Page last updated: 2024-11-03

propofol and Arrhythmias, Cardiac

propofol has been researched along with Arrhythmias, Cardiac in 79 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

Research Excerpts

ExcerptRelevanceReference
" Compared to earlier case reports in the literature, recently published cases describe older patients developing PRIS at lower doses of propofol, in whom arrhythmia, hypertriglyceridaemia and fever are less frequently seen, with survival more likely."8.91Propofol infusion syndrome: a structured review of experimental studies and 153 published case reports. ( Anděl, M; Duška, F; Krajčová, A; Waldauf, P, 2015)
" Keywords were propofol, propofol infusion syndrome (PRIS), rhabdomyolysis, heart failure, arrhythmias, metabolic acidosis, brain injury, sedation, intensive care."8.86[Propofol infusion syndrome]. ( Greff, B; Laquay, N; Meyer, P; Orliaguet, G; Prieur, S, 2010)
"Propofol infusion syndrome (PIS) is defined by arrhythmia, rhabdomyolysis, lactic acidosis, and unrecognized leads to death."7.80Propofol infusion syndrome: a lethal condition in critically injured patients eliminated by a simple screening protocol. ( Clement, LP; Croce, MA; Fabian, TC; Fischer, PE; Lee, M; Magnotti, LJ; Schroeppel, TJ; Sharpe, JP, 2014)
"A hypothetical clinical vignette was created to give a classic presentation of propofol-related infusion syndrome."7.79Propofol-related infusion syndrome: role of propofol in medical complications of sedated critical care patients. ( Imam, TH, 2013)
"The authors' results suggest that propofol preserves connexin 43 phosphorylation during acute myocardial ischemia, as compared with sevoflurane, and this might protect the heart from serious ventricular arrhythmias during acute coronary occlusion."7.75Differential effects of propofol and sevoflurane on ischemia-induced ventricular arrhythmias and phosphorylated connexin 43 protein in rats. ( Hirata, N; Kamada, N; Kanaya, N; Kimura, S; Namiki, A, 2009)
" Future controlled studies focusing on evaluating whether propofol manifests the derangements of critical illness more frequently than other sedatives will need to be large."7.75Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter study. ( Anger, KE; Arpino, PA; Barletta, JF; Devlin, JW; Fong, JJ; Gerlach, AT; Grgurich, P; Kendall, E; Kuper, PJ; Papadopoulos, S; Roberts, RJ; Ruthazer, R; Schumaker, G; Szumita, PM; Voils, SA; Xamplas, R; Yogaratnam, D, 2009)
"The propofol infusion syndrome is a rare but potentially lethal complication resulting from a prolonged continuous administration of propofol."7.73[Propofol infusion syndrome]. ( Jost, R; Likar, R; Oher, M; Pointner, I; Schalk, HV; Trampitsch, E, 2006)
"In isolated guinea pig ventricular myocardium propofol, but not Intralipid(R), attenuated the ischemia-induced shortening of action potential and, thus, the dispersion of repolarization and decreased the occurrence of spontaneous ventricular arrhythmia related to reperfusion injury."7.72Propofol decreases reperfusion-induced arrhythmias in a model of "border zone" between normal and ischemic-reperfused guinea pig myocardium. ( Bricard, H; Ducouret, P; Flais, F; Gérard, JL; Hanouz, JL; Rouet, R; Yvon, A, 2003)
"Propofol in this model was more arrhythmogenic than thiopental, as manifested by a longer duration of induced arrhythmias, particularly AFI."7.72Comparative effects of thiopental and propofol on atrial vulnerability: electrophysiological study in a porcine model including acute alcoholic intoxication. ( Almendral, J; Anadón, MJ; González, P; Navia, J; Zaballos, M, 2004)
" Arrhythmogenic effects of propafenone (pro-arrhythmia) were verified in 50% of group II."7.72Effects of propafenone associated with propofol on myocardial contractility, heart rate, coronary flow, and the incidence of arrhythmia in isolated hearts of rats. ( Assis, NL; do Valle, GG; Garcia, SL; Gomes, OM, 2004)
"Although propofol is a widely used intravenous anesthetic, its effect on epinephrine-induced arrhythmias remains unknown."7.68Enhancement by propofol of epinephrine-induced arrhythmias in dogs. ( Hayashi, Y; Kamibayashi, T; Kawabata, K; Sumikawa, K; Yamatodani, A; Yoshiya, I, 1991)
"A case is presented in which asystole and convulsions occurred after an attempted induction of anaesthesia with propofol and fentanyl."7.67Asystole with convulsion following a subanesthetic dose of propofol plus fentanyl. ( Dorrington, KL, 1989)
"Propofol sedation has a similar risk of cardiopulmonary adverse events compared with traditional agents for gastrointestinal endoscopic procedures."6.55Similar Risk of Cardiopulmonary Adverse Events Between Propofol and Traditional Anesthesia for Gastrointestinal Endoscopy: A Systematic Review and Meta-analysis. ( Garg, S; Issa, D; Lopez, R; Sanaka, MR; Vargo, JJ; Wadhwa, V, 2017)
"Propofol displays both pro- and anti-arrhythmic effects in a concentration-dependent manner."6.47Propofol and arrhythmias: two sides of the coin. ( Chen, R; Hong, J; Kong, AL; Liu, Q; Liu, SW; Qian, C; Song, LS; Sun, BG; Wang, LX, 2011)
"Propofol has gained popularity for its rapid onset and rapid recovery even after prolonged use, and for the neuroprotection conferred."6.44Propofol infusion syndrome: an overview of a perplexing disease. ( Fodale, V; La Monaca, E, 2008)
" Isolated perfused newborn mouse hearts were exposed to a toxic dose of propofol or intralipid for 30-min."5.72Modeling propofol-induced cardiotoxicity in the isolated-perfused newborn mouse heart. ( Barajas, MB; Griffiths, KK; Levy, RJ; Sun, L; Wang, A; Yang, G, 2022)
"Propofol was utilized as part of the anesthetic protocol."5.48Propofol infusion-like syndrome in a dog. ( Mallard, JM; Peterson, NW; Rieser, TM, 2018)
"PRIS causing hyperkalemia is a well-known clinical entity."5.43Propofol Induced Hyperkalemia and Its Management in End Stage Renal Disease Patients. ( El-Ali, IM; Onuchic, A; Trivedi, RD; Virmani, S, 2016)
" No adverse events were noticed during the recovery phase."5.39Safe single-dose administration of propofol in patients with established Brugada syndrome: a retrospective database analysis. ( Beckers, S; Bhutia, JT; Brugada, P; Casado-Arroyo, R; Chierchia, GB; Conte, G; De Asmundis, C; Flamée, P; Poelaert, J; Sarkozy, A; Umbrain, V; Van Malderen, S; Verborgh, C, 2013)
"Propofol is a potent and widely used central-acting sedative drug."5.35Propofol infusion syndrome with arrhythmia, myocardial fat accumulation and cardiac failure. ( Jorens, PG; Van den Eynden, GG, 2009)
" Compared to earlier case reports in the literature, recently published cases describe older patients developing PRIS at lower doses of propofol, in whom arrhythmia, hypertriglyceridaemia and fever are less frequently seen, with survival more likely."4.91Propofol infusion syndrome: a structured review of experimental studies and 153 published case reports. ( Anděl, M; Duška, F; Krajčová, A; Waldauf, P, 2015)
", hypoxia, hypotension, arrhythmia, and apnea) and sedation profiles were assessed."4.89The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis. ( Chen, C; Chen, J; Deng, D; Liu, J; Long, A; Tang, D; Wang, D; Wang, L; Xu, Y; Zhu, Z, 2013)
