propofol has been researched along with Clostridium tetani Infection in 10 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Midazolam was administered as an antispastic therapy followed by human tetanus immune globulin and tetanus toxoid." | 7.73 | [Antispasm therapy using combination of midazolam and propofol for severe tetanus]. ( Hirano, T; Kamikawa, M; Kinoshita, Y; Uchino, M; Watanabe, M; Yonemitsu, K, 2005) |
| "A case of severe tetanus with autonomic dysfunction is reported, describing the adequate response to continuous infusions of both propofol and midazolam, and the successful use of clonidine to control sympathetic over-activity." | 7.68 | [Midazolam, propofol, and clonidine for sedation and control of autonomic dysfunction in severe generalized tetanus]. ( Peduto, VA; Piga, M; Pisanu, GM, 1993) |
| "We investigated the muscular relaxant properties of propofol in a 54 year-old-man with severe tetanus." | 7.68 | Sedation by propofol in tetanus--is it a muscular relaxant? ( Borgeat, A; Dessibourg, C; Rochani, M; Suter, PM, 1991) |
| "An adult patient with severe tetanus was successfully treated with alternating long-term infusions of propofol (20-80 mg/h, 8 + 3 days) and midazolam (5-15 mg/h, 29 days) for sedation, and with vecuronium infusion (6-8 mg/h, 35 days) for muscle relaxation." | 7.67 | Intravenous infusion of midazolam, propofol and vecuronium in a patient with severe tetanus. ( Himberg, JJ; Orko, R; Rosenberg, PH, 1988) |
| "Tetanus is an infectious disease caused by Clostridium tetani, which manifests systemic convulsion and autonomic instability associated with high case fatality." | 5.42 | Efficacy of concomitant use of dexmedetomidine and propofol in tetanus. ( Enomoto, Y; Hagiya, K; Kawano, S; Koyama, Y; Miya, K; Mizutani, T; Nishino, T; Shimojo, N; Yamasaki, Y, 2015) |
| "Tetanus is endemic in many developing countries." | 5.35 | The use of boluses of propofol for the management of severe tetanus in a child. ( Benois, A; Coulet, O; Eve, O; Petitjeans, F; Puidupin, M; Turc, J, 2009) |
| "Propofol was more effective than thiamylal to treat convulsion and to stabilize the sympathetic nerve activity." | 5.32 | [Propofol was useful for intractable convulsion in a patient with tetanus: a case report]. ( Akasaka, T; Amano, A; Jo, Y; Masuda, K; Ogata, S; Sato, T, 2003) |
| " Midazolam was administered as an antispastic therapy followed by human tetanus immune globulin and tetanus toxoid." | 3.73 | [Antispasm therapy using combination of midazolam and propofol for severe tetanus]. ( Hirano, T; Kamikawa, M; Kinoshita, Y; Uchino, M; Watanabe, M; Yonemitsu, K, 2005) |
| "A case of severe tetanus with autonomic dysfunction is reported, describing the adequate response to continuous infusions of both propofol and midazolam, and the successful use of clonidine to control sympathetic over-activity." | 3.68 | [Midazolam, propofol, and clonidine for sedation and control of autonomic dysfunction in severe generalized tetanus]. ( Peduto, VA; Piga, M; Pisanu, GM, 1993) |
| "We investigated the muscular relaxant properties of propofol in a 54 year-old-man with severe tetanus." | 3.68 | Sedation by propofol in tetanus--is it a muscular relaxant? ( Borgeat, A; Dessibourg, C; Rochani, M; Suter, PM, 1991) |
| "An adult patient with severe tetanus was successfully treated with alternating long-term infusions of propofol (20-80 mg/h, 8 + 3 days) and midazolam (5-15 mg/h, 29 days) for sedation, and with vecuronium infusion (6-8 mg/h, 35 days) for muscle relaxation." | 3.67 | Intravenous infusion of midazolam, propofol and vecuronium in a patient with severe tetanus. ( Himberg, JJ; Orko, R; Rosenberg, PH, 1988) |
| "Tetanus is an infectious disease caused by Clostridium tetani, which manifests systemic convulsion and autonomic instability associated with high case fatality." | 1.42 | Efficacy of concomitant use of dexmedetomidine and propofol in tetanus. ( Enomoto, Y; Hagiya, K; Kawano, S; Koyama, Y; Miya, K; Mizutani, T; Nishino, T; Shimojo, N; Yamasaki, Y, 2015) |
