Page last updated: 2024-11-03

propofol and Cardiovascular Stroke

propofol has been researched along with Cardiovascular Stroke in 39 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"The aim of the present study was to investigate the protective effect of propofol on the experimental myocardial infarction in rats."8.02[The myocardial protective effect of propofol on rats with experimental myocardial infarction and its mechanism]. ( Liu, JL; Tian, QX; Zhang, MX, 2021)
"To investigate the effects of propofol, midazolam and thiopental sodium on outcomes and amino acid accumulation in focal cerebral ischemia-reperfusion in rats."7.72Effects of propofol, midazolam and thiopental sodium on outcome and amino acids accumulation in focal cerebral ischemia-reperfusion in rats. ( Chen, L; Gong, Q; Xiao, C, 2003)
"In a randomized, single-blinded, placebo-controlled prospective study, serum troponin I concentration (cTnI) (baseline, and 1, 6, 12, 24, 48, and 72 h postoperatively) were measured during isoflurane/sufentanil or propofol/sufentanil anesthesia with or without RIPC (three 5-min periods of intermittent left upper arm ischemia with 5 min reperfusion each) in non-diabetic patients (n = 72) with three-vessel coronary artery disease (ClinicalTrials."5.16Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trial. ( Bergmann, L; Heine, T; Heusch, G; Jakob, H; Kottenberg, E; Peters, J; Thielmann, M, 2012)
" There was no difference in the incidence of breakthrough hypertension between the two groups (in 44% and 43% of the patients, respectively) and in the number of alfentanil bolus supplements."5.08Continuous infusions of alfentanil and propofol for coronary artery surgery. ( de Lange, S; Gerrits, HJ; Roekaerts, PM; Timmerman, BE, 1995)
" Cardiac morbidity (postoperative myocardial ischemia, postoperative myocardial infarction, and perioperative sympathoadrenal stress response), respiratory morbidity (postextubation apnea, alveolar-arterial oxygen gradient, pulmonary shunting, oxygen consumption, atelectasis, and reintubation), hemodynamic values and vasoactive medication requirements, intraoperative awareness, postoperative cognitive function, 30 day mortality, and intensive care unit and hospital lengths of stay were compared between the two groups."5.08Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial. ( Asokumar, B; Carroll, J; Cheng, DC; David, T; Karski, J; Mickle, D; Nierenberg, H; Peniston, C; Raveendran, G; Roger, S; Sandler, A; Tong, J; Zelovitsky, J, 1996)
" Thirty-day complication rates were compared with EGD under sedation or not, type of sedation drugs (midazolam only vs midazolam/propofol) and age groups (18-64 year vs ≥65 year) for GI (bleeding and perforation) and non-GI complications (pneumonia, acute myocardial infarction, congestive heart failure and cerebral stroke)."4.12Gastrointestinal and non-gastrointestinal complication rates associated with diagnostic esophagogastroduodenoscopy under sedation. ( Cha, JM; Jang, JM; Kwak, MS; Park, SB; Yoon, JY, 2022)
"The aim of the present study was to investigate the protective effect of propofol on the experimental myocardial infarction in rats."4.02[The myocardial protective effect of propofol on rats with experimental myocardial infarction and its mechanism]. ( Liu, JL; Tian, QX; Zhang, MX, 2021)
" Propofol was given to patients reporting pain or discomfort throughout the procedure."3.81Incidence of and indications for conversion of cervical plexus block to general anesthesia in patients undergoing carotid surgery: a single center experience. ( Davidovic, LB; Koncar, I; Kostic, D; Lucic, M; Sindjelic, RP; Vlajkovic, GP, 2015)
"To investigate the effects of propofol, midazolam and thiopental sodium on outcomes and amino acid accumulation in focal cerebral ischemia-reperfusion in rats."3.72Effects of propofol, midazolam and thiopental sodium on outcome and amino acids accumulation in focal cerebral ischemia-reperfusion in rats. ( Chen, L; Gong, Q; Xiao, C, 2003)
"Propofol (PPF) has a protective effect on myocardial ischemia-reperfusion (I/R) injury (MIRI)."1.72Propofol pretreatment alleviates mast cell degranulation by inhibiting SOC to protect the myocardium from ischemia-reperfusion injury. ( Guan, X; Juan, Z; Li, Y; Ma, R; Meng, Y; Sun, X; Wang, M, 2022)
"Desflurane had lower uptake than propofol (65 ± 21 × 10 vs 165 ± 51 × 10 g·mL·min/μmol; P = ."1.48Propofol Attenuates the Myocardial Protection Properties of Desflurane by Modulating Mitochondrial Permeability Transition. ( Andrews, DT; Heiberg, J; Royse, AG; Royse, CF, 2018)
"Isoflurane was inhaled at 1 MAC (0."1.35Cardioprotective effects of anesthetic preconditioning in rats with ischemia-reperfusion injury: propofol versus isoflurane. ( Li, SR; Lin, MT; Lu, LQ; Tao, X; Xu, Q, 2009)
"An esmolol infusion was started to control his persistent tachycardia but this depressed his myocardial contractility."1.29Thyrotoxicosis factitia in a post-aortocoronary bypass patient. ( Karski, JM; Redahan, C, 1994)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (10.26)18.2507
2000's17 (43.59)29.6817
2010's9 (23.08)24.3611
2020's9 (23.08)2.80

