propofol has been researched along with Cardiotoxicity in 3 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Isolated perfused newborn mouse hearts were exposed to a toxic dose of propofol or intralipid for 30-min." | 5.72 | Modeling propofol-induced cardiotoxicity in the isolated-perfused newborn mouse heart. ( Barajas, MB; Griffiths, KK; Levy, RJ; Sun, L; Wang, A; Yang, G, 2022) |
| " Isolated perfused newborn mouse hearts were exposed to a toxic dose of propofol or intralipid for 30-min." | 1.72 | Modeling propofol-induced cardiotoxicity in the isolated-perfused newborn mouse heart. ( Barajas, MB; Griffiths, KK; Levy, RJ; Sun, L; Wang, A; Yang, G, 2022) |
| "Propofol can cause considerable developmental neurotoxicity and has known activity on the heart." | 1.56 | Developmental and cardiac toxicities of propofol in zebrafish larvae. ( Chen, L; Liu, J; Luo, X; Xie, H; Zhang, Y, 2020) |
| "Propofol was the strongest depressant among the 3 compounds tested, exhibiting the largest decrease in contraction velocity, depression rate, and beating frequency." | 1.56 | An In Vitro Model for Identifying Cardiac Side Effects of Anesthetics. ( Bertaccini, EJ; Blau, HM; Chang, ACH; Chang, ACY; Davies, MF; Holbrook, C; Nicin, L; Weber, GJ, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barajas, MB | 1 |
| Wang, A | 1 |
| Griffiths, KK | 1 |
| Sun, L | 1 |
| Yang, G | 1 |
| Levy, RJ | 1 |
| Luo, X | 1 |
| Chen, L | 1 |
| Zhang, Y | 1 |
| Liu, J | 1 |
| Xie, H | 1 |
| Chang, ACY | 1 |
| Chang, ACH | 1 |
| Nicin, L | 1 |
| Weber, GJ | 1 |
| Holbrook, C | 1 |
| Davies, MF | 1 |
| Blau, HM | 1 |
| Bertaccini, EJ | 1 |
3 other studies available for propofol and Cardiotoxicity
| Article | Year |
|---|---|
Modeling propofol-induced cardiotoxicity in the isolated-perfused newborn mouse heart.
Topics: Animals; Animals, Newborn; Arrhythmias, Cardiac; Cardiotoxicity; Heart; Humans; Mice; Myocytes, Card | 2022 |
Developmental and cardiac toxicities of propofol in zebrafish larvae.
Topics: Animals; Cardiotoxicity; Embryo, Nonmammalian; Gene Expression Regulation, Developmental; Hypnotics | 2020 |
An In Vitro Model for Identifying Cardiac Side Effects of Anesthetics.
Topics: Adult; Anesthetics, Intravenous; Cardiotoxicity; Cell Line; Etomidate; Female; Heart Diseases; Heart | 2020 |