Page last updated: 2024-11-03

propofol and Benign Neoplasms, Brain

propofol has been researched along with Benign Neoplasms, Brain in 95 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"During propofol anesthesia at normoventilation, 50% of brain tumor patients showed signs suggesting cerebral hypoperfusion, but this could not be demonstrated during isoflurane/nitrous oxide anesthesia."9.09Jugular bulb oxygen saturation during propofol and isoflurane/nitrous oxide anesthesia in patients undergoing brain tumor surgery. ( Jansen, GF; Kedaria, MB; Odoom, JA; van Praagh, BH, 1999)
" The aim of the present study was to compare two techniques of anesthesia in patients with cerebral tumours: one of a balanced type (AB) and the other of a continuous ev type (AEC) using propofol in order to assess which guaranteed the greatest cerebral protection."9.07[Randomized study on the use of propofol for anesthesia in intracranial tumors. Comparison with balanced anesthesia]. ( Aloe, L; Imperatori, G; Margiotta, L; Mazzitelli, MR; Morace, E; Moricca, P; Sofra, M, 1992)
"Temozolomide (TMZ) is the first-line drug for the clinical treatment of glioblastoma (GBM), but drug resistance limits its treatment benefits."8.12Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression. ( Yun, K; Zhao, W, 2022)
"Using computerized tomography, we measured absolute cerebral blood flow (CBF) and cerebral blood volume (CBV) in tumor, peri-tumor, and contralateral normal regions, at normocapnia and hypocapnia, in 16 rabbits with brain tumors (VX2 carcinoma), under isoflurane or propofol anesthesia."7.71Cerebral blood volume and blood flow responses to hyperventilation in brain tumors during isoflurane or propofol anesthesia. ( Cenic, A; Craen, RA; Gelb, AW; Lee, TY, 2002)
"Glioma is a common primary intracranial tumor, with high infiltration and aggression."5.62Propofol Represses Cell Growth and Metastasis by Modulating the Circular RNA Non-SMC Condensin I Complex Subunit G/MicroRNA-200a-3p/RAB5A Axis in Glioma. ( Chen, H; Tian, C; Zhang, L; Zheng, D, 2021)
"Post-operative cerebral edema is a threat for patients performed gliomas resection."5.42Effects of propofol and sevoflurane on aquaporin-4 and aquaporin-9 expression in patients performed gliomas resection. ( Chang, FF; Dong, H; Lu, SJ; Qian, H; Song, CY; Yang, WC; Yue, ZY; Zhang, R; Zhou, LJ, 2015)
"We report a case of a drug-induced acute pancreatitis that was most likely triggered by a single dosage of propofol."5.33Acute pancreatitis induced by short-term propofol administration. ( Gottschling, S; Graf, N; Larsen, R; Meyer, S; Reinhard, H, 2005)
" Twenty-nine patients undergoing craniotomy for frontotemporal gliomas were randomized to receive intravenous anesthesia with propofol or inhalational anesthesia with isoflurane."5.12Cerebrovascular reactivity to carbon dioxide in the normal and abnormal cerebral hemispheres under anesthesia in patients with frontotemporal gliomas. ( Pillai, SV; Rao, GS, 2006)
"The study indicates that before as well as during hyperventilation, subdural ICP and AVDo2 are lower and CPP higher in propofol-anesthetized patients compared with patients anesthetized with isoflurane or sevoflurane."5.10Intracranial pressure and cerebral hemodynamic in patients with cerebral tumors: a randomized prospective study of patients subjected to craniotomy in propofol-fentanyl, isoflurane-fentanyl, or sevoflurane-fentanyl anesthesia. ( Cold, GE; Hauerberg, J; Holst, P; Landsfeldt, U; Mau, S; Olsen, KS; Petersen, CB; Petersen, KD, 2003)
"During propofol anesthesia at normoventilation, 50% of brain tumor patients showed signs suggesting cerebral hypoperfusion, but this could not be demonstrated during isoflurane/nitrous oxide anesthesia."5.09Jugular bulb oxygen saturation during propofol and isoflurane/nitrous oxide anesthesia in patients undergoing brain tumor surgery. ( Jansen, GF; Kedaria, MB; Odoom, JA; van Praagh, BH, 1999)
" The aim of the present study was to compare two techniques of anesthesia in patients with cerebral tumours: one of a balanced type (AB) and the other of a continuous ev type (AEC) using propofol in order to assess which guaranteed the greatest cerebral protection."5.07[Randomized study on the use of propofol for anesthesia in intracranial tumors. Comparison with balanced anesthesia]. ( Aloe, L; Imperatori, G; Margiotta, L; Mazzitelli, MR; Morace, E; Moricca, P; Sofra, M, 1992)
"Our retrospective analysis of patients receiving monitored anesthesia care for awake craniotomy revealed that delayed awakening after propofol discontinuation occurred more often in patients with IDH1 wild-type tumors and repeated craniotomies."4.31Predictors for delayed awakening in adult glioma patients receiving awake craniotomy under monitored anesthesia care. ( Chang, WH; Chen, KT; Chen, PY; Chen, YC; Lin, CM; Lin, HT; Liu, FC; Wei, KC; Wu, YY, 2023)
" Previous research found no relationship between body mass index (BMI) and time-to-awake for intravenous anesthesia with propofol, which is a lipophilic agent."4.31Is assessment of skeletal muscle mass useful to predict time-to-awake in awake craniotomies? ( de Graaf, P; De Witt Hamer, PC; Lai, YM; Schober, P; van den Brom, CE; van Heusden, HC, 2023)
"Temozolomide (TMZ) is the first-line drug for the clinical treatment of glioblastoma (GBM), but drug resistance limits its treatment benefits."4.12Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression. ( Yun, K; Zhao, W, 2022)
" The aim of this study was to evaluate a potential influence of the anaesthetic method (inhaled anaesthetics versus total-intravenous anaesthesia using propofol) on recurrence-free and overall survival in glioblastoma patients."3.96The choice of anaesthesia for glioblastoma surgery does not impact the time to recurrence. ( Annecke, T; Grau, SJ; Hampl, J; Löhr, M; Schwab, SG; Taurisano, V; Timmer, M; Trautner, H, 2020)
"Genistein and propofol effectively inhibited growth of gliosarcoma cells and induced apoptosis."3.85Genistein exerts potent antitumour effects alongside anaesthetic, propofol, by suppressing cell proliferation and nuclear factor-κB-mediated signalling and through upregulating microRNA-218 expression in an intracranial rat brain tumour model. ( Liang, Y; Liu, H; Zheng, Y, 2017)
"We report the case of an aborted awake craniotomy for a left frontotemporoinsular glioma due to ammonia encephalopathy on a patient taking Levetiracetam, valproic acid and clobazam."3.81Ammonia encephalopathy and awake craniotomy for brain language mapping: cause of failed awake craniotomy. ( Arroyo Pérez, R; Fernández-Candil, JL; León Jorba, A; Pacreu Terradas, S; Villalba Martínez, G; Vivanco-Hidalgo, RM, 2015)