" Keywords were propofol, propofol infusion syndrome (PRIS), rhabdomyolysis, heart failure, arrhythmias, metabolic acidosis, brain injury, sedation, intensive care."4.86[Propofol infusion syndrome]. ( Greff, B; Laquay, N; Meyer, P; Orliaguet, G; Prieur, S, 2010)
" The following 4 cardiopulmonary complications were assessed: hypoxia, hypotension, arrhythmias, and apnea."4.82Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis. ( Khandwala, F; Lopez, R; Qadeer, MA; Vargo, JJ; Zuccaro, G, 2005)
"Arrhythmias, Cardiac ischemia, Cardiovascular toxicity, Propofol."3.88Propofol: a safe anaesthetic drug in experimental cardiac surgery in rabbits. ( Barbieri, A; Farinetti, A; Giuliani, E; Manenti, A; Mattioli, AV, 2018)
"Propofol infusion syndrome (PIS) is defined by arrhythmia, rhabdomyolysis, lactic acidosis, and unrecognized leads to death."3.80Propofol infusion syndrome: a lethal condition in critically injured patients eliminated by a simple screening protocol. ( Clement, LP; Croce, MA; Fabian, TC; Fischer, PE; Lee, M; Magnotti, LJ; Schroeppel, TJ; Sharpe, JP, 2014)
"A hypothetical clinical vignette was created to give a classic presentation of propofol-related infusion syndrome."3.79Propofol-related infusion syndrome: role of propofol in medical complications of sedated critical care patients. ( Imam, TH, 2013)
" Future controlled studies focusing on evaluating whether propofol manifests the derangements of critical illness more frequently than other sedatives will need to be large."3.75Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter study. ( Anger, KE; Arpino, PA; Barletta, JF; Devlin, JW; Fong, JJ; Gerlach, AT; Grgurich, P; Kendall, E; Kuper, PJ; Papadopoulos, S; Roberts, RJ; Ruthazer, R; Schumaker, G; Szumita, PM; Voils, SA; Xamplas, R; Yogaratnam, D, 2009)
"The authors' results suggest that propofol preserves connexin 43 phosphorylation during acute myocardial ischemia, as compared with sevoflurane, and this might protect the heart from serious ventricular arrhythmias during acute coronary occlusion."3.75Differential effects of propofol and sevoflurane on ischemia-induced ventricular arrhythmias and phosphorylated connexin 43 protein in rats. ( Hirata, N; Kamada, N; Kanaya, N; Kimura, S; Namiki, A, 2009)
"Propofol infusion syndrome, characterised by cardiovascular collapse, metabolic acidosis, hepatomegaly, renal failure and rhabdomyolysis, is a rare and often fatal syndrome seen in critically ill children undergoing long-term propofol sedation."3.73[Propofol infusion syndrome in children]. ( Hansen, TG, 2005)
"The propofol infusion syndrome is a rare but potentially lethal complication resulting from a prolonged continuous administration of propofol."3.73[Propofol infusion syndrome]. ( Jost, R; Likar, R; Oher, M; Pointner, I; Schalk, HV; Trampitsch, E, 2006)
"In isolated guinea pig ventricular myocardium propofol, but not Intralipid(R), attenuated the ischemia-induced shortening of action potential and, thus, the dispersion of repolarization and decreased the occurrence of spontaneous ventricular arrhythmia related to reperfusion injury."3.72Propofol decreases reperfusion-induced arrhythmias in a model of "border zone" between normal and ischemic-reperfused guinea pig myocardium. ( Bricard, H; Ducouret, P; Flais, F; Gérard, JL; Hanouz, JL; Rouet, R; Yvon, A, 2003)
" Arrhythmogenic effects of propafenone (pro-arrhythmia) were verified in 50% of group II."3.72Effects of propafenone associated with propofol on myocardial contractility, heart rate, coronary flow, and the incidence of arrhythmia in isolated hearts of rats. ( Assis, NL; do Valle, GG; Garcia, SL; Gomes, OM, 2004)
"Propofol in this model was more arrhythmogenic than thiopental, as manifested by a longer duration of induced arrhythmias, particularly AFI."3.72Comparative effects of thiopental and propofol on atrial vulnerability: electrophysiological study in a porcine model including acute alcoholic intoxication. ( Almendral, J; Anadón, MJ; González, P; Navia, J; Zaballos, M, 2004)
"Halothane more so than isoflurane potentiates an alpha1-adrenoceptor (alpha1-AR)-mediated action of epinephrine that abnormally slows conduction in Purkinje fibers and may facilitate reentrant arrhythmias."3.70Multiple agents potentiate alpha1-adrenoceptor-induced conduction depression in canine cardiac purkinje fibers. ( Bosnjak, ZJ; Contney, S; Kulier, AH; Lathrop, DA; Turner, LA; Vodanovic, S, 2000)
"Propofol ensures a calm and rapid induction of anaesthesia in case of planned cardioversion for supraventricular arrhythmia."3.69[Use of Diprivan in cardioversion and interventional cardiology]. ( Samain, E, 1994)
"Although propofol is a widely used intravenous anesthetic, its effect on epinephrine-induced arrhythmias remains unknown."3.68Enhancement by propofol of epinephrine-induced arrhythmias in dogs. ( Hayashi, Y; Kamibayashi, T; Kawabata, K; Sumikawa, K; Yamatodani, A; Yoshiya, I, 1991)
"A case is presented in which asystole and convulsions occurred after an attempted induction of anaesthesia with propofol and fentanyl."3.67Asystole with convulsion following a subanesthetic dose of propofol plus fentanyl. ( Dorrington, KL, 1989)
"However, the number of arrhythmias recorded was low in most cases (less than 10 supraventricular extrasystoles and less than 100 ventricular extrasystoles)."2.71Incidence of post-anaesthetic arrhythmias in dogs. ( Buhl, K; Fedrowitz, M; Kersten, U; Kramer, S; Mischke, R; Nolte, I, 2005)
"The total incidence of major arrhythmias was 10 % and the incidence of minor arrhythmias was 62 %."2.71Sedation for fiberoptic bronchoscopy: fewer adverse cardiovascular effects with propofol than with midazolam. ( Cakan, A; Deren, S; Gülerçe, G; Olgaç, G; Ozsöz, A; Oztürk, T, 2004)
"In most recordings, no ventricular arrhythmias were detected, the maximum frequency being two VPCs/24 h."2.7024-hour Holter-monitoring in the perianaesthetic period in dogs premedicated with dexmedetomidine. ( Hietanen, H; Huttula, J; Kuusela, E; Raekallio, M; Vainio, O, 2002)
"The incidence of cardiac dysrhythmias was similar in the study groups."2.70QT interval and QT dispersion during the induction of anaesthesia in patients with subarachnoid haemorrhage: a comparison of thiopental and propofol. ( Kyttä, JV; Randell, TT; Tanskanen, PE, 2002)
"No cardiac arrhythmias occurred in either of the groups."2.69Effect of esmolol on the hemodynamic and electrocardiographic changes during laryngomicroscopy under propofol-alfentanil anesthesia. ( Korpinen, R; Saarnivaara, L; Simola, M, 1998)
"Cardiac dysrhythmias were few regardless of the induction method."2.69Induction characteristics of thiopentone/suxamethonium, propofol/alfentanil or halothane alone in children aged 1-3 years. ( Annila, P; Baer, G; Lindgren, L; Reinikainen, P; Viitanen, H, 1999)
