propofol has been researched along with Benign Neoplasms in 81 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Based on animal data only, some clinicians have adopted propofol-based anesthesia for cancer surgery with the aim of increased survival." | 9.30 | Rationale and Design of the CAN Study: an RCT of Survival after Propofol- or Sevoflurane-based Anesthesia for Cancer Surgery. ( Bergkvist, L; Berglund, A; Enlund, A; Enlund, M, 2019) |
| "To investigate the incidence of complications related to propofol-based anesthesia and the factors associated with complications in children with radiotherapy." | 7.91 | Propofol-based balanced anesthesia is safer in pediatric radiotherapy. ( B Bay, S; I Çelik, A; Pasin, Ö; Tütüncü, AÇ; Yıldırım, İ, 2019) |
| "Propofol was infused during PVP in eleven cancer patients after obtaining written informed consent." | 5.32 | [Use of propofol for painful procedures in cancer pain management]. ( Nakaho, T; Ohara, T; Takahashi, M; Yamamoto, Y; Yamamuro, M, 2003) |
| "Based on animal data only, some clinicians have adopted propofol-based anesthesia for cancer surgery with the aim of increased survival." | 5.30 | Rationale and Design of the CAN Study: an RCT of Survival after Propofol- or Sevoflurane-based Anesthesia for Cancer Surgery. ( Bergkvist, L; Berglund, A; Enlund, A; Enlund, M, 2019) |
| "The addition of fentanyl 1 mcg/kg to propofol for brief painful procedures reduces movement, propofol dose, and recovery time." | 5.17 | Prospective randomized crossover evaluation of three anesthetic regimens for painful procedures in children with cancer. ( Anghelescu, DL; Burgoyne, LL; Faughnan, LG; Hankins, GM; Pui, CH; Smeltzer, MP, 2013) |
| "Our study showed that the use of propofol resulted in less hypertension and tachycardia at and after intubation than etomidate." | 5.17 | Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial. ( Kamenik, M; Möller Petrun, A, 2013) |
| "Between January 2019 and June 2020, English language articles on PubMed were searched for the keywords "Propofol" "TIVA" or "IV anesthesia" and either "cancer surgery" or "surgical oncology." | 5.12 | Association Between Anesthesia Delivered During Tumor Resection and Cancer Survival: a Systematic Review of a Mixed Picture with Constant Themes. ( Douin, DJ; Ejaz, A; Fernandez-Bustamante, A; Gleisner, A; Pawlik, TM; Selby, LV, 2021) |
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| " The objectives of the study were to compare postoperative complications, the overall survival, and recurrence-free survival of patients who had received volatile anesthesia against those of patients who had received propofol-based total intravenous anesthesia for digestive tract cancer curative surgeries." | 4.12 | Volatile anesthesia versus propofol-based total intravenous anesthesia: A retrospective analysis of charts of patients who underwent elective digestive tract cancer curative surgeries. ( Deng, Y; Wang, D; Wang, F; Wei, Y; Zhang, H; Zhang, Y, 2022) |
| "To investigate the incidence of complications related to propofol-based anesthesia and the factors associated with complications in children with radiotherapy." | 3.91 | Propofol-based balanced anesthesia is safer in pediatric radiotherapy. ( B Bay, S; I Çelik, A; Pasin, Ö; Tütüncü, AÇ; Yıldırım, İ, 2019) |
| "Long-term survival after major cancer surgery was similar with i." | 3.30 | Long-term survival in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: follow-up of a multicentre randomised trial. ( Ai, YQ; Cao, SJ; Guo, YQ; Jia, Z; Li, HJ; Li, XY; Liu, ZH; Ma, D; Ma, JH; Ouyang, W; Pan, LH; Sessler, DI; Sun, XD; Wang, DX; Wang, MR; Ye, QS; Yin, N; Yu, JB; Zhang, FX; Zhang, Y; Zhang, YX; Zhao, BJ; Zhao, W, 2023) |
| "With the global disease burden of cancer increasing, and with at least 60% of cancer patients requiring surgery and, hence, anaesthesia over their disease course, the question of whether anaesthetic and analgesia techniques during primary cancer resection surgery might influence long term oncological outcomes assumes high priority." | 3.01 | Anaesthetic Techniques and Strategies: Do They Influence Oncological Outcomes? ( Buggy, DJ; Murphy, L; Shaker, J, 2023) |
| "Elderly patients who have solid organ cancer often receive surgery." | 2.84 | Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial. ( Ai, YQ; Guo, YQ; Jia, HQ; Jia, Z; Li, HJ; Liu, ZH; Ma, D; Ouyang, W; Pan, LH; Sun, XD; Tan, HY; Wang, DX; Yang, XD; Ye, QS; Yin, N; Yu, JB; Zhang, FX; Zhang, QG; Zhang, Y; Zhao, BJ, 2017) |
| "Anesthetics are extensively used during cancer surgeries." | 2.72 | Targeting miRNAs with anesthetics in cancer: Current understanding and future perspectives. ( Esmailpoor, ZH; Geraylow, KR; Masrouri, S; Tabnak, P; Zarei, M, 2021) |
| "As of 2018 cancer is responsible for almost 9." | 2.72 | Anesthetics or anesthetic techniques and cancer surgical outcomes: a possible link. ( Alam, A; Hana, Z; Ma, D; Patel, S; Rampes, S, 2021) |
| "Propofol has several advantages over traditional sedating agents that would indicate its use in treatment-refractory situations." | 2.71 | When nothing helps: propofol as sedative and antiemetic in palliative cancer care. ( Fürst, CJ; Lundström, S; Zachrisson, U, 2005) |
| " bolus dosing in children undergoing ambulatory oncologic procedures in the pediatric intensive care unit (PICU)." | 2.71 | Comparison of intermittent versus continuous infusion of propofol for elective oncology procedures in children. ( Anderson, BD; Dalton, HJ; Gootenberg, JE; Hauser, GJ; Hertzog, JH; Klein, SM; Shad, AT, 2003) |
