propofol has been researched along with Carcinoma, Squamous Cell in 19 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "BACKGROUND This study was done to verify whether propofol could inhibit esophageal squamous cell carcinoma (ESCC) cell line EC9706 cell migration and invasion by targeting SOX4." | 7.85 | Propofol Suppresses Esophageal Squamous Cell Carcinoma Cell Migration and Invasion by Down-Regulation of Sex-Determining Region Y-box 4 (SOX4). ( Ji, P; Li, JJ; Zhou, CL, 2017) |
| "BACKGROUND This study was done to verify whether propofol could inhibit esophageal squamous cell carcinoma (ESCC) cell line EC9706 cell migration and invasion by targeting SOX4." | 3.85 | Propofol Suppresses Esophageal Squamous Cell Carcinoma Cell Migration and Invasion by Down-Regulation of Sex-Determining Region Y-box 4 (SOX4). ( Ji, P; Li, JJ; Zhou, CL, 2017) |
| "5‑fluorouracil (5‑FU) is a commonly used treatment for OSCC, but cells typically display resistance to the drug." | 1.72 | Propofol induces apoptosis and ameliorates 5‑fluorouracil resistance in OSCC cells by reducing the expression and secretion of amphiregulin. ( Che, PC; Chen, JC; Chen, MS; Hsieh, MJ; Lee, IN; Wu, YP; Yang, KS, 2022) |
| "Propofol treatment inhibited cell proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT), but promoted apoptosis and induced cell cycle arrest in OSCC cells." | 1.72 | Propofol prevents the aggressive progression of oral squamous cell carcinoma via regulating circ_0005623/miR-195-5p/HOXB7 axis. ( Cao, C; Xu, Y; Zhang, X, 2022) |
| "Propofol treatment significantly promoted cell migration and invasion of OSCC." | 1.56 | Propofol facilitates migration and invasion of oral squamous cell carcinoma cells by upregulating SNAI1 expression. ( Jiang, H; Li, C; Li, W; Peng, J; Wang, H; Xia, M, 2020) |
| " The dosage of propofol recommended in these guidelines is, however, based on one single study." | 1.39 | [Palliative sedation in a man with oral cancer; the Royal Dutch Medical Association guidelines not always sufficient]. ( Broekhoff, FJ; Dompeling, EC; Smelt, WL; Vos-Westerman, JH; Wulffraat, ET, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 10 (52.63) | 24.3611 |
| 2020's | 4 (21.05) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, KS | 1 |
| Che, PC | 1 |
| Hsieh, MJ | 1 |
| Lee, IN | 1 |
| Wu, YP | 1 |
| Chen, MS | 1 |
| Chen, JC | 1 |
| Gao, C | 1 |
| Ren, C | 1 |
| Liu, Z | 1 |
| Zhang, L | 1 |
| Tang, R | 1 |
| Li, X | 1 |
| Li, C | 1 |
| Xia, M | 1 |
| Wang, H | 1 |
| Li, W | 1 |
| Peng, J | 1 |
| Jiang, H | 1 |
| Rezniczek, GA | 1 |
| Hecken, JM | 1 |
| Rehman, S | 1 |
| Dogan, A | 1 |
| Tempfer, CB | 1 |
| Hilal, Z | 1 |
| Cao, C | 1 |
| Zhang, X | 1 |
| Xu, Y | 1 |
| Conte, SC | 1 |
| Spagnol, G | 1 |
| Confalonieri, M | 1 |
| Brizi, B | 1 |
| Smelt, WL | 1 |
| Wulffraat, ET | 1 |
| Broekhoff, FJ | 1 |
| Dompeling, EC | 1 |
| Vos-Westerman, JH | 1 |
| Xu, YB | 2 |
| Du, QH | 1 |
| Zhang, MY | 1 |
| Yun, P | 1 |
| He, CY | 1 |
| Guo, XG | 1 |
| Wang, S | 1 |
| Zhuang, J | 1 |
| Liu, S | 1 |
| Gu, X | 1 |
| Zhu, L | 1 |
| Wu, G | 1 |
| Zhou, H | 1 |
| Song, Y | 1 |
| Wu, C | 1 |
| Zhou, CL | 1 |
| Li, JJ | 1 |
| Ji, P | 1 |
| Dueñas, N | 1 |
| Zaballos, M | 1 |
| Zhang, LM | 1 |
| Zhang, MX | 1 |
| Wang, N | 1 |
| Duan, XY | 1 |
| Zhou, SN | 1 |
| Wang, JS | 1 |
| Jing, GX | 1 |
| Sanz Carabaña, MP | 1 |
| Nozal Mateo, B | 1 |
| Ariño Irujo, J | 1 |
| López Timoneda, F | 1 |
| Ohno, S | 1 |
| Kobayashi, K | 1 |
| Uchida, S | 1 |
| Amano, O | 1 |
| Sakagami, H | 1 |
| Nagasaka, H | 1 |
| Kunimatsu, T | 1 |
| Misaki, T | 1 |
| Hirose, N | 1 |
| Tsuboi, E | 1 |
| Takahashi, I | 1 |
| Ohki, H | 1 |
| Oi, Y | 1 |
| Matsumoto, M | 1 |
| Tanaka, H | 1 |
| Bley, CR | 1 |
| Roos, M | 1 |
| Price, J | 1 |
| Ruess-Melzer, K | 1 |
| Buchholz, J | 1 |
| Poirier, V | 1 |
| Kaser-Hotz, B | 1 |
| Perera, ER | 1 |
| Vidic, DM | 1 |
| Zivot, J | 1 |
| Leonard, IE | 1 |
| Myles, PS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Large Loop Excision of the Transformation Zone (LLETZ) With Versus Without Intraoperative Application of Lugol's Iodine in Women With Cervical Dysplasia: a Prospective Randomized Trial[NCT05132114] | 216 participants (Anticipated) | Interventional | 2022-01-17 | Recruiting | |||
| Large Loop Excision of the Transformatione Zone Under General Versus Local Anesthesia: a Randomized Trial.[NCT03494686] | 229 participants (Actual) | Interventional | 2018-04-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for propofol and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes | 2020 |
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes | 2020 |
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes | 2020 |
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes | 2020 |
Effects of propofol and sevoflurane on perioperative immune response in patients undergoing laparoscopic radical hysterectomy for cervical cancer.
