propofol has been researched along with Brugada ECG Pattern in 22 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this prospective, double-blinded trial, 98 patients with established Brugada syndrome were randomized to receive propofol (2 to 3 mg/kg) or etomidate (0." | 9.34 | Electrocardiographic Effects of Propofol versus Etomidate in Patients with Brugada Syndrome. ( Beckers, S; Bhutia, JT; Brugada, P; Carvalho, H; Chierchia, GB; Cools, W; de Asmundis, C; Dewals, W; Flamée, P; Forget, P; Poelaert, J; Umbrain, V; Varnavas, V; Verborgh, C, 2020) |
| "This anesthetic drug may cause a rare condition named propofol infusion syndrome, characterized by unexplained lactic acidosis, lipemia, rhabdomyolysis, cardiovascular collapse and Brugada-like electrocardiographic pattern or Brugada electrocardiographic phenocopy changes following high-dose propofol infusion over prolonged periods of time." | 8.86 | Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy. ( Dubner, S; Ferreira, C; Filho, CF; Riera, AR; Schapachnik, E; Uchida, AH, 2010) |
| "Propofol administration in patients with Brugada syndrome (BrS) is still a matter of debate." | 8.02 | Propofol for Induction and Maintenance of Anesthesia in Patients With Brugada Syndrome: A Single-Center, 25-Year, Retrospective Cohort Analysis. ( de Asmundis, C; Flamée, P; Forget, P; Nogueira Carvalho, H; Poelaert, J; Tosi, M; Viaene, K, 2021) |
| "Avoiding propofol in patients with Brugada syndrome has been suggested because of the theoretical risk of provoking ventricular arrhythmias, although propofol may be selected for conscious sedation during electrophysiological procedures in catheterization laboratories." | 7.88 | Propofol for implantable cardioverter defibrillator implantation in patients with Brugada syndrome. ( Kim, SH; Kim, WJ; Kwon, HM; Nam, GB; Park, HS; Park, SU; Rhim, JH, 2018) |
| " A patient with complicated malaria in whom Brugada-ECG abnormalities appeared in concomitance with fever and propofol administration is presented." | 7.79 | Brugada ECG disclosed by acute malaria: is it all about fever and propofol? ( El Maghawry, M; Meggiolaro, M; Migliore, F; Peruzza, F; Pittoni, GM; Zorzi, A, 2013) |
| "We report a case of a young man with paroxysmal atrial fibrillation, in whom a characteristic coved-type Brugada pattern developed during catheter ablation performed under sedation with propofol." | 7.78 | Propofol-induced coved-type electrocardiogram during catheter ablation of paroxysmal atrial fibrillation. A case of Brugada syndrome? ( Brugada, P; Richter, S, 2012) |
| "Propofol is an anesthetic drug with a very attractive pharmacokinetic profile, which makes it the induction agent of choice, especially in day-case surgery." | 5.39 | Safe single-dose administration of propofol in patients with established Brugada syndrome: a retrospective database analysis. ( Beckers, S; Bhutia, JT; Brugada, P; Casado-Arroyo, R; Chierchia, GB; Conte, G; De Asmundis, C; Flamée, P; Poelaert, J; Sarkozy, A; Umbrain, V; Van Malderen, S; Verborgh, C, 2013) |
| "In this prospective, double-blinded trial, 98 patients with established Brugada syndrome were randomized to receive propofol (2 to 3 mg/kg) or etomidate (0." | 5.34 | Electrocardiographic Effects of Propofol versus Etomidate in Patients with Brugada Syndrome. ( Beckers, S; Bhutia, JT; Brugada, P; Carvalho, H; Chierchia, GB; Cools, W; de Asmundis, C; Dewals, W; Flamée, P; Forget, P; Poelaert, J; Umbrain, V; Varnavas, V; Verborgh, C, 2020) |