Authors

AuthorsStudies
Jiang, X1
Yan, M1
Zhang, MX1
Tian, QX1
Liu, JL1
Zangrillo, A1
Lomivorotov, VV1
Pasyuga, VV1
Belletti, A1
Gazivoda, G1
Monaco, F1
Nigro Neto, C1
Likhvantsev, VV1
Bradic, N1
Lozovskiy, A1
Lei, C1
Bukamal, NAR1
Silva, FS1
Bautin, AE1
Ma, J1
Yong, CY1
Carollo, C1
Kunstyr, J1
Wang, CY1
Grigoryev, EV1
Riha, H1
Wang, C2
El-Tahan, MR1
Scandroglio, AM1
Mansor, M1
Lembo, R1
Ponomarev, DN1
Bezerra, FJL1
Ruggeri, L1
Chernyavskiy, AM1
Xu, J1
Tarasov, DG1
Navalesi, P1
Yavorovskiy, A1
Bove, T1
Kuzovlev, A1
Hajjar, LA1
Landoni, G1
Cho, YJ1
Jung, DE1
Nam, K1
Bae, J1
Lee, S1
Jeon, Y1
Jang, JM1
Park, SB1
Yoon, JY1
Kwak, MS1
Cha, JM1
Li, Y1
Sun, X1
Juan, Z1
Guan, X1
Wang, M1
Meng, Y1
Ma, R1
Heybati, K1
Zhou, F1
Baltazar, M1
Poudel, K1
Ochal, D1
Ellythy, L1
Deng, J1
Chelf, CJ1
Welker, C1
Ramakrishna, H1
Lotz, C2
Stumpner, J2
Smul, TM2
Jing, H1
Zhao, L1
Cheng, J1
Qin, P1
Lin, H1
Heusch, G2
Behmenburg, F1
van Caster, P1
Bunte, S1
Brandenburger, T1
Heinen, A1
Hollmann, MW1
Huhn, R1
Meybohm, P1
Kohlhaas, M1
Stoppe, C1
Gruenewald, M1
Renner, J1
Bein, B1
Albrecht, M1
Cremer, J1
Coburn, M1
Schaelte, G1
Boening, A1
Niemann, B1
Sander, M1
Roesner, J1
Kletzin, F1
Mutlak, H1
Westphal, S1
Laufenberg-Feldmann, R1
Ferner, M1
Brandes, IF1
Bauer, M1
Stehr, SN1
Kortgen, A1
Wittmann, M1
Baumgarten, G1
Meyer-Treschan, T1
Kienbaum, P1
Heringlake, M1
Schoen, J1
Treskatsch, S1
Smul, T1
Wolwender, E1
Schilling, T1
Fuernau, G1
Bogatsch, H1
Brosteanu, O1
Hasenclever, D1
Zacharowski, K1
Heiberg, J1
Royse, CF2
Royse, AG2
Andrews, DT2
Gajardo, AIJ1
Karachon, L1
Bustamante, P1
Repullo, P1
Llancaqueo, M1
Sánchez, G1
Rodrigo, R1
Sindjelic, RP1
Vlajkovic, GP1
Lucic, M1
Koncar, I1
Kostic, D1
Davidovic, LB1
Rasmussen, T1
Follin, B1
Kastrup, J1
Christensen, TE1
Hammelev, KP1
Kjær, A1
Hasbak, P1
Shimony, A1
Almog, Y1
Zahger, D1
Kamada, N1
Kanaya, N1
Hirata, N1
Kimura, S1
Namiki, A1
Yildirim, V1
Doganci, S1
Aydin, A1
Bolcal, C1
Demirkilic, U1
Cosar, A1
Tao, X1
Lu, LQ1
Xu, Q1
Li, SR1
Lin, MT1
Blomeyer, C1
Redel, A1
Lange, M1
Roewer, N1
Kehl, F1
Kottenberg, E1
Thielmann, M1
Bergmann, L1
Heine, T1
Jakob, H1
Peters, J1
Sakabe, M1
Fujiki, A1
Inoue, H1
Chen, L1
Gong, Q1
Xiao, C1
Peláez, R1
Hortal, FJ1
Bastida, E1
Barrio, JM1
Riesgo, MJ1
Kulkarni, A1
Price, G1
Saxena, M1
Skowronski, G1
Barrington, MJ1
Kluger, R1
Watson, R1
Scott, DA1
Harris, KJ1