Topics: Adenocarcinoma; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Squamous Cell; CD4-CD8 | 2016 |
17 other studies available for propofol and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
Propofol induces apoptosis and ameliorates 5‑fluorouracil resistance in OSCC cells by reducing the expression and secretion of amphiregulin.
Topics: Amphiregulin; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Squamous Cell; Cell Proliferati | 2022 |
GAS5, a FoxO1-actived long noncoding RNA, promotes propofol-induced oral squamous cell carcinoma apoptosis by regulating the miR-1297-GSK3β axis.
Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Pr | 2019 |
Propofol facilitates migration and invasion of oral squamous cell carcinoma cells by upregulating SNAI1 expression.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Movement; Cell Proliferation; Gene Expression Regulation, | 2020 |
Propofol prevents the aggressive progression of oral squamous cell carcinoma via regulating circ_0005623/miR-195-5p/HOXB7 axis.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Head and Neck Neoplasms; Homeodomain Proteins; Humans; M | 2022 |
Deep sedation versus minimal sedation during endobronchial ultrasound transbronchial needle aspiration.
Topics: Adenocarcinoma; Adjuvants, Anesthesia; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Ant | 2018 |
[Palliative sedation in a man with oral cancer; the Royal Dutch Medical Association guidelines not always sufficient].
Topics: Carcinoma, Squamous Cell; Conscious Sedation; Humans; Hypnotics and Sedatives; Male; Midazolam; Midd | 2013 |
Propofol suppresses proliferation, invasion and angiogenesis by down-regulating ERK-VEGF/MMP-9 signaling in Eca-109 esophageal squamous cell carcinoma cells.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Esophageal Neoplasm | 2013 |
Propofol suppresses invasion, angiogenesis and survival of EC-1 cells in vitro by regulation of S100A4 expression.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Dose-Response Relation | 2015 |
Propofol Suppresses Esophageal Squamous Cell Carcinoma Cell Migration and Invasion by Down-Regulation of Sex-Determining Region Y-box 4 (SOX4).
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Esop | 2017 |
[Anesthesia for parathyroidectomy in an elderly patient with dermatomyositis and high risk of bronchial aspiration].
Topics: Aged, 80 and over; Androstanols; Anesthesia, Intravenous; Anesthetics, Intravenous; Carcinoma, Squam | 2009 |
[Effect of low dose propofol on biological behavior of esophageal squamous cell carcinoma cell line Eca109].
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Respo | 2011 |
[Anesthetic considerations in Miller Fisher syndrome].
Topics: Anesthesia, Intravenous; Atracurium; Biopsy; Carcinoma, Squamous Cell; Epilepsies, Partial; Hernia, | 2011 |
Cytotoxicity and type of cell death induced by midazolam in human oral normal and tumor cells.
Topics: Anesthetics, Intravenous; Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Diazepam; DNA Frag | 2012 |
Postoperative mental disorder following prolonged oral surgery.
Topics: Age Factors; Anesthetics, Intravenous; Blood Loss, Surgical; Carcinoma, Squamous Cell; Delirium; Fem | 2004 |
Clinical assessment of repeated propofol-associated anesthesia in cats.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Blood Pressure; Carcinoma, Squamous Cell | 2007 |
Carinal resection with two high-frequency jet ventilation delivery systems.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Carcinoma, Squamous Cell; High-Frequency Jet | 1993 |
Target-controlled intravenous anaesthesia with bispectral index monitoring for thoracotomy in a patient with severely impaired left ventricular function.
Topics: Aged; Analgesia, Epidural; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intrave | 2000 |