| "This anesthetic drug may cause a rare condition named propofol infusion syndrome, characterized by unexplained lactic acidosis, lipemia, rhabdomyolysis, cardiovascular collapse and Brugada-like electrocardiographic pattern or Brugada electrocardiographic phenocopy changes following high-dose propofol infusion over prolonged periods of time." | 4.86 | Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy. ( Dubner, S; Ferreira, C; Filho, CF; Riera, AR; Schapachnik, E; Uchida, AH, 2010) |
| "Propofol administration in patients with Brugada syndrome (BrS) is still a matter of debate." | 4.02 | Propofol for Induction and Maintenance of Anesthesia in Patients With Brugada Syndrome: A Single-Center, 25-Year, Retrospective Cohort Analysis. ( de Asmundis, C; Flamée, P; Forget, P; Nogueira Carvalho, H; Poelaert, J; Tosi, M; Viaene, K, 2021) |
| "Avoiding propofol in patients with Brugada syndrome has been suggested because of the theoretical risk of provoking ventricular arrhythmias, although propofol may be selected for conscious sedation during electrophysiological procedures in catheterization laboratories." | 3.88 | Propofol for implantable cardioverter defibrillator implantation in patients with Brugada syndrome. ( Kim, SH; Kim, WJ; Kwon, HM; Nam, GB; Park, HS; Park, SU; Rhim, JH, 2018) |
| " A patient with complicated malaria in whom Brugada-ECG abnormalities appeared in concomitance with fever and propofol administration is presented." | 3.79 | Brugada ECG disclosed by acute malaria: is it all about fever and propofol? ( El Maghawry, M; Meggiolaro, M; Migliore, F; Peruzza, F; Pittoni, GM; Zorzi, A, 2013) |
| "We report a case of a young man with paroxysmal atrial fibrillation, in whom a characteristic coved-type Brugada pattern developed during catheter ablation performed under sedation with propofol." | 3.78 | Propofol-induced coved-type electrocardiogram during catheter ablation of paroxysmal atrial fibrillation. A case of Brugada syndrome? ( Brugada, P; Richter, S, 2012) |
| " Recently, there have been reports of Brugada ECG patterns seen in critically ill patients who received propofol,(1) and this pattern was associated with a very high imminent mortality." | 3.76 | Recovery following propofol-associated brugada electrocardiogram. ( Haddad, EV; Raj, SR; Weiner, JB, 2010) |
| "Propofol is an anesthetic drug with a very attractive pharmacokinetic profile, which makes it the induction agent of choice, especially in day-case surgery." | 1.39 | Safe single-dose administration of propofol in patients with established Brugada syndrome: a retrospective database analysis. ( Beckers, S; Bhutia, JT; Brugada, P; Casado-Arroyo, R; Chierchia, GB; Conte, G; De Asmundis, C; Flamée, P; Poelaert, J; Sarkozy, A; Umbrain, V; Van Malderen, S; Verborgh, C, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 11 (50.00) | 24.3611 |
| 2020's | 5 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Flamée, P | 5 |
| Varnavas, V | 1 |
| Dewals, W | 3 |
| Carvalho, H | 1 |
| Cools, W | 1 |
| Bhutia, JT | 2 |
| Beckers, S | 2 |
| Umbrain, V | 2 |