Maekawa, T1
Cho, S1
Takahashi, S1
Hara, T1
Tomiyasu, S1
Makita, T1
Sumikawa, K1
Higuchi, H1
Maeda, S1
Miyawaki, T1
Kohjitani, A1
Mori, T1
Ishida, R1
Egusa, M1
Shimada, M1
Jakobsen, CJ1
Berg, H1
Hindsholm, KB1
Faddy, N1
Sloth, E1
Choi, SU1
Lee, HW1
Lim, HJ1
Yoon, SM1
Chang, SH1
Roekaerts, PM1
Gerrits, HJ1
Timmerman, BE1
de Lange, S1
Hawkins, WJ1
Cohen, AT1
Redahan, C1
Karski, JM1
Cheng, DC1
Karski, J1
Peniston, C1
Asokumar, B1
Raveendran, G1
Carroll, J1
Nierenberg, H1
Roger, S1
Mickle, D1
Tong, J1
Zelovitsky, J1
David, T1
Sandler, A1
Pittarello, D1
Bonato, R1
Armellin, G1
Sorbara, C1
Hess, WC1
Ohe, A1
Bonome, C1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of TENS on Myocardial Protection in Patients Undergoing AVR[NCT03859115]30 participants (Actual)Interventional2019-03-15Completed
Remote Ischaemic Preconditioning for Heart Surgery[NCT01067703]Phase 31,400 participants (Actual)Interventional2010-12-31Terminated
Effect of Remote Ischemic Preconditioning in Patients Undergoing On-pump Coronary Artery Bypass Graft Surgery With Crystalloid Cardioplegic Arrest[NCT01406678]Phase 2/Phase 31,204 participants (Actual)Interventional2008-07-31Completed
Remote Ischemic Conditioning (RIC) in Recipients of Brain Death Donor Livers - A Feasibility and Safety Study[NCT02635347]31 participants (Actual)Interventional2015-11-30Completed
Protection of Heart, Brain and Kidney by Remote Ischemic Preconditioning in Patients Undergoing Transcatheter Aortic Valve Implantation - a Randomized, Single-blind Study[NCT02080299]Phase 2100 participants (Actual)Interventional2013-09-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Clavien-Dindo Grade IIIb or Higher - Number of Complications

In patients with Clavien-Dindo >/= IIIb complications, number of such complications per patient. (NCT02635347)
Timeframe: Post-op days 0-30

InterventionComplications (Median)
Remote Ischemic Conditioning (RIC) Group1
Historical Control Cohort0

Hospital LOS

Number of days in hospital post-transplant. Starting at post-op day 0 and ending on the calendar date that the patient is leaves the hospital, dies, or post-op day 90, whichever is soonest. (NCT02635347)
Timeframe: Post-op days 0 up to 90 days

Interventiondays (Median)
Remote Ischemic Conditioning (RIC) Group13
Historical Control Cohort10

Intensive Care Unit (ICU) Length of Stay (LOS)

