propofol has been researched along with Cancer of Cervix in 9 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol is a drug with potential anticancer effect." | 1.91 | The effect of propofol on chemosensitivity of paclitaxel in cervical cancer cells. ( Chen, M; Jin, Y; Sheng, B; Xie, S; Zhu, X, 2023) |
| "Cervical cancer is the most prevalent malignancy worldwide and propofol reportedly has anti-cancer efficiencies." | 1.62 | Propofol suppresses the growth and invasion of cervical carcinoma cells by inhibiting MIR155HG. ( Du, XT; Liu, DP; Wang, XY; Zheng, YH, 2021) |
| "STAT3 was over-expressed in cervical cancer cells by STAT3 cDNA." | 1.46 | Propofol enhances the cisplatin-induced apoptosis on cervical cancer cells via EGFR/JAK2/STAT3 pathway. ( Chen, J; Cheng, X; Li, H; Li, M; Lu, Y; Pang, Y, 2017) |
| "Propofol has been proposed to play a role of antitumor in various cancers." | 1.42 | Propofol promotes cell apoptosis via inhibiting HOTAIR mediated mTOR pathway in cervical cancer. ( Qian, JH; Wu, GQ; Ying, J; Zhang, D; Zhang, J; Zhou, XH; Zhou, YX, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Du, XT | 1 |
| Wang, XY | 1 |
| Zheng, YH | 1 |
| Liu, DP | 1 |
| Jin, Y | 1 |
| Xie, S | 1 |
| Sheng, B | 1 |
| Chen, M | 1 |
| Zhu, X | 1 |
| Rezniczek, GA | 1 |
| Hecken, JM | 1 |
| Rehman, S | 1 |
| Dogan, A | 1 |
| Tempfer, CB | 1 |
| Hilal, Z | 1 |
| Ghai, B | 1 |
| Jain, K | 1 |
| Bansal, D | 1 |
| Wig, J | 1 |
| Zhang, D | 1 |
| Zhou, XH | 1 |
| Zhang, J | 1 |
| Zhou, YX | 1 |
| Ying, J | 1 |
| Wu, GQ | 1 |
| Qian, JH | 1 |
| Zhang, F | 1 |
| Wang, C | 1 |
| Cui, Y | 1 |
| Li, S | 1 |
| Yao, Y | 1 |
| Ci, Y | 1 |
| Wang, J | 1 |
| Hou, W | 1 |
| Wu, A | 1 |
| Li, E | 1 |
| Liu, S | 1 |
| Gu, X | 1 |
| Zhu, L | 1 |
| Wu, G | 1 |
| Zhou, H | 1 |
| Song, Y | 1 |
| Wu, C | 1 |
| Li, H | 1 |
| Lu, Y | 1 |
| Pang, Y | 1 |
| Li, M | 1 |
| Cheng, X | 1 |
| Chen, J | 1 |
| Oei-Lim, VL | 1 |
| Kalkman, CJ | 1 |
| van Tienhoven, G | 1 |
| Engbers, FH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Large Loop Excision of the Transformation Zone (LLETZ) With Versus Without Intraoperative Application of Lugol's Iodine in Women With Cervical Dysplasia: a Prospective Randomized Trial[NCT05132114] | 216 participants (Anticipated) | Interventional | 2022-01-17 | Recruiting | |||
| Large Loop Excision of the Transformatione Zone Under General Versus Local Anesthesia: a Randomized Trial.[NCT03494686] | 229 participants (Actual) | Interventional | 2018-04-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for propofol and Cancer of Cervix
| Article | Year |
|---|---|
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes | 2020 |
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes | 2020 |
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes | 2020 |
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes | 2020 |
End-tidal concentrations of sevoflurane and desflurane for ProSeal laryngeal mask airway removal in anaesthetised adults: a randomised double-blind study.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Desflurane; Device Re | 2014 |
Effects of propofol and sevoflurane on perioperative immune response in patients undergoing laparoscopic radical hysterectomy for cervical cancer.
Topics: Adenocarcinoma; Anesthetics, Inhalation; Anesthetics, Intravenous; Carcinoma, Squamous Cell; CD4-CD8 | 2016 |
6 other studies available for propofol and Cancer of Cervix
| Article | Year |
|---|---|
Propofol suppresses the growth and invasion of cervical carcinoma cells by inhibiting MIR155HG.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; | 2021 |
The effect of propofol on chemosensitivity of paclitaxel in cervical cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Female; Humans; Paclitaxel; Propofol; Stathmin; Tub | 2023 |
Propofol promotes cell apoptosis via inhibiting HOTAIR mediated mTOR pathway in cervical cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Female; HeLa Cells; Huma | 2015 |
Effects of Propofol on Several Membrane Characteristics of Cervical Cancer Cell Lines.
Topics: Cell Membrane; Cell Movement; Cell Proliferation; Cell Shape; Cytoskeleton; Female; HeLa Cells; Huma | 2016 |
Propofol enhances the cisplatin-induced apoptosis on cervical cancer cells via EGFR/JAK2/STAT3 pathway.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Synergism; ErbB R | 2017 |
Remote controlled prolonged conscious sedation for gynaecological radiotherapy.
Topics: Anesthetics, Intravenous; Brachytherapy; Carbon Dioxide; Conscious Sedation; Drug Administration Sch | 1996 |