propofol has been researched along with Cerebral Palsy in 16 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We designed a randomized prospective study to investigate whether developmentally delayed children with cerebral palsy (CP) need a lower dosage of propofol for induction than normal children using bispectral index (BIS) monitoring criteria." | 9.11 | The evaluation of propofol dosage for anesthesia induction in children with cerebral palsy with bispectral index (BIS) monitoring. ( Aypar, U; Celebi, N; Celik, M; Saricaoglu, F, 2005) |
| "To investigate the safety and efficacy of a propofol and ketamine based sedation protocol in pediatric patients with cerebral palsy requiring BoNT-A injections." | 7.91 | Safety and Efficacy of a Propofol and Ketamine Based Procedural Sedation Protocol in Children with Cerebral Palsy Undergoing Botulinum Toxin A Injections. ( Abu-Sultaneh, S; Abulebda, K; Louer, R; Lutfi, R; McKinney, RC, 2019) |
| "Propofol is a sedative and a hypnotic agent used in the induction and maintenance of general anesthesia." | 5.56 | Spastic Cerebral Palsy Pain Improvement With Propofol: A Case Report. ( Guichard, L; Lansaman, T; Martinez, V, 2020) |
| "We designed a randomized prospective study to investigate whether developmentally delayed children with cerebral palsy (CP) need a lower dosage of propofol for induction than normal children using bispectral index (BIS) monitoring criteria." | 5.11 | The evaluation of propofol dosage for anesthesia induction in children with cerebral palsy with bispectral index (BIS) monitoring. ( Aypar, U; Celebi, N; Celik, M; Saricaoglu, F, 2005) |
| "To investigate the safety and efficacy of a propofol and ketamine based sedation protocol in pediatric patients with cerebral palsy requiring BoNT-A injections." | 3.91 | Safety and Efficacy of a Propofol and Ketamine Based Procedural Sedation Protocol in Children with Cerebral Palsy Undergoing Botulinum Toxin A Injections. ( Abu-Sultaneh, S; Abulebda, K; Louer, R; Lutfi, R; McKinney, RC, 2019) |
| "We investigated the impact of the type of neurological disorder on the required propofol dose for anesthesia and the time to emerge from anesthesia during dental treatment in patients with autism (AU), cerebral palsy (CP), and intellectual disability (ID), some of whom also had epilepsy." | 3.81 | Required propofol dose for anesthesia and time to emerge are affected by the use of antiepileptics: prospective cohort study. ( Ouchi, K; Sugiyama, K, 2015) |
| " A significant odds ratio related to decreased SpO2 was observed for age, sex, midazolam and propofol levels, concurrent use of nitrous oxide, cerebral palsy, Down syndrome, and mental retardation." | 3.79 | Risk factors with intravenous sedation for patients with disabilities. ( Fukayama, H; Ishikawa, M; Jinno, S; Kohase, H; Kunimori, H; Miwa, Z; Nakamura, Z; Okumura, H; Shimoyama, K; Tamaki, Y; Yoshikawa, F, 2013) |
| "Following a propofol anesthetic, a 5-year-old girl with lower extremity spasticity seized and developed hypertriglyceridemia, hyperkalemia, and metabolic acidosis." | 3.79 | Propofol infusion syndrome or adrenoleukodystrophy? ( Agin, H; Goktay, A; Karaarslan, U; Karaman, Y, 2013) |
| "In 6 patients with Parkinson's disease and 1 with cerebral palsy, muscle afferent-evoked thalamic potentials (METPs) were recorded in the ventral intermediate (Vim) nucleus." | 2.69 | Thalamic potentials evoked by motor point stimulation. ( Fukuda, M; Kameyama, S; Tanaka, R, 2000) |