Number of days in ICU post-transplant. Starting at post-op day 0 and ending on the calendar date that the patient is transferred out of ICU, dies, or post-op day 90, whichever is soonest. (NCT02635347)
Timeframe: Post-op days 0 up to 90 days

Interventiondays (Median)
Remote Ischemic Conditioning (RIC) Group3.5
Historical Control Cohort4

Intervention-related Pain Score

Median intervention-related pain score during each of the post-operative interventions, in extubated patients who are able to communicate. Using the Numerical Rating Scale (NRS, Ferrieira-Valente MA PAIN Volume 152, 2011), patients were asked to rate their pain following the intervention on a scale of 0-10 with 0 being no pain experienced to 10 as the maximum pain felt. (NCT02635347)
Timeframe: Post-op days 1-4

Interventionscores on a scale (Median)
Remote Ischemic Conditioning (RIC) Group5

Liver Allograft Survival

Percentage of patients with functioning allograft at 90 days post-transplant (NCT02635347)
Timeframe: Post-op day 90

Interventionpercentage of participants (Number)
Remote Ischemic Conditioning (RIC) Group90
Historical Control Cohort98.41

Number of Subjects Not Completing Intervention Protocol

Number of subjects that received fewer than 6 interventions,. (NCT02635347)
Timeframe: Pre-op - Post-op day 4

Interventionparticipants (Number)
Remote Ischemic Conditioning (RIC) Group9

Patient Survival

Percentage of patients alive at 90 days post-transplant (NCT02635347)
Timeframe: Post-op day 90

Interventionpercentage of participants (Number)
Remote Ischemic Conditioning (RIC) Group90.32
Historical Control Cohort98.41

Percentage of Participants Completing Entire Intervention Protocol

Proportion of enrolled liver recipients that complete all 6 remote ischemic conditioning (RIC) interventions. (NCT02635347)
Timeframe: Pre-op - Post-op day 4

Interventionpercentage of participants (Number)
Remote Ischemic Conditioning (RIC) Group70.96

Percentage of Participants Who Developed Acute Kidney Injury (AKI) Stages 2 or 3

"Percentage of participants who developed Acute Kidney Injury (AKI)~Based on Kidney Disease - Improving Global Outcomes (KDIGO) criteria, AKI criteria are:~Stage 2:~- 2.0-2.9 fold rise in serum creatinine from baseline~Stage 3:~> 3.0 fold rise in serum creatinine from baseline, or~Serum creatinine of > 4.0 mg/dL, with an acute (<48 hours) increase of 0.3 mg/dL in serum creatinine or subacute (< 7 days) increase in serum creatinine of 0.5 mg/dL, or~Initiation of renal replacement therapy." (NCT02635347)
Timeframe: Post-op days 0-7

Interventionpercentage of participants (Number)
Remote Ischemic Conditioning (RIC) Group20.0
Historical Control Cohort25.86

Percentage of Participants Who Developed Early Allograft Dysfunction (EAD)

"Percentage of participants who developed Early Allograft Dysfunction (EAD) which is defined as:~Aspartate Transaminase (AST) or Alanine Transaminase (ALT)> 2,000 U/L at any point within the first seven post-transplant days, or~Total Bilirubin (TB) > 10 mg/dL on postoperative day 7,or~International Normalized Ratio (INR)> 1.6 on postoperative day 7." (NCT02635347)
Timeframe: Post-op days 0-7

Interventionpercentage of participants (Number)
Remote Ischemic Conditioning (RIC) Group23.3
Historical Control Cohort39.68

Percentage of Participants Who Developed Prolonged Respiratory Insufficiency (PRI)

"Percentage of Participants who developed Prolonged Respiratory Insufficiency (PRI) defined as:~Ventilator support for >2 postoperative days after transplant, or~Reintubation after extubation, within 7 days of transplant. Patients who require brief re-intubation for an endoscopic, radiologic, or surgical procedure would not be considered to have PRI if they are extubated within 2 days of the end of the procedure." (NCT02635347)
Timeframe: Post-op days 0-7

Interventionpercentage of participants (Number)
Remote Ischemic Conditioning (RIC) Group33.3
Historical Control Cohort28.57

