propofol has been researched along with Bleeding in 19 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Propofol-based anesthesia is favored in order to enhance TcMEP quality." | 7.88 | Changes in transcranial motor evoked potentials during hemorrhage are associated with increased serum propofol concentrations. ( Feiner, J; Jasiukaitis, P; Lieberman, JA; Lyon, R; Rollins, M, 2018) |
| "After 120 min of steady state infusion of propofol at a rate of 2 mg x kg(-1) x h(-1), nine instrumented immature swine were studied using a stepwise increasing hemorrhagic model (200 ml of blood every 30 min until 1 h, then additional stepwise bleeding of 100 ml every 30 min thereafter, to the point of circulatory collapse)." | 7.71 | Influence of hemorrhage on propofol pseudo-steady state concentration. ( Kazama, T; Kurita, T; Morita, K; Nakata, J; Sato, S, 2002) |
| "Choosing propofol over volatile anesthetics during dilatation and evacuation might reduce bleeding and the incidence of excessive bleeding." | 5.12 | Impact of anesthetic agents on the amount of bleeding during dilatation and evacuation: A systematic review and meta-analysis. ( Goto, T; Kawakami, H; Lee, HA; Mihara, T; Sato, H, 2021) |
| " Propofol-based anesthesia is favored in order to enhance TcMEP quality." | 3.88 | Changes in transcranial motor evoked potentials during hemorrhage are associated with increased serum propofol concentrations. ( Feiner, J; Jasiukaitis, P; Lieberman, JA; Lyon, R; Rollins, M, 2018) |
| "After hemorrhage, leukocyte adhesion and CD11b expression increased during thiopental anesthesia, but propofol/fentanyl and ketamine protected against hemorrhage-induced leukocyte adhesion." | 3.73 | Intravenous anesthesia inhibits leukocyte-endothelial interactions and expression of CD11b after hemorrhage. ( Brookes, ZL; Brown, NJ; Lawton, BK; Reilly, CS, 2006) |
| " The initial reaction was successfully treated with dantrolene, but during the following days the patient developed several compartment syndromes requiring fasciotomies." | 3.72 | A fatal case of malignant hyperthermia complicated by generalized compartment syndrome and rhabdomyolysis. ( Green, G, 2003) |
| "Although the plasma propofol concentration in the lactated Ringer's solution group increased with hemorrhage and infusion, it decreased in both the hydroxyethyl starch and the threefold lactated Ringer's solution groups." | 3.72 | Influence of fluid infusion associated with high-volume blood loss on plasma propofol concentrations. ( Fujii, S; Kazama, T; Kurita, T; Morita, K; Sato, S; Takata, K; Uraoka, M, 2004) |
| "After 120 min of steady state infusion of propofol at a rate of 2 mg x kg(-1) x h(-1), nine instrumented immature swine were studied using a stepwise increasing hemorrhagic model (200 ml of blood every 30 min until 1 h, then additional stepwise bleeding of 100 ml every 30 min thereafter, to the point of circulatory collapse)." | 3.71 | Influence of hemorrhage on propofol pseudo-steady state concentration. ( Kazama, T; Kurita, T; Morita, K; Nakata, J; Sato, S, 2002) |
| "We have studied in eight rabbits the cardiovascular effects of midazolam, propofol and alfentanil with graded hypoxia." | 3.69 | Haemodynamic response to simulated haemorrhage in the rabbit: interaction of i.v. anaesthesia and hypoxia. ( Blake, DW; Ludbrook, J; Petring, OU; Van Leeuwen, AF; Ventura, S, 1995) |
| "Perioperative bleeding is one of the major comorbidities associated with surgery." | 2.72 | The Role of Anesthetic Selection in Perioperative Bleeding. ( DiNardo, JA; Koutsogiannaki, S; Yuki, K, 2021) |
| "The presence of stridor after extubation, and pulse oximeter-determined arterial blood oxyhemoglobin saturation immediately after extubation and 5 minutes later, were noted." | 2.68 | Comparison of intravenous ketorolac and alfentanil as supplements to propofol anesthesia for diagnostic panendoscopy. ( Bosek, V; Endicott, J; Klotch, D; Ridley, M; Smith, DB, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 10 (52.63) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, HA | 1 |
| Kawakami, H | 1 |
| Mihara, T | 1 |
| Sato, H | 1 |
| Goto, T | 1 |
| Yuki, K | 1 |
| DiNardo, JA | 1 |
| Koutsogiannaki, S | 1 |
| Lieberman, JA | 1 |
| Feiner, J | 1 |
| Rollins, M | 1 |
| Lyon, R | 1 |
| Jasiukaitis, P | 1 |
| Ruane-O'Hora, T | 1 |
| Hall, WJ | 1 |
| Markos, F | 1 |
| Kurita, T | 3 |
| Uraoka, M | 2 |
| Morita, K | 3 |
| Suzuki, M | 1 |
| Morishima, Y | 1 |
| Sato, S | 3 |
| Kazama, T | 2 |
| Nakata, J | 1 |
| Honan, DM | 1 |
| Breen, PJ | 1 |
| Boylan, JF | 1 |
| McDonald, NJ | 1 |
| Egan, TD | 1 |
| Brookes, ZL | 3 |
| Brown, NJ | 3 |
| Reilly, CS | 3 |
| Fariña Castro, R | 1 |
| Monzón Rubio, E | 1 |
| Ojeda Betancor, N | 1 |
| Rodríguez-Pérez, A | 1 |
| Green, G | 1 |
| Fujii, S | 1 |
| Takata, K | 1 |
| Takizawa, D | 1 |
| Sato, E | 1 |
| Kurosaki, D | 1 |
| Hiraoka, H | 1 |
| Saito, S | 1 |
| Goto, F | 1 |
| Lawton, BK | 1 |
| Disma, N | 1 |
| Astuto, M | 1 |
| Giorgio, AD | 1 |
| Russo, G | 1 |
| Bosek, V | 1 |
| Smith, DB | 1 |
| Endicott, J | 1 |
| Klotch, D | 1 |
| Ridley, M | 1 |
| Blake, DW | 1 |
| Van Leeuwen, AF | 2 |
| Petring, OU | 1 |
| Ludbrook, J | 2 |
| Ventura, S | 1 |
| Evans, RG | 1 |
| Debaene, B | 1 |
| Goldfarb, G | 1 |
| Braillon, A | 1 |
| Jolis, P | 1 |
| Lebrec, D | 1 |
2 reviews available for propofol and Bleeding
| Article | Year |
|---|---|
Impact of anesthetic agents on the amount of bleeding during dilatation and evacuation: A systematic review and meta-analysis.
