propofol has been researched along with Cancer of Mouth in 12 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty patients, after trauma or major surgery with no intracranial pathology, were randomized to receive either remifentanil/propofol (n=10) or sufentanil/propofol (n=10)." | 2.70 | Recovery after remifentanil and sufentanil for analgesia and sedation of mechanically ventilated patients after trauma or major surgery. ( Biedler, A; Molter, GP; Schöpflin, I; Silomon, M; Soltész, S, 2001) |
| "5‑fluorouracil (5‑FU) is a commonly used treatment for OSCC, but cells typically display resistance to the drug." | 1.72 | Propofol induces apoptosis and ameliorates 5‑fluorouracil resistance in OSCC cells by reducing the expression and secretion of amphiregulin. ( Che, PC; Chen, JC; Chen, MS; Hsieh, MJ; Lee, IN; Wu, YP; Yang, KS, 2022) |
| "Propofol treatment inhibited cell proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT), but promoted apoptosis and induced cell cycle arrest in OSCC cells." | 1.72 | Propofol prevents the aggressive progression of oral squamous cell carcinoma via regulating circ_0005623/miR-195-5p/HOXB7 axis. ( Cao, C; Xu, Y; Zhang, X, 2022) |
| "Propofol treatment significantly promoted cell migration and invasion of OSCC." | 1.56 | Propofol facilitates migration and invasion of oral squamous cell carcinoma cells by upregulating SNAI1 expression. ( Jiang, H; Li, C; Li, W; Peng, J; Wang, H; Xia, M, 2020) |
| " The dosage of propofol recommended in these guidelines is, however, based on one single study." | 1.39 | [Palliative sedation in a man with oral cancer; the Royal Dutch Medical Association guidelines not always sufficient]. ( Broekhoff, FJ; Dompeling, EC; Smelt, WL; Vos-Westerman, JH; Wulffraat, ET, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 4 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, KS | 1 |
| Che, PC | 1 |
| Hsieh, MJ | 1 |
| Lee, IN | 1 |
| Wu, YP | 1 |
| Chen, MS | 1 |
| Chen, JC | 1 |
| Miao, L | 1 |
| Lv, X | 1 |
| Huang, C | 1 |
| Li, P | 1 |
| Sun, Y | 1 |
| Jiang, H | 2 |
| Gao, C | 1 |
| Ren, C | 1 |
| Liu, Z | 1 |
| Zhang, L | 1 |
| Tang, R | 1 |
| Li, X | 1 |
| Li, C | 1 |
| Xia, M | 1 |
| Wang, H | 1 |
| Li, W | 1 |
| Peng, J | 1 |
| Cao, C | 1 |
| Zhang, X | 1 |
| Xu, Y | 1 |
| Smelt, WL | 1 |
| Wulffraat, ET | 1 |
| Broekhoff, FJ | 1 |
| Dompeling, EC | 1 |
| Vos-Westerman, JH | 1 |
| Sasao-Takano, M | 1 |
| Misumi, K | 1 |
| Suzuki, M | 1 |
| Kamiya, Y | 1 |
| Noguchi, I | 1 |
| Kawahara, H | 1 |
| Kido, H | 1 |
| Komasawa, N | 1 |
| Ishio, J | 1 |
| Minami, T | 1 |
| Ohno, S | 1 |
| Kobayashi, K | 1 |
| Uchida, S | 1 |
| Amano, O | 1 |
| Sakagami, H | 1 |
| Nagasaka, H | 1 |
| Kunimatsu, T | 1 |
| Misaki, T | 1 |
| Hirose, N | 1 |
| Tsuboi, E | 1 |
| Takahashi, I | 1 |
| Ohki, H | 1 |
| Oi, Y | 1 |
| Matsumoto, M | 1 |
| Tanaka, H | 1 |
| Ruppen, W | 1 |
| Ruesch, S | 1 |
| Shüpfer, G | 1 |
| Christen, P | 1 |
| Soltész, S | 1 |
| Biedler, A | 1 |
| Silomon, M | 1 |
| Schöpflin, I | 1 |
| Molter, GP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| the Research of Analgesia and Sedation Effect of Remifentanil on ICU Short Operation[NCT02635802] | Phase 4 | 1,500 participants (Anticipated) | Interventional | 2015-12-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for propofol and Cancer of Mouth
| Article | Year |
|---|---|
Long-term oncological outcomes after oral cancer surgery using propofol-based total intravenous anesthesia versus sevoflurane-based inhalation anesthesia: A retrospective cohort study.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2022 |
1 trial available for propofol and Cancer of Mouth
| Article | Year |
|---|---|
Recovery after remifentanil and sufentanil for analgesia and sedation of mechanically ventilated patients after trauma or major surgery.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Combine | 2001 |
10 other studies available for propofol and Cancer of Mouth
| Article | Year |
|---|---|
Propofol induces apoptosis and ameliorates 5‑fluorouracil resistance in OSCC cells by reducing the expression and secretion of amphiregulin.
Topics: Amphiregulin; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Squamous Cell; Cell Proliferati | 2022 |
GAS5, a FoxO1-actived long noncoding RNA, promotes propofol-induced oral squamous cell carcinoma apoptosis by regulating the miR-1297-GSK3β axis.
Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Pr | 2019 |
Propofol facilitates migration and invasion of oral squamous cell carcinoma cells by upregulating SNAI1 expression.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Movement; Cell Proliferation; Gene Expression Regulation, | 2020 |
Propofol prevents the aggressive progression of oral squamous cell carcinoma via regulating circ_0005623/miR-195-5p/HOXB7 axis.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Head and Neck Neoplasms; Homeodomain Proteins; Humans; M | 2022 |
[Palliative sedation in a man with oral cancer; the Royal Dutch Medical Association guidelines not always sufficient].
Topics: Carcinoma, Squamous Cell; Conscious Sedation; Humans; Hypnotics and Sedatives; Male; Midazolam; Midd | 2013 |
Propofol drip infusion anesthesia for MRI scanning: two case reports.
Topics: Adolescent; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure Monitors; Capnography; | 2013 |
Use of a modified McGRATH MAC and tracheal tube introducer for difficult nasal intubation.
Topics: Aged; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Fentanyl; Humans; Intubation, Int | 2016 |
Cytotoxicity and type of cell death induced by midazolam in human oral normal and tumor cells.
Topics: Anesthetics, Intravenous; Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Diazepam; DNA Frag | 2012 |
Postoperative mental disorder following prolonged oral surgery.
Topics: Age Factors; Anesthetics, Intravenous; Blood Loss, Surgical; Carcinoma, Squamous Cell; Delirium; Fem | 2004 |
Propofol and questionable lack of sedation.
Topics: Alfentanil; Anesthetics, Intravenous; Atracurium; Blood Pressure; Carcinoma; Conscious Sedation; Dos | 2005 |