Presence of Clavien-Dindo Grade IIIb or Higher Complications

"Percentage of patients with Clavien-Dindo >/= grade III b complications (Dindo D, Demartines N, Clavien P, Annals of Surgery 2004).~The Clavien-Dindo Complications grade ranges from Grade I (Any deviation from the normal postoperative course without the need for pharmacological treatment or surgical, endoscopic and radiological interventions Allowed therapeutic regimens are: drugs as antiemetics, antipyretics, analgetics, diuretics and electrolytes and physiotherapy. This grade also includes wound infections opened at the bedside) to Grade V (Death). Grade IIIb would be any intervention requiring general anesthesia." (NCT02635347)
Timeframe: Post-op days 0-30

Interventionpercentage of participants (Number)
Remote Ischemic Conditioning (RIC) Group51.1
Historical Control Cohort47.62

Time to Dialysis Discontinuation

In patients who are receiving dialysis pre-op, time to discontinuation of dialysis, if occurring within 90 days of transplantation. (NCT02635347)
Timeframe: Post-op days 0-90

Interventiondays (Median)
Remote Ischemic Conditioning (RIC) Group2
Historical Control Cohort15.5

Withdrawal of Consent Due to Pain

- Withdrawal of consent due to discomfort/pain in the lower extremity (NCT02635347)
Timeframe: Pre-op - Post-op day 7

Interventionparticipants (Number)
Remote Ischemic Conditioning (RIC) Group6
Historical Control Cohort0

Reviews

3 reviews available for propofol and Cardiovascular Stroke

ArticleYear
Appraisal of Postoperative Outcomes of Volatile and Intravenous Anesthetics: A Network Meta-Analysis of Patients Undergoing Cardiac Surgery.
    Journal of cardiothoracic and vascular anesthesia, 2023, Volume: 37, Issue:11

    Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Cardiac Surgical Procedures; Humans; Midaz

2023
Remote Ischemic Conditioning in Cardiovascular Surgery.
    Journal of cardiovascular pharmacology and therapeutics, 2017, Volume: 22, Issue:4

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Cardiac Surgical Procedures; Comorbidity; Humans;

2017
[Remifentanil in heart surgery].
    Revista espanola de anestesiologia y reanimacion, 2001, Volume: 48, Issue:10

    Topics: Analgesics; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intrave

2001

Trials

9 trials available for propofol and Cardiovascular Stroke

ArticleYear
Effect of Volatile Anesthetics on Myocardial Infarction After Coronary Artery Surgery: A Post Hoc Analysis of a Randomized Trial.
    Journal of cardiothoracic and vascular anesthesia, 2022, Volume: 36, Issue:8 Pt A

    Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Coronary Artery Bypass; Humans; Middle Aged

2022
Effects of transcutaneous electrical nerve stimulation on myocardial protection in patients undergoing aortic valve replacement: a randomized clinical trial.
    BMC anesthesiology, 2022, 03-09, Volume: 22, Issue:1

    Topics: Animals; Aortic Valve; Humans; Myocardial Infarction; Propofol; Rats; Sevoflurane; Transcutaneous El

2022
RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study: Myocardial Dysfunction, Postoperative Neurocognitive Dysfunction, and 1 Year Follow-Up.
    Journal of the American Heart Association, 2018, 03-26, Volume: 7, Issue:7

    Topics: Anesthetics, Intravenous; Cardiac Surgical Procedures; Cognition; Double-Blind Method; Echocardiogra

2018
Cardioprotective effects of sevoflurane, isoflurane, and propofol in coronary surgery patients: a randomized controlled study.
    The heart surgery forum, 2009, Volume: 12, Issue:1

    Topics: Administration, Inhalation; Aged; Anesthetics, Inhalation; Cardiotonic Agents; Coronary Artery Bypas

2009
Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trial.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intraveno

2012
Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trial.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intraveno

2012
Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trial.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intraveno

2012
Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trial.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intraveno

2012
Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trial.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intraveno

2012
Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trial.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intraveno

2012
Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trial.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intraveno

2012
Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trial.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intraveno

2012
Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trial.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intraveno

2012
Epidural anesthesia for coronary artery bypass surgery compared with general anesthesia alone does not reduce biochemical markers of myocardial damage.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:4

    Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenous; Biomarkers; Cardiomyopath

2005
Continuous infusions of alfentanil and propofol for coronary artery surgery.
    Journal of cardiothoracic and vascular anesthesia, 1995, Volume: 9, Issue:4