"Propofol was associated with hypotension and a higher incidence of apnea, and its duration of action was similar to that of etomidate or thiopental."2.67Anesthesia for elective cardioversion: a comparison of four anesthetic agents. ( Canessa, R; Concha, M; Dagnino, J; Lema, G; Urzúa, J, 1991)
"Propofol was associated with a more rapid emergence from anaesthesia than thiopentone."2.66Propofol vs thiopentone as anaesthetic agents for short operative procedures. ( Carlsson, P; Hägerdal, M; Hallén, B; Henriksson, BA; Lundberg, D; Pontén, J, 1987)
"All tachyarrhythmias that occurred in the atria and ventricles were analyzed."2.58Does dexmedetomidine have an antiarrhythmic effect on cardiac patients? A meta-analysis of randomized controlled trials. ( Ling, X; Ni, Y; Wu, C; Zhang, C; Zhou, H; Zhu, Z, 2018)
"Propofol sedation has a similar risk of cardiopulmonary adverse events compared with traditional agents for gastrointestinal endoscopic procedures."2.55Similar Risk of Cardiopulmonary Adverse Events Between Propofol and Traditional Anesthesia for Gastrointestinal Endoscopy: A Systematic Review and Meta-analysis. ( Garg, S; Issa, D; Lopez, R; Sanaka, MR; Vargo, JJ; Wadhwa, V, 2017)
"Propofol displays both pro- and anti-arrhythmic effects in a concentration-dependent manner."2.47Propofol and arrhythmias: two sides of the coin. ( Chen, R; Hong, J; Kong, AL; Liu, Q; Liu, SW; Qian, C; Song, LS; Sun, BG; Wang, LX, 2011)
"Propofol has gained popularity for its rapid onset and rapid recovery even after prolonged use, and for the neuroprotection conferred."2.44Propofol infusion syndrome: an overview of a perplexing disease. ( Fodale, V; La Monaca, E, 2008)
"In the cat the arrhythmia threshold to adrenaline was greater than that in cats anaesthetized with halothane and no ganglion blocking or alpha-adrenoceptor antagonist properties were demonstrated."2.37Interaction studies and other investigations of the pharmacology of propofol ('Diprivan'). ( Blackburn, TP; Glen, JB; Hunter, SC; Wood, P, 1985)
" Isolated perfused newborn mouse hearts were exposed to a toxic dose of propofol or intralipid for 30-min."1.72Modeling propofol-induced cardiotoxicity in the isolated-perfused newborn mouse heart. ( Barajas, MB; Griffiths, KK; Levy, RJ; Sun, L; Wang, A; Yang, G, 2022)
"Propofol is a most commonly used anaesthetic drug for conscious sedation in outpatient procedures."1.56The effect of propofol on frontal QRS-T angle in patients undergoing elective colonoscopy procedure. ( Altiparmak, HI; Bayram, G; Besli, F; Bicer Yesilay, A; Demir, K; Gungoren, F; Tanriverdi, Z; Tascanov, MB, 2020)
"Propofol was utilized as part of the anesthetic protocol."1.48Propofol infusion-like syndrome in a dog. ( Mallard, JM; Peterson, NW; Rieser, TM, 2018)
"PRIS causing hyperkalemia is a well-known clinical entity."1.43Propofol Induced Hyperkalemia and Its Management in End Stage Renal Disease Patients. ( El-Ali, IM; Onuchic, A; Trivedi, RD; Virmani, S, 2016)
"Intraoperative cardiac dysrhythmias and perioperative and postoperative complications were recorded."1.42Cardiac Dysrhythmias in Children Undergoing Extracorporeal Shock Wave Lithotripsy Under General Anesthesia or Propofol Sedation: A Prospective, Observational Cohort Study. ( Harding, L; Hume-Smith, H; Mathers, J; Smeulders, N; Solar, BT, 2015)
"Cardiac arrhythmias were observed in 21 (53·8%) dogs."1.40Management and complications of anaesthesia during balloon valvuloplasty for pulmonic stenosis in dogs: 39 cases (2000 to 2012). ( Monteiro-Steagall, BP; Ramos, RV; Steagall, PV, 2014)
"Many emergency patients present with cardiac arrhythmias requiring emergency direct current countershock cardioversion (DCCV) as a part of their management."1.40Procedural sedation with propofol for emergency DC cardioversion. ( Govier, M; Kaye, P, 2014)
" No adverse events were noticed during the recovery phase."1.39Safe single-dose administration of propofol in patients with established Brugada syndrome: a retrospective database analysis. ( Beckers, S; Bhutia, JT; Brugada, P; Casado-Arroyo, R; Chierchia, GB; Conte, G; De Asmundis, C; Flamée, P; Poelaert, J; Sarkozy, A; Umbrain, V; Van Malderen, S; Verborgh, C, 2013)
" Cardiac and respiratory events are generally minor, and MAC can be considered a safe option for most ERCP patients."1.37A prospective assessment of sedation-related adverse events and patient and endoscopist satisfaction in ERCP with anesthesiologist-administered sedation. ( Barnett, SR; Berzin, TM; Chuttani, R; Jakubowski, M; Pleskow, DK; Sanaka, S; Sawhney, MS; Sepe, PS; Sundar, E, 2011)
"This process has been shown to ablate tumors in animal studies."1.36Irreversible electroporation: a new challenge in "out of operating theater" anesthesia. ( Ball, C; Kavnoudias, H; Thomson, KR, 2010)
"Propofol is a potent and widely used central-acting sedative drug."1.35Propofol infusion syndrome with arrhythmia, myocardial fat accumulation and cardiac failure. ( Jorens, PG; Van den Eynden, GG, 2009)
"Significant arrhythmias were observed in 9 dogs in the postoperative period, 5 of which were in group I and 4 in group II."1.34Prevalence of perioperative arrhythmias in 50 young, healthy dogs. ( Carr, AP; Duerr, FM; Duke, T; Monnet, E; Shmon, CL, 2007)
"Nine patients (6%) with infantile-onset Pompe disease experienced an arrhythmia or cardiopulmonary arrest soon after the induction of general anesthesia."1.34Cardiac arrhythmias following anesthesia induction in infantile-onset Pompe disease: a case series. ( Corzo, D; Dearmey, SM; Kishnani, PS; Li, JS; Mackey, JF; Morgan, C; Ross, AK; Wang, LY; Worden, M, 2007)
"The recorded number of arrhythmias was low and no statistical difference was demonstrated between the 2 patient groups."1.32[Comparison of the influence of different anesthetic protocols in the development of post-anesthetic arrhythmia in the dog]. ( Buhl, K; Fedrowitz, M; Kersten, U; Kramer, S; Mischke, R; Nolte, I, 2003)
"Propofol was stopped."1.32A case of propofol toxicity: further evidence for a causal mechanism. ( Al Ayed, T; Decell, MK; Withington, DE, 2004)
"The patient developed cardiac arrhythmia, metabolic acidosis, and cardiac failure, which resulted in death."1.31Death related to propofol use in an adult patient. ( Baerga-Varela, Y; Murray, MJ; Perrier, ND, 2000)
"Bupivacaine was infused at a constant rate of 2 mg x kg(-1) x min(-1) while electrocardiogram, electroencephalogram, and invasive arterial pressure were continuously monitored."1.30A comparison of the effects of propofol and sevoflurane on the systemic toxicity of intravenous bupivacaine in rats. ( Kobayashi, T; Ohmura, S; Ohta, T; Yamamoto, K, 1999)
"Propofol was infused to achieve deep sedation during induced ventricular fibrillation and later cardioversion for testing the devices."1.30[Anesthetic management for implantation of implantable cardioverter-defibrillators]. ( Hara, M; Kurita, T; Kuro, M; Uchida, O, 1999)
"Propofol was found to give a rapid, smooth induction with wide variation in dose requirement (0."1.27Total intravenous anaesthesia using propofol infusion--50 consecutive cases. ( Galletly, DC; Short, TG, 1988)

