propofol has been researched along with Cirrhosis, Liver in 38 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "BACKGROUND This prospective, randomized, controlled study evaluated the efficacy and safety of remimazolam tosilate sedation with adjuvant sufentanil, relative to propofol, for Chinese patients with liver cirrhosis undergoing gastroscopy." | 9.51 | Remimazolam Tosilate Sedation with Adjuvant Sufentanil in Chinese Patients with Liver Cirrhosis Undergoing Gastroscopy: A Randomized Controlled Study. ( Cao, Y; Chi, P; Lv, W; Quan, Z; Xue, FS; Zhou, C, 2022) |
| "Propofol-based sedation exacerbated MHE after EIS similarly to midazolam-based sedation in patients with liver cirrhosis." | 9.27 | Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial. ( Hashimoto, M; Hikichi, T; Irie, H; Kikuchi, H; Konno, N; Nakamura, J; Obara, K; Ohira, H; Sato, Y; Sugimoto, M; Suzuki, R; Takagi, T; Takasumi, M; Watanabe, K, 2018) |
| "Sedation with propofol has a shorter time recovery and a shorter time to discharge than midazolam and does not exacerbate sub-clinical hepatic encephalopathy in patients with compensated liver cirrhosis." | 9.15 | Sub-clinical hepatic encephalopathy in cirrhotic patients is not aggravated by sedation with propofol compared to midazolam: a randomized controlled study. ( Alex, I; Kamal, D; Khamaysi, I; Nimer, A; Olga, A; Vladimir, M; William, N, 2011) |
| "Midazolam sedation for upper gastrointestinal (GI) endoscopy exacerbates minimal hepatic encephalopathy (HE) in patients with liver cirrhosis, therefore an alternative drug regimen for these patients is warranted." | 9.14 | Propofol sedation for upper gastrointestinal endoscopy in patients with liver cirrhosis as an alternative to midazolam to avoid acute deterioration of minimal encephalopathy: a randomized, controlled study. ( Frenz, MB; Lechowicz, I; Riphaus, A; Wehrmann, T, 2009) |
| " Propofol (PRO) possesses a positive protective effect on liver ischemia reperfusion injury." | 8.31 | Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS. ( Liao, Q; Liao, Y; Liu, J; Luo, F; Luo, J; Mou, Y, 2023) |
| "The risk of hepatic encephalopathy (HE) precipitated by propofol has not been established." | 7.75 | Deep sedation with propofol does not precipitate hepatic encephalopathy during elective upper endoscopy. ( Amorós, A; Aparicio, JR; Casellas, JA; Garmendia, M; Jover, R; Martínez, J, 2009) |
| "BACKGROUND This prospective, randomized, controlled study evaluated the efficacy and safety of remimazolam tosilate sedation with adjuvant sufentanil, relative to propofol, for Chinese patients with liver cirrhosis undergoing gastroscopy." | 5.51 | Remimazolam Tosilate Sedation with Adjuvant Sufentanil in Chinese Patients with Liver Cirrhosis Undergoing Gastroscopy: A Randomized Controlled Study. ( Cao, Y; Chi, P; Lv, W; Quan, Z; Xue, FS; Zhou, C, 2022) |
| "He had liver cirrhosis caused by non- alcoholic steatohepatitis (NASH) with stage C of Child- Pugh classification." | 5.43 | [Desflurane Anesthesia and Intraoperative Motor Evoked Potential Monitoring of a Patient with Cervical Cavernous Hemangioma Complicated with Liver Cirrhosis]. ( Fukuda, S; Matayoshi, H; Miyake, N, 2016) |
