propofol has been researched along with Carcinoma, Non-Small Cell Lung in 12 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol may help to protect against ischaemic acute kidney injury (AKI); however, research on this topic is sparse." | 7.91 | Effect of sevoflurane-based or propofol-based anaesthesia on the incidence of postoperative acute kidney injury: A retrospective propensity score-matched analysis. ( Han, S; Jheon, S; Ji, E; Kim, J; Kim, K; Oh, TK, 2019) |
| "Limb RIPC attenuates acute lung injury via improving intraoperative pulmonary oxygenation in patients without severe pulmonary disease after lung resection under propofol-remifentanil anesthesia." | 5.19 | Limb remote ischemic preconditioning attenuates lung injury after pulmonary resection under propofol-remifentanil anesthesia: a randomized controlled study. ( Huang, WQ; Li, C; Li, YS; Liu, KX; Wu, Y; Xu, M, 2014) |
| "Propofol may help to protect against ischaemic acute kidney injury (AKI); however, research on this topic is sparse." | 3.91 | Effect of sevoflurane-based or propofol-based anaesthesia on the incidence of postoperative acute kidney injury: A retrospective propensity score-matched analysis. ( Han, S; Jheon, S; Ji, E; Kim, J; Kim, K; Oh, TK, 2019) |
| "Propofol functions as a tumor-inhibitor drug by regulating microRNAs (miRNAs)." | 1.91 | Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis. ( Han, B; Liang, L; Liu, Y; Zhang, Q, 2023) |
| "Propofol-based TIVA was associated with better RFS and OS than inhalation anesthesia in patients with stage I/II NSCLC who underwent curative resection." | 1.91 | Effect of total intravenous versus inhalation anesthesia on long-term oncological outcomes in patients undergoing curative resection for early-stage non-small cell lung cancer: a retrospective cohort study. ( Chon, JY; Hong, JH; Hong, SH; Hwang, W; Kim, S; Kwon, H; Lee, SW; Moon, MH; Seo, KH, 2023) |
| "Propofol-based TIVA was associated with a better prognosis in comparison to INHA in patients with surgically resected pathological stage I NSCLC." | 1.62 | Prognostic significance of propofol-based intravenous anesthesia in early-stage lung cancer surgery. ( Endoh, M; Hayasaka, K; Miyata, S; Okada, Y; Shiono, S; Takaoka, S, 2021) |
| "Propofol is an anesthetic drug frequently used during tumor resection." | 1.56 | Propofol suppresses the progression of non‑small cell lung cancer via downregulation of the miR‑21‑5p/MAPK10 axis. ( Li, X; Wu, X; Xu, G, 2020) |
| "Propofol is a common sedative-hypnotic drug traditionally used for inducing and maintaining general anesthesia." | 1.56 | Propofol Affects Non-Small-Cell Lung Cancer Cell Biology By Regulating the miR-21/PTEN/AKT Pathway In Vitro and In Vivo. ( Dong, L; Ge, X; Li, Q; Li, R; Liu, D; Wang, G; Zhao, S; Zheng, X; Zhu, X, 2020) |
| "Propofol treatment inhibited viability and induced apoptosis of A549 cells in a dose-dependent manner in vitro." | 1.48 | Propofol induces apoptosis of non-small cell lung cancer cells via ERK1/2-dependent upregulation of PUMA. ( Luan, Q; Qu, JH; Ren, YD; Xing, SG; Zhang, KJ, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 7 (58.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ling, Q | 1 |
| Wu, S | 1 |
| Liao, X | 1 |
| Liu, C | 1 |
| Chen, Y | 1 |
| Han, B | 3 |
| Liu, Y | 3 |
| Zhang, Q | 3 |
| Liang, L | 3 |
| Seo, KH | 1 |
| Hong, JH | 1 |
| Moon, MH | 1 |
| Hwang, W | 1 |
| Lee, SW | 1 |
| Chon, JY | 1 |
| Kwon, H | 1 |
| Hong, SH | 1 |
| Kim, S | 1 |
| Zhang, X | 1 |
| Liu, D | 2 |
| Wang, P | 1 |
| Liu, N | 1 |
| Wu, X | 1 |
| Li, X | 1 |
| Xu, G | 1 |
| Zheng, X | 1 |
| Dong, L | 1 |
| Zhao, S | 1 |
| Li, Q | 1 |
| Zhu, X | 1 |
| Ge, X | 1 |
| Li, R | 1 |
| Wang, G | 1 |
| Hayasaka, K | 1 |
| Shiono, S | 1 |
| Miyata, S | 1 |
| Takaoka, S | 1 |
| Endoh, M | 1 |
| Okada, Y | 1 |
| Yang, N | 1 |
| Liang, Y | 1 |
| Yang, P | 1 |
| Ji, F | 1 |
| Xing, SG | 1 |
| Zhang, KJ | 1 |
| Qu, JH | 1 |
| Ren, YD | 1 |
| Luan, Q | 1 |
| Oh, TK | 1 |
| Kim, J | 1 |
| Han, S | 1 |
| Kim, K | 1 |
| Jheon, S | 1 |
| Ji, E | 1 |
| Li, C | 1 |
| Xu, M | 1 |
| Wu, Y | 1 |
| Li, YS | 1 |
| Huang, WQ | 1 |
| Liu, KX | 1 |
| Ren, XF | 1 |
| Li, WZ | 1 |
| Meng, FY | 1 |