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-19906 (7.59)18.7374
1990's12 (15.19)18.2507
2000's30 (37.97)29.6817
2010's28 (35.44)24.3611
2020's3 (3.80)2.80

Authors

AuthorsStudies
Barajas, MB1
Wang, A1
Griffiths, KK1
Sun, L1
Yang, G1
Levy, RJ1
Tascanov, MB1
Tanriverdi, Z1
Gungoren, F1
Besli, F1
Bicer Yesilay, A1
Altiparmak, HI1
Bayram, G1
Demir, K1
Kohli, U1
Charbit, B1
Ling, X1
Zhou, H1
Ni, Y1
Wu, C1
Zhang, C1
Zhu, Z2
Giuliani, E1
Manenti, A1
Barbieri, A1
Farinetti, A1
Mattioli, AV1
Wiemer, HM1
Butler, MB1
Froese, PC1
Lapierre, A1
Carriere, C1
Etsell, GR1
Farina, D1
Jones, J1
Murray, J1
Campbell, SG1
Virmani, S1
Onuchic, A1
El-Ali, IM1
Trivedi, RD1
Mallard, JM1
Rieser, TM1
Peterson, NW1
Imam, TH1
Schroeppel, TJ1
Fabian, TC1
Clement, LP1
Fischer, PE1
Magnotti, LJ1
Sharpe, JP1
Lee, M1
Croce, MA1
Savard, M3
Dupré, N1
Turgeon, AF3
Desbiens, R1
Langevin, S1
Brunet, D1
Kaye, P1
Govier, M1
Flamée, P1
De Asmundis, C1
Bhutia, JT1
Conte, G1
Beckers, S1
Umbrain, V1
Verborgh, C1
Chierchia, GB1
Van Malderen, S1
Casado-Arroyo, R1
Sarkozy, A1
Brugada, P1
Poelaert, J1
Ramos, RV1
Monteiro-Steagall, BP1
Steagall, PV1
Parness, J1
Kim, SY1
Song, MK1
Kim, MS1
Kim, EH1
Han, DW1
Mathers, J1
Solar, BT1
Harding, L1
Smeulders, N1
Hume-Smith, H1
Krajčová, A1
Waldauf, P1
Anděl, M1
Duška, F1
Wadhwa, V1
Issa, D1
Garg, S1
Lopez, R2
Sanaka, MR1
Vargo, JJ2
Zaccheo, MM1
Bucher, DH1
Hirata, N1
Kanaya, N1
Kamada, N1
Kimura, S1
Namiki, A1
Chatzidaki, R1
Koraki, E1
Vasiliadis, K1
Aslanidis, T1
Vasilakos, D1
Jeanne, M1
Logier, R1
De Jonckheere, J1
Tavernier, B1
Siracusano, L1
Girasole, V1
Jorens, PG1
Van den Eynden, GG1
Roberts, RJ1
Barletta, JF1
Fong, JJ1
Schumaker, G1
Kuper, PJ1
Papadopoulos, S1
Yogaratnam, D1
Kendall, E1
Xamplas, R1
Gerlach, AT1
Szumita, PM1
Anger, KE1
Arpino, PA1
Voils, SA1
Grgurich, P1
Ruthazer, R1
Devlin, JW1
Ball, C1
Thomson, KR1
Kavnoudias, H1
Laquay, N1
Prieur, S1
Greff, B1
Meyer, P1
Orliaguet, G1
Hanci, V1
Aydin, M1
Yurtlu, BS1
Ayoğlu, H1
Okyay, RD1
Taş, E1
Erdoğan, G1
Aydoğan, K1
Turan, IO1
Fernández, AB1
Fernández, J1
Berzin, TM1
Sanaka, S1
Barnett, SR1
Sundar, E1
Sepe, PS1
Jakubowski, M1
Pleskow, DK1
Chuttani, R1
Sawhney, MS1
Hellström, J1
Öwall, A1
Bergström, J1
Sackey, PV1
Amrein, S1
Amrein, K1
Amegah-Sakotnik, A1
Reist, U1
Ensner, R1
Liu, Q1
Kong, AL1
Chen, R1
Qian, C1
Liu, SW1
Sun, BG1
Wang, LX1
Song, LS1
Hong, J1
Oji, M1
Terao, Y1
Toyoda, T1
Kuriyama, T1
Miura, K1
Fukusaki, M1
Sumikawa, K2
Wang, D1
Chen, C1
Chen, J2
Xu, Y1
Wang, L1
Deng, D1
Long, A1
Tang, D1
Liu, J1
Tanskanen, PE1
Kyttä, JV1
Randell, TT1
Kuusela, E1
Raekallio, M1
Hietanen, H1
Huttula, J1
Vainio, O1
Hanouz, JL1
Yvon, A1
Flais, F1
Rouet, R1
Ducouret, P1
Bricard, H1
Gérard, JL1
Buhl, K2
Kersten, U2
Kramer, S2
Mischke, R2
Fedrowitz, M2
Nolte, I2
Assis, NL1
Gomes, OM1
Garcia, SL1
do Valle, GG1
Withington, DE1
Decell, MK1
Al Ayed, T1
Zaballos, M1
Almendral, J1
Anadón, MJ1
González, P1
Navia, J1
Pleym, H1
Stenseth, R1
Wiseth, R1
Karevold, A1
Dale, O1
Oztürk, T1
Cakan, A1
Gülerçe, G1
Olgaç, G1
Deren, S1
Ozsöz, A1
Hansen, TG1
Qadeer, MA1
Khandwala, F1
Zuccaro, G1
Hermanns, H1
Lipfert, P1
Ladda, S1
Stevens, MF1
Trampitsch, E1
Oher, M1
Pointner, I1
Likar, R1
Jost, R1
Schalk, HV1
Duerr, FM1
Carr, AP1
Duke, T1
Shmon, CL1
Monnet, E1
Wang, LY1
Ross, AK1
Li, JS1
Dearmey, SM1
Mackey, JF1
Worden, M1
Corzo, D1
Morgan, C1
Kishnani, PS1
Jakobsen, CJ1
Berg, H1
Hindsholm, KB1
Faddy, N1
Sloth, E1
Akcaboy, ZN1
Akcaboy, EY1
Altinoren, B1
Karabulut, E1
Gogus, N1
Fodale, V1
La Monaca, E1
Samain, E1
Ewah, B1
Carr, C1
Neff, SP1
Futter, ME1
Anderson, BJ1
Pollock, AN1
McKenzie, AJ1
Hodges, M1
Snoeck, MM1
Korpinen, R1
Simola, M1
Saarnivaara, L1
Ohmura, S1
Ohta, T1
Yamamoto, K1
Kobayashi, T1
Lehmann, A1
Boldt, J1
Zeitler, C1
Thaler, E1
Werling, C1
Moerman, A1
Herregods, L1
Tavernier, R1
Jordaens, L1
Struys, M1
Rolly, G1
Annila, P1
Viitanen, H1
Reinikainen, P1
Baer, G1
Lindgren, L1
Hara, M1
Uchida, O1
Kuro, M1
Kurita, T1
Kulier, AH1
Turner, LA1
Vodanovic, S1
Contney, S1
Lathrop, DA1
Bosnjak, ZJ1
Perrier, ND1
Baerga-Varela, Y1
Murray, MJ1
Haberer, JP1
Politis, P1
Zakynthinos, E1
Kotanidou, A1
Andrianakis, I1
Roussos, C1
Kamibayashi, T1
Hayashi, Y1
Yamatodani, A1
Kawabata, K1
Yoshiya, I1
Canessa, R1
Lema, G1
Urzúa, J1
Dagnino, J1
Concha, M1
Dorrington, KL1
Glen, JB1
Hunter, SC1
Blackburn, TP1
Wood, P1
Galletly, DC1
Short, TG1
Harris, CE1
Murray, AM1
Anderson, JM1
Grounds, RM1
Morgan, M1
Ulsamer, B1
Doenicke, A1
Laschat, M1
Henriksson, BA1
Carlsson, P1
Hallén, B1
Hägerdal, M1
Lundberg, D1
Pontén, J1