| "There was no recurrence of muscle hypertonia, and she recovered fully without complications." | 1.91 | Positional Change Used to Manage Postextubation Respiratory Failure in a Child With Cerebral Palsy. ( Hidaka, K; Hirokawa, J; Hitosugi, T; Kanemaru, M; Oshima, Y; Yokoyama, T, 2023) |
| "Propofol is a sedative and a hypnotic agent used in the induction and maintenance of general anesthesia." | 1.56 | Spastic Cerebral Palsy Pain Improvement With Propofol: A Case Report. ( Guichard, L; Lansaman, T; Martinez, V, 2020) |
| "Propofol was titrated to increase the level of sedation with a continuous infusion of remifentanil at a rate of 0." | 1.51 | Validity of bispectral index monitoring during deep sedation in children with spastic cerebral palsy undergoing injection of botulinum toxin. ( Jung, SM; Lee, E; Park, SJ, 2019) |
| "Midazolam was used in approximately 47% in the MC group." | 1.40 | Survey on choice of intravenous sedative agent at department of dental anesthesiology, Tokyo Dental College Chiba Hospital between 2010 and 2011. ( Ichinohe, T; Kasahara, M; Matsuki, Y; Matsuura, N; Okamura, T; Shiozaki, K, 2014) |
| "In 28 patients with Parkinson's disease including seven juvenile cases of parkinsonism, the postoperative motor and ADL scores on the Unified Parkinson's Disease Rating Scale significantly improved." | 1.30 | [Stereotaxy during intravenous anesthesia with propofol]. ( Fukuda, M; Kameyama, S; Kawaguchi, T; Tanaka, R; Yamashita, S, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Hirokawa, J | 1 |
| Hidaka, K | 1 |
| Kanemaru, M | 1 |
| Hitosugi, T | 1 |
| Oshima, Y | 1 |
| Yokoyama, T | 1 |
| Martinez, V | 1 |
| Lansaman, T | 1 |
| Guichard, L | 1 |
| Louer, R | 1 |
| McKinney, RC | 1 |
| Abu-Sultaneh, S | 1 |
| Lutfi, R | 1 |
| Abulebda, K | 1 |
| Jung, SM | 1 |
| Lee, E | 1 |
| Park, SJ | 1 |
| Yoshikawa, F | 1 |
| Tamaki, Y | 1 |
| Okumura, H | 1 |
| Miwa, Z | 1 |
| Ishikawa, M | 1 |
| Shimoyama, K | 1 |
| Nakamura, Z | 1 |
| Kunimori, H | 1 |
| Jinno, S | 1 |
| Kohase, H | 1 |
| Fukayama, H | 1 |
| Matsuki, Y | 1 |
| Okamura, T | 1 |
| Shiozaki, K | 1 |
| Matsuura, N | 1 |
| Kasahara, M | 1 |
| Ichinohe, T | 1 |
| Ouchi, K | 1 |
| Sugiyama, K | 1 |
| Matsunami, S | 1 |
| Komasawa, N | 1 |
| Fujiwara, S | 1 |
| Fujitate, Y | 1 |
| Soen, M | 1 |
| Minami, T | 1 |
| Karaman, Y | 1 |
| Goktay, A | 1 |
| Agin, H | 1 |
| Karaarslan, U | 1 |
| Loyola-Rodriguez, JP | 1 |
| Aguilera-Morelos, AA | 1 |
| Santos-Diaz, MA | 1 |
| Zavala-Alonso, V | 1 |
| Davila-Perez, C | 1 |
| Olvera-Delgado, H | 1 |
| Patiño-Marin, N | 1 |
| De Leon-Cobian, I | 1 |
| Saricaoglu, F | 1 |
| Celebi, N | 1 |
| Celik, M | 1 |
| Aypar, U | 1 |
| Theroux, MC | 1 |
| Brandom, BW | 1 |
| Zagnoev, M | 1 |
| Kettrick, RG | 1 |
| Miller, F | 1 |
| Ponce, C | 1 |
| Fukuda, M | 2 |
| Kameyama, S | 2 |
| Kawaguchi, T | 1 |
| Yamashita, S | 1 |
| Tanaka, R | 2 |
| Kariya, N | 1 |
| Toyoyama, H | 1 |
| Furuichi, K | 1 |
| Kubota, H | 1 |
| Toyoda, Y | 1 |
| Baso, R | 1 |
| Valenti, S | 1 |
| Alberti, A | 1 |
| Gallo, F | 1 |
| Favaretto, E | 1 |
| Novello, A | 1 |
| Vincenti, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Bispectral Index Monitoring on the Speed of Recovery From Deep Propofol Sedation in Children With Cerebral Palsy - A Randomized Controlled Trial[NCT04190082] | 12 participants (Actual) | Observational | 2021-05-01 | Terminated (stopped due to No more participants enrolled.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for propofol and Cerebral Palsy
| Article | Year |
|---|---|
The evaluation of propofol dosage for anesthesia induction in children with cerebral palsy with bispectral index (BIS) monitoring.