"The authors studied eight patients subjected to craniotomy under propofol-fentanyl anesthesia for supratentorial brain tumors."3.76Cerebral blood flow, blood volume, and mean transit time responses to propofol and indomethacin in peritumor and contralateral brain regions: perioperative perfusion-weighted magnetic resonance imaging in patients with brain tumors. ( Christensen, SM; Cold, GE; Gyldensted, C; Jónsdóttir, KY; Juul, N; Rasmussen, M; Vestergaard-Poulsen, P; Østergaard, L, 2010)
"Changes in cerebral blood flow velocity after the administration of propofol were assessed using bilateral 2 MHz transcranial Doppler probes in 47 patients undergoing surgery for brain tumours and in 22 patients undergoing surgery for aneurysms and angiomas."3.72Cerebral vascular reactivity response to anaesthetic induction with propofol in patients with intracranial space-occupying lesions and vascular malformations. ( Cunitz, G; Engelhardt, M; Harders, A; Schmieder, K; Schregel, W, 2003)
"Using computerized tomography, we measured absolute cerebral blood flow (CBF) and cerebral blood volume (CBV) in tumor, peri-tumor, and contralateral normal regions, at normocapnia and hypocapnia, in 16 rabbits with brain tumors (VX2 carcinoma), under isoflurane or propofol anesthesia."3.71Cerebral blood volume and blood flow responses to hyperventilation in brain tumors during isoflurane or propofol anesthesia. ( Cenic, A; Craen, RA; Gelb, AW; Lee, TY, 2002)
" The total dosage of propofol and the incidence of adverse events were significantly lower in group L than in group C before T3."3.11Effect of low-dose lidocaine on MEPs in patients undergoing intracranial tumor resection with propofol anesthesia: A randomized controlled trial. ( Jin, W; Liu, J; Liu, M; Wang, D; Wang, N; Zhou, X, 2022)
"Brain tumors are rarely present during pregnancy."3.01Awake surgery for glioma resection during pregnancy: a systematic review. ( Batista, S; Bertani, R; Bocanegra-Becerra, JE; Castillo-Huerta, NM; Costa Vieitas, F; Ludeña-Esquivel, A; Oliveira, LB; Takahashi, R, 2023)
"EA combined with general anesthesia is safe and effective for patients with craniocerebral tumor-removal operations involving cerebral eloquent areas."2.79[Electroacupuncture intervention combined with general anesthesia for craniocerebral operations]. ( Cai, PH; Chen, L; Fei, ZM; Gong, L; Gu, GS; Kong, LJ; Qiu, F; Shu, GW; Wang, JY; Xu, LY; Zhang, J, 2014)
"Indomethacin was given before induction of anaesthesia and the infusion was terminated after opening of the dura."2.71The effects of indomethacin on intracranial pressure and cerebral haemodynamics in patients undergoing craniotomy: a randomised prospective study. ( Cold, GE; Rasmussen, M; Tankisi, A, 2004)
"Remifentanil was used as the analgetic component in all groups."2.71[Comparison between TCI-TIVA, manual TIVA and balanced anaesthesia for stereotactic biopsy of the brain]. ( Czerner, S; Steude, U; Weninger, B; Weninger, E, 2004)
" Log dose-response curves for loss of response to verbal command and tetanic stimulus were calculated after logit transformation."2.69Propofol requirement is decreased in patients with large supratentorial brain tumor. ( Chan, MT; Gin, T; Poon, WS, 1999)
"Propofol has been suggested as an alternative to amobarbital, and while there is some published data on this, there is no reported Australian experience to date."2.52Propofol as a substitute for amobarbital in Wada testing. ( Bynevelt, M; Chiu, AH; Lawn, N; Lee, G; Singh, TP, 2015)
"Glioma is a common primary intracranial tumor, with high infiltration and aggression."1.62Propofol Represses Cell Growth and Metastasis by Modulating the Circular RNA Non-SMC Condensin I Complex Subunit G/MicroRNA-200a-3p/RAB5A Axis in Glioma. ( Chen, H; Tian, C; Zhang, L; Zheng, D, 2021)
"Propofol is an excellent hypnotic drug for use in repeated radiation procedures in young children."1.48Incidence of tolerance in children undergoing repeated administration of propofol for proton radiation therapy: a retrospective study. ( Gil, NS; Jeong, JS; Kang, R; Oh, YN; Shin, BS; Shin, YH, 2018)
"Post-operative cerebral edema is a threat for patients performed gliomas resection."1.42Effects of propofol and sevoflurane on aquaporin-4 and aquaporin-9 expression in patients performed gliomas resection. ( Chang, FF; Dong, H; Lu, SJ; Qian, H; Song, CY; Yang, WC; Yue, ZY; Zhang, R; Zhou, LJ, 2015)
"Propofol was associated with a better recovery profile and neurological condition than isoflurane, as indicated by shorter extubation and OR discharge times and better postoperative consciousness."1.38Superior recovery profiles of propofol-based regimen as compared to isoflurane-based regimen in patients undergoing craniotomy for primary brain tumor excision: a retrospective study. ( Kamiya, K; Kanazawa, K; Kawamae, K; Kumasaka, A; Miura, Y; Nakane, M; Okada, M, 2012)
"The propofol infusion was resumed while the cranium was closed and Mayfield tongs removed."1.36Nonopioid anesthesia for awake craniotomy: a case report. ( Gold, M; Naruse, R; Wolff, DL, 2010)
" It has been reported that remifentanil is suitable because of its wide dosage window with respect to recording MEP."1.35[Anesthetic management of a case of craniotomy using TCI of remifentanil with intraoperative monitoring of motor evoked potential]. ( Ito, T; Iwasaki, H; Kunisawa, T; Nagashima, M; Omachi, H; Ozaki, Y; Suzuki, A; Takahata, O, 2008)
" We describe an asleep-awake-asleep technique with propofol and remifentanil infusions, with pharmacokinetic simulation to predict the effect-site concentrations and to modulate the infusion rates of both drugs, and bispectral index (BIS) monitoring."1.34Propofol and remifentanil effect-site concentrations estimated by pharmacokinetic simulation and bispectral index monitoring during craniotomy with intraoperative awakening for brain tumor resection. ( Beiras, A; Lobo, F, 2007)
"We report a case of a drug-induced acute pancreatitis that was most likely triggered by a single dosage of propofol."1.33Acute pancreatitis induced by short-term propofol administration. ( Gottschling, S; Graf, N; Larsen, R; Meyer, S; Reinhard, H, 2005)
"Propofol has been used to treat convulsions, while the drug is known to induce convulsions."1.32[Refractory generalized convulsions in a patient undergoing brain tumor resection during propofol anesthesia]. ( Fukushima, H; Ishiyama, T; Kumazawa, T; Masui, K; Matsukawa, T; Oguchi, T, 2004)
"A propofol/ N2O regimen was compared with the isoflurane/O2 regimen, altering blood pressure, heart rate, and PaCO2 as covariates (n = 48)."1.30The influence of anesthetic choice, PaCO2, and other factors on osmotic blood-brain barrier disruption in rats with brain tumor xenografts. ( Fiamengo, SA; McCormick, CI; Neuwelt, EA; Pagel, MA; Remsen, LG; Sexton, G, 1999)
"Propofol is an intravenous anesthetic agent with a short half-life allowing rapid recovery; it has cerebral hemodynamic effects similar to those of thiopental."1.29[Use of propofol in intracranial surgery in 83 consecutive patients]. ( Borgeat, A; Gaggero, G; Ravussin, P; Wilder-Smith, O, 1994)