| Verborgh, C | 2 |
| Forget, P | 3 |
| Chierchia, GB | 2 |
| Brugada, P | 4 |
| Poelaert, J | 4 |
| de Asmundis, C | 3 |
| Uzun, D | 1 |
| Hassan, N | 1 |
| Kohli, U | 2 |
| Viaene, K | 1 |
| Tosi, M | 1 |
| Nogueira Carvalho, H | 1 |
| Kwon, HM | 1 |
| Kim, SH | 1 |
| Park, SU | 1 |
| Rhim, JH | 1 |
| Park, HS | 1 |
| Kim, WJ | 1 |
| Nam, GB | 1 |
| Paramythiotou, E | 1 |
| Ntai, K | 1 |
| Dimopoulos, G | 1 |
| Armaganidis, A | 1 |
| Ciconte, G | 1 |
| Santinelli, V | 1 |
| Brugada, J | 2 |
| Vicedomini, G | 1 |
| Conti, M | 1 |
| Monasky, MM | 1 |
| Borrelli, V | 1 |
| Castracane, W | 1 |
| Aloisio, T | 1 |
| Giannelli, L | 1 |
| Di Dedda, U | 1 |
| Pozzi, P | 1 |
| Ranucci, M | 1 |
| Pappone, C | 1 |
| Conte, G | 1 |
| Van Malderen, S | 1 |
| Casado-Arroyo, R | 1 |
| Sarkozy, A | 2 |
| Meggiolaro, M | 1 |
| Zorzi, A | 1 |
| El Maghawry, M | 1 |
| Peruzza, F | 1 |
| Migliore, F | 1 |
| Pittoni, GM | 1 |
| Duque, M | 1 |
| Santos, L | 1 |
| Ribeiro, S | 1 |
| Catré, D | 1 |
| Robinson, JD | 1 |
| Melman, Y | 1 |
| Walsh, EP | 1 |
| Bebarta, VS | 2 |
| Summers, S | 2 |
| Behr, ER | 1 |
| Camm, AJ | 1 |
| Riezzo, I | 1 |
| Centini, F | 1 |
| Neri, M | 1 |
| Rossi, G | 1 |
| Spanoudaki, E | 1 |
| Turillazzi, E | 1 |
| Fineschi, V | 1 |
| Weiner, JB | 1 |
| Haddad, EV | 1 |
| Raj, SR | 1 |
| Riera, AR | 1 |
| Uchida, AH | 1 |
| Schapachnik, E | 1 |
| Dubner, S | 1 |
| Filho, CF | 1 |
| Ferreira, C | 1 |
| Faulkner, MJ | 1 |
| Haley, MW | 1 |
| Littmann, L | 1 |
| Richter, S | 1 |
| Junttila, MJ | 1 |
| Gonzalez, M | 1 |
| Lizotte, E | 1 |
| Benito, B | 1 |
| Vernooy, K | 1 |
| Huikuri, HV | 1 |
| Brugada, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Epicardial Ablation in 500 Consecutive Brugada Syndrome Patients[NCT03106701] | 300 participants (Anticipated) | Interventional | 2017-03-14 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for propofol and Brugada ECG Pattern
| Article | Year |
|---|---|
Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy.
Topics: Acidosis, Lactic; Anesthetics, Intravenous; Animals; Brugada Syndrome; Electrocardiography; Heart Co | 2010 |
Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias.
Topics: Adult; Age of Onset; Anesthetics; Antidepressive Agents, Tricyclic; Brugada Syndrome; Cocaine; Death | 2008 |
2 trials available for propofol and Brugada ECG Pattern
| Article | Year |
|---|---|
Electrocardiographic Effects of Propofol versus Etomidate in Patients with Brugada Syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Intravenous; Brugada S | 2020 |
General Anesthesia Attenuates Brugada Syndrome Phenotype Expression: Clinical Implications From a Prospective Clinical Trial.
Topics: Adult; Anesthesia, General; Anesthetics, General; Brugada Syndrome; Electrocardiography; Female; Hum | 2018 |
18 other studies available for propofol and Brugada ECG Pattern
| Article | Year |
|---|---|
Post-operative Brugada electrocardiographic pattern, polymorphic ventricular tachycardia, and sudden death in a child after administration of propofol anaesthesia.
Topics: Adenoidectomy; Anesthetics, Intravenous; Brugada Syndrome; Child; Death, Sudden, Cardiac; Desmoplaki | 2020 |
A fatal adverse event upon adenotonsillectomy in a child. Are Brugada syndrome and propofol real accomplices?
