propofol has been researched along with Apnea in 112 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Apnea: A transient absence of spontaneous respiration.
Excerpt | Relevance | Reference |
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"To evaluate the effect of rate of administration of propofol or alfaxalone on induction dose requirements and incidence of postinduction apnea (PIA) in dogs following premedication with methadone and dexmedetomidine." | 9.24 | Effect of rate of administration of propofol or alfaxalone on induction dose requirements and occurrence of apnea in dogs. ( Bauquier, S; Beths, T; Bigby, SE; Carter, JE, 2017) |
"Capnography provides noninvasive monitoring of ventilation and can enable early recognition of altered respiration patterns and apnea." | 9.17 | Capnography improves detection of apnea during procedural sedation for percutaneous transhepatic cholangiodrainage. ( Kochs, EF; Schlag, C; Schmid, RM; von Delius, S; Wagenpfeil, S; Wörner, A, 2013) |
"Although the largest decrease in propofol dosage required for intubation was after IV premedication with acepromazine and butorphanol, hypotension and apnea still occurred." | 8.12 | Effects of intravenous acepromazine and butorphanol on propofol dosage for induction of anesthesia in healthy Beagle dogs. ( Dantino, SC; Kleine, SA; Seddighi, R; Smith, CK; Smith, SM; Zhu, X, 2022) |
" In young children, sedation is likely to be needed, and multiple controlled periods of apnea are often required to allow image acquisition." | 8.02 | Study to evaluate the optimal dose of remifentanil required to ensure apnea during magnetic resonance imaging of the heart under general anesthesia. ( Arnold, P; Cowen, R; Davis, A; Hampson, LV; Jaki, T; Kaleem, M; Sanaulla, S; Tan, J; Wadsworth, I; Williams, A, 2021) |
" Induction of apnea and positive pressure ventilation are required for accurate PFT measurements in non-cooperative subjects." | 7.88 | Apnea induction for invasive lung function testing in infant olive baboons: Comparison of intravenous propofol versus hyperventilation. ( Anderson, MP; Hill, CL; Ivanov, VA; Papin, JF; Welliver, RC; Wolf, RF, 2018) |
" To clarify these relationships in different airway devices would be useful to avoid the complication such as apnea and intraoperative awareness." | 7.88 | Comparison of plasma propofol concentration for apnea, response to mechanical ventilation, and airway device between endotracheal tube and supraglottic airway device in Beagles. ( Iizuka, T; Kanazawa, H; Masui, K; Nishimura, R, 2018) |
"The objective of this study was to characterize the propofol-fentanyl interaction in Beagles for four pharmacodynamic endpoints: apnea, response to mechanical ventilation, endotracheal tube, and tetanic stimulation." | 7.85 | Propofol-fentanyl interaction in Beagles - Apnea, response to mechanical ventilation, endotracheal tube, and tetanic stimulation. ( Iizuka, T; Kanazawa, H; Masui, K; Miyabe-Nishiwaki, T; Nishimura, R, 2017) |
"We describe the characteristics of and predictors for apnea and clinical interventions during emergency department (ED) procedural sedation." | 7.83 | Characteristics of and Predictors for Apnea and Clinical Interventions During Procedural Sedation. ( Andolfatto, G; Krauss, BA; Krauss, BS; Mieloszyk, RJ; Monuteaux, MC, 2016) |
" We present a case of a 35-year-old suicidal man who developed prolonged apnea for almost 4 hours on day 13 of OP poisoning after brief general anesthesia induced by propofol and 1 mg/kg of suxamethonium, during the first session of the third cycle of modified electroconvulsive therapy, despite all due precautions." | 7.83 | Prolonged Apnea During Modified Electroconvulsive Therapy in a Patient of Suicidal Attempt by Organophosphorus Poisoning: A Case Report. ( Dhakne, R; Khairkar, P; Kumar, V; Mishra, KK, 2016) |
"Undetected apnea can lead to severe hypoxia, bradycardia, and cardiac arrest." | 7.79 | Using the entropy of tracheal sounds to detect apnea during sedation in healthy nonobese volunteers. ( Brewer, LM; Egan, TD; Hill, BE; Johnson, KB; Orr, JA; Ting, CK; Westenskow, DR; Yu, L, 2013) |
" Propofol's disadvantages include the induction of respiratory depression and apnea." | 7.79 | Coadministration of the AMPAKINE CX717 with propofol reduces respiratory depression and fatal apneas. ( Ding, X; Greer, JJ; Lenal, F; Ren, J; Yang, M, 2013) |
" It appeared that succinylcholine-induced apnea was responsible for the prolonged apnea." | 7.78 | Hemoglobin desaturation after propofol/remifentanil-induced apnea: a study of the recovery of spontaneous ventilation in healthy volunteers. ( Brown, R; Caldwell, JE; Feiner, J; Krombach, J; Stefanutto, TB, 2012) |
