propofol has been researched along with Carcinoma, Hepatocellular in 23 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The Chinese and English medical databases were searched using a combination of the following search terms: "propofol", "liver cancer", "anesthesia surgery", and "ischemia reperfusion injury" in Chinese or English language, respectively." | 9.12 | A meta-analysis and systematic review of propofol on liver ischemia-reperfusion injury protection during hepatocellular carcinoma anesthesia surgery. ( Chen, C; Feng, C; Qian, D, 2021) |
| "Compared with sevoflurane anesthesia, propofol may improve postoperative Aβ-42 and Tau protein levels in patients with hepatocellular carcinoma, and ameliorate postoperative cognitive function." | 7.91 | Effect of propofol and sevoflurane anesthesia on postoperative cognitive function and levels of Aβ-42 and Tau in patients undergoing hepatectomy. ( Hou, JF; Xiao, CL, 2019) |
| "Propofol is one of the most extensively used intravenous anaesthetic agents, which has been found to improve the surgical intervention outcome of several types of cancer, including hepatocellular carcinoma (HCC)." | 7.91 | Propofol-induced miR-219-5p inhibits growth and invasion of hepatocellular carcinoma through suppression of GPC3-mediated Wnt/β-catenin signalling activation. ( Chen, X; Chen, Z; Deng, Z; Gong, T; Huang, S; Liu, M; Luo, R; Ning, X; Xu, Y; Zhou, B, 2019) |
| "Propofol anaesthesia was associated with better survival in hepatocellular carcinoma patients who underwent hepatectomy." | 7.91 | Propofol-based total intravenous anaesthesia is associated with better survival than desflurane anaesthesia in hepatectomy for hepatocellular carcinoma: a retrospective cohort study. ( Chan, SM; Huang, YH; Lai, HC; Lee, MS; Lin, C; Lin, KT; Wong, CS; Wu, ZF, 2019) |
| "We previously confirmed that propofol directly inhibited the viability, proliferation, and invasiveness of hepatocellular carcinoma cells in vitro." | 7.80 | Propofol exerts anti-hepatocellular carcinoma by microvesicle-mediated transfer of miR-142-3p from macrophage to cancer cells. ( Jin, HY; Jin, TT; Shan, WF; Wu, GQ; Xiong, XX; Zhang, J; Zhu, SM, 2014) |
| "Propofol decreases hepatocellular carcinoma cell invasiveness, which is partly due to the down-regulation of MMP-9 expression by miR-199a." | 7.79 | Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression. ( Feng, ZY; Wu, GQ; Zhang, D; Zhang, J; Zhu, SM, 2013) |
| "The preparation and characterization of a novel escheriosomal nanoparticle formulation of a potent anticancer conjugate, 2,6-diisopropylphenol-linoleic acid (2,6P-LA), and evaluation of its anticancer efficacy against diethyl nitrosamine-induced hepatocellular carcinoma (HCC) in BALB/c mice." | 7.79 | Anticancer efficacy of a novel propofol-linoleic acid-loaded escheriosomal formulation against murine hepatocellular carcinoma. ( Jabeen, M; Khan, AA; Owais, M, 2013) |
| "Propofol could inhibit cell proliferation, migration, and invasion and induce apoptosis via suppression on SHH to inactivate the SHH pathway." | 5.91 | Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway. ( Lai, S; Liu, Y; Wang, W; Wu, J; Wu, T; Yang, L; Zhou, F, 2023) |
| "Propofol can increase the activity and content of transforming growth factor-β1 by 12% and 20%, respectively, and then inhibit the proliferation rate of liver cancer cells by 10% through the Smad2 signaling pathway, and exponentially increase the apoptotic number of liver cancer cells." | 5.62 | The effect of propofol on the proliferation and apoptosis of hepatocellular carcinoma cells through TGF-Β1/Smad2 signaling pathway. ( Li, Z; Liu, H; Tan, H; Zhang, Y, 2021) |