| "Tetanus is endemic in many developing countries." | 1.35 | The use of boluses of propofol for the management of severe tetanus in a child. ( Benois, A; Coulet, O; Eve, O; Petitjeans, F; Puidupin, M; Turc, J, 2009) |
| "Propofol was more effective than thiamylal to treat convulsion and to stabilize the sympathetic nerve activity." | 1.32 | [Propofol was useful for intractable convulsion in a patient with tetanus: a case report]. ( Akasaka, T; Amano, A; Jo, Y; Masuda, K; Ogata, S; Sato, T, 2003) |
| "A 75-year-old woman with breast cancer complicated with tetanus was scheduled for mastectomy." | 1.31 | [Anesthetic management of a patient with tetanus using epidural anesthesia]. ( Hamada, T; Higa, K; Kaneko, T; Katori, K; Nitahara, K; Shiratake, T, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perrin, L | 1 |
| Bisdorff, M | 1 |
| Saxena, S | 1 |
| Tabolcea, I | 1 |
| Huybrechts, I | 1 |
| Van Obbergh, L | 1 |
| Engelman, E | 1 |
| Barvais, L | 1 |
| Coeckelenbergh, S | 1 |
| Miya, K | 1 |
| Shimojo, N | 1 |
| Koyama, Y | 1 |
| Enomoto, Y | 1 |
| Hagiya, K | 1 |
| Yamasaki, Y | 1 |
| Nishino, T | 1 |
| Kawano, S | 1 |
| Mizutani, T | 1 |
| Petitjeans, F | 1 |
| Turc, J | 1 |
| Coulet, O | 1 |
| Puidupin, M | 1 |
| Eve, O | 1 |
| Benois, A | 1 |
| Sato, T | 1 |
| Masuda, K | 1 |
| Jo, Y | 1 |
| Akasaka, T | 1 |
| Amano, A | 1 |
| Ogata, S | 1 |
| Kamikawa, M | 1 |
| Watanabe, M | 1 |
| Hirano, T | 1 |
| Yonemitsu, K | 1 |
| Kinoshita, Y | 1 |
| Uchino, M | 1 |
| Peduto, VA | 1 |
| Pisanu, GM | 1 |
| Piga, M | 1 |
| Hamada, T | 1 |
| Katori, K | 1 |
| Nitahara, K | 1 |
| Shiratake, T | 1 |
| Kaneko, T | 1 |
| Higa, K | 1 |
| Borgeat, A | 2 |
| Dessibourg, C | 1 |
| Rochani, M | 1 |
| Suter, PM | 1 |
| Popovic, V | 1 |
| Schwander, D | 1 |
| Orko, R | 1 |
| Rosenberg, PH | 1 |
| Himberg, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluating the Predictive Value of the Nociception Level Index NOL: a Pilot Study[NCT03324269] | 36 participants (Actual) | Interventional | 2017-10-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 other studies available for propofol and Clostridium tetani Infection
| Article | Year |
|---|---|
Predicting personalised remifentanil effect site concentration for surgical incision using the nociception level index: A prospective calibration and validation study.
Topics: Calibration; Cohort Studies; Heart Rate; Humans; Nociception; Piperidines; Propofol; Prospective Stu | 2022 |
Efficacy of concomitant use of dexmedetomidine and propofol in tetanus.
Topics: Aged; Dexmedetomidine; Drug Therapy, Combination; Humans; Hypnotics and Sedatives; Male; Propofol; T | 2015 |
The use of boluses of propofol for the management of severe tetanus in a child.
Topics: Anesthetics, Intravenous; Anticonvulsants; Benzodiazepines; Child, Preschool; Humans; Male; Propofol | 2009 |
[Propofol was useful for intractable convulsion in a patient with tetanus: a case report].
Topics: Aged; Aged, 80 and over; Anticonvulsants; Female; Humans; Infusions, Intravenous; Propofol; Seizures | 2003 |
[Antispasm therapy using combination of midazolam and propofol for severe tetanus].
Topics: Aged; Drug Therapy, Combination; Female; Humans; Midazolam; Parasympatholytics; Propofol; Tetanus | 2005 |
[Midazolam, propofol, and clonidine for sedation and control of autonomic dysfunction in severe generalized tetanus].
Topics: Aged; Autonomic Nervous System; Clonidine; Conscious Sedation; Female; Humans; Midazolam; Propofol; | 1993 |
[Anesthetic management of a patient with tetanus using epidural anesthesia].
Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Breast Neoplasms; Female; Humans; Mastectomy; Propo | 2001 |
Sedation by propofol in tetanus--is it a muscular relaxant?
Topics: Electroencephalography; Humans; Injections, Intravenous; Male; Middle Aged; Propofol; Tetanus; Trism | 1991 |
Efficiency of a continuous infusion of propofol in a patient with tetanus.
Topics: Aged; Conscious Sedation; Female; Humans; Infusions, Intravenous; Propofol; Tetanus | 1991 |
Intravenous infusion of midazolam, propofol and vecuronium in a patient with severe tetanus.
Topics: Aged; Drug Administration Schedule; Humans; Infusions, Intravenous; Male; Midazolam; Phenols; Propof | 1988 |