Clinical Trials (12)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Comparative Study of Sevoflurane Sedation With TCI Propofol Sedation in Dialysis Dependent End Stage Renal Failure Patients for Transposition of Brachiocephalic Fistula Repair[NCT04839536]Phase 436 participants (Anticipated)Interventional2021-04-01Not yet recruiting
The Optimal Sequence in Same-day Bidirectional Endoscopy Under Deep Anesthesia Induced by Propofol Combined With Fentanyl: A Prospective Randomized Controlled ,Two Centers Trial[NCT04973878]544 participants (Anticipated)Interventional2021-07-30Not yet recruiting
Influence of Dexmedetomidine and Lidocaine on Opioid Consumption, Cognitive Function and Incidence of Neuropathic Pain in Laparoscopic Intestine Resection[NCT02616523]Phase 460 participants (Actual)Interventional2014-07-31Completed
Effects of Dexmedetomidine on Anaesthesia During IRE Procedures for Solid Tumours[NCT02044224]Phase 430 participants (Anticipated)Interventional2014-01-31Completed
Studio Clinico Pilota Con Uso di Elettroporazione Irreversibile (IRE) Nel Trattamento di Lesioni Neoplastiche Epatiche Con Localizzazione ad accessibilità Limitata o ad Alto Rischio[NCT01442324]5 participants (Anticipated)Interventional2011-02-28Recruiting
Randomized. Controlled Trial of the Utilization of High Flow Nasal Cannula for Oxygenation of Sedated Morbidly Obese Patients in the Endoscopy Suite[NCT02859597]41 participants (Actual)Interventional2016-12-28Completed
Evaluation of Mirus™ for Sedation in Resuscitation[NCT02889055]9 participants (Actual)Observational2016-01-17Terminated (stopped due to Safety profile was not satisfying with sevolflurane)
Goal Directed Propofol Sedation With Magnesium Sulphate Versus Dexmedetomidine for ERCP Procedure[NCT02684019]Phase 360 participants (Actual)Interventional2016-01-31Completed
An Observer Rating Scale of Facial Expression Can Predict Dreaming in Propofol Anesthesia[NCT04235894]124 participants (Actual)Observational2016-09-07Completed
[NCT02039453]160 participants (Anticipated)Interventional2013-09-30Recruiting
A Psychomotor Recuperation Study After Deep Sedation for Colonoscopy Between Target Controlled and Manual Titration of Propofol.[NCT02314559]Phase 4164 participants (Actual)Interventional2015-02-28Completed
Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture[NCT00188227]Phase 4748 participants Interventional2001-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Consumption of Fentanyl

consumption of fentanyl (mg) during the procedure (NCT02616523)
Timeframe: time of the operation

Interventionmg (Mean)
Dexmedetomidine41
Lidocaine50
Placebo58

Consumption of Piritramide

consumption of piritramide (mg) in the recovery room (NCT02616523)
Timeframe: one hour after the operation

Interventionmg (Mean)
Dexmedetomidine4.63
Lidocaine5.25
Placebo4.25

Neuropathic Pain (Pain Questionnaire) dn4

Pain questionnaire dn4 will be send to participants after two months of surgery to evaluate the neuropathic pain. There are minimum 0 points and maximum 10 points. If the score is 4 or higher then the pain is likely to be neuropathic pain. (NCT02616523)
Timeframe: two months after the surgery

Interventionunits on a scale (Mean)
Dexmedetomidine0.11
Lidocaine0.00
Placebo0.45

Ability to Maintain Oxygenation

The ease at which the Anesthesiologist is able to maintain adequate oxygenation during the period of sedation required for the procedure. the ability of each oxygen device to maintain oxygenation was based on the number of manipulations; more manipulations, the device is less effective at maintaining saturation for this population. (NCT02859597)
Timeframe: During the period of sedation, on average up to 1 hour

Interventionmanipulations (Mean)
High Flow Nasal Canula0.55
Nasal Canula0.61

Number of Participants Requiring Airway Adjuncts During Procedure

The use of airway adjuncts such as oral and nasal airways to insure adequate oxygenation during procedure. (NCT02859597)
Timeframe: During the period of sedation, on average up to 1 hour

InterventionParticipants (Count of Participants)
High Flow Nasal Cannula0
Nasal Cannula0

