Page last updated: 2024-11-03

propofol and Bone Neoplasms

propofol has been researched along with Bone Neoplasms in 7 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.

Research Excerpts

ExcerptRelevanceReference
"Propofol suppresses cell proliferation, migration and invasion of osteosarcoma cells through FOXO1/TUSC7 axis by regulating AKT/GSK3β signalling."8.02Propofol suppresses osteosarcoma cell function by regulating FOXO1/TUSC7. ( Huang, X; Liu, J; Xie, H, 2021)
"The different concentrations of propofol were co-incubated with osteosarcoma MG-63 lines for 72 hrs."7.83Propofol suppresses invasion and induces apoptosis of osteosarcoma cell in vitro via downregulation of TGF-β1 expression. ( Du, QH; Guo, XG; Jiang, W; Li, G; Xu, YB; Zhang, MY; Zhao, FR, 2016)
"Propofol suppresses cell proliferation, migration and invasion of osteosarcoma cells through FOXO1/TUSC7 axis by regulating AKT/GSK3β signalling."4.02Propofol suppresses osteosarcoma cell function by regulating FOXO1/TUSC7. ( Huang, X; Liu, J; Xie, H, 2021)
"The different concentrations of propofol were co-incubated with osteosarcoma MG-63 lines for 72 hrs."3.83Propofol suppresses invasion and induces apoptosis of osteosarcoma cell in vitro via downregulation of TGF-β1 expression. ( Du, QH; Guo, XG; Jiang, W; Li, G; Xu, YB; Zhang, MY; Zhao, FR, 2016)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Huang, X1
Liu, J1
Xie, H1
Ye, Z1
Jingzhong, L1
Yangbo, L1
Lei, C1
Jiandong, Y1
Xu, YB1
Jiang, W1
Zhao, FR1
Li, G1
Du, QH1
Zhang, MY1
Guo, XG1
Mammoto, T2
Mukai, M1
Mammoto, A1
Yamanaka, Y1
Hayashi, Y1
Mashimo, T1
Kishi, Y2
Nakamura, H1
Baba, M1
Nakagawa, M1
Kuri, M1
Taniguchi, H1
Kanbara, N1
Sakai, T1
Ivani, G1
Mossetti, V1
Andreacchio, A1
Scher, CS1
Amar, D1
McDowall, RH1
Barst, SM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Randomized, Controlled Trial to Compare the Effect of TIVA Propofol vs Sevoflurane Anaesthetic on Serumserum Biomarkers and on PBMCs in Patients Undergoing Breast Cancer Resection Surgery[NCT03005860]0 participants (Actual)Interventional2017-01-01Withdrawn (stopped due to Funding could not be arranged, so the study was prematurely terminated)
A Randomized, Open-label Study to Compare Propofol Anesthesia With Sevoflurane Anesthesia in Terms of Overall Survival in Patients With Surgical Intervention for Either Breast-, Colon- or Rectal Cancer[NCT01975064]Phase 45,774 participants (Actual)Interventional2013-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for propofol and Bone Neoplasms

ArticleYear
Propofol suppresses osteosarcoma cell function by regulating FOXO1/TUSC7.
    The Journal of pharmacy and pharmacology, 2021, Apr-27, Volume: 73, Issue:6

    Topics: Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Forkhead Box Protein O1; Glycog

2021
Propofol inhibits proliferation and invasion of osteosarcoma cells by regulation of microRNA-143 expression.
    Oncology research, 2013, Volume: 21, Issue:4

    Topics: Anesthetics, Intravenous; Apoptosis; Bone Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell S

2013
Propofol suppresses invasion and induces apoptosis of osteosarcoma cell in vitro via downregulation of TGF-β1 expression.
    European review for medical and pharmacological sciences, 2016, Volume: 20, Issue:7

    Topics: Apoptosis; Blotting, Western; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; C

2016
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
    Cancer letters, 2002, Oct-28, Volume: 184, Issue:2

    Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N

2002
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
    Cancer letters, 2002, Oct-28, Volume: 184, Issue:2

    Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N

2002
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
    Cancer letters, 2002, Oct-28, Volume: 184, Issue:2

    Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N

2002
Intravenous anesthetic, propofol inhibits invasion of cancer cells.
    Cancer letters, 2002, Oct-28, Volume: 184, Issue:2

    Topics: Actins; Anesthetics, Intravenous; Animals; Bone Neoplasms; Cell Adhesion; HeLa Cells; Humans; Lung N

2002
[Anesthetic management of a patient with squeezed heart by huge sternal tumor].
    Masui. The Japanese journal of anesthesiology, 2003, Volume: 52, Issue:7

    Topics: Anesthesia, Epidural; Anesthesia, General; Bone Neoplasms; Chondrosarcoma; Female; Heart Neoplasms;

2003
Ultrasound-guided peripheral catheter placement for upper limb amputation in a 12-year-old boy: possible phantom limb pain prevention?
    Paediatric anaesthesia, 2008, Volume: 18, Issue:4

    Topics: Amputation, Surgical; Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Bone Ne

2008
Use of propofol for the prevention of chemotherapy-induced nausea and emesis in oncology patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Antiemetics; Antineoplastic Agents; Bone Neoplasms; Cyclophosphamide; Female; Hum

1992