| "Midazolam is a useful drug used preoperatively because it can produce anxiolysis and sedation." | 2.70 | [Effects of midazolam premedication on induction doses of propofol and hemodynamic changes during tumor patient induction]. ( Lin, WQ; Tan, HY; Wang, J; Xu, MX; Zeng, WA, 2002) |
| "Cancer is a key cause of death worldwide." | 2.66 | The mechanism of propofol in cancer development: An updated review. ( Gao, X; Gou, X; Guo, N; Hu, Z; Luan, J; Mi, Y; Wang, N; Xu, H; Xu, L; Zhang, D, 2020) |
| "Propofol use is encouraged in cancers that appear to have a better prognosis after its use during surgery." | 2.66 | Effects of propofol on the development of cancer in humans. ( Jiang, W; Pan, S; Xu, Y; Xue, F; Zhu, X, 2020) |
| "This is especially evident where major cancer surgery was undertaken." | 2.61 | Anesthetic technique and cancer outcomes: a meta-analysis of total intravenous versus volatile anesthesia. ( Dubowitz, J; Hiller, J; Lopez-Olivo, MA; Riedel, B; Yap, A, 2019) |
| "Propofol is an ideal hypnotic for the sedation of children under spontaneous breathing for proton beam radiation therapy." | 2.48 | [Pediatric anesthesia for proton radiotherapy : medicine remote from the medical centre]. ( Ares, C; Frei-Welte, M; Mauch, J; Neuhaus, D; Weiss, M, 2012) |
| "Adult patients who underwent cancer resection surgery (breast, gastric, lung, liver, kidney, colorectal, pancreatic, esophageal, and bladder cancer) under general anesthesia between January 2007 and December 2016 were included." | 1.91 | Impact of Propofol-based Total Intravenous Anesthesia Versus Inhalation Anesthesia on Long-term Survival After Cancer Surgery in a Nationwide Cohort. ( Cho, Y; Jeon, Y; Jung, SY; Kim, MS; Yoon, D; Yoon, S, 2023) |
| "Patients aged 65-90 yr undergoing major cancer surgery were randomised to either propofol-based anaesthesia or to sevoflurane-based anaesthesia." | 1.91 | Delirium in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: a multicentre randomised trial. ( Ai, YQ; Cao, SJ; Guo, YQ; Jia, Z; Li, HJ; Li, XY; Liu, ZH; Ma, D; Ma, JH; Ouyang, W; Pan, LH; Sessler, DI; Sun, XD; Wang, DX; Wang, MR; Ye, QS; Yin, N; Yu, JB; Zhang, FX; Zhang, Y; Zhang, YX; Zhao, BJ; Zhao, W, 2023) |
| "Anaesthetics may modify colorectal cancer cell biology which potentially affects long-term survival." | 1.91 | The differential cancer growth associated with anaesthetics in a cancer xenograft model of mice: mechanisms and implications of postoperative cancer recurrence. ( Buggy, D; Hu, C; Ishikawa, M; Iwasaki, M; Ma, D; Saito, J; Sakamoto, A; Sherwin, A; Wu, L; Zhao, H, 2023) |
| "Moreover, propofol protected cancer cells from RSL3-induced ferroptosis in vitro, as evidenced by decreases in intracellular levels of reactive oxygen species (ROS), lipid peroxide, and ferroptosis markers." | 1.91 | Anesthetic propofol inhibits ferroptosis and aggravates distant cancer metastasis via Nrf2 upregulation. ( Hou, Q; Li, S; Ma, Y; Sun, L; Wang, H; Yuan, J; Zhang, B; Zhang, X; Zhao, X; Zheng, H, 2023) |
| "Propofol dose differed in cancer comparing to no cancer patients under general anaesthesia." | 1.72 | Propofol doses differ in total intravenous anaesthesia (TIVA) for cancer and no cancer surgery - observational cohort study. ( Pejakov, L; Ždralević, M; Đurišić, I, 2022) |
| "In order to investigate the effect of remifentanil combined with propofol on awakening of craniotomy for tumor, a retrospective analysis is conducted." | 1.72 | The Efficacy of Remifentanil Combined with Propofol in Craniotomy for Tumor Was Evaluated by Wake Quality, Hemodynamics, and Adverse Reactions. ( Chen, J; Han, Y; Zhou, Q, 2022) |
| "Breast cancer remains one of the most dreadful female malignancies globally, in which cancer stem cells (CSCs) play crucial functions." | 1.62 | The inhibition of circular RNA circNOLC1 by propofol/STAT3 attenuates breast cancer stem cells function via miR-365a-3p/STAT3 signaling. ( Heng, JY; Li, EY; Liu, YP; Zhao, XY, 2021) |
| "Sevoflurane anesthesia was identified as an independent risk factor for recurrence-free survival." | 1.62 | Long-term survival differences between sevoflurane and propofol use in general anesthesia for gynecologic cancer surgery. ( Amano, E; Hirao, M; Matsumoto, H; Miyo, M; Shibuya, H; Takeyama, E; Tatsumi, K, 2021) |
| "Preclinical data suggest suppression of cancer proliferation by propofol, and retrospective studies suggest improved survival after cancer surgery with propofol-based anaesthesia." | 1.56 | Association between propofol dose and 1-year mortality in patients with or without a diagnosis of solid cancer. ( Chhangani, K; Eikermann, M; Grabitz, SD; Houle, TT; Kienbaum, P; Landoni, G; O'Gara, B; Raub, D; Schaefer, MS; Shay, D; Teja, B; Xu, X, 2020) |
| "Propofol is a short-acting general anesthetic agent, widely used for induction and maintenance of general anesthesia and rarely employed in palliative care." | 1.51 | Propofol-based palliative sedation in terminally ill children with solid tumors: A case series. ( Angela, M; Annalisa, S; Cefalo, MG; De Pasquale, MD; Del Bufalo, F; Luigi, S; Miele, E; Spinelli, GP, 2019) |
| " Therefore, we investigated the factors affecting propofol dosage for pediatric patients undergoing sedation for computed tomography (CT) simulation." | 1.48 | Factors affecting propofol dosage for sedation in pediatric oncology. ( Eom, W; Kang, S; Lee, DE; Oh, TK; Park, B, 2018) |