Topics: Anesthesia; Brugada Syndrome; Child; Death, Sudden; Humans; Propofol; Tachycardia, Ventricular | 2020 |
Reply to letter "A fatal adverse event upon adenotonsillectomy in a child. Are Brugada syndrome and propofol real accomplices?"
Topics: Arrhythmias, Cardiac; Brugada Syndrome; Child; Humans; Propofol; Ventricular Fibrillation | 2020 |
Propofol for Induction and Maintenance of Anesthesia in Patients With Brugada Syndrome: A Single-Center, 25-Year, Retrospective Cohort Analysis.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Brugada Syndrome; Cohort Studies; Female; | 2021 |
Propofol for implantable cardioverter defibrillator implantation in patients with Brugada syndrome.
Topics: Adjuvants, Anesthesia; Adult; Brugada Syndrome; Conscious Sedation; Defibrillators, Implantable; Fem | 2018 |
Propofol associated Brugada - like coved type electrogardiogram in a trauma patient with a fatal outcome.
Topics: Accidents, Traffic; Adult; Brain Injuries, Traumatic; Brugada Syndrome; Electrocardiography; Fatal O | 2019 |
Safe single-dose administration of propofol in patients with established Brugada syndrome: a retrospective database analysis.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Brugada Syndrome; Child; Databases, Factual; Dose-Res | 2013 |
Brugada ECG disclosed by acute malaria: is it all about fever and propofol?
Topics: Brugada Syndrome; Electrocardiography; Humans; Hypnotics and Sedatives; Malaria; Malaria, Cerebral; | 2013 |
Uneventful prolonged propofol infusion in a patient with Brugada syndrome.
Topics: Anesthetics, Intravenous; Brugada Syndrome; Female; Humans; Propofol; Time Factors; Young Adult | 2017 |
Anesthesia and Brugada syndrome: a 12-year case series.
Topics: Adult; Aged; Analgesics, Opioid; Anesthesia; Anesthetics; Anesthetics, Intravenous; Brugada Syndrome | 2017 |
Cardiac conduction disturbances and ventricular tachycardia after prolonged propofol infusion in an infant.
Topics: Anesthetics, Intravenous; Brugada Syndrome; Diagnosis, Differential; Humans; Infant; Infusions, Intr | 2008 |
Propofol-induced Brugada electrocardiographic pattern.
Topics: Anesthetics, Intravenous; Brugada Syndrome; Critical Care; Drug Monitoring; Electrocardiography; Hum | 2008 |
Letter by Behr and Camm regarding article, "Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias".
Topics: Adult; Age of Onset; Anesthetics; Antidepressive Agents, Tricyclic; Brugada Syndrome; Cocaine; Death | 2008 |
Predictor of mortality in suspected propofol infusion syndrome--Brugada electrocardiographic pattern.
Topics: Anesthetics, Intravenous; Brugada Syndrome; Hospital Mortality; Humans; Predictive Value of Tests; P | 2009 |
Brugada-like EKG pattern and myocardial effects in a chronic propofol abuser.
Topics: Adult; Anesthetics, Intravenous; Brugada Syndrome; Death, Sudden, Cardiac; Electrocardiography; Fata | 2009 |
Recovery following propofol-associated brugada electrocardiogram.
Topics: Alprazolam; Brugada Syndrome; Humans; Hypnotics and Sedatives; Male; Propofol; Tramadol; Treatment O | 2010 |
Propofol infusion syndrome with severe and dynamic Brugada electrocardiogram but benign clinical outcome.
Topics: Brugada Syndrome; Electrocardiography, Ambulatory; Humans; Infusions, Intravenous; Male; Propofol; S | 2011 |
Propofol-induced coved-type electrocardiogram during catheter ablation of paroxysmal atrial fibrillation. A case of Brugada syndrome?
Topics: Adult; Anesthetics, Intravenous; Atrial Fibrillation; Brugada Syndrome; Catheter Ablation; Electroen | 2012 |