Topics: Anesthesia, General; Anesthetics, Intravenous; Cerebral Palsy; Child; Communication Disorders; Devel | 2005 |
Dose response of succinylcholine at the adductor pollicis of children with cerebral palsy during propofol and nitrous oxide anesthesia.
Topics: Anesthesia, General; Cerebral Palsy; Child; Child, Preschool; Cholinesterases; Dose-Response Relatio | 1994 |
Thalamic potentials evoked by motor point stimulation.
Topics: Aged; Anesthetics, Intravenous; Cerebral Palsy; Electric Stimulation; Evoked Potentials; Female; Hum | 2000 |
13 other studies available for propofol and Cerebral Palsy
| Article | Year |
|---|---|
Positional Change Used to Manage Postextubation Respiratory Failure in a Child With Cerebral Palsy.
Topics: Adolescent; Cerebral Palsy; Child; Female; Humans; Muscle Hypertonia; Muscle Spasticity; Propofol; R | 2023 |
Spastic Cerebral Palsy Pain Improvement With Propofol: A Case Report.
Topics: Adult; Analgesics; Anesthetics, Intravenous; Cerebral Palsy; Humans; Hypnotics and Sedatives; Male; | 2020 |
Safety and Efficacy of a Propofol and Ketamine Based Procedural Sedation Protocol in Children with Cerebral Palsy Undergoing Botulinum Toxin A Injections.
Topics: Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, Preschool; Conscious Sedation; Female; Hospi | 2019 |
Validity of bispectral index monitoring during deep sedation in children with spastic cerebral palsy undergoing injection of botulinum toxin.
Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, Preschool; Consciousness Monitor | 2019 |
Risk factors with intravenous sedation for patients with disabilities.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Dental; Anesthes | 2013 |
Survey on choice of intravenous sedative agent at department of dental anesthesiology, Tokyo Dental College Chiba Hospital between 2010 and 2011.
Topics: Administration, Intravenous; Adult; Aged; Anesthesia, Dental; Anesthetics, Intravenous; Cerebral Pal | 2014 |
Required propofol dose for anesthesia and time to emerge are affected by the use of antiepileptics: prospective cohort study.
Topics: Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Anticonvulsants; Autistic Disorder; Cer | 2015 |
[Anesthetic Management Using Frontal Nerve, Greater Occipital Nerve, and Superficial Cervical Plexus Block for Posterior Cervical Spinal Fusion in a Patient with Athetoid Cerebral Palsy].
Topics: Aged; Amides; Cerebral Palsy; Cervical Plexus; Cervical Plexus Block; Cervical Vertebrae; Cranial Ne | 2015 |
Propofol infusion syndrome or adrenoleukodystrophy?
Topics: Acidosis; Anesthetics, Intravenous; Blood Gas Analysis; Cerebral Palsy; Child, Preschool; Female; Hu | 2013 |
Oral rehabilitation under dental general anesthesia, conscious sedation, and conventional techniques in patients affected by cerebral palsy.
Topics: Adolescent; Adolescent Behavior; Adult; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, | 2004 |
[Stereotaxy during intravenous anesthesia with propofol].
Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Brain; Cerebral Palsy; Female; Human | 1998 |
Induction of general anesthesia using propofol for cesarean section of a woman with cerebral palsy.
Topics: Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Intravenous; Cerebral Palsy; Cesarean Sec | 1999 |
[Anesthesia with propofol in continuous infusion in patients with infantile cerebral paralysis undergoing orthopedic surgery].
Topics: Adolescent; Anesthesia, Intravenous; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Infusi | 1991 |