Number of Participants Who Need an Increase in Fraction of Inspired Oxygen

Need to increase the FiO2 to maintain adequate oxygenation (NCT02859597)
Timeframe: During period of sedation, on average up to 1 hour

InterventionParticipants (Count of Participants)
High Flow Nasal Canula6
Nasal Canula3

Reviews

10 reviews available for propofol and Arrhythmias, Cardiac

ArticleYear
Does dexmedetomidine have an antiarrhythmic effect on cardiac patients? A meta-analysis of randomized controlled trials.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Coronary Artery Bypass; Databases

2018
Propofol infusion syndrome: a structured review of experimental studies and 153 published case reports.
    Critical care (London, England), 2015, Nov-12, Volume: 19

    Topics: Anesthetics, Intravenous; Arrhythmias, Cardiac; Fever; Heart Failure; Hepatomegaly; Humans; Hypertri

2015
Similar Risk of Cardiopulmonary Adverse Events Between Propofol and Traditional Anesthesia for Gastrointestinal Endoscopy: A Systematic Review and Meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2017, Volume: 15, Issue:2

    Topics: Anesthesia; Anesthetics, Intravenous; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Humans; Hyp

2017
Propofol infusion syndrome: a rare complication with potentially fatal results.
    Critical care nurse, 2008, Volume: 28, Issue:3

    Topics: Acidosis; Acute Kidney Injury; Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Critical Care;

2008
[Propofol infusion syndrome].
    Annales francaises d'anesthesie et de reanimation, 2010, Volume: 29, Issue:5

    Topics: Acidosis; Arrhythmias, Cardiac; Heart Failure; Humans; Hypnotics and Sedatives; Infusions, Intraveno

2010
Propofol and arrhythmias: two sides of the coin.
    Acta pharmacologica Sinica, 2011, Volume: 32, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Gap Junctio

2011
The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Huma

2013
The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Huma

2013
The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Huma

2013
The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Huma

2013
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Propofol infusion syndrome: an overview of a perplexing disease.
    Drug safety, 2008, Volume: 31, Issue:4

    Topics: Acidosis; Anesthetics, Intravenous; Arrhythmias, Cardiac; Heart Failure; Hepatomegaly; Humans; Hypno

2008
Interaction studies and other investigations of the pharmacology of propofol ('Diprivan').
    Postgraduate medical journal, 1985, Volume: 61 Suppl 3

    Topics: Adrenergic beta-Antagonists; Anesthesia, Intravenous; Animals; Arrhythmias, Cardiac; Central Nervous

1985

Trials

15 trials available for propofol and Arrhythmias, Cardiac

ArticleYear
Sex-related differences in the effect-site concentration of remifentanil for preventing QTc interval prolongation following intubation in elderly patients with a normal QTc interval.
    Drugs & aging, 2014, Volume: 31, Issue:9

    Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Intravenous; Arrhythmias, Cardiac; Drug A

2014
Cardiac outcome after sevoflurane versus propofol sedation following coronary bypass surgery: a pilot study.
    Acta anaesthesiologica Scandinavica, 2011, Volume: 55, Issue:4

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Arrhythmias, Cardiac; Body Temperature; Conscious

2011
Differential effects of propofol and sevoflurane on QT interval during anesthetic induction.
    Journal of clinical monitoring and computing, 2013, Volume: 27, Issue:3

    Topics: Adult; Aged; Anesthetics; Arrhythmias, Cardiac; Arterial Pressure; Electrocardiography; Female; Hear

2013
QT interval and QT dispersion during the induction of anaesthesia in patients with subarachnoid haemorrhage: a comparison of thiopental and propofol.
    European journal of anaesthesiology, 2002, Volume: 19, Issue:10

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Arrhythmias, Cardiac; Electrocardiography; Female

2002
24-hour Holter-monitoring in the perianaesthetic period in dogs premedicated with dexmedetomidine.
    Veterinary journal (London, England : 1997), 2002, Volume: 164, Issue:3

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Arrhythmias, Cardia

2002
Supplemental remifentanil during coronary artery bypass grafting is followed by a transient postoperative cardiac depression.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:9

    Topics: Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Arrhythmias, Cardiac;

2004
Sedation for fiberoptic bronchoscopy: fewer adverse cardiovascular effects with propofol than with midazolam.
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2004, Volume: 39, Issue:10

    Topics: Anesthetics, Intravenous; Arrhythmias, Cardiac; Bronchoscopy; Cardiovascular Diseases; Cardiovascula

2004
Incidence of post-anaesthetic arrhythmias in dogs.
    The Journal of small animal practice, 2005, Volume: 46, Issue:3

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Dog Diseases; Dogs

2005
Adding remifentanil to propofol and etomidate in cardioversion anesthesia.
    Saudi medical journal, 2007, Volume: 28, Issue:10

    Topics: Aged; Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Arrhythmias, Cardiac; Electric Count

2007
Effect of esmolol on the hemodynamic and electrocardiographic changes during laryngomicroscopy under propofol-alfentanil anesthesia.
    Acta anaesthesiologica Belgica, 1998, Volume: 49, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Alfentanil; Analysis of Variance; Anesthesia, Intravenous;

1998
Influence of anaesthesia on defibrillation threshold.
    Anaesthesia, 1998, Volume: 53, Issue:12

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Arrhythmias, Cardiac; Defibr

1998
Induction characteristics of thiopentone/suxamethonium, propofol/alfentanil or halothane alone in children aged 1-3 years.
    European journal of anaesthesiology, 1999, Volume: 16, Issue:6

    Topics: Adenoidectomy; Alfentanil; Ambulatory Surgical Procedures; Anesthesia; Anesthetics, Combined; Anesth

1999
Anesthesia for elective cardioversion: a comparison of four anesthetic agents.
    Journal of cardiothoracic and vascular anesthesia, 1991, Volume: 5, Issue:6

    Topics: Adult; Aged; Anesthesia, Intravenous; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Ele

1991
[Propofol in comparison with etomidate for the induction of anesthesia].
    Der Anaesthesist, 1986, Volume: 35, Issue:9

    Topics: Adult; Aged; Anesthetics; Arrhythmias, Cardiac; Etomidate; Female; Hemodynamics; Humans; Male; Middl

1986
Propofol vs thiopentone as anaesthetic agents for short operative procedures.
    Acta anaesthesiologica Scandinavica, 1987, Volume: 31, Issue:1

    Topics: Anesthesia, Intravenous; Anesthetics; Arrhythmias, Cardiac; Dilatation and Curettage; Female; Hemody

1987

Other Studies

54 other studies available for propofol and Arrhythmias, Cardiac

ArticleYear
Modeling propofol-induced cardiotoxicity in the isolated-perfused newborn mouse heart.
    Physiological reports, 2022, Volume: 10, Issue:15

    Topics: Animals; Animals, Newborn; Arrhythmias, Cardiac; Cardiotoxicity; Heart; Humans; Mice; Myocytes, Card

2022
The effect of propofol on frontal QRS-T angle in patients undergoing elective colonoscopy procedure.
    Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:1

    Topics: Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Colonoscopy; Cross-Sectional Studies; Electro