| "Propofol is an intravenous anesthetic extensively used in clinical." | 5.56 | Propofol exerts anticancer activity on hepatocellular carcinoma cells by raising lncRNA DGCR5. ( Sun, H; Sun, Y, 2020) |
| "When propofol was used as the main general anesthetic agent for laparoscopic hepatic resection, the postoperative 2-year recurrence rate decreased in early- and intermediate-stage HCC." | 5.56 | Retrospective Comparison between the Effects of Propofol and Inhalation Anesthetics on Postoperative Recurrence of Early- and Intermediate-Stage Hepatocellular Carcinoma. ( Koo, BW; Lim, DJ; Na, HS; Oh, AY, 2020) |
| "Propofol is a commonly used drug for the induction and maintenance of anesthesia." | 5.56 | Propofol‑induced HOXA11‑AS promotes proliferation, migration and invasion, but inhibits apoptosis in hepatocellular carcinoma cells by targeting miR‑4458. ( Feng, Y; Jin, Y; Liu, J; Song, F, 2020) |
| "Propofol treatment downregulated the protein levels of Vimentin, MMP-2, and MMP-9 while increasing that of E-cadherin." | 5.51 | Propofol inhibits proliferation, migration, and invasion of hepatocellular carcinoma cells by downregulating Twist. ( Fu, Y; Yang, T; Zheng, H, 2019) |
| "The effects of Propofol on hepatocellular carcinoma (HCC) growth inhibition and apoptosis have been examined." | 5.39 | Propofol induces apoptosis of hepatocellular carcinoma cells by upregulation of microRNA-199a expression. ( Feng, ZY; Wu, GQ; Zhang, J; Zhang, Y; Zhu, SM, 2013) |
| "The Chinese and English medical databases were searched using a combination of the following search terms: "propofol", "liver cancer", "anesthesia surgery", and "ischemia reperfusion injury" in Chinese or English language, respectively." | 5.12 | A meta-analysis and systematic review of propofol on liver ischemia-reperfusion injury protection during hepatocellular carcinoma anesthesia surgery. ( Chen, C; Feng, C; Qian, D, 2021) |
| "Propofol has been previously demonstrated to relieve hepatocellular carcinoma (HCC)." | 4.02 | Propofol Ameliorates the Proliferation and Epithelial-Mesenchymal Transition of Hepatoma Carcinoma Cells via Non-Coding RNA Activated by DNA Damage (NORAD)/microRNA (miR)-556-3p/Migration and Invasion Enhancer 1 (MIEN1) Axis. ( Guan, E; Li, H; Liu, Y; Luo, K; Wang, X, 2021) |
| "Compared with sevoflurane anesthesia, propofol may improve postoperative Aβ-42 and Tau protein levels in patients with hepatocellular carcinoma, and ameliorate postoperative cognitive function." | 3.91 | Effect of propofol and sevoflurane anesthesia on postoperative cognitive function and levels of Aβ-42 and Tau in patients undergoing hepatectomy. ( Hou, JF; Xiao, CL, 2019) |
| "Propofol is one of the most extensively used intravenous anaesthetic agents, which has been found to improve the surgical intervention outcome of several types of cancer, including hepatocellular carcinoma (HCC)." | 3.91 | Propofol-induced miR-219-5p inhibits growth and invasion of hepatocellular carcinoma through suppression of GPC3-mediated Wnt/β-catenin signalling activation. ( Chen, X; Chen, Z; Deng, Z; Gong, T; Huang, S; Liu, M; Luo, R; Ning, X; Xu, Y; Zhou, B, 2019) |
| "Propofol anaesthesia was associated with better survival in hepatocellular carcinoma patients who underwent hepatectomy." | 3.91 | Propofol-based total intravenous anaesthesia is associated with better survival than desflurane anaesthesia in hepatectomy for hepatocellular carcinoma: a retrospective cohort study. ( Chan, SM; Huang, YH; Lai, HC; Lee, MS; Lin, C; Lin, KT; Wong, CS; Wu, ZF, 2019) |
| "We previously confirmed that propofol directly inhibited the viability, proliferation, and invasiveness of hepatocellular carcinoma cells in vitro." | 3.80 | Propofol exerts anti-hepatocellular carcinoma by microvesicle-mediated transfer of miR-142-3p from macrophage to cancer cells. ( Jin, HY; Jin, TT; Shan, WF; Wu, GQ; Xiong, XX; Zhang, J; Zhu, SM, 2014) |
