propofol has been researched along with Astrocytoma, Grade IV in 13 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Core modules and central genes associated with propofol and sevoflurane anesthesia were identified by weighted gene coexpression network analysis (WGCNA) and establish a risk score prognostic model." | 8.31 | Co-expression prognostic-related genes signature base on propofol and sevoflurane anesthesia predict prognosis and immunotherapy response in glioblastoma. ( Hou, Z; Hui, Q; Lin, X; Luo, D; Luo, H; Xu, Y; Xu, Z, 2023) |
| "Temozolomide (TMZ) is the first-line drug for the clinical treatment of glioblastoma (GBM), but drug resistance limits its treatment benefits." | 8.12 | Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression. ( Yun, K; Zhao, W, 2022) |
| "In this limited sample size, we observed that propofol anesthesia was associated with improved survival and less postoperative recurrence in glioblastoma surgery than desflurane anesthesia." | 8.02 | Propofol-based total intravenous anesthesia is associated with better survival than desflurane anesthesia in glioblastoma surgery. ( Cheng, KI; Huang, YH; Lai, HC; Lee, MS; Lou, YS; Wu, KL; Wu, ZF, 2021) |
| " Core modules and central genes associated with propofol and sevoflurane anesthesia were identified by weighted gene coexpression network analysis (WGCNA) and establish a risk score prognostic model." | 4.31 | Co-expression prognostic-related genes signature base on propofol and sevoflurane anesthesia predict prognosis and immunotherapy response in glioblastoma. ( Hou, Z; Hui, Q; Lin, X; Luo, D; Luo, H; Xu, Y; Xu, Z, 2023) |
| "Temozolomide (TMZ) is the first-line drug for the clinical treatment of glioblastoma (GBM), but drug resistance limits its treatment benefits." | 4.12 | Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression. ( Yun, K; Zhao, W, 2022) |
| "In this limited sample size, we observed that propofol anesthesia was associated with improved survival and less postoperative recurrence in glioblastoma surgery than desflurane anesthesia." | 4.02 | Propofol-based total intravenous anesthesia is associated with better survival than desflurane anesthesia in glioblastoma surgery. ( Cheng, KI; Huang, YH; Lai, HC; Lee, MS; Lou, YS; Wu, KL; Wu, ZF, 2021) |
| " The aim of this study was to evaluate a potential influence of the anaesthetic method (inhaled anaesthetics versus total-intravenous anaesthesia using propofol) on recurrence-free and overall survival in glioblastoma patients." | 3.96 | The choice of anaesthesia for glioblastoma surgery does not impact the time to recurrence. ( Annecke, T; Grau, SJ; Hampl, J; Löhr, M; Schwab, SG; Taurisano, V; Timmer, M; Trautner, H, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 5 (38.46) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, W | 1 |
| Yun, K | 1 |
| Hou, Z | 1 |
| Luo, D | 1 |
| Luo, H | 1 |
| Hui, Q | 1 |
| Xu, Y | 1 |
| Lin, X | 1 |
| Xu, Z | 1 |
| Nizar, R | 1 |
| Cazacu, S | 1 |
| Xiang, C | 1 |
| Krasner, M | 1 |
| Barbiro-Michaely, E | 1 |
| Gerber, D | 1 |
| Schwartz, J | 1 |
| Fried, I | 1 |
| Yuval, S | 1 |
| Brodie, A | 1 |
| Kazimirsky, G | 1 |
| Amos, N | 1 |
| Unger, R | 1 |
| Brown, S | 1 |
| Rogers, L | 1 |
| Penning, DH | 1 |
| Brodie, C | 1 |
| Grau, SJ | 1 |
| Löhr, M | 1 |
| Taurisano, V | 1 |
| Trautner, H | 1 |
| Timmer, M | 1 |
| Schwab, SG | 1 |
| Hampl, J | 1 |
| Annecke, T | 1 |
| Huang, YH | 1 |
| Wu, ZF | 1 |
| Lee, MS | 1 |
| Lou, YS | 1 |
| Wu, KL | 1 |
| Cheng, KI | 1 |
| Lai, HC | 1 |
| Hsu, SS | 1 |
| Jan, CR | 2 |
