klare, P | 1 |
| Huth, R | 1 |
| Haller, B | 1 |
| Huth, M | 1 |
| Weber, A | 1 |
| Schlag, C | 1 |
| Reindl, W | 1 |
| Schmid, RM | 1 |
| von Delius, S | 1 |
| Li, SY | 1 |
| Cheng, Q | 1 |
| Ren, Y | 1 |
| Ciechanowicz, SJ | 1 |
| Ma, D | 1 |
| Miao, Y | 1 |
| Zhang, Y | 1 |
| Wan, H | 1 |
| Chen, L | 1 |
| Wang, F | 1 |
| Metwally, M | 1 |
| Agresti, N | 1 |
| Hale, WB | 1 |
| Ciofoaia, V | 1 |
| O'Connor, R | 1 |
| Wallace, MB | 1 |
| Fine, J | 1 |
| Gross, SA | 1 |
| Cummings, J | 1 |
| Ethell, BT | 1 |
| Jardine, L | 1 |
| Boyd, G | 1 |
| Macpherson, JS | 1 |
| Burchell, B | 1 |
| Smyth, JF | 1 |
| Jodrell, DI | 1 |
| Salihoğlu, Z | 1 |
| Demiroluk, S | 1 |
| Görgün, E | 1 |
| Karaca, S | 1 |
| Ozçelik, F | 1 |
| Lee, DW | 1 |
| Chan, AC | 1 |
| Wong, SK | 1 |
| Li, AC | 1 |
| Sze, TS | 1 |
| Chung, SC | 1 |
| Kakinohana, M | 1 |
| Nakamura, S | 1 |
| Miyata, Y | 1 |
| Sugahara, K | 1 |
| Guibert Bayona, MA | 1 |
| Borque Martín, JL | 1 |
| Araújo Fernández, AM | 1 |
| Ruiz Ilundáin, G | 1 |
| Furuya, R | 1 |
| Hirai, A | 1 |
| Andoh, T | 1 |
| Kudoh, I | 1 |
| Okumura, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT02039453] | 160 participants (Anticipated) | Interventional | 2013-09-30 | Recruiting | |||
| A Prospective, Randomized, Controlled Trial to Compare the Effect of TIVA Propofol vs Sevoflurane Anaesthetic on Serumserum Biomarkers and on PBMCs in Patients Undergoing Breast Cancer Resection Surgery[NCT03005860] | 0 participants (Actual) | Interventional | 2017-01-01 | Withdrawn (stopped due to Funding could not be arranged, so the study was prematurely terminated) | |||
| [NCT02001792] | 412 participants (Actual) | Interventional | 2012-04-30 | Completed | |||
| Anesthesia and Immunological and Oxidative Stress in Relation to Abdominal Cancer Surgery[NCT03974984] | 0 participants (Actual) | Observational | 2020-06-04 | Withdrawn (stopped due to Not feasable due to logistics) | |||
| Improving Perioperative Pain Management for Laparoscopic Surgery Due to Colon Cancer Using the Ultrasound-guided Transmuscular Quadratus Lumborum Block. A Double Blind, Randomized, Placebo Controlled Trial.[NCT03570541] | Phase 4 | 69 participants (Actual) | Interventional | 2018-06-28 | Completed | ||
| Impact of Intraoperative Blood Pressure Management and Dexamethasone on Patient's Outcomes After Lung Cancer Surgery: A 2 × 2 Factorial Randomized Controlled Trial[NCT04209218] | 1,988 participants (Anticipated) | Interventional | 2020-04-07 | Recruiting | |||
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Long-term Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT02660411] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Completed | |||
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on 5-year Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT05343260] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 trials available for propofol and Colonic Neoplasms
| Article | Year |
|---|---|
Propofol sedation for colonoscopy with a new ultrathin or a standard endoscope: a prospective randomized controlled study.
Topics: Adenoma; Aged; Cecum; Colonic Neoplasms; Colonoscopes; Colonoscopy; Conscious Sedation; Female; Huma | 2013 |
Epidural vs. intravenous fentanyl during colorectal surgery using a double-blind, double-dummy design.
Topics: Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, General; A | 2013 |
Effect of thoracic epidural anaesthesia on serum vascular endothelial growth factor C and cytokines in patients undergoing anaesthesia and surgery for colon cancer.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenous; | 2014 |
Patient position and hypoxemia during propofol sedation for colonoscopy: a randomized trial.
Topics: Adenoma; Adult; Aged; Apnea; Colonic Neoplasms; Colonoscopy; Conscious Sedation; Female; Humans; Hyp | 2015 |
Effects of sevoflurane versus TIVA on gastric intramucosal pH and hemodynamic status in colon cancer surgery.
Topics: Analysis of Variance; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Co | 2003 |
The safety, feasibility, and acceptability of patient-controlled sedation for colonoscopy: prospective study.
Topics: Adolescent; Adult; Aged; Alfentanil; Analgesia, Patient-Controlled; Analysis of Variance; Colonic Ne | 2004 |
17 other studies available for propofol and Colonic Neoplasms
| Article | Year |
|---|---|
Effects of propofol on colon cancer metastasis through STAT3/HOTAIR axis by activating WIF-1 and suppressing Wnt pathway.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Colonic N | 2020 |
Effects of propofol on invasion and migration of colon cancer cells and JAK2/STAT3 signaling pathway.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Humans; Janus Kinase 2; Prop | 2020 |
Postoperative drug-induced priapism.