"We present a patient with myotonic dystrophy (MD) who was anesthetized with propofol using a target-controlled technique for electrophysiologic examination and cardiac catheter ablation." | 7.73 | Target-controlled infusion of propofol for a patient with myotonic dystrophy. ( Hirata, T; Matayoshi, H; Mii, M; Morimoto, Y; Sakabe, T, 2005) |
" Seven of the 21 patients with Rett syndrome compared with none of the control patients experienced a serious adverse event, most of which were due to prolonged apnea (P = ." | 7.73 | Deep sedation with propofol in patients with Rett syndrome. ( Buckmaster, MA; Callans, BH; Islam, MP; Percy, AK; Tofil, NM; Winkler, MK, 2006) |
"Apnea was determined to be the serious adverse effect for all dogs." | 7.70 | Respiratory depression and apnea induced by propofol in dogs. ( Gadawski, JE; Muir, WW, 1998) |
"Assessment of pain on injection of the emulsified formulation of di-isopropylphenol (propofol, 'Diprivan') was undertaken in 120 unpremedicated patients and comparison made with thiopentone." | 7.67 | Assessment and modification of pain on induction with propofol (Diprivan). ( Lees, NW; McCulloch, MJ, 1985) |
"Overall, propofol induced a significant incidence of relative hypotension (mean arterial pressure 20% below baseline, 45%), apnoea (71%) and haemoglobin desaturation (65%) at induction of anaesthesia, with a higher incidence of hypotension and apnoea in the P-CRI than P-TCI group (68% versus 21%, p = 0." | 5.69 | Comparison between continuous rate infusion and target-controlled infusion of propofol in dogs: a randomized clinical trial. ( Cuniberti, B; Hughes, JL; Huuskonen, V, 2023) |
"The effectiveness and side effects of dexmedetomidine (DEX) in combination with midazolam and propofol have not been comparatively studied in a single clinical trial as sedative agents to general anesthesia before." | 5.51 | Comparison of Intra and Post-operative Sedation Efficacy of Dexmedetomidinemidazolam and Dexmedetomidine-propofol for Major Abdominal Surgery. ( Gao, Y; Yan, F, 2022) |
" Complications including apnea, hypotension, hypoxia, nausea, and vomiting, along with gastroenterologist satisfaction and patients' pain score (based on Wong-Baker faces pain assessment scale), were recorded by a checklist." | 5.51 | Comparing the Efficacy and Safety of Dexmedetomidine/Ketamine with Propofol/Fentanyl for Sedation in Colonoscopy Patients: A Doubleblinded Randomized Clinical Trial. ( Aghaali, M; Ahmadpour, S; Alemi, F; Aminnejad, R; Hormati, A; Hormati, M; Sabouri, SM; Saeidi, M; Shafiee, H, 2022) |
"To evaluate the effect of rate of administration of propofol or alfaxalone on induction dose requirements and incidence of postinduction apnea (PIA) in dogs following premedication with methadone and dexmedetomidine." | 5.24 | Effect of rate of administration of propofol or alfaxalone on induction dose requirements and occurrence of apnea in dogs. ( Bauquier, S; Beths, T; Bigby, SE; Carter, JE, 2017) |
" The apnea time was not significantly different between the two groups." | 5.24 | The effect of dexmedetomidine pretreatment on the median effective bolus dose of propofol for facilitating laryngeal mask airway insertion. ( Kim, JY; Kim, YB; Kwak, HJ; Lee, SY; Park, CK; Yoo, JY, 2017) |
" However, IPI registration was more effective in reducing the incidence of apnea episodes." | 5.24 | Clinical value of the Integrated Pulmonary Index ( Beitz, A; Geist, C; Heringlake, S; Kronshage, T; Meining, A; Müller, M; Pox, CP; Riphaus, A; Schmiegel, W; von Delius, S; Wehrmann, T, 2017) |
" The primary outcome was the occurrence of a respiratory adverse event (desaturation, apnea, or hypoventilation) requiring an intervention by the sedating physician." | 5.22 | Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial. ( Bell, A; Ding, M; Ferguson, I; Holdgate, A; New, L; Treston, G, 2016) |
" Patients in the left lateral arm showed lower apnea rates (9." | 5.20 | Patient position and hypoxemia during propofol sedation for colonoscopy: a randomized trial. ( Haller, B; Huth, M; Huth, R; Klare, P; Reindl, W; Schlag, C; Schmid, RM; von Delius, S; Weber, A, 2015) |
"Capnography enables the measurement of end-tidal CO2 and thereby the early detection of apnea, prompting immediate intervention to restore ventilation." | 5.19 | Capnographic monitoring of propofol-based sedation during colonoscopy. ( Albert, J; Bojunga, J; Filmann, N; Friedrich-Rust, M; Herrmann, E; Kannengiesser, M; Meckbach, Y; Schroeter, H; Trojan, J; Welte, C; Welte, M; Zeuzem, S, 2014) |