| Liang, WZ | 2 |
| Takeuchi, R | 1 |
| Hoshijima, H | 1 |
| Horikoshi, Y | 1 |
| Nakamura, C | 1 |
| Iwase, Y | 1 |
| Nagasaka, H | 1 |
| Babateen, O | 1 |
| Jin, Z | 1 |
| Bhandage, A | 1 |
| Korol, SV | 1 |
| Westermark, B | 1 |
| Forsberg Nilsson, K | 1 |
| Uhrbom, L | 1 |
| Smits, A | 1 |
| Birnir, B | 1 |
| Xu, J | 1 |
| Xu, W | 1 |
| Zhu, J | 1 |
| Lu, CH | 1 |
| Bordes, J | 1 |
| Meaudre, E | 1 |
| Asencio, Y | 1 |
| Montcriol, A | 1 |
| Kaiser, E | 1 |
| Crespo, ML | 1 |
| Giménez, A | 1 |
| Bas, T | 1 |
| García, C | 1 |
| Puertes, IR | 1 |
| Viña, JR | 1 |
| Tyler, DS | 1 |
| Bacon, D | 1 |
| Mahendru, V | 1 |
| Lema, MJ | 1 |
1 trial available for propofol and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Effect of nitrous oxide and propofol on amino acid metabolism in neoplasic patients.
Topics: Amino Acids; Anesthetics, Inhalation; Anesthetics, Intravenous; Bronchial Neoplasms; Fractures, Bone | 1997 |
12 other studies available for propofol and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Propofol enhances the sensitivity of glioblastoma cells to temozolomide by inhibiting macrophage activation in tumor microenvironment to down-regulate HIF-1α expression.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Cyclooxygenase 2; Dru | 2022 |
Co-expression prognostic-related genes signature base on propofol and sevoflurane anesthesia predict prognosis and immunotherapy response in glioblastoma.
Topics: Anesthesia; Glioblastoma; Humans; Immunotherapy; Prognosis; Propofol; Sevoflurane | 2023 |
Propofol Inhibits Glioma Stem Cell Growth and Migration and Their Interaction with Microglia via BDNF-AS and Extracellular Vesicles.
Topics: Brain Neoplasms; Brain-Derived Neurotrophic Factor; Extracellular Vesicles; Glioblastoma; Glioma; Hu | 2023 |
The choice of anaesthesia for glioblastoma surgery does not impact the time to recurrence.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Brain Neoplasms; Disea | 2020 |
Propofol-based total intravenous anesthesia is associated with better survival than desflurane anesthesia in glioblastoma surgery.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2021 |
Evaluation of cytotoxicity of propofol and its related mechanism in glioblastoma cells and astrocytes.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents; Antioxidants; Apopt | 2017 |
[Endotracheal intubation in an adult patient fitted with a Leksell frame using a Pentax Airwayscope with a pediatric-type INTLOCK blade (ITL-P)].
Topics: Adult; Anesthesia, General; Brain Neoplasms; Brain Stem; Female; Glioblastoma; Humans; Intubation, I | 2014 |
Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from human glioblastoma.
Topics: Anesthetics, General; Cell Line, Tumor; Diazepam; Drug Synergism; Electrophysiological Phenomena; Et | 2015 |
Propofol suppresses proliferation and invasion of glioma cells by upregulating microRNA-218 expression.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulatio | 2015 |
Investigation of 2,6-diisopropylphenol (propofol)-evoked Ca2+ movement and cell death in human glioblastoma cells.
Topics: Anesthetics, Intravenous; Apoptosis; Calcium; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum | 2012 |
[Lactic acidosis associated with propofol during general anaesthesia for neurosurgery].
Topics: Acidosis, Lactic; Aged; Anesthesia, General; Anesthetics, Intravenous; Brain Neoplasms; Glioblastoma | 2008 |
Asystole as a neurologic sign.
Topics: Adult; Anesthetics, General; Blood Loss, Surgical; Blood Transfusion; Brain Neoplasms; Cautery; Cran | 1997 |