2020
Reply to letter "A fatal adverse event upon adenotonsillectomy in a child. Are Brugada syndrome and propofol real accomplices?"
    Cardiology in the young, 2020, Volume: 30, Issue:9

    Topics: Arrhythmias, Cardiac; Brugada Syndrome; Child; Humans; Propofol; Ventricular Fibrillation

2020
Sevoflurane in patients at risk of ventricular dysrhythmias.
    Journal of anesthesia, 2017, Volume: 31, Issue:5

    Topics: Anesthetics, Intravenous; Arrhythmias, Cardiac; Humans; Methyl Ethers; Propofol; Sevoflurane

2017
Propofol: a safe anaesthetic drug in experimental cardiac surgery in rabbits.
    Annali italiani di chirurgia, 2018, Volume: 89

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Ar

2018
Procedural sedation by advanced care paramedics for emergency gastrointestinal endoscopy.
    CJEM, 2019, Volume: 21, Issue:2

    Topics: Allied Health Personnel; Analgesics; Arrhythmias, Cardiac; Datasets as Topic; Emergency Service, Hos

2019
Propofol Induced Hyperkalemia and Its Management in End Stage Renal Disease Patients.
    Connecticut medicine, 2016, Volume: 80, Issue:8

    Topics: Anesthetics, Intravenous; Arrhythmias, Cardiac; Electrocardiography; Heart Arrest; Humans; Hyperkale

2016
Propofol infusion-like syndrome in a dog.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2018, Volume: 59, Issue:11

    Topics: Acidosis; Acute Kidney Injury; Animals; Arrhythmias, Cardiac; Dog Diseases; Dogs; Female; Hypnotics

2018
Propofol-related infusion syndrome: role of propofol in medical complications of sedated critical care patients.
    The Permanente journal, 2013,Spring, Volume: 17, Issue:2

    Topics: Arrhythmias, Cardiac; Fatal Outcome; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male;

2013
Propofol infusion syndrome: a lethal condition in critically injured patients eliminated by a simple screening protocol.
    Injury, 2014, Volume: 45, Issue:1

    Topics: Acidosis; Acute Kidney Injury; Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Cohort Studies

2014
Propofol-related infusion syndrome heralding a mitochondrial disease: case report.
    Neurology, 2013, Aug-20, Volume: 81, Issue:8

    Topics: Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Diagnosis, Differential; Fatal Outcome; Femal

2013
Procedural sedation with propofol for emergency DC cardioversion.
    Emergency medicine journal : EMJ, 2014, Volume: 31, Issue:11

    Topics: Aged; Aged, 80 and over; Arrhythmias, Cardiac; Conscious Sedation; Electric Countershock; Emergency

2014
Safe single-dose administration of propofol in patients with established Brugada syndrome: a retrospective database analysis.
    Pacing and clinical electrophysiology : PACE, 2013, Volume: 36, Issue:12

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Brugada Syndrome; Child; Databases, Factual; Dose-Res

2013
Management and complications of anaesthesia during balloon valvuloplasty for pulmonic stenosis in dogs: 39 cases (2000 to 2012).
    The Journal of small animal practice, 2014, Volume: 55, Issue:4

    Topics: Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Arrhythmias, Card

2014
Propofol-related infusion syndrome heralding a mitochondrial disease: case report.
    Neurology, 2014, Feb-04, Volume: 82, Issue:5

    Topics: Arrhythmias, Cardiac; Female; Humans; Mitochondrial Diseases; Propofol; Renal Insufficiency; Rhabdom

2014
Author response.
    Neurology, 2014, Feb-04, Volume: 82, Issue:5

    Topics: Arrhythmias, Cardiac; Female; Humans; Mitochondrial Diseases; Propofol; Renal Insufficiency; Rhabdom

2014
Cardiac Dysrhythmias in Children Undergoing Extracorporeal Shock Wave Lithotripsy Under General Anesthesia or Propofol Sedation: A Prospective, Observational Cohort Study.
    Urology, 2015, Volume: 86, Issue:5

    Topics: Adolescent; Anesthesia, General; Arrhythmias, Cardiac; Child; Child, Preschool; Cohort Studies; Elec

2015
Differential effects of propofol and sevoflurane on ischemia-induced ventricular arrhythmias and phosphorylated connexin 43 protein in rats.
    Anesthesiology, 2009, Volume: 110, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Connexin 43; Heart Rate; Male; Methyl Ethers; Myocardial Ischemia; Ph

2009
Appendectomy for an adult with cyanotic congenital heart disease.
    Minerva anestesiologica, 2009, Volume: 75, Issue:4

    Topics: Androstanols; Anesthesia, Intravenous; Appendectomy; Appendicitis; Arrhythmias, Cardiac; Contraindic

2009
Heart rate variability during total intravenous anesthesia: effects of nociception and analgesia.
    Autonomic neuroscience : basic & clinical, 2009, May-11, Volume: 147, Issue:1-2

    Topics: Adult; Afferent Pathways; Anesthetics; Anesthetics, Intravenous; Arrhythmias, Cardiac; Consciousness

2009
Propofol and cardioprotection against arrhythmias.
    Anesthesiology, 2009, Volume: 111, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Biomarkers; Cardiotonic Agents; Connexin 43

2009
Propofol infusion syndrome with arrhythmia, myocardial fat accumulation and cardiac failure.
    The American journal of cardiology, 2009, Oct-15, Volume: 104, Issue:8

    Topics: Arrhythmias, Cardiac; Brain Edema; Brain Injuries; Child; Diagnosis, Differential; Fatal Outcome; He

2009
Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter study.
    Critical care (London, England), 2009, Volume: 13, Issue:5

    Topics: Academic Medical Centers; Adult; Aged; Anesthetics, Intravenous; Arrhythmias, Cardiac; Critical Illn

2009
Irreversible electroporation: a new challenge in "out of operating theater" anesthesia.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; A

2010
Irreversible electroporation: a new challenge in "out of operating theater" anesthesia.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; A

2010
Irreversible electroporation: a new challenge in "out of operating theater" anesthesia.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; A

2010
Irreversible electroporation: a new challenge in "out of operating theater" anesthesia.
    Anesthesia and analgesia, 2010, May-01, Volume: 110, Issue:5

    Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; A

2010
Anesthesia induction with sevoflurane and propofol: evaluation of P-wave dispersion, QT and corrected QT intervals.
    The Kaohsiung journal of medical sciences, 2010, Volume: 26, Issue:9

    Topics: Adolescent; Adult; Anesthetics; Arrhythmias, Cardiac; Cardiovascular Physiological Phenomena; Drug E

2010
Reversible lactic acidosis and electrocardiographic changes in a neurosurgical patient during propofol anesthesia.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:5

    Topics: Acidosis, Lactic; Anesthetics, Inhalation; Anesthetics, Intravenous; Arrhythmias, Cardiac; Electroca

2010
A prospective assessment of sedation-related adverse events and patient and endoscopist satisfaction in ERCP with anesthesiologist-administered sedation.
    Gastrointestinal endoscopy, 2011, Volume: 73, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthetics, Intravenous; Ar

