Page last updated: 2024-11-03

propofol and Circulatory Collapse

propofol has been researched along with Circulatory Collapse in 23 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"This anesthetic drug may cause a rare condition named propofol infusion syndrome, characterized by unexplained lactic acidosis, lipemia, rhabdomyolysis, cardiovascular collapse and Brugada-like electrocardiographic pattern or Brugada electrocardiographic phenocopy changes following high-dose propofol infusion over prolonged periods of time."8.86Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy. ( Dubner, S; Ferreira, C; Filho, CF; Riera, AR; Schapachnik, E; Uchida, AH, 2010)
"Propofol infusion syndrome (PRIS) is well known, often associated with, lethal complication of sedation with propofol."7.78Propofol infusion syndrome heralded by ECG changes. ( Aslan, A; Jacobs, B; Mijzen, EJ; Rodgers, MG, 2012)
"Hypothesizing that propofol's pro and anticonvulsant effects might be dose dependent, we determined the effect of 25, 50, and 100% of a previously determined anesthetic dose of propofol for rats on the amount of lidocaine required to induce seizures."7.69Propofol prevents or elevates the threshold for lidocaine-induced seizures in rats. ( Cottrell, JE; Hartung, J; Weinberger, J; Ying, H, 1994)
"This anesthetic drug may cause a rare condition named propofol infusion syndrome, characterized by unexplained lactic acidosis, lipemia, rhabdomyolysis, cardiovascular collapse and Brugada-like electrocardiographic pattern or Brugada electrocardiographic phenocopy changes following high-dose propofol infusion over prolonged periods of time."4.86Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy. ( Dubner, S; Ferreira, C; Filho, CF; Riera, AR; Schapachnik, E; Uchida, AH, 2010)
"Propofol infusion syndrome (PRIS) is well known, often associated with, lethal complication of sedation with propofol."3.78Propofol infusion syndrome heralded by ECG changes. ( Aslan, A; Jacobs, B; Mijzen, EJ; Rodgers, MG, 2012)
"To investigate the characteristics and differences of propofol pharmacokinetics in shock phase and hypermetabolic phase in severe burn in rabbits."3.76[Pharmacokinetics differences of propofol during different pathological stages of severe burn in rabbits]. ( Chai, JK; Hao, JH; Hu, QG; Li, MM; Li, P; Liu, S; Sun, XF; Yang, HM, 2010)
"Although the plasma propofol concentration in the lactated Ringer's solution group increased with hemorrhage and infusion, it decreased in both the hydroxyethyl starch and the threefold lactated Ringer's solution groups."3.72Influence of fluid infusion associated with high-volume blood loss on plasma propofol concentrations. ( Fujii, S; Kazama, T; Kurita, T; Morita, K; Sato, S; Takata, K; Uraoka, M, 2004)
"Hypothesizing that propofol's pro and anticonvulsant effects might be dose dependent, we determined the effect of 25, 50, and 100% of a previously determined anesthetic dose of propofol for rats on the amount of lidocaine required to induce seizures."3.69Propofol prevents or elevates the threshold for lidocaine-induced seizures in rats. ( Cottrell, JE; Hartung, J; Weinberger, J; Ying, H, 1994)
"Patients suffering from critical illnesses like cardiac arrest with resuscitation and hypovolemic shock often are in need of medication."2.41[Pharmacology in critical illness]. ( Buylaert, WA, 2001)
"Propofol was commonly used and is potentially associated with poorer clinical outcomes."1.56Comparison of drugs used for intubation of pediatric trauma patients. ( Davidson, J; Merritt, N; Mudri, M; Priestap, F; Williams, A, 2020)
"Shock was more common in patients with variceal bleeding compared to those with non-variceal bleeding (12."1.43Outcomes of Propofol Sedation During Emergency Endoscopy Performed for Upper Gastrointestinal Bleeding. ( Eun, CS; Han, DS; Jeon, YC; Jeong, JY; Park, CH; Sohn, JH; Yoo, KS, 2016)
"This article describes a case of circulatory collapse in a young bodybuilder during anaesthesia."1.36[Circulatory collapse in bodybuilder during anaesthesia]. ( Afshari, A; Nielsen, JS; Ravn, T, 2010)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (34.78)18.2507
2000's5 (21.74)29.6817
2010's9 (39.13)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Mudri, M1
Williams, A1
Priestap, F1
Davidson, J1
Merritt, N1
Yu, T1
Huang, Y1
Guo, F1
Yang, Y1
Teboul, JL1
Qiu, H1
Park, CH1
Han, DS1
Jeong, JY1
Eun, CS1
Yoo, KS1
Jeon, YC1
Sohn, JH1
Au, AK1
Matthew Fields, J1
Mohammed, S1
Bhatia, PK1
Bhardwaj, P1
Kishore, K1
Kuric, V1
Zaza, KJ1
Algazlan, SS1
Hu, QG1
Hao, JH1
Chai, JK1
Yang, HM1
Sun, XF1
Li, P1
Li, MM1
Liu, S1
Riera, AR1
Uchida, AH1
Schapachnik, E1
Dubner, S1
Filho, CF1
Ferreira, C1
Ravn, T1
Afshari, A1
Nielsen, JS1
Mijzen, EJ1
Jacobs, B1
Aslan, A1
Rodgers, MG1
Kurita, T1
Kazama, T1
Morita, K1
Fujii, S1
Uraoka, M1
Takata, K1
Sato, S1
Kopka, A1
McMenemin, IM1
Serpell, MG1
Quasim, I1
Stekiel, TA1
Weber, CA1
Contney, SJ1
Bosnjak, ZJ1
Warden, JC1
Pickford, DR1
Bertin-Maghit, M1
Gueugniaud, PY1
Bouchard, C1
Petit, P1
Hartung, J1
Ying, H1
Weinberger, J1
Cottrell, JE1
Mackay, P1
Sneyd, JR1
Markovitz, BP1
Feuer, P1
Cox, P1
Buylaert, WA1
Ilkiw, JE1
Pascoe, PJ1
Haskins, SC1
Patz, JD1
Bellinzona, G1
Noli, S1
Maestri, M1
Spada, M1
Giordano, A1
Albertario, F1
Coven, G1
Mapelli, A1
Dandoy, M1
Poisson, F1
Reynaud, S1