| "Propofol-based sedation exacerbated MHE after EIS similarly to midazolam-based sedation in patients with liver cirrhosis." | 5.27 | Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial. ( Hashimoto, M; Hikichi, T; Irie, H; Kikuchi, H; Konno, N; Nakamura, J; Obara, K; Ohira, H; Sato, Y; Sugimoto, M; Suzuki, R; Takagi, T; Takasumi, M; Watanabe, K, 2018) |
| "Upper gastrointestinal endoscopy was performed under sedation with propofol along with careful monitoring in 20 patients with liver cirrhosis and 20 control subjects." | 5.19 | Is propofol safe when administered to cirrhotic patients during sedative endoscopy? ( Byun, KS; Choi, JH; Choung, RS; Hyun, JJ; Jung, SW; Kim, JH; Kim, KJ; Koo, JS; Lee, BJ; Lee, SW; Ryu, HS; Seo, YS; Suh, SJ; Um, SH; Yeon, JE; Yim, HJ; Yoon, EL, 2014) |
| "Safety of propofol sedation in patients with liver cirrhosis undergoing colonoscopy or endoscopic retrograde cholangiopancreatography (ERCP) remains to be studied." | 5.16 | Safety of propofol in cirrhotic patients undergoing colonoscopy and endoscopic retrograde cholangiography: results of a prospective controlled study. ( Barletti, C; Bruno, M; Carucci, P; Ceretto, S; Ciccone, G; De Angelis, C; De Cento, M; Fagà, E; Fagoonee, S; Giordanino, C; Musso, A; Pellicano, R; Reggio, D; Rizzetto, M; Saracco, G; Venon, WD, 2012) |
| "Sedation with propofol has a shorter time recovery and a shorter time to discharge than midazolam and does not exacerbate sub-clinical hepatic encephalopathy in patients with compensated liver cirrhosis." | 5.15 | Sub-clinical hepatic encephalopathy in cirrhotic patients is not aggravated by sedation with propofol compared to midazolam: a randomized controlled study. ( Alex, I; Kamal, D; Khamaysi, I; Nimer, A; Olga, A; Vladimir, M; William, N, 2011) |
| "Midazolam sedation for upper gastrointestinal (GI) endoscopy exacerbates minimal hepatic encephalopathy (HE) in patients with liver cirrhosis, therefore an alternative drug regimen for these patients is warranted." | 5.14 | Propofol sedation for upper gastrointestinal endoscopy in patients with liver cirrhosis as an alternative to midazolam to avoid acute deterioration of minimal encephalopathy: a randomized, controlled study. ( Frenz, MB; Lechowicz, I; Riphaus, A; Wehrmann, T, 2009) |
| " Propofol (PRO) possesses a positive protective effect on liver ischemia reperfusion injury." | 4.31 | Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS. ( Liao, Q; Liao, Y; Liu, J; Luo, F; Luo, J; Mou, Y, 2023) |
| "We aimed to investigate the safety of combined sedation with propofol plus fentanyl in patients with liver cirrhosis during screening esophagogastroduodenoscopy (SEGD) and a secondary prophylaxis for esophageal varices, endoscopic gastrointestinal ligation (EVL)." | 3.80 | The safety of combined sedation with propofol plus fentanyl for endoscopy screening and endoscopic variceal ligation in cirrhotic patients. ( Mao, W; Tao, J; Wei, XQ; Wen, ZF; Wu, B; Zhen, FP, 2014) |
| " Anesthetic technique consisted of either isoflurane or total intravenous anesthesia with propofol." | 3.76 | Right ventricular ejection fraction during orthotopic liver transplantation: does anesthetic technique make a difference? ( Auler, L; Diaz, R; Gouvêa, G; Martinho, JM; Toledo, R, 2010) |
