Page last updated: 2024-11-03

propofol and Chronic Kidney Failure

propofol has been researched along with Chronic Kidney Failure in 24 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"The primary objective of this study was to compare the pharmacokinetics of dexmedetomidine in patients with end-stage renal failure and secondary hyperparathyroidism with those in normal individuals."7.88Pharmacokinetics of dexmedetomidine administered to patients with end-stage renal failure and secondary hyperparathyroidism undergoing general anaesthesia. ( Huang, XH; Li, R; Li, Y; Liu, QW; Zhang, MZ; Zhang, Y; Zhong, W, 2018)
"PRIS causing hyperkalemia is a well-known clinical entity."5.43Propofol Induced Hyperkalemia and Its Management in End Stage Renal Disease Patients. ( El-Ali, IM; Onuchic, A; Trivedi, RD; Virmani, S, 2016)
"The primary objective of this study was to compare the pharmacokinetics of dexmedetomidine in patients with end-stage renal failure and secondary hyperparathyroidism with those in normal individuals."3.88Pharmacokinetics of dexmedetomidine administered to patients with end-stage renal failure and secondary hyperparathyroidism undergoing general anaesthesia. ( Huang, XH; Li, R; Li, Y; Liu, QW; Zhang, MZ; Zhang, Y; Zhong, W, 2018)
"We aim to describe management of a patient receiving renal transplantation for chronic renal failure due to Alport syndrome with low dose of intrathecal bupivacaine and continuous epidural infusion of local anesthetic."3.83Low-dose Spinal Block With Continuous Epidural Infusion for Renal Transplantation in a Patient With Alport Syndrome: A Case Report. ( Brazzi, L; Bretto, P; Donadio, PP; Gobbi, F; Sales, G, 2016)
"Results: ESRD patients receiving propofol TCI had significantly less reduction in blood pressure than those receiving sevoflurane inhalation (p < 0."3.11Application of Propofol Target-Controlled Infusion for Optimized Hemodynamic Status in ESRD Patients Receiving Arteriovenous Access Surgery: A Randomized Controlled Trial. ( Chen, PC; Chen, PN; Huang, TW; Lin, WC; Lu, IC; Lu, WL; Tse, J, 2022)
"Among the 2576 cases in ESRD patients, 1374 were in the TIVA group and 1202 were in the volatile group."3.01The influence of propofol-based total intravenous anesthesia on postoperative outcomes in end-stage renal disease patients: A retrospective observation study. ( Cho, HB; Chung, JW; Jang, YS; Kim, MG; Kim, SH; Lee, HK; Park, S; Park, SY; Song, S; Yoo, JH, 2021)
"The Ce values of propofol at the time of loss of consciousness were 4."1.62Potency of propofol for inducing loss of consciousness in end-stage kidney disease patients. ( Cho, HB; Chung, JW; Han, KS; Jun, MR; Kim, MG; Kim, SH; Park, JE; Park, SY; Song, S; Yoo, JH, 2021)
"PRIS causing hyperkalemia is a well-known clinical entity."1.43Propofol Induced Hyperkalemia and Its Management in End Stage Renal Disease Patients. ( El-Ali, IM; Onuchic, A; Trivedi, RD; Virmani, S, 2016)
"Propofol was administrated with our TCI system at the target blood concentration of 4 microg x ml(-1) for three hours."1.35[Evaluation of target-controlled infusion for propofol in patients with chronic renal failure undergoing living-related renal transplantation]. ( Igarashi, T; Ikeda, M; Iwakiri, H; Nagata, O; Ozaki, M, 2009)
"Rocuronium 0."1.33Pharmacodynamics of rocuronium 0.3 mg kg(-1) in adult patients with and without renal failure. ( De Boer, H; Driessen, JJ; Robertson, EN; Scheffer, GJ; Vogt, M, 2005)