"Capnography provides noninvasive monitoring of ventilation and can enable early recognition of altered respiration patterns and apnea." | 5.17 | Capnography improves detection of apnea during procedural sedation for percutaneous transhepatic cholangiodrainage. ( Kochs, EF; Schlag, C; Schmid, RM; von Delius, S; Wagenpfeil, S; Wörner, A, 2013) |
"022) were significantly lower, and apnea duration (P < 0." | 5.17 | Comparison of effects of propofol and ketamine-propofol mixture (ketofol) on laryngeal mask airway insertion conditions and hemodynamics in elderly patients: a randomized, prospective, double-blind trial. ( Aydogan, MS; Begec, Z; Colak, C; Durmus, M; Erdogan, MA; Ozgul, U; Yucel, A, 2013) |
" The incidence of apnea was greater in Group 3P patients (17/30, 57%) than in Group 2P (2/30, 7%) or Group 2PL patients (1/30, 3%) (P < 0." | 5.14 | Topical lidocaine improves conditions for laryngeal mask airway insertion. ( Changchien, CF; Chen, HS; Hsieh, SW; Hung, KC; Lin, VC; Liu, CC; Liu, PH; Tan, PH, 2010) |
" Episodes of apnea or hypoventilation detected by capnography were compared with the occurrence of hypoxemia." | 5.14 | Capnography is superior to pulse oximetry for the detection of respiratory depression during colonoscopy. ( Barbado, A; Cacho, G; Fernández-Rodríguez, CM; Lledó, JL; Ojea, R; Pérez-Calle, JL, 2010) |
"The model adequately described the data including the occurrence of apnea." | 5.14 | Modeling the non-steady state respiratory effects of remifentanil in awake and propofol-sedated healthy volunteers. ( Aarts, L; Boom, M; Dahan, A; Nieuwenhuijs, D; Olofsen, E; Sarton, E; Teppema, L, 2010) |
" Apnea periods >20 seconds and decreases in SaO2 <90% occurred more frequently in group R (31." | 5.14 | Remifentanil versus fentanyl for esophagogastroduodenoscopy in children. ( Hirsh, I; Lerner, A; Pacht, A; Pizov, R; Reuveni, A; Segol, O; Shnaider, I, 2010) |
"During sevoflurane/nitrous oxide anesthesia, propofol 3 mg x kg(-1) provides superior intubating conditions with an increased incidence of and prolonged apnea compared with 0 and 0." | 5.14 | Propofol for tracheal intubation in children anesthetized with sevoflurane: a dose-response study. ( Burrows, FA; Houck, J; Houle, TT; Lerman, J; Matthews, BT, 2009) |
" The duration of apnea showed a significant dose-related increase (P < 0." | 5.14 | The use of remifentanil to facilitate the insertion of the Cobra perilaryngeal airway. ( Cho, SY; Jeon, WJ; Kim, KH; Suh, JK, 2009) |
" Frequency of apnea was significantly higher in the remifentanil group (P < 0." | 5.13 | Intravenous remifentanil and propofol for gastroscopy. ( Liu, J; Si, YY; Wang, X; Wu, JC; Xu, ZY; Xue, FS; Zuo, YX, 2008) |
" During CV, time to reach Ramsay Sedation Scale level 5 (RSS-5; induction time); time to reach RSS-2 (recovery time); and side effects including desaturation, apnea, and changes in hemodynamic parameters were recorded by a person blinded to the patient treatment allocation." | 5.12 | Age effect on efficacy and side effects of two sedation and analgesia protocols on patients going through cardioversion: a randomized clinical trial. ( Erdur, B; Ergin, A; Parlak, I; Parlak, M; Sagiroglu, E, 2006) |
" The duration of apnea was recorded." | 5.12 | Alfentanil dosage when inserting the classic laryngeal mask airway. ( Critchley, LA; Gin, T; Lee, A; Yu, AL, 2006) |
" The authors hypothesized that the incidence of apnea with laryngospasm evoked by laryngeal stimulation would not differ between sevoflurane and propofol when used in equipotent doses and that laryngeal responsiveness would be diminished with increased levels of hypnosis." | 5.11 | Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients. ( Erb, TO; Frei, FJ; Oberer, C; von Ungern-Sternberg, BS, 2005) |
" While oxygen desaturation and apnea were not observed in any of the patients in group PK, there were four patients (11." | 5.11 | Comparison of propofol with propofol-ketamine combination in pediatric patients undergoing auditory brainstem response testing. ( Akin, A; Aydogan, H; Boyaci, A; Esmaoglu, A; Gulcu, N; Tosun, Z, 2005) |
"05), as well as a more frequent incidence of apnea (84% in the propofol group versus 7% and 16% in the sevoflurane and sevoflurane-propofol groups, respectively; P < 0." | 5.11 | A comparison of sevoflurane-propofol versus sevoflurane or propofol for laryngeal mask airway insertion in adults. ( Aouad, MT; Baraka, AS; Daaboul, DG; Deeb, PG; Massouh, FM; Muallem, MA; Siddik-Sayyid, SM; Taha, SK, 2005) |
"4%), including hypotension in 5, hypoxemia in 7, and apnea in 5." | 5.11 | Propofol for deep procedural sedation in the ED. ( Baire, M; Frazee, BW; Lowery, D; Park, RS, 2005) |