| "The risk of hepatic encephalopathy (HE) precipitated by propofol has not been established." | 3.75 | Deep sedation with propofol does not precipitate hepatic encephalopathy during elective upper endoscopy. ( Amorós, A; Aparicio, JR; Casellas, JA; Garmendia, M; Jover, R; Martínez, J, 2009) |
| " However, no consensus has been reached whether sevoflurane could have adverse effects on renal function in cirrhotic patients." | 2.78 | Sevoflurane has no adverse effects on renal function in cirrhotic patients: a comparison with propofol. ( Lu, ZJ; Song, JC; Sun, YM; Wu, QC; Yang, LQ; Yu, WF; Zhang, MZ, 2013) |
| "Patients with liver cirrhosis frequently undergo diagnostic or therapeutic upper GI endoscopy (UGIE), and the liver disease might impair the metabolism of drugs usually administered for sedation." | 2.76 | Sedation during upper GI endoscopy in cirrhotic outpatients: a randomized, controlled trial comparing propofol and fentanyl with midazolam and fentanyl. ( Bonilha, DQ; Brito, JR; Correia, LM; Ferrari, AP; Gomes, GF; Lenz, L; Libera, ED; Nakao, FS; Rohr, MR, 2011) |
| "Sedation for upper gastrointestinal endoscopy (UGIE) in patients with cirrhosis is theoretically associated with high incidence of adverse events due to low levels of binding proteins and decreased hepatic clearance of drugs." | 1.62 | Safety of balanced propofol and midazolam in upper gastrointestinal endoscopy for sedation in cirrhotic patients. ( Alam, L; Alam, M; Khattak, MA, 2021) |
| "He had liver cirrhosis caused by non- alcoholic steatohepatitis (NASH) with stage C of Child- Pugh classification." | 1.43 | [Desflurane Anesthesia and Intraoperative Motor Evoked Potential Monitoring of a Patient with Cervical Cavernous Hemangioma Complicated with Liver Cirrhosis]. ( Fukuda, S; Matayoshi, H; Miyake, N, 2016) |
| "Shock was more common in patients with variceal bleeding compared to those with non-variceal bleeding (12." | 1.43 | Outcomes of Propofol Sedation During Emergency Endoscopy Performed for Upper Gastrointestinal Bleeding. ( Eun, CS; Han, DS; Jeon, YC; Jeong, JY; Park, CH; Sohn, JH; Yoo, KS, 2016) |
| " No adverse events occurred within 24 h after EGD." | 1.39 | Safety and effectiveness of low-dose propofol sedation during and after esophagogastroduodenoscopy in child A and B cirrhotic patients. ( Aoyama, T; Horiuchi, A; Isobe, M; Katsuyama, Y; Nakayama, Y; Ohmori, S; Tanaka, E; Tanaka, N, 2013) |
| "Hepatic encephalopathy is a neurologic syndrome secondary to liver failure that causes cognitive and motor abnormalities." | 1.33 | Functional abnormalities of the motor tract in the rat after portocaval anastomosis and after carbon tetrachloride induction of cirrhosis. ( Bartolí, R; Chatauret, N; Córdoba, J; Odena, G; Oria, M; Planas, R; Raguer, N, 2006) |
| "In the chronic renal failure group not undergoing regular hemodialysis (n = 9), unbound propofol was 0." | 1.29 | Serum protein binding of propofol in patients with renal failure or hepatic cirrhosis. ( Calvo, R; Carlos, R; Costela, JL; Jiménez, R; Suárez, E, 1996) |
| " Pharmacokinetic analysis was performed from the beginning of infusion to 8 h after termination." | 1.28 | Pharmacokinetics of propofol infusions in patients with cirrhosis. ( Cockshott, ID; Desmonts, JM; Farinotti, R; Haberer, JP; Servin, F; Winckler, C, 1990) |
