propofol has been researched along with Cardiomegaly in 4 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We hypothesized that propofol, an anesthetic with antioxidant capacity, may attenuate hyperglycemia-induced oxidative stress in cardiomyocytes via enhancing heme oxygenase-1 activation and ameliorate hyperglycemia-induced cardiac hypertrophy and apoptosis via heme oxygenase-1/signal transducer and activator of transcription 3 signaling and improve cardiac function in diabetes." | 7.80 | Propofol ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction via heme oxygenase-1/signal transducer and activator of transcription 3 signaling pathway in rats. ( Cheung, CW; Clanachan, AS; Fang, X; Hung, V; Irwin, MG; Lei, S; Li, H; Mao, X; Wong, GT; Xia, Z; Xia, ZY; Xu, J, 2014) |
| " We hypothesized that propofol, an anesthetic with antioxidant capacity, may attenuate hyperglycemia-induced oxidative stress in cardiomyocytes via enhancing heme oxygenase-1 activation and ameliorate hyperglycemia-induced cardiac hypertrophy and apoptosis via heme oxygenase-1/signal transducer and activator of transcription 3 signaling and improve cardiac function in diabetes." | 3.80 | Propofol ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction via heme oxygenase-1/signal transducer and activator of transcription 3 signaling pathway in rats. ( Cheung, CW; Clanachan, AS; Fang, X; Hung, V; Irwin, MG; Lei, S; Li, H; Mao, X; Wong, GT; Xia, Z; Xia, ZY; Xu, J, 2014) |
| "Propofol is a general anesthetic that possesses antioxidant action." | 1.35 | Propofol depresses angiotensin II-induced cardiomyocyte hypertrophy in vitro. ( Yang, L; Yao, SL; Zou, XJ, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, J | 1 |
| Li, H | 1 |
| Irwin, MG | 1 |
| Xia, ZY | 1 |
| Mao, X | 1 |
| Lei, S | 1 |
| Wong, GT | 1 |
| Hung, V | 1 |
| Cheung, CW | 1 |
| Fang, X | 1 |
| Clanachan, AS | 1 |
| Xia, Z | 1 |
| Li Volti, G | 1 |
| Murabito, P | 1 |
| King, N | 1 |
| Al Shaama, M | 1 |
| Suleiman, MS | 1 |
| Zou, XJ | 1 |
| Yang, L | 1 |
| Yao, SL | 1 |
4 other studies available for propofol and Cardiomegaly
| Article | Year |
|---|---|
Propofol ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction via heme oxygenase-1/signal transducer and activator of transcription 3 signaling pathway in rats.
Topics: Activating Transcription Factor 3; Animals; Antioxidants; Apoptosis; Cardiomegaly; Diabetes Mellitus | 2014 |
Pharmacologic induction of heme oxygenase-1: it is time to take it seriously*.
Topics: Activating Transcription Factor 3; Animals; Cardiomegaly; Diabetes Mellitus, Experimental; Diabetes | 2014 |
Propofol improves recovery of the isolated working hypertrophic heart from ischaemia-reperfusion.
Topics: Animals; Cardiac Output; Cardiomegaly; In Vitro Techniques; Myocardial Reperfusion; Myocytes, Cardia | 2012 |
Propofol depresses angiotensin II-induced cardiomyocyte hypertrophy in vitro.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Survival; Cells, Cultured; Cytoprotection; Extracellular | 2008 |