| "Delirium was the most frequent reason for PS (n = 15, 75%)." | 1.46 | Bispectral Index monitoring in cancer patients undergoing palliative sedation: a preliminary report. ( Allende-Pérez, S; Bruera, E; García-Salamanca, MF; Hui, D; Monreal-Carrillo, E; Verástegui, E, 2017) |
| "The risk of being underweight has not been evaluated in this arena." | 1.46 | Association of BMI With Propofol Dosing and Adverse Events in Children With Cancer Undergoing Procedural Sedation. ( Abulebda, K; Hobson, MJ; Rogerson, CM, 2017) |
| "Overall, there were few SAEs, and airway obstruction was the most common SAE." | 1.43 | Complications of Deep Sedation for Individual Procedures (Lumbar Puncture Alone) Versus Combined Procedures (Lumbar Puncture and Bone Marrow Aspirate) in Pediatric Oncology Patients. ( Kamat, PP; McCracken, CE; Patel, MM; Simon, HK, 2016) |
| " However, the toxic effect was higher in the high density culture." | 1.43 | Propofol depresses cisplatin cytotoxicity via the inhibition of gap junctions. ( Ge, H; Tao, L; Wang, Q; Wang, X; Zhang, Y, 2016) |
| " The modification of propofol dosage in the group of patients under study is not necessary when TCI-guided administration of propofol by means of the Schnider model is used." | 1.42 | Pharmacokinetics and pharmacodynamics of propofol in cancer patients undergoing major lung surgery. ( Bienert, A; Grześkowiak, E; Kaliszan, R; Kut, K; Plenzler, E; Przybyłowski, K; Szczesny, D; Tyczka, J; Wiczling, P, 2015) |
| "Ninety cancer patients with selective operation from March 2011 to May 2014 were randomly divided into group A (34 cases), group B (28 cases) and group C (28 cases)." | 1.40 | Influence of propofol, isoflurane and enflurance on levels of serum interleukin-8 and interleukin-10 in cancer patients. ( Liu, TC, 2014) |
| "Propofol infusions were continued until the time of death." | 1.38 | Pediatric palliative sedation therapy with propofol: recommendations based on experience in children with terminal cancer. ( Anghelescu, DL; Baker, JN; Faughnan, LG; Hamilton, H; Johnson, LM, 2012) |
| "This process has been shown to ablate tumors in animal studies." | 1.36 | Irreversible electroporation: a new challenge in "out of operating theater" anesthesia. ( Ball, C; Kavnoudias, H; Thomson, KR, 2010) |
| "Propofol was infused during PVP in eleven cancer patients after obtaining written informed consent." | 1.32 | [Use of propofol for painful procedures in cancer pain management]. ( Nakaho, T; Ohara, T; Takahashi, M; Yamamoto, Y; Yamamuro, M, 2003) |
| "Propofol was associated with faster onset, better recovery, early oral feeding time, no nausea and vomiting and better parental acceptability." | 1.31 | Propofol for pediatric radiotherapy. ( Bhatnagar, S; Kannan, TR; Mishra, S; Pandey, V; Panigrahi, M; Punj, J; Saxena, A, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (7.41) | 18.2507 |
| 2000's | 14 (17.28) | 29.6817 |
| 2010's | 32 (39.51) | 24.3611 |
| 2020's | 29 (35.80) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Khan, AA | 1 |
| Alam, M | 1 |
| Tufail, S | 1 |
| Mustafa, J | 1 |
| Owais, M | 1 |
| Tabnak, P | 1 |
| Masrouri, S | 1 |
| Geraylow, KR | 1 |
| Zarei, M | 1 |
| Esmailpoor, ZH | 1 |
| Liu, YP | 1 |
| Heng, JY | 1 |
| Zhao, XY | 1 |
| Li, EY | 1 |
| Wu, H | 1 |
| Xin, L | 1 |
| Lin, JH | 1 |
| Wang, QH | 1 |
| Li, B | 1 |
| Jin, ZD | 1 |
| Hu, LH | 1 |
| Zou, WB | 1 |
| Qi, K | 1 |
| Yang, T | 1 |
| Li, ZS | 1 |
| Liao, Z | 1 |
| Yoon, S | 1 |
| Jung, SY | 1 |
| Kim, MS | 1 |
| Yoon, D | 1 |
| Cho, Y | 1 |
| Jeon, Y | 1 |
| Zhang, Y | 6 |
| Wang, F | 1 |
| Zhang, H | 1 |
| Wei, Y | 1 |
| Deng, Y | 1 |
| Wang, D | 1 |
| Zhou, Q | 1 |
| Han, Y | 1 |
| Chen, J | 2 |
| Cuviello, A | 1 |
| Pasli, M | 1 |
| Bhatia, S | 1 |
| Johnson, LM | 2 |
| Anghelescu, DL | 4 |
| Baker, JN | 2 |
| Iwasaki, M | 1 |
| Zhao, H | 1 |
| Hu, C | 1 |
| Saito, J | 1 |
| Wu, L | 1 |
| Sherwin, A | 1 |
| Ishikawa, M | 1 |
| Sakamoto, A | 1 |
| Buggy, D | 2 |
| Ma, D | 7 |
| Pejakov, L | 1 |
| Ždralević, M | 1 |
| Đurišić, I | 1 |
| Bonvini, JM | 1 |
| Zhang, B | 1 |
| Hou, Q | 1 |
| Zhang, X | 1 |
| Ma, Y | 1 |
| Yuan, J | 1 |
| Li, S | 1 |
| Zhao, X | 1 |
| Sun, L | 1 |
| Wang, H | 1 |
| Zheng, H | 1 |
| Mincer, JS | 1 |
| Buggy, DJ | 2 |
| Cata, JP | 2 |
| Murphy, L | 1 |
| Shaker, J | 1 |
| Cao, SJ | 3 |
| Zhang, YX | 3 |
| Zhao, W | 2 |
| Pan, LH | 3 |
| Sun, XD | 3 |
| Jia, Z | 3 |
| Ouyang, W | 3 |
| Ye, QS | 3 |
| Zhang, FX | 3 |
| Guo, YQ | 3 |
| Ai, YQ | 3 |
| Zhao, BJ | 3 |
| Yu, JB | 3 |
| Liu, ZH | 3 |
| Yin, N | 3 |
| Li, XY | 2 |
| Ma, JH | 2 |
| Li, HJ | 4 |
| Wang, MR | 2 |
| Sessler, DI | 2 |
| Wang, DX | 4 |
| Coeckelenbergh, S | 1 |
| Soucy-Proulx, M | 1 |
| Radtke, FM | 1 |
| Sun, Z | 1 |
| Sui, J | 1 |
| Kendall, MC | 1 |
| Ashrafizadeh, M | 1 |
| Ahmadi, Z | 1 |
| Farkhondeh, T | 1 |
| Samarghandian, S | 1 |
| Schaefer, MS | 1 |
| Raub, D | 1 |
| Xu, X | 1 |
| Shay, D | 1 |
| Teja, B | 1 |
| Chhangani, K | 1 |
| Grabitz, SD | 1 |
| O'Gara, B | 1 |
| Kienbaum, P | 1 |
| Houle, TT | 1 |
| Landoni, G | 1 |
| Eikermann, M | 1 |
| Gao, X | 1 |
| Mi, Y | 1 |
| Guo, N | 1 |
| Luan, J | 1 |
| Xu, H | 1 |
| Hu, Z | 1 |
| Wang, N | 1 |
| Zhang, D | 1 |
| Gou, X | 1 |
| Xu, L | 1 |
| Guo, L | 1 |
| Lin, F | 1 |
| Dai, H | 1 |
| Du, X | 1 |
| Yu, M | 1 |
| Zhang, J | 1 |
| Huang, H | 1 |
| Ge, W | 1 |
| Tao, G | 1 |
| Pan, L | 1 |
| Xu, Y | 1 |
| Pan, S | 1 |
| Jiang, W | 1 |
| Xue, F | 1 |
| Zhu, X | 1 |
| Chang, CY | 1 |
| Wu, MY | 1 |
| Chien, YJ | 1 |
