Page last updated: 2024-11-03

propofol and Brain Damage, Chronic

propofol has been researched along with Brain Damage, Chronic in 6 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Brain Damage, Chronic: A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.

Research Excerpts

ExcerptRelevanceReference
"This study compares the effects of propofol and fentanyl/N2O on spontaneous brain electrical activity, neurologic outcome, and neuronal damage due to incomplete cerebral ischemia in rats."3.68The effects of propofol on brain electrical activity, neurologic outcome, and neuronal damage following incomplete ischemia in rats. ( Albrecht, RF; Hoffman, WE; Kochs, E; Schulte am Esch, J; Thomas, C; Werner, C, 1992)
"Outcome prediction is more difficult in comatose survivors of cardiac arrest who are treated with hypothermia than in those who are kept normothermic."2.48Prognosis of coma after cardiac arrest in the era of hypothermia. ( De Georgia, M; Raad, B, 2012)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, B1
Liang, G1
Khojasteh, S1
Wu, Z1
Yang, W1
Joseph, D1
Wei, H1
Klimathianaki, M1
Kondili, E1
Alexopoulou, C1
Prinianakis, G1
Georgopoulos, D1
De Georgia, M1
Raad, B1
Jevtović-Todorović, V1
Kirby, CO1
Olney, JW1
Kochs, E1
Hoffman, WE1
Werner, C1
Thomas, C1
Albrecht, RF1
Schulte am Esch, J1

Reviews

1 review available for propofol and Brain Damage, Chronic

ArticleYear
Prognosis of coma after cardiac arrest in the era of hypothermia.
    Continuum (Minneapolis, Minn.), 2012, Volume: 18, Issue:3

    Topics: Animals; Biomarkers; Brain Damage, Chronic; Clinical Trials as Topic; Coma; Combined Modality Therap

2012

Trials

1 trial available for propofol and Brain Damage, Chronic

ArticleYear
Effect of propofol on breathing stability in adult ICU patients with brain damage.
    Respiratory physiology & neurobiology, 2010, May-31, Volume: 171, Issue:3

    Topics: Adolescent; Adult; Aged; Brain Damage, Chronic; Brain Injuries; Female; Humans; Hypnotics and Sedati

2010

Other Studies

4 other studies available for propofol and Brain Damage, Chronic

ArticleYear
Comparison of neurodegeneration and cognitive impairment in neonatal mice exposed to propofol or isoflurane.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Administration, Inhalation; Anesthetics; Animals; Animals, Newborn; Apoptosis; Brain Damage, Chronic

2014
Pediatric emergency medicine: legal briefs.
    Pediatric emergency care, 2007, Volume: 23, Issue:3

    Topics: Acidosis; Administration, Cutaneous; Adult; Asphyxia; Brain Damage, Chronic; Burns, Chemical; Child;

2007
Isoflurane and propofol block neurotoxicity caused by MK-801 in the rat posterior cingulate/retrosplenial cortex.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1997, Volume: 17, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Brain Damage, Chronic; Dizocilpine Maleate; Excitatory Amino Acid

1997
The effects of propofol on brain electrical activity, neurologic outcome, and neuronal damage following incomplete ischemia in rats.
    Anesthesiology, 1992, Volume: 76, Issue:2

    Topics: Animals; Brain; Brain Damage, Chronic; Brain Diseases; Brain Ischemia; Depression, Chemical; Electro

1992