| "Propofol decreases hepatocellular carcinoma cell invasiveness, which is partly due to the down-regulation of MMP-9 expression by miR-199a." | 3.79 | Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression. ( Feng, ZY; Wu, GQ; Zhang, D; Zhang, J; Zhu, SM, 2013) |
| "The preparation and characterization of a novel escheriosomal nanoparticle formulation of a potent anticancer conjugate, 2,6-diisopropylphenol-linoleic acid (2,6P-LA), and evaluation of its anticancer efficacy against diethyl nitrosamine-induced hepatocellular carcinoma (HCC) in BALB/c mice." | 3.79 | Anticancer efficacy of a novel propofol-linoleic acid-loaded escheriosomal formulation against murine hepatocellular carcinoma. ( Jabeen, M; Khan, AA; Owais, M, 2013) |
| "Propofol could inhibit cell proliferation, migration, and invasion and induce apoptosis via suppression on SHH to inactivate the SHH pathway." | 1.91 | Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway. ( Lai, S; Liu, Y; Wang, W; Wu, J; Wu, T; Yang, L; Zhou, F, 2023) |
| "Propofol can increase the activity and content of transforming growth factor-β1 by 12% and 20%, respectively, and then inhibit the proliferation rate of liver cancer cells by 10% through the Smad2 signaling pathway, and exponentially increase the apoptotic number of liver cancer cells." | 1.62 | The effect of propofol on the proliferation and apoptosis of hepatocellular carcinoma cells through TGF-Β1/Smad2 signaling pathway. ( Li, Z; Liu, H; Tan, H; Zhang, Y, 2021) |
| "Propofol is an intravenous anesthetic extensively used in clinical." | 1.56 | Propofol exerts anticancer activity on hepatocellular carcinoma cells by raising lncRNA DGCR5. ( Sun, H; Sun, Y, 2020) |
| "When propofol was used as the main general anesthetic agent for laparoscopic hepatic resection, the postoperative 2-year recurrence rate decreased in early- and intermediate-stage HCC." | 1.56 | Retrospective Comparison between the Effects of Propofol and Inhalation Anesthetics on Postoperative Recurrence of Early- and Intermediate-Stage Hepatocellular Carcinoma. ( Koo, BW; Lim, DJ; Na, HS; Oh, AY, 2020) |
| "Propofol is a commonly used drug for the induction and maintenance of anesthesia." | 1.56 | Propofol‑induced HOXA11‑AS promotes proliferation, migration and invasion, but inhibits apoptosis in hepatocellular carcinoma cells by targeting miR‑4458. ( Feng, Y; Jin, Y; Liu, J; Song, F, 2020) |
| "Propofol treatment downregulated the protein levels of Vimentin, MMP-2, and MMP-9 while increasing that of E-cadherin." | 1.51 | Propofol inhibits proliferation, migration, and invasion of hepatocellular carcinoma cells by downregulating Twist. ( Fu, Y; Yang, T; Zheng, H, 2019) |
| "Propofol is a commonly used anaesthetic with controversial effects on cancer cells." | 1.48 | Propofol Inhibits Proliferation, Migration, Invasion and Promotes Apoptosis Through Down-Regulating miR-374a in Hepatocarcinoma Cell Lines. ( Hu, ZH; Li, Y; Li, ZW; Liu, SQ; Liu, Z; Zhang, JL, 2018) |
| "The effects of Propofol on hepatocellular carcinoma (HCC) growth inhibition and apoptosis have been examined." | 1.39 | Propofol induces apoptosis of hepatocellular carcinoma cells by upregulation of microRNA-199a expression. ( Feng, ZY; Wu, GQ; Zhang, J; Zhang, Y; Zhu, SM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 2 (8.70) | 29.6817 |
| 2010's | 11 (47.83) | 24.3611 |
| 2020's | 9 (39.13) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Y | 3 |
| Wang, X | 1 |
| Li, H | 1 |
| Guan, E | 1 |
| Luo, K | 1 |
| Wu, J | 2 |
| Zhou, F | 2 |
| Lai, S | 2 |