| Su, IM | 1 |
| Wang, SC | 1 |
| Kao, MC | 1 |
| Dubowitz, JA | 1 |
| De Silva, AP | 1 |
| Braat, S | 1 |
| Shan, D | 1 |
| Yee, K | 1 |
| Hollande, F | 1 |
| Martin, O | 1 |
| Sloan, EK | 1 |
| Riedel, B | 2 |
| Alam, A | 1 |
| Rampes, S | 1 |
| Patel, S | 1 |
| Hana, Z | 1 |
| Nikova, A | 1 |
| Vlotinou, P | 1 |
| Karanikas, M | 1 |
| Tsoleridis, Т | 1 |
| Bakalinis, E | 1 |
| Tselepidis, V | 1 |
| Ntatsis, K | 1 |
| Takeyama, E | 1 |
| Miyo, M | 1 |
| Matsumoto, H | 2 |
| Tatsumi, K | 1 |
| Amano, E | 1 |
| Hirao, M | 1 |
| Shibuya, H | 1 |
| Selby, LV | 1 |
| Fernandez-Bustamante, A | 1 |
| Ejaz, A | 1 |
| Gleisner, A | 1 |
| Pawlik, TM | 1 |
| Douin, DJ | 1 |
| Monreal-Carrillo, E | 1 |
| Allende-Pérez, S | 1 |
| Hui, D | 1 |
| García-Salamanca, MF | 1 |
| Bruera, E | 1 |
| Verástegui, E | 1 |
| Soltanizadeh, S | 1 |
| Degett, TH | 1 |
| Gögenur, I | 1 |
| Rogerson, CM | 1 |
| Abulebda, K | 1 |
| Hobson, MJ | 1 |
| Wang, J | 2 |
| Cheng, CS | 1 |
| Lu, Y | 1 |
| Ding, X | 1 |
| Zhu, M | 1 |
| Miao, C | 1 |
| Jia, HQ | 1 |
| Yang, XD | 1 |
| Zhang, QG | 1 |
| Tan, HY | 2 |
| Bonilla-García, JL | 1 |
| Cortiñas-Sáenz, M | 1 |
| Pozo-Gavilán, ED | 1 |
| Oh, TK | 1 |
| Park, B | 1 |
| Lee, DE | 1 |
| Eom, W | 1 |
| Kang, S | 1 |
| Jiang, S | 1 |
| Liu, Y | 1 |
| Huang, L | 1 |
| Zhang, F | 1 |
| Kang, R | 1 |
| Shan, GJ | 1 |
| Zhu, SN | 1 |
| Perry, NJS | 1 |
| Yıldırım, İ | 1 |
| I Çelik, A | 1 |
| B Bay, S | 1 |
| Pasin, Ö | 1 |
| Tütüncü, AÇ | 1 |
| Yap, A | 1 |
| Lopez-Olivo, MA | 1 |
| Dubowitz, J | 1 |
| Hiller, J | 1 |
| Miele, E | 1 |
| Angela, M | 1 |
| Cefalo, MG | 1 |
| Del Bufalo, F | 1 |
| De Pasquale, MD | 1 |
| Annalisa, S | 1 |
| Spinelli, GP | 1 |
| Luigi, S | 1 |
| Enlund, M | 2 |
| Enlund, A | 2 |
| Berglund, A | 2 |
| Bergkvist, L | 2 |
| Andreasson, K | 1 |
| Cicek, C | 1 |
| Liu, TC | 1 |
| Miyata, T | 1 |
| Honma, R | 1 |
| Sato, A | 1 |
| Koyama, H | 1 |
| Tagawa, M | 1 |
| Przybyłowski, K | 1 |
| Tyczka, J | 1 |
| Szczesny, D | 1 |
| Bienert, A | 1 |
| Wiczling, P | 1 |
| Kut, K | 1 |
| Plenzler, E | 1 |
| Kaliszan, R | 1 |
| Grześkowiak, E | 1 |
| Patel, MM | 1 |
| Kamat, PP | 1 |
| McCracken, CE | 1 |
| Simon, HK | 1 |
| Wang, X | 1 |
| Wang, Q | 1 |
| Ge, H | 1 |
| Tao, L | 1 |
| Ball, C | 1 |
| Thomson, KR | 1 |
| Kavnoudias, H | 1 |
| Chiaretti, A | 1 |
| Ruggiero, A | 1 |
| Barbi, E | 1 |
| Pierri, F | 1 |
| Maurizi, P | 1 |
| Fantacci, C | 1 |
| Bersani, G | 1 |
| Riccardi, R | 1 |
| Inada, T | 2 |
| Kubo, K | 1 |
| Shingu, K | 2 |
| Rakes, LC | 1 |
| Shearer, JR | 1 |
| Bikhazi, GB | 1 |
| Friaa, O | 1 |
| Maillard, P | 1 |
| Brault, D | 1 |
| Sánchez-Pedrosa, G | 1 |
| Garutti, I | 1 |
| Moraga, FJ | 1 |
| Orozco, HD | 1 |
| Hamilton, H | 1 |
| Faughnan, LG | 2 |
| Burgoyne, LL | 1 |
| Hankins, GM | 1 |
| Smeltzer, MP | 1 |
| Pui, CH | 1 |
| Frei-Welte, M | 1 |
| Weiss, M | 1 |
| Neuhaus, D | 1 |
| Ares, C | 1 |
| Mauch, J | 1 |
| Möller Petrun, A | 1 |
| Kamenik, M | 1 |
| Punj, J | 1 |
| Bhatnagar, S | 1 |
| Saxena, A | 1 |
| Mishra, S | 1 |
| Kannan, TR | 1 |
| Panigrahi, M | 1 |
| Pandey, V | 1 |
| Zeng, WA | 1 |
| Lin, WQ | 1 |
| Xu, MX | 1 |
| Klein, SM | 1 |
| Hauser, GJ | 1 |
| Anderson, BD | 1 |
| Shad, AT | 1 |
| Gootenberg, JE | 1 |
| Dalton, HJ | 1 |
| Hertzog, JH | 1 |
| Ohara, T | 1 |
| Takahashi, M | 1 |
| Yamamoto, Y | 1 |
| Nakaho, T | 1 |
| Yamamuro, M | 1 |
| Keidan, I | 2 |
| Perel, A | 2 |
| Shabtai, EL | 1 |
| Pfeffer, RM | 1 |
| Overdyk, FJ | 1 |
| Glaisyer, HR | 1 |
| Sury, MRJ | 1 |
| Gottschling, S | 1 |
| Meyer, S | 1 |
| Krenn, T | 1 |
| Reinhard, H | 1 |
| Lothschuetz, D | 1 |
| Nunold, H | 1 |
| Graf, N | 1 |
| Lundström, S | 1 |
| Zachrisson, U | 1 |
| Fürst, CJ | 1 |
| Kushida, A | 1 |
| Yu, C | 1 |
| Luo, YL | 1 |
| Xiao, SS | 1 |
| Zhang, Q | 1 |
| Chen, SL | 1 |
| González-Arrieta, ML | 1 |
| Juárez Melendez, J | 1 |
| Silva Hernández, J | 1 |
| Galindo Fabian, A | 1 |
| Labastida, S | 1 |
| Campos, A | 1 |
| Jiménez Villarruel, M | 1 |
| Moyle, J | 1 |
| Setlock, MA | 1 |
| Palmisano, BW | 1 |
| Berens, RJ | 1 |
| Rosner, DR | 1 |
| Troshynski, TJ | 1 |
| Murray, KJ | 1 |
| Scheiber, G | 1 |
| Ribeiro, FC | 1 |
| Karpienski, H | 1 |
| Strehl, K | 1 |
| Dakin, MJ | 1 |
| Devchand, D | 1 |
| Berkenstadt, H | 1 |
| Sidi, A | 1 |
| Ivani, G | 1 |
| Della Rocca, M | 1 |
| De Negri, P | 1 |
| Corca, D | 1 |
| Cuneo, GP | 1 |
| Caffarena, PE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Long-term Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT02660411] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Completed | |||
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on Incidence of Postoperative Delirium in Elderly Patients After Cancer Surgery: An Open-label, Randomized Controlled Trial[NCT02662257] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Completed | |||
| Comparison of Propofol and Sevoflurane Anesthesia on the Quality of Recovery After Ambulatory Surgery for Anal Fistula in Obese Patients: A Prospective, Randomized, Single-blinded, Controlled Clinical Trial[NCT05529875] | 0 participants (Actual) | Interventional | 2022-10-31 | Withdrawn (stopped due to In the early stage of the research, this research was limited by the application permission of research drugs and instruments, and the research will have to be interrupted, which is extremely regrettable.) | |||
| Impact of Remimazolam Tosilate for General Anesthesia on Prognosis After Bladder Cancer Surgery: a Randomized Controlled Trial[NCT04532606] | Phase 4 | 1,128 participants (Anticipated) | Interventional | 2021-02-05 | Recruiting | ||
