propofol has been researched along with Cardiac Output, Low in 10 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors report a case of short-term high-dose propofol-related metabolic acidosis in a 3-year-old girl." | 7.74 | Early propofol infusion syndrome following cerebral angiographic embolization for giant aneurysm repair. Case report. ( Muhonen, MG; Nwagwu, CI; Westhout, FD, 2007) |
| "Propofol is increasingly used for the treatment of status epilepticus due to the ease of use and tolerability, even if safety data from randomized clinical trials are lacking." | 7.74 | Propofol-associated fatal myocardial failure and rhabdomyolysis in an adult with status epilepticus. ( Harris, BT; Jobst, BC; Zarovnaya, EL, 2007) |
| "The authors report a case of short-term high-dose propofol-related metabolic acidosis in a 3-year-old girl." | 3.74 | Early propofol infusion syndrome following cerebral angiographic embolization for giant aneurysm repair. Case report. ( Muhonen, MG; Nwagwu, CI; Westhout, FD, 2007) |
| "Propofol is increasingly used for the treatment of status epilepticus due to the ease of use and tolerability, even if safety data from randomized clinical trials are lacking." | 3.74 | Propofol-associated fatal myocardial failure and rhabdomyolysis in an adult with status epilepticus. ( Harris, BT; Jobst, BC; Zarovnaya, EL, 2007) |
| " We compared the effects of intravenous anesthesia (propofol) and inhalational anesthesia (isoflurane) on multipoint mean [pulmonary arterial pressure (Ppa)-pulmonary arterial occluded pressure (PpaO)]/cardiac output (Q) plots and on pulmonary vascular impedance (PVZ) spectra in eight dogs alternatively ventilated in hyperoxia [inspired O2 fraction (FIO2) 0." | 3.68 | Pulmonary vascular impedance vs. resistance in hypoxic and hyperoxic dogs: effects of propofol and isoflurane. ( Brimioulle, S; Ewalenko, P; Holoye, A; Naeije, R; Stefanidis, C, 1993) |
| "Propofol was associated with an increase in myocardial Bcl-2 protein expression (P = 0." | 2.82 | Propofol cardioprotection for on-pump aortocoronary bypass surgery in patients with type 2 diabetes mellitus (PRO-TECT II): a phase 2 randomized-controlled trial. ( Ansley, DM; Chen, DD; Choi, PT; Cook, RC; Raedschelders, K; Wang, B, 2016) |
| "Low cardiac output was defined as a cardiac index less than 2." | 2.68 | Comparison of the use of a propofol infusion in cardiac surgical patients with normal and low cardiac output states. ( Bell, JH; Sartain, J; Sherry, KM; Wilkinson, GA, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ansley, DM | 1 |
| Raedschelders, K | 1 |
| Choi, PT | 1 |
| Wang, B | 1 |
| Cook, RC | 1 |
| Chen, DD | 1 |
| Kang, TM | 1 |
| Patermann, B | 1 |
| Buzello, S | 1 |
| Dück, M | 1 |
| Paul, M | 1 |
| Kampe, S | 1 |
| Westhout, FD | 1 |
| Muhonen, MG | 1 |
| Nwagwu, CI | 1 |
| Zarovnaya, EL | 1 |
| Jobst, BC | 1 |
| Harris, BT | 1 |
| Sherry, KM | 2 |
| Sartain, J | 2 |
| Bell, JH | 1 |
| Wilkinson, GA | 2 |
| Bell, J | 1 |
| Ewalenko, P | 1 |
| Stefanidis, C | 1 |
| Holoye, A | 1 |
| Brimioulle, S | 1 |
| Naeije, R | 1 |
| Rubio-Martínez, CJ | 1 |
| Lang-Lenton León, M | 1 |
| Rodríguez-Ponte-Cuadrillero, EM | 1 |
| Boralla-Rivera, G | 1 |
| Ramírez-Felipe, J | 1 |
| Vallejo-Gallego, I | 1 |
| Kanouzi-Masuh, G | 1 |
| Cruz-Benavides, F | 1 |
| Neff, SP | 1 |
| Futter, ME | 1 |
| Anderson, BJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PRO-TECT II: Propofol Cardioprotection for Type II Diabetics[NCT00734383] | Phase 2/Phase 3 | 137 participants (Actual) | Interventional | 2005-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for propofol and Cardiac Output, Low
| Article | Year |
|---|---|
Propofol infusion syndrome in critically ill patients.
Topics: Adult; Anesthetics, Intravenous; Cardiac Output, Low; Child; Critical Care; Critical Illness; Humans | 2002 |
2 trials available for propofol and Cardiac Output, Low
| Article | Year |
|---|---|
Propofol cardioprotection for on-pump aortocoronary bypass surgery in patients with type 2 diabetes mellitus (PRO-TECT II): a phase 2 randomized-controlled trial.
Topics: Aged; Anesthetics, Intravenous; Cardiac Output, Low; Coronary Artery Bypass; Diabetes Mellitus, Type | 2016 |
Comparison of the use of a propofol infusion in cardiac surgical patients with normal and low cardiac output states.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Cardiac Output, Low; C | 1995 |
7 other studies available for propofol and Cardiac Output, Low
| Article | Year |
|---|---|
Accidental tenfold overdose of propofol in a 6-month old infant undergoing elective craniosynostosis repair.
Topics: Anesthetics, Intravenous; Cardiac Output, Low; Craniosynostoses; Drug Overdose; Humans; Infant; Intr | 2004 |
Early propofol infusion syndrome following cerebral angiographic embolization for giant aneurysm repair. Case report.
Topics: Acidosis; Anesthetics, Intravenous; Aneurysm; Balloon Occlusion; Cardiac Output, Low; Carotid Artery | 2007 |
Propofol-associated fatal myocardial failure and rhabdomyolysis in an adult with status epilepticus.
Topics: Acidosis; Adult; Age Factors; Anticonvulsants; Cardiac Output, Low; Cardiomyopathies; Fatal Outcome; | 2007 |
Propofol and fentanyl anaesthesia for patients with low cardiac output state undergoing cardiac surgery: comparison with high-dose fentanyl anaesthesia.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Intravenous; Cardiac Output, | 1994 |
Pulmonary vascular impedance vs. resistance in hypoxic and hyperoxic dogs: effects of propofol and isoflurane.
Topics: Anesthesia; Animals; Blood Gas Analysis; Cardiac Output, High; Cardiac Output, Low; Dogs; Hypoxia; I | 1993 |
[Anesthesia in laparoscopic cholecystectomy with CO2: comparison of the hemodynamic and respiratory behavior using 2 different anesthetic techniques].
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, | 1996 |
Fatal outcome after propofol sedation in children.
Topics: Acidosis; Arrhythmias, Cardiac; Cardiac Output, Low; Cause of Death; Child; Creatine Kinase; Dantrol | 1997 |