| Wang, W | 2 |
| Wu, T | 2 |
| Yang, L | 2 |
| Sun, Y | 1 |
| Sun, H | 1 |
| Qi, J | 1 |
| Wu, Q | 1 |
| Zhu, X | 1 |
| Zhang, S | 1 |
| Chen, X | 2 |
| Chen, W | 1 |
| Sun, Z | 1 |
| Zhu, M | 1 |
| Miao, C | 1 |
| Koo, BW | 1 |
| Lim, DJ | 1 |
| Oh, AY | 1 |
| Na, HS | 1 |
| Fei, G | 1 |
| Cao, M | 1 |
| Ge, C | 1 |
| Cui, L | 1 |
| Song, F | 1 |
| Liu, J | 1 |
| Feng, Y | 1 |
| Jin, Y | 1 |
| Feng, C | 1 |
| Qian, D | 1 |
| Chen, C | 1 |
| Li, Z | 1 |
| Liu, H | 1 |
| Zhang, Y | 2 |
| Tan, H | 1 |
| Li, J | 1 |
| Liu, M | 2 |
| Zeng, B | 1 |
| Wang, Z | 1 |
| Liu, SQ | 1 |
| Zhang, JL | 1 |
| Li, ZW | 1 |
| Hu, ZH | 1 |
| Liu, Z | 1 |
| Li, Y | 2 |
| Hou, JF | 1 |
| Xiao, CL | 1 |
| Zheng, H | 1 |
| Fu, Y | 1 |
| Yang, T | 1 |
| Gong, T | 1 |
| Ning, X | 1 |
| Deng, Z | 1 |
| Zhou, B | 1 |
| Huang, S | 1 |
| Xu, Y | 1 |
| Chen, Z | 1 |
| Luo, R | 1 |
| Lai, HC | 1 |
| Lee, MS | 1 |
| Lin, C | 1 |
| Lin, KT | 1 |
| Huang, YH | 1 |
| Wong, CS | 1 |
| Chan, SM | 1 |
| Wu, ZF | 1 |
| Zhang, J | 3 |
| Zhang, D | 1 |
| Wu, GQ | 3 |
| Feng, ZY | 2 |
| Zhu, SM | 3 |
| Shan, WF | 1 |
| Jin, TT | 1 |
| Xiong, XX | 1 |
| Jin, HY | 1 |
| Lu, L | 1 |
| Zhou, J | 1 |
| Shi, J | 1 |
| Peng, XJ | 1 |
| Qi, XX | 1 |
| Wang, Y | 1 |
| Li, FY | 1 |
| Zhou, FY | 1 |
| Liu, L | 1 |
| Liu, ZQ | 1 |
| Khan, AA | 2 |
| Jabeen, M | 1 |
| Owais, M | 1 |
| Huang, W | 1 |
| Long, YH | 1 |
| Li, W | 1 |
| Wang, J | 1 |
| Chen, MS | 1 |
| Xu, MX | 1 |
| Figiel, M | 1 |
| Allritz, C | 1 |
| Lehmann, C | 1 |
| Engele, J | 1 |
| Dougherty, TB | 1 |
| Mikolajek, JA | 1 |
| Curley, SA | 1 |
1 review available for propofol and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
A meta-analysis and systematic review of propofol on liver ischemia-reperfusion injury protection during hepatocellular carcinoma anesthesia surgery.
Topics: Anesthesia; Carcinoma, Hepatocellular; China; Humans; Liver; Liver Neoplasms; Propofol; Reperfusion | 2021 |
2 trials available for propofol and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
[Application of total intravenous anesthesia with remifentanyl and propofol to radiofrequency ablation].
Topics: Anesthesia Recovery Period; Anesthetics, Intravenous; Blood Pressure; Carbon Dioxide; Carcinoma, Hep | 2007 |
Safe anesthetic management of patients undergoing a novel method of treating human hepatocellular cancer.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Alfentanil; Anesthesia, Intravenous; Anesthetics, Intravenou | 1997 |
20 other studies available for propofol and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Propofol Ameliorates the Proliferation and Epithelial-Mesenchymal Transition of Hepatoma Carcinoma Cells via Non-Coding RNA Activated by DNA Damage (NORAD)/microRNA (miR)-556-3p/Migration and Invasion Enhancer 1 (MIEN1) Axis.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Proliferation; DNA Damage; Epithelial-Mesench | 2021 |
Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Hedgehog Proteins; Humans; Liver Ne | 2023 |
Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Hedgehog Proteins; Humans; Liver Ne | 2023 |
Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Hedgehog Proteins; Humans; Liver Ne | 2023 |
Propofol Inhibits Biological Function of Hepatocellular Carcinoma Cells through LINC00475-Mediated Sonic Hedgehog Pathway.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Hedgehog Proteins; Humans; Liver Ne | 2023 |
Propofol exerts anticancer activity on hepatocellular carcinoma cells by raising lncRNA DGCR5.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expr | 2020 |
Propofol attenuates the adhesion of tumor and endothelial cells through inhibiting glycolysis in human umbilical vein endothelial cells.