| A Randomized, Open-label Study to Compare Propofol Anesthesia With Sevoflurane Anesthesia in Terms of Overall Survival in Patients With Surgical Intervention for Either Breast-, Colon- or Rectal Cancer[NCT01975064] | Phase 4 | 5,774 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| Impact of Inhalational Versus Intravenous Anesthesia Maintenance Methods on 5-year Survival in Elderly Patients After Cancer Surgery: a Randomized Controlled Trial[NCT05343260] | 1,228 participants (Actual) | Interventional | 2015-04-01 | Active, not recruiting | |||
| Cancer Mortality Affected by the Choice of Anesthetic Drugs?[NCT01418326] | 3,284 participants (Actual) | Observational | 2010-11-30 | Completed | |||
| Effects of Dexmedetomidine on Anaesthesia During IRE Procedures for Solid Tumours[NCT02044224] | Phase 4 | 30 participants (Anticipated) | Interventional | 2014-01-31 | Completed | ||
| Studio Clinico Pilota Con Uso di Elettroporazione Irreversibile (IRE) Nel Trattamento di Lesioni Neoplastiche Epatiche Con Localizzazione ad accessibilità Limitata o ad Alto Rischio[NCT01442324] | 5 participants (Anticipated) | Interventional | 2011-02-28 | Recruiting | |||
| Total XV - Total Therapy Study XV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia[NCT00137111] | Phase 3 | 501 participants (Actual) | Interventional | 2000-07-08 | Completed | ||
| Comparison of Leg Elevation and Leg Wrapping in the Prevention of Propofol Induced Hypotension: A Prospective Randomised Controlled Study[NCT02845921] | 150 participants (Anticipated) | Interventional | 2016-01-31 | Recruiting | |||
| Comparison of the Effects of Total Intravenous Anesthesia and Inhalation Anesthesia on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and the Mechanism Involved: a Single-center, Randomized, Prospective Study[NCT03193710] | 260 participants (Anticipated) | Observational | 2017-09-01 | Recruiting | |||
| Evaluation of the Development of Tolerance to Sevoflurane in Children Undergoing Repeated Anesthesia Exposure[NCT04188782] | 24 participants (Actual) | Observational | 2019-11-20 | Completed | |||
| The Effects of Propofol Based Intravenous vs Sevoflurane Inhalation Anaesthesia on Inflammation and Circulating Tumor Cells in Paediatric Tumor Surgery - a Pilot Study[NCT04475705] | Phase 4 | 100 participants (Anticipated) | Interventional | 2021-01-11 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"White blood cell (leukocytes) counts in peripheral blood by Complete Blood Count~Measurement: Percentage change of leukemia cells from baseline" (NCT00137111)
Timeframe: Immediately before the methotrexate infusion and three days after subsequent infusion
| Intervention | Percent change (Mean) |
|---|---|
| 4 hr | -44 |
| 24 hr | -50 |
CCR was measured from end of week 56 therapy to the date of first treatment failure of any kind (relapse, death, lineage switch, or second malignancy) or to the last date of follow-up. Measurement was determined by Kaplan-Meyer estimate. (NCT00137111)
Timeframe: Median follow up time (range) 4.5 (1 to 7.8) years
| Intervention | Percentage of participants (Number) |
|---|---|
| Patients With High Risk of CNS Relapse | 92.2 |
Children were randomly assigned to receive initial single-agent treatment with HDMTX (1g/m^2) as either a 24-hour infusion or a 4-hour infusion and the outcome measure was the accumulation of MTXPG in leukemia cells. (NCT00137111)
Timeframe: 42 hours after start of high dose methotrexate infusion (HDMTX)
| Intervention | pmol/1,000,000,000 cells (Mean) |
|---|---|
| 4 hr | 1688 |
| 24 hr | 2521 |
EFS was measured from the start of on-study to the date of first treatment failure of any kind (relapse, death, lineage switch, or second malignancy) or to the last date of follow-up. Failure to enter remission was considered an event at time zero. Measurement was determined by Kaplan-Meyer estimate. (NCT00137111)
Timeframe: Median follow-up time (range) 5.6 (1.3 to 8.9) years
| Intervention | Percentage of Participants (Number) |
|---|---|
| Total Therapy | 87.3 |
Prednisolone sensitivity was measured in primary leukemia cells from bone marrow collected at diagnosis. Expression of CASP1 was determined by HG-U133A microarray. Values given are gene expression values, and the unit is arbitrary units (AU) defined as scaled fluorescence measured on microarray. (NCT00137111)
Timeframe: Pre-treatment
| Intervention | arbitrary units (Median) | |
|---|---|---|
| Prednisolone-sensitive cells | Prednisolone-resistant cells | |
| Total Therapy | 341.3 | 447.9 |
Prednisolone sensitivity was measured in primary leukemia cells from bone marrow collected at diagnosis. Expression of NLRP3 was determined by HG-U133A microarray. Values given are gene expression values, and the unit is arbitrary units (AU) defined as scaled fluorescence measured on microarray. (NCT00137111)
Timeframe: Pre-treatment
| Intervention | arbitrary units (Median) | |
|---|---|---|
| Prednisolone-sensitive cells | Prednisolone-resistant cells | |
| Total Therapy | 41.2 | 110.7 |
Detection of MRD at end of induction where positive MRD was defined as one or more leukemic cell per 10,000 mononuclear bone-marrow cells (>=0.01%). (NCT00137111)
Timeframe: End of Induction (Day 46 MRD measurement)
| Intervention | participants (Number) | |
|---|---|---|
| Negative <0.01% | Positive >= 0.01% | |
| Total Therapy | 390 | 102 |