| " The plasma concentration curve fits an open three compartment pharmacokinetic model, with distribution half-lives of 2." | 1.28 | [Pharmacokinetics of etomidate]. ( Assoune, P; Levron, JC, 1990) |
| "Propofol was extensively bound (mean: 97-98%) to the plasma protein of both cirrhotic and control groups." | 1.27 | Pharmacokinetics and protein binding of propofol in patients with cirrhosis. ( Cockshott, ID; Desmonts, JM; Farinotti, R; Haberer, JP; Plummer, GF; Servin, F, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (7.89) | 18.7374 |
| 1990's | 3 (7.89) | 18.2507 |
| 2000's | 5 (13.16) | 29.6817 |
| 2010's | 20 (52.63) | 24.3611 |
| 2020's | 7 (18.42) | 2.80 |
| Authors | Studies |
|---|---|
| Ebrahimi, F | 1 |
| Semela, D | 1 |
| Heim, M | 1 |
| Cao, Y | 1 |
| Chi, P | 1 |
| Zhou, C | 1 |
| Lv, W | 1 |
| Quan, Z | 1 |
| Xue, FS | 1 |
| Zhang, H | 1 |
| Yang, L | 1 |
| Yu, Z | 1 |
| Li, D | 1 |
| Li, L | 1 |
| Li, S | 1 |
| Yan, J | 1 |
| Li, X | 1 |
| Luo, J | 1 |
| Liu, J | 1 |
| Mou, Y | 1 |
| Luo, F | 1 |
| Liao, Q | 1 |
| Liao, Y | 1 |
| Ichijima, R | 1 |
| Yoo, JJ | 1 |
| Goong, HJ | 1 |
| Moon, JE | 1 |
| Kim, SG | 1 |
| Kim, YS | 1 |
| Jeong, J | 1 |
| Jung, K | 1 |
| Seo, KI | 1 |
| Yun, BC | 1 |
| Han, BH | 1 |
| Lee, SU | 1 |
| Moon, W | 1 |
| Alam, L | 1 |
| Khattak, MA | 1 |
| Alam, M | 1 |
| Watanabe, K | 1 |
| Hikichi, T | 1 |
| Takagi, T | 1 |
| Suzuki, R | 1 |
| Nakamura, J | 1 |
| Sugimoto, M | 1 |
| Kikuchi, H | 1 |
| Konno, N | 1 |
| Takasumi, M | 1 |
| Sato, Y | 1 |
| Hashimoto, M | 1 |
| Irie, H | 1 |
| Obara, K | 1 |
| Ohira, H | 1 |
| Matayoshi, H | 1 |
| Miyake, N | 1 |
| Fukuda, S | 1 |
| Song, JC | 2 |
| Zhang, MZ | 1 |
| Wu, QC | 1 |
| Lu, ZJ | 1 |
| Sun, YM | 1 |
| Yang, LQ | 2 |
| Yu, WF | 2 |
| Reverter, E | 1 |
| Blasi, A | 1 |
| Abraldes, JG | 1 |
| Martínez-Palli, G | 1 |
| Seijo, S | 1 |
| Turon, F | 1 |
| Berzigotti, A | 1 |
| Balust, J | 1 |
| Bosch, J | 1 |
| García-Pagán, JC | 1 |
| Wu, J | 1 |
| Zheng, SS | 1 |
| Mao, W | 1 |
| Wei, XQ | 1 |
| Tao, J | 1 |
| Zhen, FP | 1 |
| Wen, ZF | 1 |
| Wu, B | 1 |
| Sauerbruch, T | 1 |
| Suh, SJ | 1 |
| Yim, HJ | 1 |
| Yoon, EL | 1 |
| Lee, BJ | 1 |
| Hyun, JJ | 1 |
| Jung, SW | 1 |
| Koo, JS | 1 |
| Kim, JH | 1 |
| Kim, KJ | 1 |
| Choung, RS | 1 |
| Seo, YS | 1 |
| Yeon, JE | 1 |
| Um, SH | 1 |
| Byun, KS | 1 |
| Lee, SW | 1 |
| Choi, JH | 1 |
| Ryu, HS | 1 |
| Park, CH | 1 |
| Han, DS | 1 |
| Jeong, JY | 1 |
| Eun, CS | 1 |
| Yoo, KS | 1 |
| Jeon, YC | 1 |
| Sohn, JH | 1 |
| Amorós, A | 1 |
| Aparicio, JR | 1 |
| Garmendia, M | 1 |
| Casellas, JA | 1 |
| Martínez, J | 1 |
| Jover, R | 1 |
| Riphaus, A | 1 |
| Lechowicz, I | 1 |
| Frenz, MB | 1 |
| Wehrmann, T | 1 |
| Gouvêa, G | 1 |
| Diaz, R | 1 |
| Auler, L | 1 |
| Toledo, R | 1 |
| Martinho, JM | 1 |
| Lee, KH | 1 |
| Nam, SH | 1 |
| Yoo, SY | 1 |
| Jung, CW | 1 |
| Bae, SS | 1 |
| Lee, JR | 1 |
| Tao, KM | 1 |
| Liu, YT | 1 |
| Tao, Y | 1 |
| Wu, FX | 1 |
| Khamaysi, I | 1 |
| William, N | 1 |
| Olga, A | 1 |
| Alex, I | 1 |
| Vladimir, M | 1 |
| Kamal, D | 1 |
| Nimer, A | 1 |
| Sharma, P | 3 |
| Singh, S | 2 |
| Sharma, BC | 3 |
| Correia, LM | 1 |
| Bonilha, DQ | 1 |
| Gomes, GF | 1 |
| Brito, JR | 1 |
| Nakao, FS | 1 |
| Lenz, L | 1 |
| Rohr, MR | 1 |
| Ferrari, AP | 1 |
| Libera, ED | 1 |