" Transient apnea was noted in 20% of patients receiving propofol." | 5.10 | Propofol compared with general anesthesia for pediatric GI endoscopy: is propofol better? ( Bhattacharya, D; Kaddu, R; Metriyakool, K; Thomas, R; Tolia, V, 2002) |
" The necessary use of additional dosage of propofol and the duration of post-induction apnea were also recorded." | 5.09 | Comparison between two different propofol dosage regimens for insertion of cuffed oro-pharyngeal airway. ( Charissi, N; Dimitriou, V; Kostantopoulou, G; Voyagis, GS, 1999) |
"To compare the respiratory depressant effects of propofol and sevoflurane used to facilitate the placement of the cuffed oropharyngeal airway (COPA), and to evaluate the effectiveness of the COPA in supporting positive pressure ventilation during anesthetic-induced apnea." | 5.09 | Insertion of the cuffed oropharyngeal airway (COPA) with propofol or sevoflurane in adults. ( Goto, T; Morita, S; Nakata, Y; Niimi, Y; Uchiyama, M; Uezono, S, 1999) |
" Apnea occurred in 11 patients (7." | 5.08 | A multicenter evaluation of remifentanil for early postoperative analgesia. ( Bowdle, TA; Camporesi, EM; Hogue, CW; Maysick, L; Miguel, RV; Pitts, M; Streisand, JB, 1996) |
"To determine the median effective dose (ED50) of propofol required for induction of anesthesia in goats and the frequency of myoclonic activity and apnea associated with propofol administration." | 5.08 | Median effective dose of propofol required for induction of anaesthesia in goats. ( Bailey, JE; Ko, JC; Pablo, LS, 1997) |
" Cardiac morbidity (postoperative myocardial ischemia, postoperative myocardial infarction, and perioperative sympathoadrenal stress response), respiratory morbidity (postextubation apnea, alveolar-arterial oxygen gradient, pulmonary shunting, oxygen consumption, atelectasis, and reintubation), hemodynamic values and vasoactive medication requirements, intraoperative awareness, postoperative cognitive function, 30 day mortality, and intensive care unit and hospital lengths of stay were compared between the two groups." | 5.08 | Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial. ( Asokumar, B; Carroll, J; Cheng, DC; David, T; Karski, J; Mickle, D; Nierenberg, H; Peniston, C; Raveendran, G; Roger, S; Sandler, A; Tong, J; Zelovitsky, J, 1996) |
" Ketamine had no influence on the incidence of apnea after propofol, and the net hemodynamic effects were minimal." | 5.08 | Additive interactions between propofol and ketamine when used for anesthesia induction in female patients. ( Gin, T; Hong, W; Hui, TW; Plummer, J; Short, TG; Suen, T, 1995) |
" The effects of propofol on cecal intubation rates, and occurrences of hypotension and apnea were similar to those of TAs." | 5.05 | Safety and efficacy of propofol alone or in combination with other agents for sedation of patients undergoing colonoscopy: an updated meta-analysis. ( Li, HT; Xu, H; Zhang, K, 2020) |
" Providers of all sedation types should be aware of hypotension, apnea, hypoventilation, and hypoxia that can develop and they should be able to manage the patient under these circumstances." | 5.01 | Moderate and deep sedation training and pharmacology for nonanesthesiologists: recommendations for effective practice. ( Beutler, SS; Tran, TT; Urman, RD, 2019) |
"17), and the reduction in apnea or hyoxemia (OR=0." | 4.95 | The Comparison of Etomidate and Propofol Anesthesia in Patients Undergoing Gastrointestinal Endoscopy: A Systematic Review and Meta-Analysis. ( Xiao, X; Ye, L; Zhu, L, 2017) |
", hypoxia, hypotension, arrhythmia, and apnea) and sedation profiles were assessed." | 4.89 | The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis. ( Chen, C; Chen, J; Deng, D; Liu, J; Long, A; Tang, D; Wang, D; Wang, L; Xu, Y; Zhu, Z, 2013) |
" The following 4 cardiopulmonary complications were assessed: hypoxia, hypotension, arrhythmias, and apnea." | 4.82 | Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis. ( Khandwala, F; Lopez, R; Qadeer, MA; Vargo, JJ; Zuccaro, G, 2005) |
" Two of 5 rhinoceros experienced apnea after propofol administration." | 4.31 | Pharmacokinetics of intravenous propofol in southern white rhinoceros (Ceratotherium simum simum) after intramuscular etorphine-butorphanol-medetomidine-azaperone. ( Berlin, ER; Clancy, MM; Ferris, RL; Howard, LL; Kinney, ME; Knych, HK; Mama, KR; Perrin, KL; Phair, KA, 2023) |
" We compare AIAE rates (coughing, gagging, apnea, airway obstruction, and laryngospasm) in children who received TPA as part of their propofol-based procedural sedation for EGD with those who did not receive TPA." | 4.31 | Topical Pharyngeal Anesthesia in Sedated Pediatric Patients Undergoing Esophagogastroduodenoscopy. ( Aljabari, S; El-Halabi, I; Friedman, S; Ohler, A; Tryon, C; Waheed, S, 2023) |