Research

Studies (95)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.11)18.7374
1990's17 (17.89)18.2507
2000's39 (41.05)29.6817
2010's24 (25.26)24.3611
2020's13 (13.68)2.80

Authors

AuthorsStudies
Erdman, HB1
Kornilov, E1
Kahana, E1
Zarchi, O1
Reiner, J1
Socher, A1
Strauss, I1
Firman, S1
Israel, Z1
Bergman, H1
Tamir, I1
Zhao, W1
Yun, K1
Liu, M1
Wang, N1
Wang, D1
Liu, J1
Zhou, X1
Jin, W1
Tomasino, B1
Guarracino, I1
Pauletto, G1
Pez, S1
Ius, T1
Furlan, D1
Nilo, A1
Isola, M1
De Martino, M1
Mauro, S1
Verriello, L1
Lettieri, C1
Gigli, GL1
Valente, M1
Deana, C1
Skrap, M1
Nizar, R1
Cazacu, S1
Xiang, C1
Krasner, M1
Barbiro-Michaely, E1
Gerber, D1
Schwartz, J1
Fried, I1
Yuval, S1
Brodie, A1
Kazimirsky, G1
Amos, N1
Unger, R1
Brown, S1
Rogers, L1
Penning, DH1
Brodie, C1
Bocanegra-Becerra, JE1
Batista, S1
Costa Vieitas, F1
Takahashi, R1
Oliveira, LB1
Castillo-Huerta, NM1
Ludeña-Esquivel, A1
Bertani, R1
Lin, HT1
Lin, CM1
Wu, YY1
Chang, WH1
Wei, KC1
Chen, YC1
Chen, PY1
Liu, FC1
Chen, KT1
Lai, YM1
van Heusden, HC1
de Graaf, P1
van den Brom, CE1
De Witt Hamer, PC2
Schober, P1
Grau, SJ1
Löhr, M1
Taurisano, V1
Trautner, H1
Timmer, M1
Schwab, SG1
Hampl, J1
Annecke, T1
Wang, AT1
Pillai, P1
Guran, E1
Carter, H1
Minasian, T1
Lenart, J1
Vandse, R1
Zhang, L1
Chen, H1
Tian, C1
Zheng, D1
Yamao, Y1
Matsumoto, R2
Kunieda, T1
Nakae, T1
Nishida, S1
Inano, R1
Shibata, S1
Kikuchi, T1
Arakawa, Y1
Yoshida, K1
Ikeda, A2
Miyamoto, S2
Hu, C1
Iwasaki, M1
Liu, Z1
Wang, B1
Li, X1
Lin, H1
Li, J1
Li, JV1
Lian, Q1
Ma, D1
Prontera, A1
Baroni, S1
Marudi, A1
Valzania, F1
Feletti, A1
Benuzzi, F1
Bertellini, E1
Pavesi, G1
Sahinovic, MM2
Eleveld, DJ1
Miyabe-Nishiwaki, T1
Struys, MMRF1
Absalom, AR2
Zheng, Y1
Liu, H1
Liang, Y1
Vickovic, S1
Ikonic, N1
Karan, V1
Karan, M1
Vulekovic, P1
Kang, R1
Shin, BS1
Shin, YH1
Gil, NS1
Oh, YN1
Jeong, JS1
Lee, WH1
Park, CK1
Park, HP1
Kim, SM1
Oh, BM1
Kim, K1
Choi, YD1
Seo, HG1
Miura, Y2
Chowdhury, T1
Cappellani, RB1
Beese, U1
Heeremans, EH1
Kalmar, A1
van Amsterdam, K1
Steenbakkers, RJ1
Kuiper, H1
Spanjersberg, R1
Groen, RJ1
Struys, MM1
Zhang, J1
Fei, ZM1
Shu, GW1
Cai, PH1
Wang, JY1
Xu, LY1
Kong, LJ1
Qiu, F1
Gong, L1
Chen, L1
Gu, GS1
Takeuchi, R1
Hoshijima, H1
Horikoshi, Y1
Nakamura, C1
Iwase, Y1
Nagasaka, H1
Villalba Martínez, G1
Fernández-Candil, JL1
Vivanco-Hidalgo, RM1
Pacreu Terradas, S1
León Jorba, A1
Arroyo Pérez, R1
Cao, SE1
Gao, BQ1
Zhang, YQ1
Yang, SM1
Liu, GZ1
Zhang, XR1
Yang, WC1
Zhou, LJ1
Zhang, R1
Yue, ZY1
Dong, H1
Song, CY1
Qian, H1
Lu, SJ1
Chang, FF1
Chiu, AH1
Bynevelt, M1
Lawn, N1
Lee, G1
Singh, TP1
Bisdas, S1
Charyasz-Leks, E1
Roder, C1
Tatagiba, MS1
Ernemann, U1
Klose, U1
Sonis, J1
Borczuk, P1
Ptak, T1
Miller, ES1
Mounir, K1
Bensghir, M1
Kamili, ND1
Rasmussen, M3
Juul, N2
Christensen, SM1
Jónsdóttir, KY1
Gyldensted, C2
Vestergaard-Poulsen, P1
Cold, GE4
Østergaard, L2
Conte, V1
Magni, L1
Songa, V1
Tomaselli, P1
Ghisoni, L1
Magnoni, S1
Bello, L1
Stocchetti, N1
Wolff, DL1
Naruse, R1
Gold, M1
Andersen, JH1
Olsen, KS3
Banevičius, G1
Rugytė, D1
Macas, A1
Tamašauskas, A1
Stankevičius, E1
Bossers, SM1
Peerdeman, SM1
Oedayrajsingh Varma, P1
Baayen, JC1
Schauer, A1
Loer, SA1
Boer, C1
Kamiya, K1
Kanazawa, K1
Okada, M1
Nakane, M1
Kumasaka, A1
Kawamae, K1
Ghouri, AF1
Mading, W1
Prabaker, K1
Yamaguchi, F1
Oi, Y1
Aoki, W1
Nakamura, R1
Igarashi, A1
Kubota, M1
Sawada, K1
Shimura, T1
Takahashi, H1
Kobayashi, S1
Teramoto, A1
Dueck, MH2
Oberthuer, A1
Wedekind, C1
Paul, M2
Boerner, U2
Petersen, KD1
Landsfeldt, U1
Petersen, CB1
Mau, S1
Hauerberg, J1
Holst, P1
Schmieder, K1
Schregel, W2
Engelhardt, M1
Harders, A1
Cunitz, G2
Tankisi, A1
Weninger, B1
Czerner, S1
Steude, U1
Weninger, E1
Fukushima, H1
Ishiyama, T1
Oguchi, T1
Masui, K1
Matsukawa, T1
Kumazawa, T1
Girard, F1
Moumdjian, R1
Boudreault, D1
Chouinard, P1
Bouthilier, A1
Sauvageau, E1
Ruel, M1
Girard, DC1
Takayama, M1
Mikuni, N1
Takahashi, JB1
Usui, K1
Satow, T1
Yamamoto, J1
Matsuhashi, M1
Nagamine, T1
Shibasaki, H1
Hashimoto, N1
Vitaz, TW1
Marx, W1
Victor, JD1
Gutin, PH1
Poulsen, PV1
Shukry, M1
Ramadhyani, U1
Brainer-Lima, PT1
Brainer-Lima, AM1
Brandt, CT1
Carneiro, GS1
Azevedo, HC1
Petzke, F1
Gerbershagen, HJ1
Hesselmann, V1
Girnus, R1
Krug, B1
Sorger, B1
Goebel, R1
Lehrke, R1
Sturm, V1
Keifer, JC1
Dentchev, D1
Little, K1
Warner, DS1
Friedman, AH1
Borel, CO1
Venkatesh, KH1
Chandramouli, BA1
Luo, W1
Li, YH1
Yang, JJ1
Tian, J1
Xu, JG1
Gottschling, S1
Larsen, R1
Meyer, S1
Graf, N1
Reinhard, H1
Manninen, PH1
Balki, M1
Lukitto, K1
Bernstein, M1
Everett, LL1
van Rooyen, IF1
Warner, MH1
Shurtleff, HA1
Saneto, RP1
Ojemann, JG1
Schulz, U1
Keh, D1
Fritz, G1
Barner, C1
Kerner, T1
Schneider, GH1
Trottenberg, T1
Kupsch, A1
Boemke, W1
Rao, GS1
Pillai, SV1
Hilton, G1
Andrzejowski, JC1
Raisis, AL1
Leece, EA1
Platt, SR1
Adams, VJ1
Corletto, F1
Brearley, J1
Lobo, F2
Beiras, A1
Weiss, M1
Frei, M1
Buehrer, S1
Feurer, R1
Goitein, G1
Timmermann, B1
Magni, G1
La Rosa, I2
Gimignani, S1
Melillo, G1
Imperiale, C1
Rosa, G2
Bordes, J1
Meaudre, E1
Asencio, Y1
Montcriol, A1
Kaiser, E1
Ferreira, DA1
Nunes, CS1
Casal, M1
Antunes, LM1
Amorim, P1
Kunisawa, T1
Ito, T1
Omachi, H1
Ozaki, Y1
Nagashima, M1
Suzuki, A1
Takahata, O1
Iwasaki, H1
Graham, D1
Gaggero, G1
Ravussin, P1
Borgeat, A1
Wilder-Smith, O1
Weiss, FR1
Schwartz, R1
Geissler, C1
Winking, M1
Schaefermeyer, H1
Tyler, DS1
Bacon, D1
Mahendru, V1
Lema, MJ1
Tobias, JD1
Jimenez, DF1
Metriyakool, K1
Bauman, GS1
Brett, CM1
Ciricillo, SF1
Larson, DA1
Sneed, P1
Staplers, LJ1
Edwards, M1
Wara, WM1
Remsen, LG1
Pagel, MA1
McCormick, CI1
Fiamengo, SA1
Sexton, G1
Neuwelt, EA1
Souweidane, MM1
Kim, KH1
McDowall, R1
Ruge, MI1
Lis, E1
Krol, G1
Hirsch, J1
Chan, MT1
Gin, T1
Poon, WS1
Schaffranietz, L1
Rüffert, H1
Trantakis, C1
Seifert, V1
Jansen, GF2
van Praagh, BH1
Kedaria, MB1
Odoom, JA1
Lentschener, C1
Benhamou, D1
Berkenstadt, H2
Ram, Z2
Fukaya, C1
Katayama, Y1
Yoshino, A1
Kobayashi, K1
Kasai, M1
Yamamoto, T1
Perel, A1
Hadani, M1
Unofrievich, I1
Cenic, A1
Craen, RA1
Lee, TY1
Gelb, AW1
Shinokuma, T1
Shono, S1
Iwakiri, S1
Shigematsu, K1
Higa, K1
Mazzitelli, MR1
Morace, E1
Sofra, M1
Aloe, L1
Moricca, P1
Margiotta, L1
Imperatori, G1
Orsi, P1
Sanità, R1
Di Giugno, G1
Kedaria, M1
Zuurmond, WW1
Van Aken, H2
Van Hemelrijck, J2
Merckx, L1
Möllhoff, T1
Mulier, J1
Lübbesmeyer, HJ1
Léon, A1
Ludot, H1
Graftieaux, JP1
Gomis, P1
Lamiable, D1
Rousseaux, P1
Rendoing, J1
Plets, C1
Goffin, J1
Vermaut, G1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Magnesium Sulphate Versus Fentanyl as Adjuvants to Propofol Xylocaine Combination for Conscious Sedation During Chronic Subdural Haematoma Surgery. Comparative Study[NCT03548493]Phase 234 participants (Actual)Interventional2018-04-10Completed
"Assessment of the Influence of Intracranial Space Occupying Lesions on the Reliability Off Monitoring of the Bispectral Index for Detection of Return of Consciousness."[NCT01060631]40 participants (Actual)Observational2009-11-30Completed
Cerebral Hyperemia During Emergence From General Anesthesia for Craniotomy of Patients With Brain Tumor[NCT01642147]60 participants (Actual)Interventional2012-11-30Completed
Influence of Vasopressors on Brain Oxygenation and Microcirculation in Anesthetized Patients With Cerebral Tumors[NCT02713087]Phase 448 participants (Actual)Interventional2015-09-30Completed
Comparison of Dexmedetomidine and Propofol-Remifentanil Conscious Sedation for Awake Craniotomy for Tumor Surgery: a Randomized Controlled Trial[NCT01545297]50 participants (Actual)Interventional2012-11-30Completed
Quality of Recovery Following Awake Craniotomy Versus Craniotomy Performed Under General Anesthesia[NCT02228993]84 participants (Actual)Observational2014-08-31Completed
A Prospective Randomized Controlled Trial of Electroconvulsive Therapy With Ketamine Anesthesia (Standard Therapy) and High Intensity Ketamine With Electroconvulsive Therapy Rescue for Treatment-Resistant Depression - EAST HIKER Trial[NCT03272698]Phase 462 participants (Anticipated)Interventional2017-09-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Mean Blood Flow Velocity in Middle Cerebral Artery