| Kumar, M | 1 |
| Garg, H | 1 |
| Kumar, A | 1 |
| Sarin, SK | 2 |
| Fagà, E | 1 |
| De Cento, M | 1 |
| Giordanino, C | 1 |
| Barletti, C | 1 |
| Bruno, M | 1 |
| Carucci, P | 1 |
| De Angelis, C | 1 |
| Venon, WD | 1 |
| Musso, A | 1 |
| Reggio, D | 1 |
| Fagoonee, S | 1 |
| Pellicano, R | 1 |
| Ceretto, S | 1 |
| Ciccone, G | 1 |
| Rizzetto, M | 1 |
| Saracco, G | 1 |
| Agrawal, A | 1 |
| Uppal, R | 1 |
| Tanaka, N | 1 |
| Horiuchi, A | 1 |
| Nakayama, Y | 1 |
| Katsuyama, Y | 1 |
| Isobe, M | 1 |
| Aoyama, T | 1 |
| Tanaka, E | 1 |
| Ohmori, S | 1 |
| Gordon, G | 1 |
| Rastegar, H | 1 |
| Schumann, R | 1 |
| Deiss-Shrem, J | 1 |
| Denman, W | 1 |
| Weston, BR | 1 |
| Chadalawada, V | 1 |
| Chalasani, N | 1 |
| Kwo, P | 1 |
| Overley, CA | 1 |
| Symms, M | 1 |
| Strahl, E | 1 |
| Rex, DK | 1 |
| Oria, M | 1 |
| Raguer, N | 1 |
| Chatauret, N | 1 |
| Bartolí, R | 1 |
| Odena, G | 1 |
| Planas, R | 1 |
| Córdoba, J | 1 |
| Costela, JL | 1 |
| Jiménez, R | 1 |
| Calvo, R | 1 |
| Suárez, E | 1 |
| Carlos, R | 1 |
| Servin, F | 4 |
| Cockshott, ID | 2 |
| Farinotti, R | 4 |
| Haberer, JP | 4 |
| Winckler, C | 3 |
| Desmonts, JM | 4 |
| Levron, JC | 1 |
| Assoune, P | 1 |
| Plummer, GF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Fentanyl Analgesia on the Accuracy of Hepatic Venous Pressure Gradient Measurements in Patients With Portal Hypertension：a Prospective, Multicenter Study[NCT04724148] | 4 participants (Anticipated) | Interventional | 2022-01-01 | Recruiting | |||
| Intraoperative Evaluation of Right Ventricular Function During Liver Transplantation: a Quantitative Analysis Using Transesophageal Echocardiography[NCT03459924] | 19 participants (Actual) | Observational | 2018-02-27 | Active, not recruiting | |||
| Randomized Controlled Trial Comparing Effects of Sedation for Upper Gastrointestinal Endoscopy With Propofol Versus Midazolam on Psychometric Tests and Critical Flicker Frequency in Cirrhotics[NCT01356121] | Phase 4 | 120 participants (Anticipated) | Interventional | 2010-11-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 trials available for propofol and Cirrhosis, Liver
| Article | Year |
|---|---|
Remimazolam Tosilate Sedation with Adjuvant Sufentanil in Chinese Patients with Liver Cirrhosis Undergoing Gastroscopy: A Randomized Controlled Study.
Topics: Benzodiazepines; China; Gastroscopy; Humans; Hypnotics and Sedatives; Hypotension; Liver Cirrhosis; | 2022 |
Safety profile of sedative endoscopy including cognitive performance in liver cirrhosis: A double-blind randomized controlled trial.
Topics: Adult; Aged; Cognition; Double-Blind Method; Endoscopy, Gastrointestinal; Female; Humans; Hypnotics | 2019 |
Propofol is a more effective and safer sedative agent than midazolam in endoscopic injection sclerotherapy for esophageal varices in patients with liver cirrhosis: a randomized controlled trial.
Topics: Aged; Esophageal and Gastric Varices; Female; Hepatic Encephalopathy; Humans; Hypnotics and Sedative | 2018 |
Sevoflurane has no adverse effects on renal function in cirrhotic patients: a comparison with propofol.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Urea Nitrogen; Creatinine; Diuresis; | 2013 |
Is propofol safe when administered to cirrhotic patients during sedative endoscopy?