"Although the largest decrease in propofol dosage required for intubation was after IV premedication with acepromazine and butorphanol, hypotension and apnea still occurred." | 4.12 | Effects of intravenous acepromazine and butorphanol on propofol dosage for induction of anesthesia in healthy Beagle dogs. ( Dantino, SC; Kleine, SA; Seddighi, R; Smith, CK; Smith, SM; Zhu, X, 2022) |
" Both treatments produced a rapid loss of consciousness, no apnea, and physiological parameters were maintained within clinically acceptable ranges apart from transient hypoxemia." | 4.02 | Comparison of the anesthetic effects between 5 mg/kg of alfaxalone and 10 mg/kg of propofol administered intravenously in cats. ( Fukui, S; Oyama, N; Tamura, J; Yamashita, K, 2021) |
" In young children, sedation is likely to be needed, and multiple controlled periods of apnea are often required to allow image acquisition." | 4.02 | Study to evaluate the optimal dose of remifentanil required to ensure apnea during magnetic resonance imaging of the heart under general anesthesia. ( Arnold, P; Cowen, R; Davis, A; Hampson, LV; Jaki, T; Kaleem, M; Sanaulla, S; Tan, J; Wadsworth, I; Williams, A, 2021) |
" Induction of apnea and positive pressure ventilation are required for accurate PFT measurements in non-cooperative subjects." | 3.88 | Apnea induction for invasive lung function testing in infant olive baboons: Comparison of intravenous propofol versus hyperventilation. ( Anderson, MP; Hill, CL; Ivanov, VA; Papin, JF; Welliver, RC; Wolf, RF, 2018) |
"We describe the characteristics of and predictors for apnea and clinical interventions during emergency department (ED) procedural sedation." | 3.83 | Characteristics of and Predictors for Apnea and Clinical Interventions During Procedural Sedation. ( Andolfatto, G; Krauss, BA; Krauss, BS; Mieloszyk, RJ; Monuteaux, MC, 2016) |
" We present a case of a 35-year-old suicidal man who developed prolonged apnea for almost 4 hours on day 13 of OP poisoning after brief general anesthesia induced by propofol and 1 mg/kg of suxamethonium, during the first session of the third cycle of modified electroconvulsive therapy, despite all due precautions." | 3.83 | Prolonged Apnea During Modified Electroconvulsive Therapy in a Patient of Suicidal Attempt by Organophosphorus Poisoning: A Case Report. ( Dhakne, R; Khairkar, P; Kumar, V; Mishra, KK, 2016) |
" The effects of isoflurane, propofol, apnea, and hypotension on lower extremity MEPs were studied." | 3.81 | Methodology of motor evoked potentials in a rabbit model. ( Bombien, R; Goodwin, E; Haji, F; Juan, V; Khoynezhad, A; Lapchak, PA; Rastegar, M; Waterford, SD, 2015) |
"Undetected apnea can lead to severe hypoxia, bradycardia, and cardiac arrest." | 3.79 | Using the entropy of tracheal sounds to detect apnea during sedation in healthy nonobese volunteers. ( Brewer, LM; Egan, TD; Hill, BE; Johnson, KB; Orr, JA; Ting, CK; Westenskow, DR; Yu, L, 2013) |
" During this period of apnea, abdominal and thoracic girth was assessed with noninvasive RIP." | 3.79 | Abdominal relaxation during emergence from general anesthesia with propofol and remifentanil. ( Atkins, JH; Mandel, JE, 2013) |
" Severe complications (reanimation, apnea, and death) were unchanged, and no patient with ASA I-II suffered from a severe complication." | 3.79 | Sedation-associated complications in endoscopy are not reduced significantly by implementation of the German S-3-guideline and occur in a severe manner only in patients with ASA class III and higher. ( Diedrich, A; Dietrich, CG; Drouven, FM; Kottmann, T, 2013) |
" Propofol's disadvantages include the induction of respiratory depression and apnea." | 3.79 | Coadministration of the AMPAKINE CX717 with propofol reduces respiratory depression and fatal apneas. ( Ding, X; Greer, JJ; Lenal, F; Ren, J; Yang, M, 2013) |
" It appeared that succinylcholine-induced apnea was responsible for the prolonged apnea." | 3.78 | Hemoglobin desaturation after propofol/remifentanil-induced apnea: a study of the recovery of spontaneous ventilation in healthy volunteers. ( Brown, R; Caldwell, JE; Feiner, J; Krombach, J; Stefanutto, TB, 2012) |
"0), during episodes of apnea, and during recovery (FiO(2) 1." | 3.77 | A novel technique for monitoring of fast variations in brain oxygen tension using an uncoated fluorescence quenching probe (Foxy AL-300). ( Boehme, S; David, M; Engelhard, K; Hartmann, EK; Klein, KU; Markstaller, K; Szczyrba, M, 2011) |