(NCT01642147)
Timeframe: 120min after extubation

Interventioncm/s (Mean)
Craniotomy Group69.7
Abdominal Surgery Group59.2

Mean Blood Flow Velocity in Middle Cerebral Artery

(NCT01642147)
Timeframe: 30min after extubation

Interventioncm/s (Mean)
Craniotomy Group82.5
Abdominal Surgery Group62.0

Mean Blood Flow Velocity in Middle Cerebral Artery

(NCT01642147)
Timeframe: 60min after extubation

Interventioncm/s (Mean)
Craniotomy Group77.0
Abdominal Surgery Group61.2

Mean Blood Flow Velocity in Middle Cerebral Artery

(NCT01642147)
Timeframe: 90min after extubation

Interventioncm/s (Mean)
Craniotomy Group72.8
Abdominal Surgery Group60.1

Mean Blood Flow Velocity in Middle Cerebral Artery

(NCT01642147)
Timeframe: after surgery at extubation (average surgery duration: craniotomy group 214min, abdominal group 207min)

Interventioncm/s (Mean)
Craniotomy Group95.7
Abdominal Surgery Group63.6

Mean Blood Flow Velocity in Middle Cerebral Artery

It was the baseline mean blood flow velocity in middle cerebral artery. (NCT01642147)
Timeframe: before general anesthesia

