propofol has been researched along with Brain Injuries, Traumatic in 14 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Brain Injuries, Traumatic: A form of acquired brain injury which occurs when a sudden trauma causes damage to the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol is a commonly used intravenous anesthetic." | 5.62 | Propofol maintains Th17/Treg cell balance and reduces inflammation in rats with traumatic brain injury via the miR‑145‑3p/NFATc2/NF‑κB axis. ( Cai, Y; Chen, J; Cui, C; Guo, Y; Hu, J; Li, H; Lin, G; Nong, L; Sun, K; Sun, Y; Wang, P; Xu, L; Yang, W; Yu, D; Zhang, D, 2021) |
| " Propofol, a lipid-soluble intravenous anesthetic, has been shown to possess therapeutic benefit during neuroinflammation on various brain injury models." | 3.83 | Propofol Inhibits NLRP3 Inflammasome and Attenuates Blast-Induced Traumatic Brain Injury in Rats. ( Fan, K; Gu, J; Hou, J; Ma, J; Ren, J; Wang, J; Wu, J; Xiao, W; Yu, B, 2016) |
| "Propofol is a commonly used intravenous anesthetic." | 1.62 | Propofol maintains Th17/Treg cell balance and reduces inflammation in rats with traumatic brain injury via the miR‑145‑3p/NFATc2/NF‑κB axis. ( Cai, Y; Chen, J; Cui, C; Guo, Y; Hu, J; Li, H; Lin, G; Nong, L; Sun, K; Sun, Y; Wang, P; Xu, L; Yang, W; Yu, D; Zhang, D, 2021) |
| "Propofol was commonly used and is potentially associated with poorer clinical outcomes." | 1.56 | Comparison of drugs used for intubation of pediatric trauma patients. ( Davidson, J; Merritt, N; Mudri, M; Priestap, F; Williams, A, 2020) |
| "Sedation therapy is vital for treating severe traumatic brain injury (TBI)." | 1.48 | The Influence of Sedation Level Guided by Bispectral Index on Therapeutic Effects for Patients with Severe Traumatic Brain Injury. ( Gao, H; Gong, K; Na, H; Pang, L; Ruan, S; Wu, W; Xu, W; Yan, K; Zhang, H; Zhen, Y; Zhou, X, 2018) |
| "Propofol treatment could elicit a robust neuroprotective response, resulting in significant neurological function improvement for TBI rats, which was independent with intralipid." | 1.43 | Propofol administration improves neurological function associated with inhibition of pro-inflammatory cytokines in adult rats after traumatic brain injury. ( Chen, MR; Liu, F; Liu, J; Wang, TH; Wang, TY; Zou, Y; Zuo, YX, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 10 (71.43) | 2.80 |
| Authors | Studies |
|---|---|
| Jeffcote, T | 1 |
| Weir, T | 1 |
| Anstey, J | 1 |
| Mcnamara, R | 1 |
| Bellomo, R | 1 |
| Udy, A | 1 |
| Wu, B | 1 |
| Song, WQ | 1 |
| Dong, JQ | 1 |
| Yue, HL | 1 |
| Lu, Y | 1 |
| Yu, Y | 1 |
| Hao, SY | 1 |
| Liu, BY | 1 |
| Cui, WH | 1 |
| Maheswari, N | 1 |
| Panda, NB | 1 |
| Mahajan, S | 1 |
| Luthra, A | 1 |
| Pattnaik, S | 1 |
| Bhatia, N | 1 |
| Karthigeyan, M | 1 |
| Kaloria, N | 1 |
| Chauhan, R | 1 |
| Soni, S | 1 |
| Jangra, K | 1 |
| Bhagat, H | 1 |
| Dolmans, RGF | 1 |
| Nahed, BV | 1 |
| Robertson, FC | 1 |
| Peul, WC | 1 |
| Rosenthal, ES | 1 |
| Broekman, MLD | 1 |
| Huang, YQ | 1 |
| Weiss, S | 1 |
| Gros, P | 1 |
| Wong, E | 1 |
| Piché, PP | 1 |
| Vyas, MV | 1 |
| Tam, AKH | 1 |
| Watt, JA | 1 |
| Hausburg, MA | 1 |
| Banton, KL | 1 |
| Roman, PE | 1 |
| Salgado, F | 1 |
| Baek, P | 1 |
| Waxman, MJ | 1 |
| Tanner, A | 1 |
| Yoder, J | 1 |
| Bar-Or, D | 1 |
| Mudri, M | 1 |
| Williams, A | 1 |
| Priestap, F | 1 |
| Davidson, J | 1 |
| Merritt, N | 1 |
| Dauwe, DF | 1 |
| Gunst, J | 1 |
| Vlasselaers, D | 1 |
| Meyfroidt, G | 1 |
| Cui, C | 1 |
| Zhang, D | 1 |
| Sun, K | 1 |
| Li, H | 1 |
| Xu, L | 1 |
| Lin, G | 1 |
| Guo, Y | 1 |
| Hu, J | 1 |
| Chen, J | 1 |
| Nong, L | 1 |
| Cai, Y | 1 |
| Yu, D | 1 |
| Yang, W | 1 |
| Wang, P | 1 |
| Sun, Y | 1 |
| Spindler, LRB | 1 |
| Luppi, AI | 1 |
| Adapa, RM | 1 |
| Craig, MM | 1 |
| Coppola, P | 1 |
| Peattie, ARD | 1 |
| Manktelow, AE | 1 |
| Finoia, P | 1 |
| Sahakian, BJ | 1 |
| Williams, GB | 1 |
| Allanson, J | 1 |
| Pickard, JD | 1 |
| Menon, DK | 1 |
| Stamatakis, EA | 1 |
| Yan, K | 1 |
| Pang, L | 1 |
| Gao, H | 1 |
| Zhang, H | 1 |
| Zhen, Y | 1 |
| Ruan, S | 1 |
| Wu, W | 1 |
| Xu, W | 1 |
| Gong, K | 1 |
| Zhou, X | 1 |
| Na, H | 1 |
| Paramythiotou, E | 1 |
| Ntai, K | 1 |
| Dimopoulos, G | 1 |
| Armaganidis, A | 1 |
| Liu, F | 1 |
| Chen, MR | 1 |
| Liu, J | 1 |
| Zou, Y | 1 |
| Wang, TY | 1 |
| Zuo, YX | 1 |
| Wang, TH | 1 |
| Ma, J | 1 |
| Xiao, W | 1 |
| Wang, J | 1 |
| Wu, J | 1 |
| Ren, J | 1 |
| Hou, J | 1 |
| Gu, J | 1 |
| Fan, K | 1 |
| Yu, B | 1 |
3 reviews available for propofol and Brain Injuries, Traumatic
| Article | Year |
|---|---|
The Impact of Sedative Choice on Intracranial and Systemic Physiology in Moderate to Severe Traumatic Brain Injury: A Scoping Review.