"Propofol was administered through the Diprifusor TCI system (Astra Zeneca) with the target concentration of propofol for induction set at 3 micrograms/mL for group A patients and 2."1.32[Predictive capability of the TCI Diprifusor system in patients with terminal chronic renal insufficiency]. ( Baxarias Gascón, P; Queraltó Companyo, JM; Sabaté Tenas, S; Soler Corbera, J, 2003)
"Propofol was administered at 0."1.31Evaluation of induction doses of propofol: comparison between endstage renal disease and normal renal function patients. ( Goyal, P; Pandey, CK; Puri, GD; Srivastva, S, 2002)
"Atracurium is administered to ten chronic renal failure patients in the course of kidney transplantation, abiding to all requirements and doses recommended by the company."1.30[The use of atracurium besylate (Tracrium) in patients undergoing kidney transplantation]. ( Bovianska, N, 1997)
"Propofol conjugates were determined after hydrolysis with beta glucuronidase or HCl."1.29Pharmacokinetics of propofol and its conjugates after continuous infusion in normal and in renal failure patients: a preliminary study. ( Benevent, D; Debord, J; Dupuis, JL; Feiss, P; Lachatre, G; Lagarde, M; Narcisse, F; Nathan, N, 1993)
"In the chronic renal failure group not undergoing regular hemodialysis (n = 9), unbound propofol was 0."1.29Serum protein binding of propofol in patients with renal failure or hepatic cirrhosis. ( Calvo, R; Carlos, R; Costela, JL; Jiménez, R; Suárez, E, 1996)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (29.17)18.2507
2000's9 (37.50)29.6817
2010's5 (20.83)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Chen, PN1
Lu, IC1
Huang, TW1
Chen, PC1
Lin, WC1
Lu, WL1
Tse, J1
Cho, HB2
Kim, MG2
Park, SY2
Song, S2
Jang, YS1
Park, S1
Lee, HK1
Yoo, JH2
Chung, JW2
Kim, SH2
Jun, MR1
Han, KS1
Park, JE1
Zhong, W1
Zhang, Y1
Zhang, MZ1
Huang, XH1
Li, Y1
Li, R1
Liu, QW1
Virmani, S1
Onuchic, A1
El-Ali, IM1
Trivedi, RD1
Kumar, G1
Gobbi, F1
Sales, G1
Bretto, P1
Donadio, PP1
Brazzi, L1
Kocabas, S1
Yedicocuklu, D1
Askar, FZ1
Igarashi, T1
Nagata, O1
Iwakiri, H1
Ikeda, M1
Ozaki, M1
Goyal, P1
Puri, GD1
Pandey, CK1
Srivastva, S1
Sabaté Tenas, S1
Soler Corbera, J1
Queraltó Companyo, JM1
Baxarias Gascón, P1
Kakinohana, M1
Tokumine, J1
Kawashima, S1
Koja, H1
Sugahara, K1
Tatebayashi, S1
Imai, Y1
Ohgi, K1
Tamaki, S1
Yamamoto, K1
Takahashi, M1
Kurehara, K1
Furuya, H1
Kirita, T1
Robertson, EN1
Driessen, JJ1
Vogt, M1
De Boer, H1
Scheffer, GJ1
Wang, YC1
Liu, BM1
Supernaw, RB1
Lu, YH1
Lee, PY1
Honda, A1
Arai, T1
Akiyama, M1
Masuda, E1
Kobayashi, M1
Hoka, S1
Lee, SM1
Kim, GH1
Lee, JJ1
Kim, JA1
Choi, SJ1
Kim, GS1
Jung, HH1
Nathan, N1
Debord, J1
Narcisse, F1
Dupuis, JL1
Lagarde, M1
Benevent, D1
Lachatre, G1
Feiss, P1
Costela, JL1
Jiménez, R1
Calvo, R1
Suárez, E1
Carlos, R1
Bovianska, N1
Kurokawa, S1
Taga, K1
Tobita, T1
Kitahara, Y1
Fukuda, S1
Shimoji, K1
Ickx, B1
Cockshott, ID1
Barvais, L1
Byttebier, G1
De Pauw, L1
Vandesteene, A1
D'Hollander, AA1
Dahaba, AA1
von Klobucar, F1
Rehak, PH1
List, WF1
Yamauchi, M1
Igarashi, M1
Tsunoda, K1
Edanaga, M1
Suzuki, H1
Tohdoh, Y1
Namiki, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Comparative Study of Sevoflurane Sedation With TCI Propofol Sedation in Dialysis Dependent End Stage Renal Failure Patients for Transposition of Brachiocephalic Fistula Repair[NCT04839536]Phase 436 participants (Anticipated)Interventional2021-04-01Not yet recruiting
Evaluation of Duration of Curarisation (Surgical Efficacy) and Pharmacokinetics of Neuromuscular Block After a Single Dose of Rocuronium in Geriatric Patients (Age ≥ 80 Years ) Compared to a Younger Population (Age < 50 Years).[NCT03551652]28 participants (Anticipated)Observational2020-05-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for propofol and Chronic Kidney Failure