Interventioncm/s (Mean)
Craniotomy Group63.7
Abdominal Surgery Group61.8

Oxygen Saturation of Jugular Venous Bulb

(NCT01642147)
Timeframe: 120min after extubation

Interventionpercentage of oxygen saturation (Mean)
Craniotomy Group66.9

Oxygen Saturation of Jugular Venous Bulb

(NCT01642147)
Timeframe: 30min after extubation

Interventionpercentage of oxygen saturation (Mean)
Craniotomy Group77.0

Oxygen Saturation of Jugular Venous Bulb

(NCT01642147)
Timeframe: 60min after extubation

Interventionpercentage of oxygen saturation (Mean)
Craniotomy Group71.8

Oxygen Saturation of Jugular Venous Bulb

(NCT01642147)
Timeframe: 90min after extubation

Interventionpercentage of oxygen saturation (Mean)
Craniotomy Group68.8

Oxygen Saturation of Jugular Venous Bulb

(NCT01642147)
Timeframe: at extubation

Interventionpercentage of oxygen saturation (Mean)
Craniotomy Group81.4

Oxygen Saturation of Jugular Venous Bulb

(NCT01642147)
Timeframe: before general anesthesia

Interventionpercentage of oxygen saturation (Mean)
Craniotomy Group60.9

Reviews

4 reviews available for propofol and Benign Neoplasms, Brain

ArticleYear
Awake surgery for glioma resection during pregnancy: a systematic review.
    Neurosurgical review, 2023, Sep-06, Volume: 46, Issue:1

    Topics: Adult; Brain Neoplasms; Female; Glioma; Humans; Intraoperative Complications; Pregnancy; Propofol; W

2023
Propofol as a substitute for amobarbital in Wada testing.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:11

    Topics: Amobarbital; Australia; Brain Neoplasms; Craniotomy; Electroencephalography; Female; Humans; Hypnoti

2015
["Asleep-awake-asleep"-anaesthetic technique for awake craniotomy].
    Der Anaesthesist, 2006, Volume: 55, Issue:5

    Topics: Anesthesia; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Brain Neoplasms;

2006
Monitored anesthesia care in awake craniotomy for brain tumor surgery.
    The Israel Medical Association journal : IMAJ, 2001, Volume: 3, Issue:4

    Topics: Anesthesia; Anesthetics, Intravenous; Brain Neoplasms; Conscious Sedation; Craniotomy; Female; Hemod

2001

Trials

21 trials available for propofol and Benign Neoplasms, Brain

ArticleYear
Effect of low-dose lidocaine on MEPs in patients undergoing intracranial tumor resection with propofol anesthesia: A randomized controlled trial.
    Medicine, 2022, Aug-12, Volume: 101, Issue:32

    Topics: Anesthesia, General; Anesthetics, Intravenous; Brain Neoplasms; Evoked Potentials, Motor; Humans; Li

2022
[Electroacupuncture intervention combined with general anesthesia for craniocerebral operations].
    Zhen ci yan jiu = Acupuncture research, 2014, Volume: 39, Issue:1

    Topics: Acupuncture Analgesia; Acupuncture Points; Adolescent; Adult; Aged; Anesthesia, General; Brain Neopl

2014
Clinical application of remifentanil in local anesthesia for tumor resection in functional brain area.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:21

    Topics: Adult; Analgesics, Opioid; Anesthesia, Local; Anesthetics, Intravenous; Brain Neoplasms; Female; Gli

2014
The effects of sevoflurane and propofol on cerebral hemodynamics during intracranial tumors surgery under monitoring the depth of anesthesia.
    Medicina (Kaunas, Lithuania), 2010, Volume: 46, Issue:11

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Flow Velocity; Brain; Br

2010
Propofol impairs the central but not the peripheral part of the motor system.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:2

    Topics: Aged; Anesthetics, Intravenous; Axons; Brain Neoplasms; Central Nervous System; Craniotomy; Dose-Res

2003
Intracranial pressure and cerebral hemodynamic in patients with cerebral tumors: a randomized prospective study of patients subjected to craniotomy in propofol-fentanyl, isoflurane-fentanyl, or sevoflurane-fentanyl anesthesia.
    Anesthesiology, 2003, Volume: 98, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Inhalation; Anest

2003
The effects of indomethacin on intracranial pressure and cerebral haemodynamics in patients undergoing craniotomy: a randomised prospective study.
    Anaesthesia, 2004, Volume: 59, Issue:3

    Topics: Adult; Aged; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity;

2004
[Comparison between TCI-TIVA, manual TIVA and balanced anaesthesia for stereotactic biopsy of the brain].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2004, Volume: 39, Issue:4

    Topics: Analgesics; Anesthesia, Intravenous; Anesthetics, Intravenous; Biopsy; Blood Pressure; Brain Neoplas

2004
The effect of propofol sedation on the intracranial pressure of patients with an intracranial space-occupying lesion.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:2

    Topics: Aged; Biopsy; Blood Volume; Brain Neoplasms; Cerebrovascular Circulation; Double-Blind Method; Femal

2004
Cerebrospinal fluid and plasma propofol concentration during total intravenous anaesthesia of patients undergoing elective intracranial tumor removal.
    Journal of Zhejiang University. Science. B, 2005, Volume: 6, Issue:9

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Proteins; Brain Ne

2005
Patient satisfaction with awake craniotomy for tumor surgery: a comparison of remifentanil and fentanyl in conjunction with propofol.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Craniotomy; Drug Therapy, Combination; Female; Fentanyl; Humans; Male;

2006
Patient satisfaction with awake craniotomy for tumor surgery: a comparison of remifentanil and fentanyl in conjunction with propofol.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Craniotomy; Drug Therapy, Combination; Female; Fentanyl; Humans; Male;

2006
Patient satisfaction with awake craniotomy for tumor surgery: a comparison of remifentanil and fentanyl in conjunction with propofol.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Craniotomy; Drug Therapy, Combination; Female; Fentanyl; Humans; Male;

2006
Patient satisfaction with awake craniotomy for tumor surgery: a comparison of remifentanil and fentanyl in conjunction with propofol.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Craniotomy; Drug Therapy, Combination; Female; Fentanyl; Humans; Male;

2006
Cerebrovascular reactivity to carbon dioxide in the normal and abnormal cerebral hemispheres under anesthesia in patients with frontotemporal gliomas.
    Journal of neurosurgical anesthesiology, 2006, Volume: 18, Issue:3

    Topics: Adult; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Brain Neoplasms; Carbon Dioxid

2006
Transcranial Doppler monitoring during induction of anesthesia: effects of propofol, thiopental, and hyperventilation in patients with large malignant brain tumors.
    Journal of neurosurgical anesthesiology, 1993, Volume: 5, Issue:2

    Topics: Adult; Anesthesia, General; Astrocytoma; Brain Neoplasms; Female; Glioma; Hemodynamics; Humans; Hype

1993
Propofol requirement is decreased in patients with large supratentorial brain tumor.
    Anesthesiology, 1999, Volume: 90, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Blood Pressure; Brain Neoplasms; Dexamethasone; D

1999
[Effect of local anesthetics on hemodynamic effects during Mayfield skull clamp fixation in neurosurgery using total intravenous anesthesia].
    Anaesthesiologie und Reanimation, 1999, Volume: 24, Issue:2

    Topics: Alfentanil; Anesthesia, Inhalation; Anesthesia, Local; Blood Pressure; Brain Neoplasms; Bupivacaine;