" Three horses showed apnea within a short period of time." | 3.77 | Clinical evaluation of total intravenous anesthesia using a combination of propofol and medetomidine following anesthesia induction with medetomidine, guaifenesin and propofol for castration in Thoroughbred horses. ( Kakizaki, M; Ohta, M; Oku, K; Ono, K, 2011) |
"The desaturation response time of SpO(2) to 95% after apnea was 82." | 3.76 | Comparison of desaturation and resaturation response times between transmission and reflectance pulse oximeters. ( Ahn, HJ; Choi, SJ; Kang, JG; Kang, JY; Kim, CS; Kim, JA; Kim, JK; Sim, WS; Yang, MK, 2010) |
" Hypoxemia episodes were induced by apnea alone or by apnea combined with a reduction in LV and C(RS)." | 3.75 | Targeted minute ventilation and tidal volume in an animal model of acute changes in lung mechanics and episodes of hypoxemia. ( Bancalari, E; Claure, N; D'Ugard, C; Hehre, D; Peng, J; Suguihara, C, 2009) |
" Seven of the 21 patients with Rett syndrome compared with none of the control patients experienced a serious adverse event, most of which were due to prolonged apnea (P = ." | 3.73 | Deep sedation with propofol in patients with Rett syndrome. ( Buckmaster, MA; Callans, BH; Islam, MP; Percy, AK; Tofil, NM; Winkler, MK, 2006) |
"We present a patient with myotonic dystrophy (MD) who was anesthetized with propofol using a target-controlled technique for electrophysiologic examination and cardiac catheter ablation." | 3.73 | Target-controlled infusion of propofol for a patient with myotonic dystrophy. ( Hirata, T; Matayoshi, H; Mii, M; Morimoto, Y; Sakabe, T, 2005) |
" The adverse event (AE) rate was 18% and included apnea (10%), inadequate sedation (3%), bradycardia (2%), desaturation (1%), hypotension (1%) and bag-valve-mask use (1%)." | 3.73 | Emergency department procedural sedation and analgesia: A Canadian Community Effectiveness and Safety Study (ACCESS). ( Mensour, M; Michaud, J; Pineau, R; Sahai, V, 2006) |
"We review the anesthetic implications of Joubert syndrome and report that spinal anesthesia under intravenous propofol sedation proved satisfactory for repair of an inguinal hernia in a spontaneously ventilating infant with this syndrome." | 3.72 | Anesthetic management in Joubert syndrome. ( Gordon, GJ; Vodopich, DJ, 2004) |
"Apnea was determined to be the serious adverse effect for all dogs." | 3.70 | Respiratory depression and apnea induced by propofol in dogs. ( Gadawski, JE; Muir, WW, 1998) |
" Intravenous propofol administration induced a variable period of apnea in 34 of 40 dogs." | 3.68 | Adverse effects of administration of propofol with various preanesthetic regimens in dogs. ( Bednarski, RM; Gaynor, JS; Muir, WW; Smith, JA, 1993) |
"Assessment of pain on injection of the emulsified formulation of di-isopropylphenol (propofol, 'Diprivan') was undertaken in 120 unpremedicated patients and comparison made with thiopentone." | 3.67 | Assessment and modification of pain on induction with propofol (Diprivan). ( Lees, NW; McCulloch, MJ, 1985) |
" Each dog was dosed at 1×, 2×, 5×, 10× and 20× multiples of the labelled doses (2mg/kg for alfaxalone; 6." | 2.77 | Effect of intravenous dose escalation with alfaxalone and propofol on occurrence of apnoea in the dog. ( Keates, H; Whittem, T, 2012) |
"The sevoflurane group had a lower incidence of cough than the propofol group." | 2.75 | Remifentail infusion for paediatric bronchoscopic foreign body removal: comparison of sevoflurane with propofol for anaesthesia supplementation for bronchoscope insertion. ( Li, B; Wang, Y; Zhang, J; Zhang, W, 2010) |
"Sevoflurane is an alternative to propofol for induction of anaesthesia and has a lower incidence of apnoea." | 2.71 | Comparison of propofol and sevoflurane for laryngeal mask airway insertion. ( Coskuner, I; Demirel, CB; Huseyinoglu, UA; Kati, I; Silay, E; Yagmur, C, 2003) |
"Propofol has a depressant effect on metabolic ventilatory control, causing depression of the ventilatory response to acute isocapnic hypoxia, a response mediated via the peripheral chemoreflex loop." | 2.70 | Respiratory sites of action of propofol: absence of depression of peripheral chemoreflex loop by low-dose propofol. ( Dahan, A; Kruyt, E; Nieuwenhuijs, D; Olievier, I; Sarton, E; Teppema, LJ; van Kleef, J, 2001) |
"Midazolam pretreatment was associated with a significant reduction in propofol dose requirement in both younger and older patients." | 2.70 | Effect of midazolam pretreatment on induction dose requirements of propofol in combination with fentanyl in younger and older adults. ( Bhaskaran, NC; Claydon, P; Cressey, DM; Reilly, CS, 2001) |