17 reviews available for propofol and Benign Neoplasms
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
Targeting miRNAs with anesthetics in cancer: Current understanding and future perspectives.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Animals; Gene Expression Regu | 2021 |
General Anesthetics in Cancer Surgery: Can Anesthesiologists Help the Patient with More than a Safe Sleep.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesiologists; Anesthetics, General; Anesthetic | 2022 |
Anaesthetic Techniques and Strategies: Do They Influence Oncological Outcomes?
Topics: Anesthesia, Conduction; Anesthesia, General; Anesthetics; Humans; Neoplasms; Propofol | 2023 |
Anti-tumor Activity of Propofol: A Focus on MicroRNAs.
Topics: Animals; Antineoplastic Agents; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Neoplasms | 2020 |
The mechanism of propofol in cancer development: An updated review.
Topics: Humans; Hypnotics and Sedatives; Neoplasms; Propofol | 2020 |
Effects of propofol on the development of cancer in humans.
Topics: Anesthetics, Intravenous; Animals; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Propof | 2020 |
Anesthesia and Long-term Oncological Outcomes: A Systematic Review and Meta-analysis.
Topics: Administration, Inhalation; Administration, Intravenous; Aged; Anesthetics, Inhalation; Anesthetics, | 2021 |
Anesthetics or anesthetic techniques and cancer surgical outcomes: a possible link.
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Humans; Neoplasms; Propofol; Retrospective Studi | 2021 |
Association Between Anesthesia Delivered During Tumor Resection and Cancer Survival: a Systematic Review of a Mixed Picture with Constant Themes.
Topics: Anesthesia; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Neop | 2021 |
Outcomes of cancer surgery after inhalational and intravenous anesthesia: A systematic review.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2017 |
Novel Findings of Anti-cancer Property of Propofol.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Humans; Neoplasms; Propofol | 2018 |
Effects of propofol on cancer development and chemotherapy: Potential mechanisms.
Topics: Anesthetics, Intravenous; Animals; Antineoplastic Agents; Biomarkers, Tumor; Cell Transformation, Ne | 2018 |
Anesthetic technique and cancer outcomes: a meta-analysis of total intravenous versus volatile anesthesia.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2019 |
Possible link between cyclooxygenase-inhibiting and antitumor properties of propofol.
Topics: Anesthetics, Intravenous; Animals; Antineoplastic Agents; Cyclooxygenase 2 Inhibitors; Cyclooxygenas | 2011 |
[Perioperative tumour dissemination. 2. Effects of anaesthesia and analgesia].
Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthesia; Anesthetics; Humans; Neoplasm Metastasis; Neo | 2012 |
[Pediatric anesthesia for proton radiotherapy : medicine remote from the medical centre].
Topics: Ambulatory Care; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Child; Child, Presch | 2012 |
20 trials available for propofol and Benign Neoplasms
| Article | Year |
|---|---|
Long-term survival in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: follow-up of a multicentre randomised trial.
Topics: Aged; Anesthesia, Inhalation; Anesthetics, Intravenous; Cancer Survivors; Female; Follow-Up Studies; | 2023 |
Delirium in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: a multicentre randomised trial. Comment on Br J Anaesth 2023; 131: 253-65.
Topics: Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Delirium; Humans; Methyl Ethers | 2023 |
Delirium in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: a multicentre randomised trial. Comment on Br J Anaesth 2023; 131: 253-65.
Topics: Aged; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Delirium; Humans; Methyl Ethers | 2023 |
Impact of Sevoflurane Versus Propofol Anesthesia on Post-Operative Cognitive Dysfunction in Elderly Cancer Patients: A Double-Blinded Randomized Controlled Trial.
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Double-Blind Method; Female; Follow-Up Stud | 2020 |
Volatile anaesthesia and peri-operative outcomes related to cancer: a feasibility and pilot study for a large randomised control trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhala | 2021 |
Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial.
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Chi | 2017 |
Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial.
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Chi | 2017 |
Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial.
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Chi | 2017 |
Impact of inhalational versus intravenous anaesthesia on early delirium and long-term survival in elderly patients after cancer surgery: study protocol of a multicentre, open-label, and randomised controlled trial.
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Chi | 2017 |
Propofol compared with sevoflurane general anaesthesia is associated with decreased delayed neurocognitive recovery in older adults.
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Cog | 2018 |
Rationale and Design of the CAN Study: an RCT of Survival after Propofol- or Sevoflurane-based Anesthesia for Cancer Surgery.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Multicenter Studies as Topic; | 2019 |
Effect of rCaIFN-γ pretreatment on propofol-isoflurane suppression of NK cytotoxic activity in the peripheral blood of dogs.