1999
Jugular bulb oxygen saturation during propofol and isoflurane/nitrous oxide anesthesia in patients undergoing brain tumor surgery.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:2

    Topics: Adult; Anesthesia; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood F

1999
Intraoperative wake-up procedure with propofol and laryngeal mask for optimal excision of brain tumour in eloquent areas.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2001, Volume: 8, Issue:3

    Topics: Anesthetics, Intravenous; Brain Neoplasms; Conscious Sedation; Craniotomy; Glioma; Humans; Intraoper

2001
Monitored anesthesia care using remifentanil and propofol for awake craniotomy.
    Journal of neurosurgical anesthesiology, 2001, Volume: 13, Issue:3

    Topics: Analgesics, Opioid; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Brain Mapping

2001
[Randomized study on the use of propofol for anesthesia in intracranial tumors. Comparison with balanced anesthesia].
    Minerva anestesiologica, 1992, Volume: 58, Issue:4 Suppl 1

    Topics: Adult; Aged; Anesthesia; Anesthesia, Intravenous; Brain Neoplasms; Female; Hemodynamics; Humans; Mal

1992
Total intravenous anesthesia during intracranial surgery. Continuous propofol infusion in combination with either fentanyl or sufentanil.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:4 Pt 2

    Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics; Brain Neoplasms; Cerebrovascular Circulation; Fen

1990
[Total intravenous anesthesia using propofol and alfentanil in comparison with balanced anesthesia in neurosurgery].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1990, Volume: 25, Issue:1

    Topics: Adult; Aged; Alfentanil; Anesthesia, General; Anesthesia, Intravenous; Brain Neoplasms; Droperidol;

1990

Other Studies

70 other studies available for propofol and Benign Neoplasms, Brain

ArticleYear
Asleep DBS under ketamine sedation: Proof of concept.
    Neurobiology of disease, 2022, Volume: 170

    Topics: Anesthesia, General; Brain Neoplasms; Deep Brain Stimulation; Humans; Ketamine; Microelectrodes; Par

2022
Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression.
    Experimental cell research, 2022, 09-15, Volume: 418, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cyclooxygenase 2; Dru

2022
Performing real time neuropsychological testing during awake craniotomy: are dexmedetomidine or propofol the same? A preliminary report.
    Journal of neuro-oncology, 2022, Volume: 160, Issue:3

    Topics: Brain Neoplasms; Craniotomy; Dexmedetomidine; Humans; Hypnotics and Sedatives; Neuropsychological Te

2022
Propofol Inhibits Glioma Stem Cell Growth and Migration and Their Interaction with Microglia via BDNF-AS and Extracellular Vesicles.
    Cells, 2023, 07-25, Volume: 12, Issue:15

    Topics: Brain Neoplasms; Brain-Derived Neurotrophic Factor; Extracellular Vesicles; Glioblastoma; Glioma; Hu

2023
Predictors for delayed awakening in adult glioma patients receiving awake craniotomy under monitored anesthesia care.
    Journal of neuro-oncology, 2023, Volume: 165, Issue:2

    Topics: Adult; Anesthesia; Anesthetics; Brain Neoplasms; Craniotomy; Glioma; Humans; Propofol; Retrospective

2023
Is assessment of skeletal muscle mass useful to predict time-to-awake in awake craniotomies?
    Medicine, 2023, Nov-24, Volume: 102, Issue:47

    Topics: Anesthesia; Brain Neoplasms; Craniotomy; Cross-Sectional Studies; Humans; Propofol; Wakefulness

2023
The choice of anaesthesia for glioblastoma surgery does not impact the time to recurrence.
    Scientific reports, 2020, 03-27, Volume: 10, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Brain Neoplasms; Disea

2020
Anesthetic Management of Awake Craniotomy for Resection of the Language and Motor Cortex Vascular Malformations.
    World neurosurgery, 2020, Volume: 143

    Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Intravenous; Brain Neoplasms; Broca Area; Cerebr

2020
Propofol Represses Cell Growth and Metastasis by Modulating the Circular RNA Non-SMC Condensin I Complex Subunit G/MicroRNA-200a-3p/RAB5A Axis in Glioma.
    World neurosurgery, 2021, Volume: 153

    Topics: Adult; Anesthetics, Intravenous; Apoptosis; Brain Neoplasms; Cell Cycle Proteins; Cell Movement; Cel

2021
Effects of propofol on cortico-cortical evoked potentials in the dorsal language white matter pathway.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2021, Volume: 132, Issue:8

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Cerebral Cortex; Craniotomy; Evoked Potentials; Female; Hu

2021
Lung but not brain cancer cell malignancy inhibited by commonly used anesthetic propofol during surgery: Implication of reducing cancer recurrence risk.
    Journal of advanced research, 2021, Volume: 31

    Topics: A549 Cells; Anesthetics, Intravenous; Antineoplastic Agents; Brain Neoplasms; Cell Movement; Cell Pr

2021
Awake craniotomy anesthetic management using dexmedetomidine, propofol, and remifentanil.
    Drug design, development and therapy, 2017, Volume: 11

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Brain Neoplasms; Craniotomy; Dexmedetomidine; Female;

2017
Pharmacokinetics and pharmacodynamics of propofol: changes in patients with frontal brain tumours.
    British journal of anaesthesia, 2017, Jun-01, Volume: 118, Issue:6

    Topics: Adult; Algorithms; Anesthetics, Intravenous; Brain Neoplasms; Consciousness Monitors; Frontal Lobe;

2017
Genistein exerts potent antitumour effects alongside anaesthetic, propofol, by suppressing cell proliferation and nuclear factor-κB-mediated signalling and through upregulating microRNA-218 expression in an intracranial rat brain tumour model.
    The Journal of pharmacy and pharmacology, 2017, Volume: 69, Issue:11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Caspase 3; Cell

2017
ANAESTHESIA FOR AWAKE BRAIN TUMOUR SURGERY: CASE REPORT.
    Medicinski pregled, 2016, Volume: 69, Issue:9-10

    Topics: Anesthesia; Brain Neoplasms; Consciousness; Female; Humans; Propofol; Young Adult

2016
Incidence of tolerance in children undergoing repeated administration of propofol for proton radiation therapy: a retrospective study.
    BMC anesthesiology, 2018, 09-07, Volume: 18, Issue:1

    Topics: Brain Neoplasms; Child; Child, Preschool; Drug Administration Schedule; Drug Tolerance; Female; Huma

2018
Effect of Dexmedetomidine Combined Anesthesia on Motor evoked Potentials During Brain Tumor Surgery.
    World neurosurgery, 2019, Volume: 123

    Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthetics; Brain; Brain Neoplas

2019
In reply: Superior recovery profiles of propofol-based regimen as compared to isoflurane-based regimen in patients undergoing craniotomy for primary brain tumor excision: a retrospective study.
    Journal of anesthesia, 2013, Volume: 27, Issue:3

    Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Brain Neoplasms; Female; H

2013
Extubation time in neurosurgical patients: does it matter?
    Journal of anesthesia, 2013, Volume: 27, Issue:3

    Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Brain Neoplasms; Female; H

2013
Bispectral index values and propofol concentrations at loss and return of consciousness in patients with frontal brain tumours and control patients.
    British journal of anaesthesia, 2014, Volume: 112, Issue:1

    Topics: Adult; Aged; Anesthetics, Intravenous; Brain Neoplasms; Consciousness; Electroencephalography; Femal