"Pretreatment with alfentanil also resulted in a significantly higher success rate during the first attempt at inserting the laryngeal mask airway compared with Group P (Group P 58%, Group A5 96%, Group A10 94%)." | 2.69 | Alfentanil co-induction for laryngeal mask insertion. ( Ang, S; Cheong, KF; Ng, TI, 1999) |
"Propofol was administered at 300, 600 or 1200 ml h-1 until loss of consciousness (as judged by loss of verbal contact with the patient) had been achieved." | 2.67 | Effect of different rates of infusion of propofol for induction of anaesthesia in elderly patients. ( Lewis, RP; Nimmo, WS; Peacock, JE; Reilly, CS, 1990) |
"Propofol 2." | 2.66 | The effects of premedication on anaesthesia with propofol ('Diprivan'). ( Briggs, LP; White, M, 1985) |
"Propofol is a short-acting intravenous anesthetic commonly utilised in the intensive care unit (ICU) for sedation of mechanically ventilated patients." | 2.40 | Propofol for sedation in the intensive care unit: essentials for the clinician. ( Marinella, MA, 1997) |
"Propofol was associated with a greater incidence of apnoea than thiopentone (59 per cent and 64 per cent compared with 32 per cent), but this difference was not statistically significant." | 1.31 | Effect of propofol at two injection rates or thiopentone on post-intubation apnoea in the dog. ( Murison, PJ, 2001) |
"Propofol and midazolam were compared in 40 adult patients in A." | 1.31 | A comparative study of induction and recovery characteristics of propofol and midazolam. ( Dangnan, F; Edomwonyi, NP; Okonofua, BA; Weerasinghe, AS, 2001) |
"Propofol anaesthesia was characterised by smooth rapid induction and good muscle relaxation but was only of short duration, ranging from two to seven minutes, and seemed to cause a marked respiratory depression." | 1.28 | Preliminary studies on the use of propofol in the domestic pigeon (Columba livia). ( Cooper, JE; Fitzgerald, G, 1990) |
"Propofol was used to induce and maintain anaesthesia in 20 healthy adult ASA physical status 1 patients undergoing dental surgery." | 1.28 | Pharmacodynamic properties of propofol during recovery from anaesthesia. ( Bouffier, C; François, G; Guidon-Attali, C; Lacarelle, B; Paut, O; Viviand, X, 1992) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (7.14) | 18.7374 |
1990's | 24 (21.43) | 18.2507 |
2000's | 28 (25.00) | 29.6817 |
2010's | 41 (36.61) | 24.3611 |
2020's | 11 (9.82) | 2.80 |
Authors | Studies |
---|---|
Aminnejad, R | 1 |
Hormati, A | 1 |
Shafiee, H | 1 |
Alemi, F | 1 |
Hormati, M | 1 |
Saeidi, M | 1 |
Ahmadpour, S | 1 |
Sabouri, SM | 1 |
Aghaali, M | 1 |
Gao, Y | 1 |
Yan, F | 1 |
Cuniberti, B | 1 |
Huuskonen, V | 1 |
Hughes, JL | 1 |
Walters, K | 1 |
Lehnus, K | 1 |
Liu, NC | 1 |
Bigby, SE | 3 |
Dantino, SC | 1 |
Kleine, SA | 1 |
Smith, CK | 1 |
Smith, SM | 1 |
Zhu, X | 1 |
Seddighi, R | 1 |
Wang, J | 1 |
Han, X | 1 |
Cang, J | 1 |
Miao, C | 1 |
Liang, C | 1 |
Berlin, ER | 1 |
Kinney, ME | 1 |
Howard, LL | 1 |
Perrin, KL | 1 |
Phair, KA | 1 |
Clancy, MM | 1 |
Ferris, RL | 1 |
Knych, HK | 1 |
Mama, KR | 1 |
Aljabari, S | 1 |
Ohler, A | 1 |
Waheed, S | 1 |
El-Halabi, I | 1 |
Tryon, C | 1 |
Friedman, S | 1 |
Zhang, K | 1 |
Xu, H | 1 |
Li, HT | 1 |
Tamura, J | 1 |
Oyama, N | 1 |
Fukui, S | 1 |
Yamashita, K | 1 |
Arnold, P | 1 |
Sanaulla, S | 1 |
Hampson, LV | 1 |
Davis, A | 1 |
Tan, J | 1 |
Cowen, R | 1 |
Kaleem, M | 1 |
Williams, A | 1 |
Wadsworth, I | 1 |
Jaki, T | 1 |
Beths, T | 3 |
Bauquier, S | 2 |
Carter, JE | 2 |
Ivanov, VA | 1 |
Wolf, RF | 1 |
Papin, JF | 1 |
Anderson, MP | 1 |
Hill, CL | 1 |
Welliver, RC | 1 |
Iizuka, T | 2 |
Masui, K | 2 |
Kanazawa, H | 2 |
Nishimura, R | 2 |
Tran, TT | 1 |
Beutler, SS | 1 |
Urman, RD | 1 |
Yu, L | 1 |
Ting, CK | 1 |
Hill, BE | 1 |
Orr, JA | 1 |
Brewer, LM | 1 |
Johnson, KB | 1 |
Egan, TD | 1 |
Westenskow, DR | 1 |
Ren, J | 1 |
Lenal, F | 1 |
Yang, M | 1 |
Ding, X | 1 |
Greer, JJ | 1 |
Dahan, A | 3 |
Roozekrans, M | 1 |
van der Schrier, R | 1 |
Smith, T | 1 |
Aarts, L | 2 |
Dietrich, CG | 1 |
Kottmann, T | 1 |
Diedrich, A | 1 |
Drouven, FM | 1 |
Schlag, C | 2 |
Wörner, A | 1 |
Wagenpfeil, S | 1 |
Kochs, EF | 1 |
Schmid, RM | 2 |
von Delius, S | 3 |
Friedrich-Rust, M | 1 |
Welte, M | 1 |
Welte, C | 1 |
Albert, J | 1 |
Meckbach, Y | 1 |
Herrmann, E | 1 |
Kannengiesser, M | 1 |
Trojan, J | 1 |
Filmann, N | 1 |
Schroeter, H | 1 |
Zeuzem, S | 1 |
Bojunga, J | 1 |
Kwak, HJ | 2 |
Min, SK | 1 |
Yoo, JY | 2 |
Park, KH | 1 |
Kim, JY | 2 |
Lewis, SR | 1 |
Nicholson, A | 1 |
Reed, SS | 1 |
Kenth, JJ | 1 |
Alderson, P | 1 |
Smith, AF | 1 |
Waterford, SD | 1 |
Rastegar, M | 1 |
Goodwin, E | 1 |
Lapchak, PA | 1 |