Topics: Anesthetics, Intravenous; Colonic Neoplasms; Diagnosis, Differential; Humans; Hypnotics and Sedative | 2017 |
Propofol-based Total Intravenous Anesthesia Is Associated with Better Survival Than Desflurane Anesthesia in Colon Cancer Surgery.
Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Cohort Studies; Colon; Colonic Neoplasms; D | 2018 |
Propofol Promotes Activity and Tumor-Killing Ability of Natural Killer Cells in Peripheral Blood of Patients with Colon Cancer.
Topics: China; Coculture Techniques; Colonic Neoplasms; Flow Cytometry; Humans; K562 Cells; Killer Cells, Na | 2018 |
Propofol and Outcome from Colon Cancer Surgery: Reply.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Colonic Neoplasms; Desflurane; Humans; Propofol | 2019 |
Propofol and Outcome from Colon Cancer Surgery: Comment.
Topics: Anesthetics, Intravenous; Colonic Neoplasms; Humans; Methyl Ethers; Propofol | 2019 |
UDP-glucuronosyltransferase 1A compromises intracellular accumulation and anti-cancer effect of tanshinone IIA in human colon cancer cells.
Topics: Abietanes; Anesthetics, Intravenous; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Colonic Ne | 2013 |
Standard or ultrathin device for colonoscopy?
Topics: Adenoma; Colonic Neoplasms; Colonoscopy; Conscious Sedation; Female; Humans; Hypnotics and Sedatives | 2014 |
Effects of anaesthesia on proliferation, invasion and apoptosis of LoVo colon cancer cells in vitro.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia; Anesthesia, Epidural; Anesthetics, Inhalation; Anestheti | 2016 |
Anaesthesia for oncological surgery - can it really influence cancer recurrence?
Topics: Anesthesia; Apoptosis; Cell Proliferation; Colonic Neoplasms; Female; Humans; Male; Methyl Ethers; P | 2016 |
Anaesthesia for oncological surgery - can it really influence cancer recurrence?
Topics: Anesthesia; Apoptosis; Cell Proliferation; Colonic Neoplasms; Female; Humans; Male; Methyl Ethers; P | 2016 |
Anaesthesia for oncological surgery - can it really influence cancer recurrence?
Topics: Anesthesia; Apoptosis; Cell Proliferation; Colonic Neoplasms; Female; Humans; Male; Methyl Ethers; P | 2016 |
Anaesthesia for oncological surgery - can it really influence cancer recurrence?
Topics: Anesthesia; Apoptosis; Cell Proliferation; Colonic Neoplasms; Female; Humans; Male; Methyl Ethers; P | 2016 |
Anaesthesia for oncological surgery - can it really influence cancer recurrence?
Topics: Anesthesia; Apoptosis; Cell Proliferation; Colonic Neoplasms; Female; Humans; Male; Methyl Ethers; P | 2016 |
Anaesthesia for oncological surgery - can it really influence cancer recurrence?
Topics: Anesthesia; Apoptosis; Cell Proliferation; Colonic Neoplasms; Female; Humans; Male; Methyl Ethers; P | 2016 |
Anaesthesia for oncological surgery - can it really influence cancer recurrence?
Topics: Anesthesia; Apoptosis; Cell Proliferation; Colonic Neoplasms; Female; Humans; Male; Methyl Ethers; P | 2016 |
Anaesthesia for oncological surgery - can it really influence cancer recurrence?
Topics: Anesthesia; Apoptosis; Cell Proliferation; Colonic Neoplasms; Female; Humans; Male; Methyl Ethers; P | 2016 |
Anaesthesia for oncological surgery - can it really influence cancer recurrence?
Topics: Anesthesia; Apoptosis; Cell Proliferation; Colonic Neoplasms; Female; Humans; Male; Methyl Ethers; P | 2016 |
GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; Drug Screening Assays, Antitumor; GABA Agonist | 2010 |
GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; Drug Screening Assays, Antitumor; GABA Agonist | 2010 |
GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; Drug Screening Assays, Antitumor; GABA Agonist | 2010 |
GABA-receptor agonist, propofol inhibits invasion of colon carcinoma cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; Drug Screening Assays, Antitumor; GABA Agonist | 2010 |
Conscious or unconscious: the impact of sedation choice on colon adenoma detection.
Topics: Adenoma; Aged; Anesthesia; Choice Behavior; Colonic Neoplasms; Colonoscopy; Conscious Sedation; Fema | 2011 |
Glucuronidation as a mechanism of intrinsic drug resistance in human colon cancer: reversal of resistance by food additives.
Topics: Anthraquinones; Biopsy; Camptothecin; Catalysis; Cell Line, Tumor; Colonic Neoplasms; Drug Resistanc | 2003 |
Emergence from propofol anesthesia in a nonagenarian at a Bispectral Index of 52.
Topics: Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, Intravenous; | 2005 |
[Anesthesia in May-Hegglin anomaly].
Topics: Adenocarcinoma; Anesthesia, Intravenous; Anesthetics, Intravenous; Anticoagulants; Aprotinin; Bernar | 2006 |
Successful perioperative management of a patient with Parkinson's disease by enteral levodopa administration under propofol anesthesia.
Topics: Aged; Anesthetics, Intravenous; Anesthetics, Local; Antiparkinson Agents; Bupivacaine; Colonic Neopl | 1998 |