2014
[Endotracheal intubation in an adult patient fitted with a Leksell frame using a Pentax Airwayscope with a pediatric-type INTLOCK blade (ITL-P)].
    Masui. The Japanese journal of anesthesiology, 2014, Volume: 63, Issue:8

    Topics: Adult; Anesthesia, General; Brain Neoplasms; Brain Stem; Female; Glioblastoma; Humans; Intubation, I

2014
Ammonia encephalopathy and awake craniotomy for brain language mapping: cause of failed awake craniotomy.
    Revista espanola de anestesiologia y reanimacion, 2015, Volume: 62, Issue:5

    Topics: Anesthesia, General; Anesthesia, Local; Anticonvulsants; Aphasia; Benzodiazepines; Brain Diseases; B

2015
Effects of propofol and sevoflurane on aquaporin-4 and aquaporin-9 expression in patients performed gliomas resection.
    Brain research, 2015, Oct-05, Volume: 1622

    Topics: Aquaporin 4; Aquaporins; Blotting, Western; Brain; Brain Edema; Brain Neoplasms; Female; Glioma; Hom

2015
Evidence of Resting-state Activity in Propofol-anesthetized Patients with Intracranial Tumors.
    Academic radiology, 2016, Volume: 23, Issue:2

    Topics: Adenoma; Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Auditory Cortex; Brain Mapp

2016
Seizure and Fever.
    The Journal of emergency medicine, 2016, Volume: 50, Issue:5

    Topics: Acyclovir; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antiviral Agents; Brain Neoplasms; Ceftri

2016
[Five cases of seizures during intravenous propofol anesthesia for neurosurgery].
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2009, Volume: 56, Issue:12

    Topics: Anesthetics, Intravenous; Brain Neoplasms; Humans; Middle Aged; Neurosurgical Procedures; Propofol;

2009
Cerebral blood flow, blood volume, and mean transit time responses to propofol and indomethacin in peritumor and contralateral brain regions: perioperative perfusion-weighted magnetic resonance imaging in patients with brain tumors.
    Anesthesiology, 2010, Volume: 112, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia; Anti-Inflammatory Agents, Non-Steroidal; Blood Volume; Brain; B

2010
Cerebral blood flow, blood volume, and mean transit time responses to propofol and indomethacin in peritumor and contralateral brain regions: perioperative perfusion-weighted magnetic resonance imaging in patients with brain tumors.
    Anesthesiology, 2010, Volume: 112, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia; Anti-Inflammatory Agents, Non-Steroidal; Blood Volume; Brain; B

2010
Cerebral blood flow, blood volume, and mean transit time responses to propofol and indomethacin in peritumor and contralateral brain regions: perioperative perfusion-weighted magnetic resonance imaging in patients with brain tumors.
    Anesthesiology, 2010, Volume: 112, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia; Anti-Inflammatory Agents, Non-Steroidal; Blood Volume; Brain; B

2010
Cerebral blood flow, blood volume, and mean transit time responses to propofol and indomethacin in peritumor and contralateral brain regions: perioperative perfusion-weighted magnetic resonance imaging in patients with brain tumors.
    Anesthesiology, 2010, Volume: 112, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia; Anti-Inflammatory Agents, Non-Steroidal; Blood Volume; Brain; B

2010
Analysis of propofol/remifentanil infusion protocol for tumor surgery with intraoperative brain mapping.
    Journal of neurosurgical anesthesiology, 2010, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Brain Mapping; Brain Neo

2010
Nonopioid anesthesia for awake craniotomy: a case report.
    AANA journal, 2010, Volume: 78, Issue:1

    Topics: Adult; Anesthesia; Anesthetics, Intravenous; Awareness; Brain Neoplasms; Craniotomy; Humans; Male; O

2010
Anaesthesia for awake craniotomy is safe and well-tolerated.
    Danish medical bulletin, 2010, Volume: 57, Issue:10

    Topics: Anesthesia, General; Anesthetics, Intravenous; Brain Neoplasms; Conscious Sedation; Craniotomy; Elec

2010
Increase in cerebral metabolites during induction of propofol anaesthesia.
    British journal of anaesthesia, 2012, Volume: 108, Issue:1

    Topics: Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Brain; Brain Chemistry; Brai

2012
Superior recovery profiles of propofol-based regimen as compared to isoflurane-based regimen in patients undergoing craniotomy for primary brain tumor excision: a retrospective study.
    Journal of anesthesia, 2012, Volume: 26, Issue:5

    Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Brain Neoplasms; Craniotom

2012
Accidental intraarterial drug injections via intravascular catheters placed on the dorsum of the hand.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:2

    Topics: Accidents, Traffic; Adult; Anesthetics, Intravenous; Brain Neoplasms; Catheterization, Peripheral; C

2002
[BIS monitoring is useful for reliable intraoperative cortical mapping during brain tumor operations].
    No shinkei geka. Neurological surgery, 2002, Volume: 30, Issue:11

    Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Brain Mapping; Brain Neoplasms; Cere

2002
Cerebral vascular reactivity response to anaesthetic induction with propofol in patients with intracranial space-occupying lesions and vascular malformations.
    European journal of anaesthesiology, 2003, Volume: 20, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Blood Flow Velocity; Blood Pressure; Brain Neopla

2003
[Refractory generalized convulsions in a patient undergoing brain tumor resection during propofol anesthesia].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:6

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Brain Neoplasms; Craniotomy; Epilepsy, Gen

2004
Intracarotid propofol test for speech and memory dominance in man.
    Neurology, 2004, Aug-10, Volume: 63, Issue:3

    Topics: Adolescent; Adult; Amobarbital; Brain Mapping; Brain Neoplasms; Cerebrovascular Disorders; Child; Do

2004
Comparison of conscious sedation and general anesthesia for motor mapping and resection of tumors located near motor cortex.
    Neurosurgical focus, 2003, Jul-15, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Anesthesia, General; Brain Mapping; Brain Neoplasms; Conscious Sedation; Craniotomy;

2003
Do indomethacin and propofol cause cerebral ischemic damage? Diffusion-weighted magnetic resonance imaging in patients undergoing craniotomy for brain tumors.
    Anesthesiology, 2004, Volume: 101, Issue:4

    Topics: Adult; Aged; Brain Ischemia; Brain Neoplasms; Craniotomy; Diffusion; Female; Humans; Indomethacin; M

2004
Dexmedetomidine as the primary sedative agent for brain radiation therapy in a 21-month old child.
    Paediatric anaesthesia, 2005, Volume: 15, Issue:3

    Topics: Brain Neoplasms; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant; Male; Propofol; Radiother

2005
[Intraoperative mapping of motor areas during brain tumor surgery: electrical stimulation patterns].
    Arquivos de neuro-psiquiatria, 2005, Volume: 63, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Brain Mapping; Brain Neoplasms; Child; Craniotomy

2005
Propofol attenuates responses of the auditory cortex to acoustic stimulation in a dose-dependent manner: a FMRI study.
    Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:6

    Topics: Acoustic Stimulation; Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous;

2005
A retrospective analysis of a remifentanil/propofol general anesthetic for craniotomy before awake functional brain mapping.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:2

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Brain Mapping; Brain Neoplas

2005
Postoperative hallucinations following propofol infusion in a neurosurgical patient: a diagnostic dilemma.
    Journal of neurosurgical anesthesiology, 2005, Volume: 17, Issue:3