Topics: Adaptive Immunity; Anesthesia, General; Anesthetics; Animals; Cytotoxicity Tests, Immunologic; Dogs; | 2015 |
Comparison of propofol versus propofol-ketamine combination in pediatric oncologic procedures performed by non-anesthesiologists.
Topics: Biopsy, Needle; Bone Marrow Examination; Child; Conscious Sedation; Female; Humans; Hypnotics and Se | 2011 |
Prospective randomized crossover evaluation of three anesthetic regimens for painful procedures in children with cancer.
Topics: Adolescent; Anesthesia; Anesthetics, Intravenous; Bone Marrow Examination; Child; Child, Preschool; | 2013 |
Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial.
Topics: Abdomen; Abdominal Neoplasms; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial P | 2013 |
Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial.
Topics: Abdomen; Abdominal Neoplasms; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial P | 2013 |
Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial.
Topics: Abdomen; Abdominal Neoplasms; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial P | 2013 |
Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized, clinical trial.
Topics: Abdomen; Abdominal Neoplasms; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Arterial P | 2013 |
[Effects of midazolam premedication on induction doses of propofol and hemodynamic changes during tumor patient induction].
Topics: Adjuvants, Anesthesia; Adult; Aged; Anti-Anxiety Agents; Female; Hemodynamics; Humans; Hypnotics and | 2002 |
Comparison of intermittent versus continuous infusion of propofol for elective oncology procedures in children.
Topics: Adolescent; Adult; Ambulatory Care; Anesthesia, Intravenous; Anesthetics, Intravenous; Antineoplasti | 2003 |
Children undergoing repeated exposures for radiation therapy do not develop tolerance to propofol: clinical and bispectral index data.
Topics: Anesthetics, Intravenous; Blood Pressure; Child; Child, Preschool; Drug Tolerance; Female; Heart Rat | 2004 |
Recovery after anesthesia for short pediatric oncology procedures: propofol and remifentanil compared with propofol, nitrous oxide, and sevoflurane.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation | 2005 |
Propofol versus midazolam/ketamine for procedural sedation in pediatric oncology.
Topics: Adolescent; Anesthetics, Dissociative; Child; Child, Preschool; Conscious Sedation; Humans; Hypnotic | 2005 |
When nothing helps: propofol as sedative and antiemetic in palliative cancer care.
Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Comorbidity; Female; Humans; Hypnotics and Sedatives; M | 2005 |
Total intravenous anesthesia with propofol vs. propofol/midazolam in oncology patients.
Topics: Adult; Aged; Anesthesia, Intravenous; Drug Interactions; Female; Humans; Male; Midazolam; Middle Age | 1995 |
Propofol/remifentanil versus propofol alone for bone marrow aspiration in paediatric haemato-oncological patients.
Topics: Adolescent; Analgesics, Opioid; Anesthesia, Intravenous; Anesthetics, Intravenous; Biopsy, Needle; B | 2001 |
44 other studies available for propofol and Benign Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Synthesis and characterization of novel PUFA esters exhibiting potential anticancer activities: an in vitro study.
Topics: Antineoplastic Agents; Apoptosis; Arachidonic Acid; Caspase 3; Cell Line, Tumor; Esters; Fatty Acids | 2011 |
The inhibition of circular RNA circNOLC1 by propofol/STAT3 attenuates breast cancer stem cells function via miR-365a-3p/STAT3 signaling.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Ne | 2021 |
Association between sedation and small neoplasm detection during diagnostic esophagogastroduodenoscopy: a propensity score-matched retrospective study.
Topics: Anesthesia; Conscious Sedation; Endoscopy, Digestive System; Humans; Neoplasms; Propensity Score; Pr | 2022 |
Impact of Propofol-based Total Intravenous Anesthesia Versus Inhalation Anesthesia on Long-term Survival After Cancer Surgery in a Nationwide Cohort.
Topics: Adult; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation | 2023 |
Volatile anesthesia versus propofol-based total intravenous anesthesia: A retrospective analysis of charts of patients who underwent elective digestive tract cancer curative surgeries.
Topics: Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Fem | 2022 |
The Efficacy of Remifentanil Combined with Propofol in Craniotomy for Tumor Was Evaluated by Wake Quality, Hemodynamics, and Adverse Reactions.
Topics: Anesthetics, Intravenous; Craniotomy; Hemodynamics; Humans; Neoplasms; Piperidines; Propofol; Remife | 2022 |
Dexmedetomidine and Propofol at End of Life in Pediatric Oncology: Trends in Palliative Sedation Therapy.
Topics: Child; Death; Dexmedetomidine; Humans; Neoplasms; Pain; Palliative Care; Propofol; Prospective Studi | 2023 |
The differential cancer growth associated with anaesthetics in a cancer xenograft model of mice: mechanisms and implications of postoperative cancer recurrence.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Caco-2 Cells; Heterografts; Humans; Lipo | 2023 |
Propofol doses differ in total intravenous anaesthesia (TIVA) for cancer and no cancer surgery - observational cohort study.
Topics: Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Body Weight; Cohort Studies; | 2022 |
Anesthetic propofol inhibits ferroptosis and aggravates distant cancer metastasis via Nrf2 upregulation.
Topics: Anesthetics; Animals; Mice; Neoplasms; NF-E2-Related Factor 2; Propofol; Sevoflurane; Up-Regulation | 2023 |
Anaesthesia, analgesia, and cancer outcomes: time to think like oncologists?
Topics: Aged; Analgesia; Anesthesia, General; Anesthesiology; Anesthetics; Follow-Up Studies; Humans; Neopla | 2023 |
Dexmedetomidine for cancer surgery: A short-term infusion with long-term benefits. Or just another smoking mirror?
Topics: Dexmedetomidine; Humans; Hypnotics and Sedatives; Neoplasms; Propofol; Smoking | 2023 |
Delirium in older patients given propofol or sevoflurane anaesthesia for major cancer surgery: a multicentre randomised trial.
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Emergence Delirium; Female; Follow-Up Studies; H | 2023 |
Sedation target and propofol dosage in pediatric patients.
Topics: Anesthetics, Intravenous; Child; Child, Preschool; Cohort Studies; Conscious Sedation; Dose-Response | 2019 |
Association between propofol dose and 1-year mortality in patients with or without a diagnosis of solid cancer.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Dose-Response Relationship, Drug; Female | 2020 |
Which is the Prognostic Value of the Mini Mental State Examination Test in Surgical Oncology?