Topics: Adult; Endoscopy, Gastrointestinal; Female; Hepatic Encephalopathy; Humans; Hypnotics and Sedatives; | 2014 |
Propofol sedation for upper gastrointestinal endoscopy in patients with liver cirrhosis as an alternative to midazolam to avoid acute deterioration of minimal encephalopathy: a randomized, controlled study.
Topics: Aged; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; Hepatic Encephalopathy; H | 2009 |
Sub-clinical hepatic encephalopathy in cirrhotic patients is not aggravated by sedation with propofol compared to midazolam: a randomized controlled study.
Topics: Adult; Aged; Anesthesia Recovery Period; Cognition; Conscious Sedation; Endoscopy, Gastrointestinal; | 2011 |
Propofol in patients with cirrhosis and minimal hepatic encephalopathy.
Topics: Anesthetics, Intravenous; Endoscopy, Gastrointestinal; Hepatic Encephalopathy; Humans; Liver Cirrhos | 2011 |
Sedation during upper GI endoscopy in cirrhotic outpatients: a randomized, controlled trial comparing propofol and fentanyl with midazolam and fentanyl.
Topics: Analgesics, Opioid; Anesthesia Recovery Period; Bradycardia; Conscious Sedation; Deep Sedation; Endo | 2011 |
Propofol sedation during endoscopy in patients with cirrhosis, and utility of psychometric tests and critical flicker frequency in assessment of recovery from sedation.
Topics: Adult; Aged; Anesthesia Recovery Period; Cognition; Endoscopy, Gastrointestinal; Female; Flicker Fus | 2011 |
Safety of propofol in cirrhotic patients undergoing colonoscopy and endoscopic retrograde cholangiography: results of a prospective controlled study.
Topics: Adult; Aged; Anesthesia Recovery Period; Cholangiopancreatography, Endoscopic Retrograde; Colonoscop | 2012 |
Randomized controlled trial for endoscopy with propofol versus midazolam on psychometric tests and critical flicker frequency in people with cirrhosis.
Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Deep Sedation; Endoscopy, Gastrointestinal; | 2012 |
Nurse-administered propofol versus midazolam and meperidine for upper endoscopy in cirrhotic patients.
Topics: Aged; Ambulatory Care; Chronic Disease; Conscious Sedation; Dose-Response Relationship, Drug; Drug A | 2003 |
25 other studies available for propofol and Cirrhosis, Liver
| Article | Year |
|---|---|
Impact of propofol sedation on the diagnostic accuracy of hepatic venous pressure gradient measurements in patients with cirrhosis.
Topics: Cohort Studies; Fibrosis; Hepatic Veins; Humans; Hypertension, Portal; Liver Cirrhosis; Portal Press | 2022 |
Impact of fentanyl analgesia on the accuracy of HVPG measurements in patients with cirrhosis: a prospective, multicenter study.
Topics: Analgesia; Fentanyl; Humans; Liver Cirrhosis; Pain; Propofol; Prospective Studies | 2023 |
Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS.
Topics: Animals; Inflammation; Ischemia; Liver; Liver Cirrhosis; Mice; Propofol; Reperfusion; Reperfusion In | 2023 |
What is the best sedation method for high-risk patients such as those with cirrhosis?
Topics: Conscious Sedation; Humans; Hypnotics and Sedatives; Liver Cirrhosis; Propofol | 2023 |
Propofol alone prevents worsening hepatic encephalopathy rather than midazolam alone or combined sedation after esophagogastroduodenoscopy in compensated or decompensated cirrhotic patients.
Topics: Conscious Sedation; Endoscopy, Digestive System; Hepatic Encephalopathy; Humans; Hypnotics and Sedat | 2020 |
Safety of balanced propofol and midazolam in upper gastrointestinal endoscopy for sedation in cirrhotic patients.
Topics: Conscious Sedation; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedatives; Liver Cirrhosis; M | 2021 |
[Desflurane Anesthesia and Intraoperative Motor Evoked Potential Monitoring of a Patient with Cervical Cavernous Hemangioma Complicated with Liver Cirrhosis].
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Desflurane; Evoked Potential | 2016 |
Impact of deep sedation on the accuracy of hepatic and portal venous pressure measurements in patients with cirrhosis.