Topics: Adult; Analgesics, Opioid; Brain Injuries; Brain Injuries, Traumatic; Dexmedetomidine; Humans; Hypno | 2023 |
Prevention and treatment of traumatic brain injury-related delirium: a systematic review.
Topics: Adult; Aged; Brain Injuries, Traumatic; Delirium; Haloperidol; Humans; Middle Aged; Propofol | 2023 |
Effects of propofol on ischemia-reperfusion and traumatic brain injury.
Topics: Anesthesia; Anesthetics; Animals; Apoptosis; Astrocytes; Brain; Brain Injuries, Traumatic; Disease M | 2020 |
1 trial available for propofol and Brain Injuries, Traumatic
| Article | Year |
|---|---|
Ketofol as an Anesthetic Agent in Patients With Isolated Moderate to Severe Traumatic Brain Injury: A Prospective, Randomized Double-blind Controlled Trial.
Topics: Anesthetics, Intravenous; Brain Injuries, Traumatic; Glial Fibrillary Acidic Protein; Humans; Ketami | 2023 |
10 other studies available for propofol and Brain Injuries, Traumatic
| Article | Year |
|---|---|
Effects of Sevoflurane and Propofol on Neurological Recovery of Traumatic Brain Injury Patients in the Early Postoperative Stage: A Retrospective Cohort Study.
Topics: Brain Injuries, Traumatic; Decompressive Craniectomy; Humans; Propofol; Retrospective Studies; Sevof | 2023 |
Practice-Pattern Variation in Sedation of Neurotrauma Patients in the Intensive Care Unit: An International Survey.
Topics: Brain Injuries, Traumatic; Critical Care; Humans; Hypnotics and Sedatives; Intensive Care Units; Pro | 2023 |
Comparison of drugs used for intubation of pediatric trauma patients.
Topics: Adolescent; Brain Injuries, Traumatic; Child; Child, Preschool; Etomidate; Female; Hospitals, Pediat | 2020 |
Propofol-infusion syndrome in traumatic brain injury: consider the ECMO option.
Topics: Anesthetics, Intravenous; Brain Injuries, Traumatic; Extracorporeal Membrane Oxygenation; Humans; Pr | 2021 |
Propofol maintains Th17/Treg cell balance and reduces inflammation in rats with traumatic brain injury via the miR‑145‑3p/NFATc2/NF‑κB axis.
Topics: Animals; Brain Injuries, Traumatic; Inflammation; Male; MicroRNAs; NF-kappa B; NFATC Transcription F | 2021 |
Dopaminergic brainstem disconnection is common to pharmacological and pathological consciousness perturbation.
Topics: Adolescent; Adult; Aged; Brain Injuries, Traumatic; Brain Stem; Case-Control Studies; Connectome; Co | 2021 |
The Influence of Sedation Level Guided by Bispectral Index on Therapeutic Effects for Patients with Severe Traumatic Brain Injury.
Topics: Adult; Brain; Brain Injuries, Traumatic; Conscious Sedation; Consciousness Monitors; Deep Sedation; | 2018 |
Propofol associated Brugada - like coved type electrogardiogram in a trauma patient with a fatal outcome.
Topics: Accidents, Traffic; Adult; Brain Injuries, Traumatic; Brugada Syndrome; Electrocardiography; Fatal O | 2019 |
Propofol administration improves neurological function associated with inhibition of pro-inflammatory cytokines in adult rats after traumatic brain injury.
Topics: Animals; Behavior, Animal; Brain Injuries, Traumatic; Cytokines; Disease Models, Animal; Encephaliti | 2016 |
Propofol Inhibits NLRP3 Inflammasome and Attenuates Blast-Induced Traumatic Brain Injury in Rats.
Topics: Animals; Brain Injuries, Traumatic; Cerebral Cortex; Cytokines; Inflammasomes; Inflammation; NLR Fam | 2016 |