| Lin, CF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Correlation Between Blood Pressure, Heart Rate and Plasma Corticotropin, Cortisol Under Surgical Skin Incision[NCT03892538] | 134 participants (Actual) | Observational | 2018-10-01 | Completed | |||
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Long-term Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT02660411] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Completed | |||
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on 5-year Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT05343260] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for propofol and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Limb remote ischemic preconditioning attenuates lung injury after pulmonary resection under propofol-remifentanil anesthesia: a randomized controlled study.
Topics: Acute Lung Injury; Aged; Analysis of Variance; Anesthesia, Intravenous; Anesthetics, Intravenous; Ca | 2014 |
Differential effects of propofol and isoflurane on the activation of T-helper cells in lung cancer patients.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Non-Small-Cell Lung; Cell | 2010 |
Differential effects of propofol and isoflurane on the activation of T-helper cells in lung cancer patients.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Non-Small-Cell Lung; Cell | 2010 |
Differential effects of propofol and isoflurane on the activation of T-helper cells in lung cancer patients.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Non-Small-Cell Lung; Cell | 2010 |
Differential effects of propofol and isoflurane on the activation of T-helper cells in lung cancer patients.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Non-Small-Cell Lung; Cell | 2010 |
10 other studies available for propofol and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Anesthetic propofol enhances cisplatin-sensitivity of non-small cell lung cancer cells through N6-methyladenosine-dependently regulating the miR-486-5p/RAP1-NF-κB axis.
Topics: Adenosine; Anesthetics; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cispla | 2022 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Propofol decreases cisplatin resistance of non-small cell lung cancer by inducing GPX4-mediated ferroptosis through the miR-744-5p/miR-615-3p axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disease Mo | 2023 |
Effect of total intravenous versus inhalation anesthesia on long-term oncological outcomes in patients undergoing curative resection for early-stage non-small cell lung cancer: a retrospective cohort study.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Non-Small-Cell | 2023 |
Propofol mediates non-small cell lung cancer growth in part by regulating circ_0003028-related mechanisms.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Humans; Lung Neoplasms; Mice | 2023 |
Propofol suppresses the progression of non‑small cell lung cancer via downregulation of the miR‑21‑5p/MAPK10 axis.
Topics: 3' Untranslated Regions; A549 Cells; Adult; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell P | 2020 |
Propofol Affects Non-Small-Cell Lung Cancer Cell Biology By Regulating the miR-21/PTEN/AKT Pathway In Vitro and In Vivo.
Topics: A549 Cells; Anesthetics, Intravenous; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Smal | 2020 |
Prognostic significance of propofol-based intravenous anesthesia in early-stage lung cancer surgery.
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Carcinoma, Non-Small-Cell Lung; Female; Human | 2021 |
Propofol suppresses LPS-induced nuclear accumulation of HIF-1α and tumor aggressiveness in non-small cell lung cancer.
Topics: A549 Cells; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; | 2017 |
Propofol induces apoptosis of non-small cell lung cancer cells via ERK1/2-dependent upregulation of PUMA.
Topics: A549 Cells; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Non-Small-Cell Lung; Humans; Lung N | 2018 |
Effect of sevoflurane-based or propofol-based anaesthesia on the incidence of postoperative acute kidney injury: A retrospective propensity score-matched analysis.
Topics: Acute Kidney Injury; Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; C | 2019 |