    Topics: Alfentanil; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Coron

1995
Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial.
    The Journal of thoracic and cardiovascular surgery, 1996, Volume: 112, Issue:3

    Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Apnea; Catecholamines;

1996
[Alterations in left ventricular-arterial coupling and mechanical efficiency produced by remifentanil during cardiac anesthesia].
    Minerva anestesiologica, 2001, Volume: 67, Issue:3

    Topics: Aged; Anesthetics, Intravenous; Aorta; Cardiovascular Agents; Combined Modality Therapy; Coronary Ar

2001

Other Studies

27 other studies available for propofol and Cardiovascular Stroke

ArticleYear
Comparing the impact on the prognosis of acute myocardial infarction critical patients of using midazolam, propofol, and dexmedetomidine for sedation.
    BMC cardiovascular disorders, 2021, 12-07, Volume: 21, Issue:1

    Topics: Aged; Aged, 80 and over; Coronary Care Units; Critical Illness; Databases, Factual; Dexmedetomidine;

2021
[The myocardial protective effect of propofol on rats with experimental myocardial infarction and its mechanism].
    Sheng li xue bao : [Acta physiologica Sinica], 2021, Dec-25, Volume: 73, Issue:6

    Topics: Animals; Cardiotonic Agents; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Infa

2021
Gastrointestinal and non-gastrointestinal complication rates associated with diagnostic esophagogastroduodenoscopy under sedation.
    Medicine, 2022, May-13, Volume: 101, Issue:19

    Topics: Aged; Conscious Sedation; Endoscopy, Digestive System; Humans; Hypnotics and Sedatives; Midazolam; M

2022
Propofol pretreatment alleviates mast cell degranulation by inhibiting SOC to protect the myocardium from ischemia-reperfusion injury.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 150

    Topics: Animals; Apoptosis; Calcium; Cell Degranulation; Mast Cells; Myocardial Infarction; Myocardial Reper

2022
Sevoflurane as opposed to propofol anesthesia preserves mitochondrial function and alleviates myocardial ischemia/reperfusion injury.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 129

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Disease Models, Animal; Electron Transpo

2020
Propofol protects cardiomyocytes from hypoxia/reoxygenation injury via regulating MALAT1/miR-206/ATG3 axis.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:10

    Topics: Animals; Apoptosis; Autophagy-Related Proteins; Cell Hypoxia; Cell Line; Disease Models, Animal; Dow

2021
Impact of Anesthetic Regimen on Remote Ischemic Preconditioning in the Rat Heart In Vivo.
    Anesthesia and analgesia, 2018, Volume: 126, Issue:4

    Topics: Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Disease Models, Anim

2018
Propofol Attenuates the Myocardial Protection Properties of Desflurane by Modulating Mitochondrial Permeability Transition.
    Anesthesia and analgesia, 2018, Volume: 127, Issue:2

    Topics: Anesthesia; Anesthetics, Intravenous; Animals; Cardiotonic Agents; Deoxyglucose; Desflurane; Drug Ad

2018
Autonomic imbalance in cardiac surgery: A potential determinant of the failure in remote ischemic preconditioning.
    Medical hypotheses, 2018, Volume: 118

    Topics: Animals; Cardiac Surgical Procedures; Chronic Disease; Comorbidity; Heart; Humans; Ischemic Precondi

2018
Incidence of and indications for conversion of cervical plexus block to general anesthesia in patients undergoing carotid surgery: a single center experience.
    The Journal of cardiovascular surgery, 2015, Volume: 56, Issue:3

    Topics: Aged; Anesthesia, General; Anesthetics, Intravenous; Anesthetics, Local; Carotid Arteries; Cervical

2015
Myocardial perfusion of infarcted and normal myocardium in propofol-anesthetized minipigs using (82)Rubidium PET.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2016, Volume: 23, Issue:3

    Topics: Anesthetics, Intravenous; Animals; Blood Flow Velocity; Coronary Circulation; Myocardial Infarction;

2016
Propofol infusion syndrome: a rare cause of multi-organ failure in a man with complicated myocardial infarction.
    The Israel Medical Association journal : IMAJ, 2008, Volume: 10, Issue:4

    Topics: Anesthetics, Intravenous; Humans; Male; Middle Aged; Multiple Organ Failure; Myocardial Infarction;