Reviews

2 reviews available for propofol and Circulatory Collapse

ArticleYear
Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy.
    Cardiology journal, 2010, Volume: 17, Issue:2

    Topics: Acidosis, Lactic; Anesthetics, Intravenous; Animals; Brugada Syndrome; Electrocardiography; Heart Co

2010
[Pharmacology in critical illness].
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 2001, Volume: 63, Issue:5

    Topics: Adrenergic Agonists; Anesthetics, Intravenous; Animals; Calcium Channel Blockers; Cardiopulmonary Re

2001

Trials

1 trial available for propofol and Circulatory Collapse

ArticleYear
The effects of propofol and dexmedetomidine infusion onĀ fluid responsiveness in critically ill patients.
    The Journal of surgical research, 2013, Volume: 185, Issue:2

    Topics: Aged; Aged, 80 and over; Critical Illness; Dexmedetomidine; Female; Fluid Therapy; Hemodynamics; Hum

2013

Other Studies

20 other studies available for propofol and Circulatory Collapse

ArticleYear
Comparison of drugs used for intubation of pediatric trauma patients.
    Journal of pediatric surgery, 2020, Volume: 55, Issue:5

    Topics: Adolescent; Brain Injuries, Traumatic; Child; Child, Preschool; Etomidate; Female; Hospitals, Pediat

2020
Outcomes of Propofol Sedation During Emergency Endoscopy Performed for Upper Gastrointestinal Bleeding.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:3

    Topics: Adult; Age Factors; Aged; Anticoagulants; Cerebrovascular Disorders; Cohort Studies; Comorbidity; Di

2016
Ultrasound Measurement Of Inferior Vena Cava Collapse Predicts Propofol Induced Hypotension.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:3

    Topics: Humans; Hypotension; Hypotension, Controlled; Propofol; Shock; Vena Cava, Inferior

2017
Comments: Ultrasound measurement of inferior vena cava collapse predicts propofol-induced hypotension.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:3