2011
Propofol infusion syndrome--a critical incident report highlighting the danger of reexposure.
    Journal of neurosurgical anesthesiology, 2011, Volume: 23, Issue:3

    Topics: Adult; Arrhythmias, Cardiac; Head Injuries, Closed; Humans; Hypnotics and Sedatives; Hypotension; In

2011
Propofol decreases reperfusion-induced arrhythmias in a model of "border zone" between normal and ischemic-reperfused guinea pig myocardium.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:5

    Topics: Action Potentials; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Electrodes, Implanted; E

2003
[Comparison of the influence of different anesthetic protocols in the development of post-anesthetic arrhythmia in the dog].
    DTW. Deutsche tierarztliche Wochenschrift, 2003, Volume: 110, Issue:10

    Topics: Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Diazepam; Dog Diseases; Dogs; Electrocardio

2003
Effects of propafenone associated with propofol on myocardial contractility, heart rate, coronary flow, and the incidence of arrhythmia in isolated hearts of rats.
    Arquivos brasileiros de cardiologia, 2004, Volume: 82, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulatio

2004
A case of propofol toxicity: further evidence for a causal mechanism.
    Paediatric anaesthesia, 2004, Volume: 14, Issue:6

    Topics: Acidosis; Acute Kidney Injury; Arrhythmias, Cardiac; Cleft Lip; Conscious Sedation; Humans; Hypnotic

2004
Comparative effects of thiopental and propofol on atrial vulnerability: electrophysiological study in a porcine model including acute alcoholic intoxication.
    British journal of anaesthesia, 2004, Volume: 93, Issue:3

    Topics: Alcoholic Intoxication; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Atrial Flutter; Atr

2004
[Propofol infusion syndrome in children].
    Ugeskrift for laeger, 2005, Sep-26, Volume: 167, Issue:39

    Topics: Acidosis, Lactic; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Child; Hepatomegaly; Huma

2005
Propofol infusion syndrome during anaesthesia for scoliosis surgery in an adolescent with neonatal progeroid syndrome.
    Acta anaesthesiologica Scandinavica, 2006, Volume: 50, Issue:3

    Topics: Acidosis; Adolescent; Anesthetics, Intravenous; Arrhythmias, Cardiac; Female; Humans; Progeria; Prop

2006
[Propofol infusion syndrome].
    Der Anaesthesist, 2006, Volume: 55, Issue:11

    Topics: Acidosis; Acute Kidney Injury; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Arrhythmias,

2006
Prevalence of perioperative arrhythmias in 50 young, healthy dogs.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2007, Volume: 48, Issue:2

    Topics: Animals; Animals, Newborn; Arrhythmias, Cardiac; Dog Diseases; Dogs; Electrocardiography, Ambulatory

2007
Cardiac arrhythmias following anesthesia induction in infantile-onset Pompe disease: a case series.
    Paediatric anaesthesia, 2007, Volume: 17, Issue:8

    Topics: alpha-Glucosidases; Anesthesia, General; Anesthetics, Intravenous; Arrhythmias, Cardiac; Clinical Tr

2007
The influence of propofol versus sevoflurane anesthesia on outcome in 10,535 cardiac surgical procedures.
    Journal of cardiothoracic and vascular anesthesia, 2007, Volume: 21, Issue:5

    Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Arrhythmias, Cardiac;

2007
[Use of Diprivan in cardioversion and interventional cardiology].
    Annales francaises d'anesthesie et de reanimation, 1994, Volume: 13, Issue:4

    Topics: Anesthesia, Intravenous; Arrhythmias, Cardiac; Electric Countershock; Humans; Propofol

1994
A comparison of propofol and methohexitone for dental chair anaesthesia in children.
    Anaesthesia, 1993, Volume: 48, Issue:3

    Topics: Adolescent; Anesthesia, Dental; Arrhythmias, Cardiac; Blood Pressure; Child; Child, Preschool; Femal

1993
Fatal outcome after propofol sedation in children.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:5

    Topics: Acidosis; Arrhythmias, Cardiac; Cardiac Output, Low; Cause of Death; Child; Creatine Kinase; Dantrol

1997
Propofol and malignant hyperthermia susceptibility.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:5

    Topics: Acidosis; Adolescent; Adult; Aged; Anesthetics, Intravenous; Arrhythmias, Cardiac; Cause of Death; C

1997
A comparison of the effects of propofol and sevoflurane on the systemic toxicity of intravenous bupivacaine in rats.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:1

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Anesthetics, Local; Animals; Arrhythmias, Cardiac

1999
Total intravenous anesthesia with remifentanil and propofol for implantation of cardioverter-defibrillators in patients with severely reduced left ventricular function.
    Journal of cardiothoracic and vascular anesthesia, 1999, Volume: 13, Issue:1

    Topics: Aged; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Arrhythmias, Cardiac

1999
[Anesthetic management for implantation of implantable cardioverter-defibrillators].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48, Issue:7

    Topics: Adult; Aged; Anesthesia, General; Anesthesia, Local; Arrhythmias, Cardiac; Defibrillators, Implantab

1999
Multiple agents potentiate alpha1-adrenoceptor-induced conduction depression in canine cardiac purkinje fibers.
    Anesthesiology, 2000, Volume: 92, Issue:6

    Topics: Action Potentials; Adrenergic alpha-Agonists; Anesthetics; Animals; Arrhythmias, Cardiac; Dogs; Drug

2000
Death related to propofol use in an adult patient.
    Critical care medicine, 2000, Volume: 28, Issue:8

    Topics: Acidosis; Adolescent; Arrhythmias, Cardiac; Fatal Outcome; Heart Failure; Humans; Male; Propofol; Re

2000
[Premedication and sedation complications during ophthalmic anesthesia].
    Journal francais d'ophtalmologie, 2000, Volume: 23, Issue:9

    Topics: Adjuvants, Anesthesia; Alfentanil; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anesthesi

2000
Propofol use in head-injury patients.
    Lancet (London, England), 2001, May-26, Volume: 357, Issue:9269

    Topics: Adolescent; Adult; Age Factors; Anesthetics, Intravenous; Arrhythmias, Cardiac; Cause of Death; Cere

2001
Enhancement by propofol of epinephrine-induced arrhythmias in dogs.
    Anesthesiology, 1991, Volume: 75, Issue:6

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Dogs; Dose-Response Relationship, Drug; Drug Synergism; E

1991
Asystole with convulsion following a subanesthetic dose of propofol plus fentanyl.
    Anaesthesia, 1989, Volume: 44, Issue:8

    Topics: Adult; Anesthesia, Intravenous; Arrhythmias, Cardiac; Drug Combinations; Fentanyl; Heart Arrest; Hum

1989
Total intravenous anaesthesia using propofol infusion--50 consecutive cases.
    Anaesthesia and intensive care, 1988, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Anesthetics; Arrhythmias, Cardi

1988
Effects of thiopentone, etomidate and propofol on the haemodynamic response to tracheal intubation.
    Anaesthesia, 1988, Volume: 43 Suppl

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Anesthetics; Arrhythmias, Cardiac; Etomidate; Female; He

1988