ArticleYear
Application of Propofol Target-Controlled Infusion for Optimized Hemodynamic Status in ESRD Patients Receiving Arteriovenous Access Surgery: A Randomized Controlled Trial.
    Medicina (Kaunas, Lithuania), 2022, Sep-01, Volume: 58, Issue:9

    Topics: Anesthesia, Inhalation; Anesthetics, Intravenous; Hemodynamics; Humans; Kidney Failure, Chronic; Pai

2022
The influence of propofol-based total intravenous anesthesia on postoperative outcomes in end-stage renal disease patients: A retrospective observation study.
    PloS one, 2021, Volume: 16, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Female; Heart Diseases; Humans; Incidence;

2021
Propofol infusion for induction and maintenance of anaesthesia in patients with end-stage renal disease.
    British journal of anaesthesia, 1998, Volume: 81, Issue:6

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Consciousness;

1998
[Cardiovascular responses during laryngeal mask airway insertion in normotensive, hypertensive and chronic renal failure patients].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48, Issue:8

    Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Hemodynamics; Humans; Hypertension;

1999

Other Studies

20 other studies available for propofol and Chronic Kidney Failure

ArticleYear
Potency of propofol for inducing loss of consciousness in end-stage kidney disease patients.
    PloS one, 2021, Volume: 16, Issue:8

    Topics: Aged; Anesthesia, Epidural; Anesthesia, Intravenous; Anesthetics, Intravenous; Consciousness; Dose-R

2021
Pharmacokinetics of dexmedetomidine administered to patients with end-stage renal failure and secondary hyperparathyroidism undergoing general anaesthesia.
    Journal of clinical pharmacy and therapeutics, 2018, Volume: 43, Issue:3

    Topics: Adult; Anesthesia, General; Case-Control Studies; Dexmedetomidine; Female; Half-Life; Humans; Hyperp

2018
Propofol Induced Hyperkalemia and Its Management in End Stage Renal Disease Patients.
    Connecticut medicine, 2016, Volume: 80, Issue:8

    Topics: Anesthetics, Intravenous; Arrhythmias, Cardiac; Electrocardiography; Heart Arrest; Humans; Hyperkale

2016
Propofol as a Cause of Recurrent Pancreatitis in A Child with ESRD; A Cautionary Tale.
    Indian journal of pediatrics, 2019, Volume: 86, Issue:4

    Topics: Anesthetics, Intravenous; Child; Female; Humans; Kidney Failure, Chronic; Pancreatitis; Propofol; Re

2019
Low-dose Spinal Block With Continuous Epidural Infusion for Renal Transplantation in a Patient With Alport Syndrome: A Case Report.
    Transplantation proceedings, 2016, Volume: 48, Issue:9