    Topics: Humans; Hypotension, Controlled; Propofol; Shock; Ultrasonography; Vena Cava, Inferior

2017
Atypical presentation to rocuronium allergy in a 19-year-old female patient.
    Journal of clinical anesthesia, 2017, Volume: 37

    Topics: Adult; Anaphylaxis; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Cardiopulmonary Res

2017
[Pharmacokinetics differences of propofol during different pathological stages of severe burn in rabbits].
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2010, Volume: 26, Issue:1

    Topics: Animals; Burns; Propofol; Rabbits; Shock

2010
[Circulatory collapse in bodybuilder during anaesthesia].
    Ugeskrift for laeger, 2010, Jul-19, Volume: 172, Issue:29

    Topics: Adult; Anabolic Agents; Anesthesia, Intravenous; Anesthetics, Intravenous; Humans; Ileus; Male; Neur

2010
Propofol infusion syndrome heralded by ECG changes.
    Neurocritical care, 2012, Volume: 17, Issue:2

    Topics: Acidosis; Brain Injuries; Electrocardiography; Humans; Hypnotics and Sedatives; Intracranial Hyperte

2012
Influence of fluid infusion associated with high-volume blood loss on plasma propofol concentrations.
    Anesthesiology, 2004, Volume: 100, Issue:4

    Topics: Animals; Blood Volume; Cardiac Output; Fluid Therapy; Hemodilution; Hemorrhage; Propofol; Shock; Swi

2004
Anaesthesia for cholecystectomy in two non-parturients with Eisenmenger's syndrome.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:6

    Topics: Adult; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Cholecyst

2004
Differences in cardiovascular sensitivity to propofol in a chromosome substitution rat model.
    Croatian medical journal, 2007, Volume: 48, Issue:3

    Topics: Anesthetics, Intravenous; Animals; Animals, Congenic; Blood Pressure; Cardiovascular System; Chromos

2007
Fatal cardiovascular collapse following propofol induction in high-risk patients and dilemmas in the selection of a short-acting induction agent.
    Anaesthesia and intensive care, 1995, Volume: 23, Issue:4

    Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Cause of Death; Decision Making; Drug Administration

1995
[Problems caused by anesthesia of patients with severe burns].
    Cahiers d'anesthesiologie, 1995, Volume: 43, Issue:2

    Topics: Anesthesia, General; Anesthetics; Balneology; Burns; Debridement; Humans; Intraoperative Care; Ketam

1995
Propofol prevents or elevates the threshold for lidocaine-induced seizures in rats.
    Journal of neurosurgical anesthesiology, 1994, Volume: 6, Issue:4

    Topics: Animals; Anticonvulsants; Blood Pressure; Dose-Response Relationship, Drug; Electroencephalography;

1994
Fatal cardiovascular collapse following propofol induction in high-risk patients.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:1

    Topics: Aged; Cause of Death; Humans; Propofol; Risk Factors; Shock

1996
Catecholamine-resistant cardiovascular collapse after propofol, atracurium and gentamicin.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:5

    Topics: Adrenergic alpha-Agonists; Adult; Anesthetics, Intravenous; Anti-Bacterial Agents; Atracurium; Cardi

1998
Rare events often happen infrequently: propofol complications revisited.
    Critical care medicine, 2000, Volume: 28, Issue:6

    Topics: Acidosis; Anesthetics, Intravenous; Bradycardia; Child; Humans; Propofol; Rhabdomyolysis; Shock

2000
Cardiovascular and respiratory effects of propofol administration in hypovolemic dogs.
    American journal of veterinary research, 1992, Volume: 53, Issue:12

    Topics: Animals; Blood Pressure; Dog Diseases; Dogs; Female; Hemodynamics; Injections, Intravenous; Male; Pr

1992
[Propofol and acute hypovolemia. Experimental study].
    Minerva anestesiologica, 1991, Volume: 57, Issue:9

    Topics: Acute Disease; Animals; Hemodynamics; Propofol; Shock; Swine

1991
[Cardiovascular collapse following induction by propofol].
    Cahiers d'anesthesiologie, 1990, Volume: 38, Issue:5

    Topics: Anesthesia, Intravenous; Humans; Male; Middle Aged; Propofol; Shock

1990