Topics: Calcium-Calmodulin-Dependent Protein Kinase Type 2; Carcinoma, Hepatocellular; Cell Adhesion; Cell A | 2019 |
Retrospective Comparison between the Effects of Propofol and Inhalation Anesthetics on Postoperative Recurrence of Early- and Intermediate-Stage Hepatocellular Carcinoma.
Topics: Aged; Anesthetics; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Hepatocellular; Fem | 2020 |
Propofol suppresses hepatocellular carcinoma by inhibiting NET1 through downregulating ERK/VEGF signaling pathway.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Down-Regulation; Drug Screening Assays, | 2020 |
Propofol‑induced HOXA11‑AS promotes proliferation, migration and invasion, but inhibits apoptosis in hepatocellular carcinoma cells by targeting miR‑4458.
Topics: Anesthetics, Intravenous; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Prol | 2020 |
The effect of propofol on the proliferation and apoptosis of hepatocellular carcinoma cells through TGF-Β1/Smad2 signaling pathway.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Female; Hep G2 Cells; Humans; Liv | 2021 |
Propofol induces hepatocellular carcinoma cell apoptosis via regulating miR-105/JAK2/STAT3 axis.
Topics: Apoptosis; Base Sequence; Carcinoma, Hepatocellular; Cell Line, Tumor; Gene Expression Regulation, N | 2021 |
Propofol Inhibits Proliferation, Migration, Invasion and Promotes Apoptosis Through Down-Regulating miR-374a in Hepatocarcinoma Cell Lines.
Topics: 3' Untranslated Regions; Antagomirs; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Movement; | 2018 |
Effect of propofol and sevoflurane anesthesia on postoperative cognitive function and levels of Aβ-42 and Tau in patients undergoing hepatectomy.
Topics: Adult; Amyloid beta-Peptides; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcino | 2019 |
Propofol inhibits proliferation, migration, and invasion of hepatocellular carcinoma cells by downregulating Twist.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relati | 2019 |
Propofol-induced miR-219-5p inhibits growth and invasion of hepatocellular carcinoma through suppression of GPC3-mediated Wnt/β-catenin signalling activation.
Topics: Anesthetics, Intravenous; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell | 2019 |
Propofol-based total intravenous anaesthesia is associated with better survival than desflurane anaesthesia in hepatectomy for hepatocellular carcinoma: a retrospective cohort study.
Topics: Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Hepatocellula | 2019 |
Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression.
Topics: Anesthetics, Intravenous; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Dose-Response Rel | 2013 |
Propofol exerts anti-hepatocellular carcinoma by microvesicle-mediated transfer of miR-142-3p from macrophage to cancer cells.
Topics: Animals; Antineoplastic Agents; Biological Transport; Carcinoma, Hepatocellular; Cell Line, Tumor; C | 2014 |
Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients.
Topics: Adult; Camptothecin; Carcinoma, Hepatocellular; Genistein; Glucuronosyltransferase; Humans; Inactiva | 2015 |
Anticancer efficacy of a novel propofol-linoleic acid-loaded escheriosomal formulation against murine hepatocellular carcinoma.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; DNA Fragmentation; Humans; Linoleic Acid; | 2013 |
Propofol induces apoptosis of hepatocellular carcinoma cells by upregulation of microRNA-199a expression.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 8; Caspase 9; Drug Screening As | 2013 |
Gap junctional control of glial glutamate transporter expression.
Topics: Animals; Anticonvulsants; Carcinoma, Hepatocellular; Cell Line, Tumor; Cells, Cultured; Connexin 43; | 2007 |