Topics: Adult; Aged; Anesthetics, Intravenous; Blood Pressure Determination; Deep Sedation; Female; Hepatic | 2014 |
Maintenance of unconsciousness with low plasma propofol concentrations in the neohepatic phase of liver transplantation using bispectral index-guided propofol anesthesia: a case report.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Consciousness Monitors; Hepatitis B, Chronic; Hum | 2013 |
The safety of combined sedation with propofol plus fentanyl for endoscopy screening and endoscopic variceal ligation in cirrhotic patients.
Topics: Adult; Conscious Sedation; Drug Combinations; Endoscopy, Digestive System; Endoscopy, Gastrointestin | 2014 |
Assessment of portal pressure in cirrhosis: how and when can we sedate?
Topics: Anesthetics, Intravenous; Blood Pressure Determination; Deep Sedation; Female; Hepatic Veins; Humans | 2014 |
Outcomes of Propofol Sedation During Emergency Endoscopy Performed for Upper Gastrointestinal Bleeding.
Topics: Adult; Age Factors; Aged; Anticoagulants; Cerebrovascular Disorders; Cohort Studies; Comorbidity; Di | 2016 |
Deep sedation with propofol does not precipitate hepatic encephalopathy during elective upper endoscopy.
Topics: Cohort Studies; Conscious Sedation; Elective Surgical Procedures; Endoscopy, Gastrointestinal; Femal | 2009 |
Right ventricular ejection fraction during orthotopic liver transplantation: does anesthetic technique make a difference?
Topics: Adult; Aged; Anesthesia; Anesthesia, Intravenous; Female; Hemodynamics; Humans; Isoflurane; Liver Ci | 2010 |
Vecuronium requirement during liver transplantation under sevoflurane anesthesia.
Topics: Aged; Analysis of Variance; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2010 |
Volatile anesthetics might be more beneficial than propofol for postoperative liver function in cirrhotic patients receiving hepatectomy.
Topics: Anesthetics, Inhalation; Desflurane; Heme Oxygenase (Decyclizing); Hepatectomy; Humans; Hypoxia-Indu | 2010 |
Safety and effectiveness of low-dose propofol sedation during and after esophagogastroduodenoscopy in child A and B cirrhotic patients.
Topics: Adult; Aged; Aged, 80 and over; Automobile Driving; Case-Control Studies; Endoscopy, Gastrointestina | 2013 |
Successful use of bivalirudin for cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia.
Topics: Anesthetics, Intravenous; Anticoagulants; Aortic Valve Insufficiency; Cardiopulmonary Bypass; Heart | 2003 |
Functional abnormalities of the motor tract in the rat after portocaval anastomosis and after carbon tetrachloride induction of cirrhosis.
Topics: Anastomosis, Surgical; Anesthetics, Intravenous; Animals; Carbon Tetrachloride; Disease Models, Anim | 2006 |
Serum protein binding of propofol in patients with renal failure or hepatic cirrhosis.
Topics: Adult; Anesthetics, Intravenous; Bilirubin; Blood Proteins; Chromatography, High Pressure Liquid; Cr | 1996 |
Pharmacokinetics of propofol infusions in patients with cirrhosis.
Topics: Adult; Anesthesia, Intravenous; Humans; Infusions, Intravenous; Liver; Liver Cirrhosis; Middle Aged; | 1990 |
[Pharmacokinetics of etomidate].
Topics: Adult; Age Factors; Aged; Etomidate; Humans; Liver Cirrhosis; Metabolic Clearance Rate; Methohexital | 1990 |
Pharmacokinetics of propofol administered by continuous infusion in patients with cirrhosis. Preliminary results.
Topics: Anesthesia, Intravenous; Anesthetics; Humans; Liver Cirrhosis; Middle Aged; Phenols; Propofol; Time | 1988 |
Pharmacokinetics and protein binding of propofol in patients with cirrhosis.
Topics: Adult; Anesthetics; Blood Proteins; Body Weight; Female; Half-Life; Humans; Liver; Liver Cirrhosis; | 1988 |
[Pharmacokinetics of the continuous infusion of propofol in the cirrhotic patient. Preliminary results].
Topics: Adult; Anesthetics; Humans; Infusions, Intravenous; Kinetics; Liver Cirrhosis; Middle Aged; Phenols; | 1987 |