Topics: Benzodiazepines; Humans; Mental Status and Dementia Tests; Neoplasms; Prognosis; Propofol; Surgical | 2021 |
Long-term survival differences between sevoflurane and propofol use in general anesthesia for gynecologic cancer surgery.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Female; Humans; Methyl Ether | 2021 |
Bispectral Index monitoring in cancer patients undergoing palliative sedation: a preliminary report.
Topics: Adult; Aged; Awareness; Cancer Pain; Conscious Sedation; Consciousness; Delirium; Electroencephalogr | 2017 |
Association of BMI With Propofol Dosing and Adverse Events in Children With Cancer Undergoing Procedural Sedation.
Topics: Adolescent; Biopsy, Needle; Body Mass Index; Bone Marrow; Child; Child, Preschool; Deep Sedation; Hu | 2017 |
Opioids and immunosupression in oncological postoperative patients.
Topics: Aged; Analgesics, Opioid; Cross Infection; Female; Humans; Immunosuppressive Agents; Male; Midazolam | 2017 |
Factors affecting propofol dosage for sedation in pediatric oncology.
Topics: Child; Child, Preschool; Deep Sedation; Dose-Response Relationship, Drug; Female; Humans; Hypnotics | 2018 |
Can Anesthesia Influence Cancer Outcomes After Surgery?
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Immunity, Cellular; | 2019 |
Propofol-based balanced anesthesia is safer in pediatric radiotherapy.
Topics: Adolescent; Anesthesia; Balanced Anesthesia; Child; Child, Preschool; Female; Humans; Incidence; Inf | 2019 |
Propofol-based palliative sedation in terminally ill children with solid tumors: A case series.
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Hypnotics and Sedatives; Male; Neoplasms; Pain; | 2019 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
The choice of anaesthetic--sevoflurane or propofol--and outcome from cancer surgery: a retrospective analysis.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Methyl Ethers; Neoplasms; Propofol; Retro | 2014 |
Influence of propofol, isoflurane and enflurance on levels of serum interleukin-8 and interleukin-10 in cancer patients.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Enflurane; Female; Humans; Inflammat | 2014 |
Pharmacokinetics and pharmacodynamics of propofol in cancer patients undergoing major lung surgery.
Topics: Aged; Anesthetics, Intravenous; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Infusion | 2015 |
Complications of Deep Sedation for Individual Procedures (Lumbar Puncture Alone) Versus Combined Procedures (Lumbar Puncture and Bone Marrow Aspirate) in Pediatric Oncology Patients.
Topics: Airway Obstruction; Biopsy, Needle; Bone Marrow Examination; Child; Child, Preschool; Deep Sedation; | 2016 |
Propofol depresses cisplatin cytotoxicity via the inhibition of gap junctions.
Topics: Anesthetics, Intravenous; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Connexi | 2016 |
Irreversible electroporation: a new challenge in "out of operating theater" anesthesia.
Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; A | 2010 |
Irreversible electroporation: a new challenge in "out of operating theater" anesthesia.
Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; A | 2010 |
Irreversible electroporation: a new challenge in "out of operating theater" anesthesia.
Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; A | 2010 |
Irreversible electroporation: a new challenge in "out of operating theater" anesthesia.
Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; A | 2010 |
Prevention of emergence agitation in seven children receiving low-dose ketamine and propofol total intravenous anesthesia.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Child, Preschool; Drug Interactions; Humans; In | 2011 |
Reaction of the m-THPC triplet state with the antioxidant Trolox and the anesthetic Propofol: modulation of photosensitization mechanisms relevant to photodynamic therapy?
Topics: Anesthetics; Antioxidants; Chromans; Humans; Kinetics; Lasers; Mesoporphyrins; Neoplasms; Oxidation- | 2012 |
Pediatric palliative sedation therapy with propofol: recommendations based on experience in children with terminal cancer.
Topics: Adolescent; Child; Fatal Outcome; Humans; Hypnotics and Sedatives; Male; Medical Audit; Neoplasms; P | 2012 |
Propofol for pediatric radiotherapy.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Child; Child, Preschool; Female; Humans; Infant | 2002 |
[Use of propofol for painful procedures in cancer pain management].
Topics: Aged; Anesthesia, Local; Anesthetics, Intravenous; Female; Fractures, Spontaneous; Humans; Male; Mid | 2003 |
Lack of tolerance with propofol in radiation therapy needs patience.
Topics: Anesthetics, Intravenous; Child; Drug Tolerance; Humans; Neoplasms; Propofol | 2004 |
Enhancement of antitumor immunity after propofol treatment in mice.
Topics: Adjuvants, Immunologic; Animals; Blood Proteins; Body Weight; Cell Count; Cell Line, Tumor; Fat Emul | 2007 |
Enhancement of antitumor immunity after propofol treatment in mice.
Topics: Adjuvants, Immunologic; Animals; Blood Proteins; Body Weight; Cell Count; Cell Line, Tumor; Fat Emul | 2007 |
Enhancement of antitumor immunity after propofol treatment in mice.
Topics: Adjuvants, Immunologic; Animals; Blood Proteins; Body Weight; Cell Count; Cell Line, Tumor; Fat Emul | 2007 |
Enhancement of antitumor immunity after propofol treatment in mice.
Topics: Adjuvants, Immunologic; Animals; Blood Proteins; Body Weight; Cell Count; Cell Line, Tumor; Fat Emul | 2007 |
[Influence of propofol and isoflurane on cytokines response to cancer surgery during perioperative period].
Topics: Adult; Anesthesia, Intravenous; Cytokines; Female; Humans; Interleukin-10; Interleukin-6; Isoflurane | 2007 |
The use of propofol in palliative medicine.
Topics: Aged; Anesthetics, Intravenous; Delirium; Humans; Hypnotics and Sedatives; Male; Neoplasms; Palliati | 1995 |
Tolerance to propofol generally does not develop in pediatric patients undergoing radiation therapy.
Topics: Anesthetics, Inhalation; Child, Preschool; Drug Tolerance; Female; Humans; Infant; Male; Neoplasms; | 1996 |
Deep sedation with propofol in preschool children undergoing radiation therapy.
Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Child | 1996 |
Deep sedation with propofol for paediatric radiotherapy.
Topics: Anesthetics, Intravenous; Child; Child, Preschool; Conscious Sedation; Humans; Hypnotics and Sedativ | 1997 |
[Continuous-flow propofol in pediatric oncologic surgery].
Topics: Anesthesia, Intravenous; Child; Child, Preschool; Humans; Infusions, Intravenous; Neoplasms; Propofo | 1991 |