    Topics: Aged; Anesthetics, Intravenous; Brain Neoplasms; Glioma; Hallucinations; Humans; Male; Neurosurgical

2005
Acute pancreatitis induced by short-term propofol administration.
    Paediatric anaesthesia, 2005, Volume: 15, Issue:11

    Topics: Acute Disease; Acute Kidney Injury; Anesthetics, Intravenous; Brain Neoplasms; Child; Combined Modal

2005
Use of dexmedetomidine in awake craniotomy in adolescents: report of two cases.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:3

    Topics: Adolescent; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Brain Mapping; Brain Neoplasms; Cons

2006
Prolonged propofol infusions in pregnant neurosurgical patients.
    Journal of neurosurgical anesthesiology, 2007, Volume: 19, Issue:1

    Topics: Acid-Base Equilibrium; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Brain Neoplasms; Ea

2007
Evaluation of an anaesthetic technique used in dogs undergoing craniectomy for tumour resection.
    Veterinary anaesthesia and analgesia, 2007, Volume: 34, Issue:3

    Topics: Alfentanil; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Blood

2007
Propofol and remifentanil effect-site concentrations estimated by pharmacokinetic simulation and bispectral index monitoring during craniotomy with intraoperative awakening for brain tumor resection.
    Journal of neurosurgical anesthesiology, 2007, Volume: 19, Issue:3

    Topics: Adult; Anesthesia, General; Anesthetics, Combined; Anesthetics, Intravenous; Brain Neoplasms; Comput

2007
Deep propofol sedation for vacuum-assisted bite-block immobilization in children undergoing proton radiation therapy of cranial tumors.
    Paediatric anaesthesia, 2007, Volume: 17, Issue:9

    Topics: Brain Neoplasms; Child, Preschool; Conscious Sedation; Female; Head and Neck Neoplasms; Humans; Hypn

2007
Early postoperative complications after intracranial surgery: comparison between total intravenous and balanced anesthesia.
    Journal of neurosurgical anesthesiology, 2007, Volume: 19, Issue:4

    Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, In

2007
The asleep-awake technique using propofol-remifentanil anaesthesia for awake craniotomy for cerebral tumours.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:8

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Intravenous; Brain Mapping; Brain Neoplasms; Cranioto

2008
[Lactic acidosis associated with propofol during general anaesthesia for neurosurgery].
    Annales francaises d'anesthesie et de reanimation, 2008, Volume: 27, Issue:3

    Topics: Acidosis, Lactic; Aged; Anesthesia, General; Anesthetics, Intravenous; Brain Neoplasms; Glioblastoma

2008
Brain tumors may alter the relationship between bispectral index values and propofol concentrations during induction of anesthesia.
    Journal of clinical anesthesia, 2008, Volume: 20, Issue:2

    Topics: Adult; Analysis of Variance; Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Brain Ne

2008
[Anesthetic management of a case of craniotomy using TCI of remifentanil with intraoperative monitoring of motor evoked potential].
    Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:4

    Topics: Anesthesia, Intravenous; Brain Neoplasms; Craniotomy; Evoked Potentials, Motor; Humans; Male; Middle

2008
Another use for the laryngeal mask airway.
    Anaesthesia, 1995, Volume: 50, Issue:4

    Topics: Anesthesia, Intravenous; Brain Neoplasms; Humans; Laryngeal Masks; Propofol; Stereotaxic Techniques

1995
[Use of propofol in intracranial surgery in 83 consecutive patients].
    Neuro-Chirurgie, 1994, Volume: 40, Issue:2

    Topics: Adult; Aged; Anesthesia, Intravenous; Brain Diseases; Brain Neoplasms; Female; Hemodynamics; Humans;

1994
Anaesthesia for awake craniotomy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:10

    Topics: Adult; Anesthesia, Intravenous; Awareness; Brain Mapping; Brain Neoplasms; Cerebral Cortex; Cranioto

1993
Asystole as a neurologic sign.
    Journal of neurosurgical anesthesiology, 1997, Volume: 9, Issue:1

    Topics: Adult; Anesthetics, General; Blood Loss, Surgical; Blood Transfusion; Brain Neoplasms; Cautery; Cran

1997
Anaesthetic management during awake craniotomy in a 12-year-old boy.
    Paediatric anaesthesia, 1997, Volume: 7, Issue:4

    Topics: Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Brain Neoplasms; Bupivacaine; Child

1997
Methohexital as alternative to propofol for intravenous anesthesia in children undergoing daily radiation treatment: a case report.
    Anesthesiology, 1998, Volume: 88, Issue:3

    Topics: Behavior; Brain Neoplasms; Child; Child, Preschool; Humans; Hypnotics and Sedatives; Methohexital; P

1998
Anesthesia for pediatric stereotactic radiosurgery.
    Anesthesiology, 1998, Volume: 89, Issue:1

    Topics: Adolescent; Adult; Anesthetics, Intravenous; Anesthetics, Local; Brain Neoplasms; Bupivacaine; Child

1998
The influence of anesthetic choice, PaCO2, and other factors on osmotic blood-brain barrier disruption in rats with brain tumor xenografts.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:3

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Antimetabolites, Antineoplastic; Arabino

1999
Brain mapping in sedated infants and young children with passive-functional magnetic resonance imaging.
    Pediatric neurosurgery, 1999, Volume: 30, Issue:2

    Topics: Anesthesia; Anesthetics, Intravenous; Brain Mapping; Brain Neoplasms; Cerebral Cortex; Child; Child,

1999
Is laparoscopic surgery associated with specific hemodynamic changes?
    Anesthesia and analgesia, 2000, Volume: 90, Issue:3

    Topics: Anesthetics, Intravenous; Brain Neoplasms; Humans; Jugular Veins; Oxygen; Propofol

2000
Cerebral blood volume and blood flow responses to hyperventilation in brain tumors during isoflurane or propofol anesthesia.
    Anesthesia and analgesia, 2002, Volume: 94, Issue:3

    Topics: Anesthesia; Animals; Blood Volume; Brain Neoplasms; Cerebrovascular Circulation; Hyperventilation; I

2002
[Awake craniotomy with propofol sedation and a laryngeal mask airway: a case report].
    Masui. The Japanese journal of anesthesiology, 2002, Volume: 51, Issue:5

    Topics: Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Brain Neoplasms; Craniotomy;

2002
[Hemodynamic effect of low-dose propofol in neurosurgical anesthesia with high-dose fentanyl: comparison with nitrogen monoxide].
    Minerva anestesiologica, 1991, Volume: 57, Issue:9

    Topics: Adult; Aged; Anesthesia, Intravenous; Brain Neoplasms; Female; Fentanyl; Hemodynamics; Humans; Male;

1991
[Use of propofol for long-term anesthesia in surgery of the posterior fossa].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8 Suppl

    Topics: Adult; Aged; Anesthesia; Brain Neoplasms; Cranial Fossa, Posterior; Humans; Middle Aged; Propofol; S

1989
The effects of propofol on intracranial pressure and cerebral perfusion pressure in patients with brain tumors.
    Acta anaesthesiologica Belgica, 1989, Volume: 40, Issue:2

    Topics: Adult; Aged; Anesthesia, Intravenous; Blood Pressure; Brain Neoplasms; Cerebrovascular Circulation;

1989