    Topics: Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Anestheti

2016
The neuromuscular effects of 0.6 mg kg(-1) rocuronium in elderly and young adults with or without renal failure.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Androstanols; Anesthetics, Intravenous; Female; Humans;

2008
[Evaluation of target-controlled infusion for propofol in patients with chronic renal failure undergoing living-related renal transplantation].
    Masui. The Japanese journal of anesthesiology, 2009, Volume: 58, Issue:9

    Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Female; Humans; Infusions, Intravenous; Kidney

2009
Evaluation of induction doses of propofol: comparison between endstage renal disease and normal renal function patients.
    Anaesthesia and intensive care, 2002, Volume: 30, Issue:5

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Case-Control S

2002
[Predictive capability of the TCI Diprifusor system in patients with terminal chronic renal insufficiency].
    Revista espanola de anestesiologia y reanimacion, 2003, Volume: 50, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Dose-Response Relationship, Dr

2003
Patient-controlled sedation using propofol in eight patients with endstage renal failure.
    Journal of anesthesia, 2004, Volume: 18, Issue:1

    Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Conscious Sedation; Female; Hemodynamics; Humans; Hypnot

2004
[The influence of intermittent hemodialysis (HD) on bispectral index (scale) (BIS) and serum propofol concentration under postoperative intravenous sedation].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:5

    Topics: Anesthesia, General; Anesthetics, Intravenous; Gingival Neoplasms; Heart Rate; Humans; Hypnotics and

2004
Pharmacodynamics of rocuronium 0.3 mg kg(-1) in adult patients with and without renal failure.
    European journal of anaesthesiology, 2005, Volume: 22, Issue:12

    Topics: Adult; Androstanols; Anesthesia, Intravenous; Anesthetics, Intravenous; Female; Humans; Intubation,

2005
Management of star fruit-induced neurotoxicity and seizures in a patient with chronic renal failure.
    Pharmacotherapy, 2006, Volume: 26, Issue:1

    Topics: Aged, 80 and over; Anesthetics, Intravenous; Anticonvulsants; Coma; Fatal Outcome; Female; Fruit; Hu

2006
Anesthetic management of a patient with a history of Batista procedure for dilated cardiomyopathy undergoing gastric surgery.
    Journal of anesthesia, 2006, Volume: 20, Issue:3

    Topics: Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine

2006
Does propofol and alfentanil-induced sedation cause periodic apnoea in chronic renal failure patients?
    International journal of clinical practice, 2010, Volume: 64, Issue:1

    Topics: Alfentanil; Anesthetics, Combined; Anesthetics, Intravenous; Apnea; Case-Control Studies; Female; Hu

2010
Pharmacokinetics of propofol and its conjugates after continuous infusion in normal and in renal failure patients: a preliminary study.
    Acta anaesthesiologica Belgica, 1993, Volume: 44, Issue:3

    Topics: Adult; Aged; Chromatography, High Pressure Liquid; Female; Glucuronidase; Half-Life; Humans; Hydroly

1993
Serum protein binding of propofol in patients with renal failure or hepatic cirrhosis.
    Acta anaesthesiologica Scandinavica, 1996, Volume: 40, Issue:6

    Topics: Adult; Anesthetics, Intravenous; Bilirubin; Blood Proteins; Chromatography, High Pressure Liquid; Cr

1996
[The use of atracurium besylate (Tracrium) in patients undergoing kidney transplantation].
    Khirurgiia, 1997, Volume: 50, Issue:1

    Topics: Anesthetics, Intravenous; Atracurium; Humans; Kidney Failure, Chronic; Kidney Transplantation; Neuro

1997
[Anesthetic management for pericardial fenestration in a hypertrophic cardiomyopathy (HCM) patient with massive pericardial effusion].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48, Issue:2

    Topics: Aged; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Atrial Fibrillation;

1999
Total intravenous anesthesia with remifentanil, propofol and cisatracurium in end-stage renal failure.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:7

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Atracurium; Female; Hemodynamics; Humans;

1999