2008
Cardioprotective effects of propofol in isolated ischemia-reperfused guinea pig hearts: role of KATP channels and GSK-3beta.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2008, Volume: 55, Issue:9

    Topics: Action Potentials; Anesthetics, Intravenous; Animals; Cardiotonic Agents; Coronary Circulation; Glyc

2008
Functional comparison of anaesthetic agents during myocardial ischaemia-reperfusion using pressure-volume loops.
    British journal of anaesthesia, 2009, Volume: 103, Issue:5

    Topics: Anesthetics; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Desflurane; Drug Evaluation

2009
Cardioprotective effects of anesthetic preconditioning in rats with ischemia-reperfusion injury: propofol versus isoflurane.
    Journal of Zhejiang University. Science. B, 2009, Volume: 10, Issue:10

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Apoptosis; Cardiotonic Agents; Drug Inte

2009
Propofol inhibits desflurane-induced preconditioning in rabbits.
    Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:2

    Topics: Animals; Desflurane; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Myocardial Infarction;

2011
Propofol induced marked prolongation of QT interval in a patient with acute myocardial infarction.
    Anesthesiology, 2002, Volume: 97, Issue:1

    Topics: Aged; Anesthetics, Intravenous; Electrocardiography; Female; Humans; Myocardial Infarction; Propofol

2002
Effects of propofol, midazolam and thiopental sodium on outcome and amino acids accumulation in focal cerebral ischemia-reperfusion in rats.
    Chinese medical journal, 2003, Volume: 116, Issue:2

    Topics: Adenosine Triphosphate; Animals; Brain; Brain Edema; Brain Ischemia; Excitatory Amino Acids; Male; M

2003
Narcolepsy and cardiac surgery: can anesthesia with propofol and remifentanil be safe?
    Journal of cardiothoracic and vascular anesthesia, 2004, Volume: 18, Issue:2

    Topics: Aged; Anesthesia, General; Anesthetics, Intravenous; Atracurium; Cardiac Surgical Procedures; Cardio

2004
Difficult extubation: calming the sympathetic storm.
    Anaesthesia and intensive care, 2004, Volume: 32, Issue:3

    Topics: Aged; Conscious Sedation; Device Removal; Dexmedetomidine; Humans; Hypertension; Hypnotics and Sedat

2004
Negative inotropic action of propofol is enhanced in the acute ischemic myocardium of dogs.
    Journal of anesthesia, 2005, Volume: 19, Issue:2

    Topics: Animals; Calcium; Cerebrovascular Circulation; Chloralose; Depression, Chemical; Dogs; Myocardial Co

2005
Dental management of a patient with takotsubo cardiomyopathy: a case report.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2007, Volume: 103, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthetics, Intravenous; Cardiomyopathies; Conscious Sedation; Dental Ca

2007
The influence of propofol versus sevoflurane anesthesia on outcome in 10,535 cardiac surgical procedures.
    Journal of cardiothoracic and vascular anesthesia, 2007, Volume: 21, Issue:5

    Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Arrhythmias, Cardiac;

2007
The effects of propofol on cardiac function after 4 hours of cold cardioplegia and reperfusion.
    Journal of cardiothoracic and vascular anesthesia, 2007, Volume: 21, Issue:5

    Topics: Anesthetics, Intravenous; Animals; Apoptosis; Bradykinin; Coronary Vessels; Glucose; Heart; Heart Ar

2007
Fatal myocardial failure associated with a propofol infusion in a child.
    Anaesthesia, 1995, Volume: 50, Issue:6

    Topics: Child; Conscious Sedation; Humans; Myocardial Infarction; Propofol

1995
Thyrotoxicosis factitia in a post-aortocoronary bypass patient.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:10

    Topics: Adrenergic beta-Antagonists; Amrinone; Angina, Unstable; Coronary Artery Bypass; Humans; Isoquinolin

1994
Does ketamine/propofol anesthesia possess antiarrhythmogenic quality? A perioperative study in aortocoronary bypass patients.
    European journal of medical research, 2001, Dec-17, Volume: 6, Issue:12

    Topics: Aged; Anti-Arrhythmia Agents; Body Temperature Regulation; Coronary Artery Bypass; Electrocardiograp

2001