Topics: Abortion, Induced; Abortion, Spontaneous; Anesthetics, Inhalation; Anesthetics, Intravenous; Dilatat | 2021 |
The Role of Anesthetic Selection in Perioperative Bleeding.
Topics: Anesthesia; Anesthesiology; Anesthetics; Blood Coagulation; Desflurane; Hemorrhage; Hemostasis; Huma | 2021 |
1 trial available for propofol and Bleeding
| Article | Year |
|---|---|
Comparison of intravenous ketorolac and alfentanil as supplements to propofol anesthesia for diagnostic panendoscopy.
Topics: Alfentanil; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intravenous; Anti-Infl | 1995 |
16 other studies available for propofol and Bleeding
| Article | Year |
|---|---|
Changes in transcranial motor evoked potentials during hemorrhage are associated with increased serum propofol concentrations.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Arterial Pressure; Blood Pressure; Cardiac Output; El | 2018 |
The effect of alphaxalone-alphadolone, propofol, and pentobarbitone anaesthesia on the β-endorphin and ACTH response to haemorrhage in the pig.
Topics: Adrenocorticotropic Hormone; Anesthesia; Anesthetics; Animals; beta-Endorphin; Blood Pressure; Heart | 2011 |
Influence of haemorrhage on the pseudo-steady-state remifentanil concentration in a swine model: a comparison with propofol and the effect of haemorrhagic shock stage.
Topics: Analysis of Variance; Anesthetics, Intravenous; Animals; Blood Pressure; Blood Volume; Cardiac Outpu | 2011 |
Influence of hemorrhage on propofol pseudo-steady state concentration.
Topics: Anesthetics, Intravenous; Animals; Cardiac Output; Female; Hemodynamics; Hemorrhage; Male; Metabolic | 2002 |
Decrease in bispectral index preceding intraoperative hemodynamic crisis: evidence of acute alteration of propofol pharmacokinetics.
Topics: Aged; Anesthesia, Intravenous; Electroencephalography; Female; Hemodynamics; Hemorrhage; Humans; Int | 2002 |
Response of the rat cremaster microcirculation to hemorrhage in vivo: differential effects of intravenous anesthetic agents.
Topics: Anesthetics, Intravenous; Animals; Blood Gas Analysis; Hemodynamics; Hemorrhage; Ketamine; Male; Mic | 2002 |
[Necro-hemorrhagic pancreatitis after prolonged propofol perfusion].
Topics: Adult; Hemorrhage; Humans; Hypnotics and Sedatives; Male; Necrosis; Pancreatic Diseases; Pancreatiti | 2002 |
A fatal case of malignant hyperthermia complicated by generalized compartment syndrome and rhabdomyolysis.
Topics: Adult; Anesthetics, Intravenous; Compartment Syndromes; Dantrolene; Fatal Outcome; Hemorrhage; Human | 2003 |
Influence of fluid infusion associated with high-volume blood loss on plasma propofol concentrations.
Topics: Animals; Blood Volume; Cardiac Output; Fluid Therapy; Hemodilution; Hemorrhage; Propofol; Shock; Swi | 2004 |
Changes in unbound concentration of propofol during hemorrhage.
Topics: Anesthesia; Blood Pressure; Blood Transfusion; Dopamine; Female; Fentanyl; Heart Rate; Hemorrhage; H | 2005 |
Intravenous anesthesia inhibits leukocyte-endothelial interactions and expression of CD11b after hemorrhage.
Topics: Anesthesia, Intravenous; Animals; CD11b Antigen; Cell Adhesion; Endothelial Cells; Endothelium, Vasc | 2006 |
Scurvy: a disease of anesthetic interest? Scurvy and anesthesia.
Topics: Airway Obstruction; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Ascorbic | 2008 |
Haemodynamic response to simulated haemorrhage in the rabbit: interaction of i.v. anaesthesia and hypoxia.
Topics: Alfentanil; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Cardiac Output; Hemodynamics | 1995 |
Differential effects of intravenous anaesthetic agents on the response of rat mesenteric microcirculation in vivo after haemorrhage.
Topics: Anesthetics, Combined; Anesthetics, Intravenous; Animals; Fentanyl; Hemodynamics; Hemorrhage; Ketami | 2002 |
Effects of halothane, ketamine, propofol and alfentanil anaesthesia on circulatory control in rabbits.
Topics: Alfentanil; Anesthetics; Animals; Blood Pressure; Blood Volume; Halothane; Heart Rate; Hemorrhage; K | 1990 |
[Splanchnic hemodynamic changes caused by ketamine and propofol in the cirrhotic rat. Effects of hemorrhage].
Topics: Anesthetics; Animals; Hemorrhage; Ketamine; Liver Cirrhosis, Biliary; Propofol; Rats; Splanchnic Cir | 1989 |