propofol has been researched along with Brain Infarction in 3 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol is an intravenous anesthetic that is commonly used during intravascular embolectomy following acute ischemic stroke." | 5.56 | Propofol Attenuates α-Synuclein Aggregation and Neuronal Damage in a Mouse Model of Ischemic Stroke. ( Cui, V; Tian, D; Wang, H; Wang, Y; Wei, C; Wu, A; Yue, Y; Zhu, Y, 2020) |
| "Rats underwent 2 h of middle cerebral artery occlusion (MCAO) followed by 22 h of reperfusion were randomly divided into nine groups (n=15 each): sham-operated group, MCAO group, propofol 10, 20 and 35 mg x kg(-1) x h(-1) group (propofol 10, 20, 35 mg x kg(-1) x h(-1) infused at the onset of reperfusion for 30 min), wortmannin group (wortmannin 0." | 5.35 | The role of phosphoinositide-3-kinase/Akt pathway in propofol-induced postconditioning against focal cerebral ischemia-reperfusion injury in rats. ( Wang, GL; Wang, HY; Wang, Y; Yu, YH, 2009) |
| "Propofol is an intravenous anesthetic that is commonly used during intravascular embolectomy following acute ischemic stroke." | 1.56 | Propofol Attenuates α-Synuclein Aggregation and Neuronal Damage in a Mouse Model of Ischemic Stroke. ( Cui, V; Tian, D; Wang, H; Wang, Y; Wei, C; Wu, A; Yue, Y; Zhu, Y, 2020) |
| "Rats underwent 2 h of middle cerebral artery occlusion (MCAO) followed by 22 h of reperfusion were randomly divided into nine groups (n=15 each): sham-operated group, MCAO group, propofol 10, 20 and 35 mg x kg(-1) x h(-1) group (propofol 10, 20, 35 mg x kg(-1) x h(-1) infused at the onset of reperfusion for 30 min), wortmannin group (wortmannin 0." | 1.35 | The role of phosphoinositide-3-kinase/Akt pathway in propofol-induced postconditioning against focal cerebral ischemia-reperfusion injury in rats. ( Wang, GL; Wang, HY; Wang, Y; Yu, YH, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 2 |
| Tian, D | 1 |
| Wei, C | 1 |
| Cui, V | 1 |
| Wang, H | 1 |
| Zhu, Y | 1 |
| Wu, A | 1 |
| Yue, Y | 1 |
| Yu, H | 1 |
| Wang, X | 1 |
| Kang, F | 1 |
| Chen, Z | 1 |
| Meng, Y | 1 |
| Dai, M | 1 |
| Wang, HY | 1 |
| Wang, GL | 1 |
| Yu, YH | 1 |
3 other studies available for propofol and Brain Infarction
| Article | Year |
|---|---|
Propofol Attenuates α-Synuclein Aggregation and Neuronal Damage in a Mouse Model of Ischemic Stroke.
Topics: alpha-Synuclein; Animals; Behavior, Animal; Brain Infarction; Brain Ischemia; Disease Models, Animal | 2020 |
Propofol attenuates inflammatory damage on neurons following cerebral infarction by inhibiting excessive activation of microglia.
Topics: Actins; Animals; Brain Infarction; Cell Death; Cell Movement; Cell Proliferation; Cytoskeleton; Dise | 2019 |
The role of phosphoinositide-3-kinase/Akt pathway in propofol-induced postconditioning against focal cerebral ischemia-reperfusion injury in rats.
Topics: Androstadienes; Animals; Brain; Brain Infarction; Disease Models, Animal; Dose-Response Relationship | 2009 |