Juan, V | 1 |
Haji, F | 1 |
Bombien, R | 1 |
Khoynezhad, A | 1 |
Klare, P | 1 |
Huth, R | 1 |
Haller, B | 1 |
Huth, M | 1 |
Weber, A | 1 |
Reindl, W | 1 |
Dhakne, R | 1 |
Mishra, KK | 1 |
Kumar, V | 1 |
Khairkar, P | 1 |
Ferguson, I | 1 |
Bell, A | 1 |
Treston, G | 1 |
New, L | 1 |
Ding, M | 1 |
Holdgate, A | 1 |
Krauss, BS | 1 |
Andolfatto, G | 1 |
Krauss, BA | 1 |
Mieloszyk, RJ | 1 |
Monuteaux, MC | 1 |
Kim, YB | 1 |
Park, CK | 1 |
Lee, SY | 1 |
Riphaus, A | 1 |
Wehrmann, T | 1 |
Kronshage, T | 1 |
Geist, C | 1 |
Pox, CP | 1 |
Heringlake, S | 1 |
Schmiegel, W | 1 |
Beitz, A | 1 |
Meining, A | 1 |
Müller, M | 1 |
Ye, L | 1 |
Xiao, X | 1 |
Zhu, L | 1 |
Miyabe-Nishiwaki, T | 1 |
Xu, ZY | 1 |
Wang, X | 1 |
Si, YY | 1 |
Wu, JC | 1 |
Zuo, YX | 1 |
Xue, FS | 2 |
Liu, J | 2 |
Claure, N | 1 |
Suguihara, C | 1 |
Peng, J | 1 |
Hehre, D | 1 |
D'Ugard, C | 1 |
Bancalari, E | 1 |
Lerman, J | 1 |
Houle, TT | 1 |
Matthews, BT | 1 |
Houck, J | 1 |
Burrows, FA | 1 |
Jeon, WJ | 1 |
Kim, KH | 1 |
Suh, JK | 1 |
Cho, SY | 1 |
Bryan, YF | 1 |
Hoke, LK | 1 |
Taghon, TA | 1 |
Nick, TG | 1 |
Wang, Y | 2 |
Kennedy, SM | 1 |
Furstein, JS | 1 |
Kurth, CD | 1 |
Choi, SJ | 2 |
Ahn, HJ | 1 |
Yang, MK | 1 |
Kim, CS | 1 |
Sim, WS | 1 |
Kim, JA | 2 |
Kang, JG | 1 |
Kim, JK | 1 |
Kang, JY | 1 |
Changchien, CF | 1 |
Chen, HS | 1 |
Hsieh, SW | 1 |
Tan, PH | 1 |
Lin, VC | 1 |
Liu, CC | 1 |
Liu, PH | 1 |
Hung, KC | 1 |
Tan, AS | 1 |
Wang, CY | 1 |
Cacho, G | 1 |
Pérez-Calle, JL | 1 |
Barbado, A | 1 |
Lledó, JL | 1 |
Ojea, R | 1 |
Fernández-Rodríguez, CM | 1 |
Olofsen, E | 1 |
Boom, M | 1 |
Nieuwenhuijs, D | 2 |
Sarton, E | 2 |
Teppema, L | 1 |
Hirsh, I | 1 |
Lerner, A | 1 |
Shnaider, I | 1 |
Reuveni, A | 1 |
Pacht, A | 1 |
Segol, O | 1 |
Pizov, R | 1 |
Zhang, J | 1 |
Li, B | 1 |
Zhang, W | 1 |
Yuan, YJ | 1 |
Wang, Q | 1 |
Liu, JH | 1 |
Liao, X | 1 |
Marcos Vidal, JM | 1 |
Bermejo González, JC | 1 |
Baticón Escudero, PM | 1 |
Oku, K | 1 |
Kakizaki, M | 1 |
Ono, K | 1 |
Ohta, M | 1 |
Klein, KU | 1 |
Boehme, S | 1 |
Hartmann, EK | 1 |
Szczyrba, M | 1 |
David, M | 1 |
Markstaller, K | 1 |
Engelhard, K | 1 |
Keates, H | 1 |
Whittem, T | 1 |
Levitzky, BE | 1 |
Lopez, R | 2 |
Dumot, JA | 1 |
Vargo, JJ | 2 |
Stefanutto, TB | 1 |
Feiner, J | 1 |
Krombach, J | 1 |
Brown, R | 1 |
Caldwell, JE | 1 |
Kopman, AF | 1 |
Kurata, J | 1 |
Erdogan, MA | 1 |
Begec, Z | 1 |
Aydogan, MS | 1 |
Ozgul, U | 1 |
Yucel, A | 1 |
Colak, C | 1 |
Durmus, M | 1 |
Wang, D | 1 |
Chen, C | 1 |
Chen, J | 2 |
Xu, Y | 1 |
Wang, L | 1 |
Zhu, Z | 1 |
Deng, D | 1 |
Long, A | 1 |
Tang, D | 1 |
Atkins, JH | 1 |
Mandel, JE | 1 |
Bloomfield, EL | 1 |
Murray, MJ | 1 |
Kati, I | 1 |
Demirel, CB | 1 |
Huseyinoglu, UA | 1 |
Silay, E | 1 |
Yagmur, C | 1 |
Coskuner, I | 1 |
Vodopich, DJ | 1 |
Gordon, GJ | 1 |
Frazee, BW | 1 |
Park, RS | 1 |
Lowery, D | 1 |
Baire, M | 1 |
Siddik-Sayyid, SM | 1 |
Aouad, MT | 1 |
Taha, SK | 1 |
Daaboul, DG | 1 |
Deeb, PG | 1 |
Massouh, FM | 1 |
Muallem, MA | 1 |
Baraka, AS | 1 |
Akin, A | 1 |
Esmaoglu, A | 1 |
Tosun, Z | 1 |
Gulcu, N | 1 |
Aydogan, H | 1 |
Boyaci, A | 1 |
El-Orbany, MI | 1 |
Joseph, NJ | 1 |
Salem, MR | 1 |
Morimoto, Y | 1 |
Mii, M | 1 |
Hirata, T | 1 |
Matayoshi, H | 1 |
Sakabe, T | 1 |
Qadeer, MA | 1 |
Khandwala, F | 1 |
Zuccaro, G | 1 |
Oberer, C | 1 |
von Ungern-Sternberg, BS | 1 |
Frei, FJ | 1 |
Erb, TO | 1 |
Musk, GC | 1 |
Pang, DS | 1 |
Flaherty, DA | 1 |
Parlak, M | 1 |
Parlak, I | 1 |
Erdur, B | 1 |
Ergin, A | 1 |
Sagiroglu, E | 1 |
Tofil, NM | 1 |
Buckmaster, MA | 1 |
Winkler, MK | 1 |
Callans, BH | 1 |
Islam, MP | 1 |
Percy, AK | 1 |
Yu, AL | 1 |
Critchley, LA | 1 |
Lee, A | 1 |
Gin, T | 2 |
Mensour, M | 1 |
Pineau, R | 1 |
Sahai, V | 1 |
Michaud, J | 1 |
Lee, SM | 1 |
Kim, GH | 1 |
Lee, JJ | 1 |
Kim, GS | 1 |
Jung, HH | 1 |
Hong, JY | 1 |
Kang, YS | 1 |
Kil, HK | 1 |
Lieblich, SE | 1 |
Hui, TW | 1 |
Short, TG | 1 |
Hong, W | 1 |
Suen, T | 1 |
Plummer, J | 1 |
Sun, KO | 1 |
Smith, JA | 1 |
Gaynor, JS | 1 |
Bednarski, RM | 1 |
Muir, WW | 2 |
Karlsten, R | 1 |
Englesson, S | 1 |
Cheng, DC | 1 |
Karski, J | 1 |
Peniston, C | 1 |
Asokumar, B | 1 |
Raveendran, G | 1 |
Carroll, J | 1 |
Nierenberg, H | 1 |
Roger, S | 1 |
Mickle, D | 1 |
Tong, J | 1 |
Zelovitsky, J | 1 |
David, T | 1 |
Sandler, A | 1 |
Spens, HJ | 1 |
Drummond, GB | 2 |
Bowdle, TA | 1 |
Camporesi, EM | 1 |
Maysick, L | 1 |
Hogue, CW | 1 |
Miguel, RV | 1 |
Pitts, M | 1 |
Streisand, JB | 1 |
el-Farhan, NM | 1 |
Pablo, LS | 1 |
Bailey, JE | 1 |
Ko, JC | 1 |
Marinella, MA | 1 |
Gadawski, JE | 1 |
Ang, S | 1 |
Cheong, KF | 1 |
Ng, TI | 1 |
Goto, T | 1 |
Nakata, Y | 1 |
Uezono, S | 1 |
Niimi, Y | 1 |
Uchiyama, M | 1 |
Morita, S | 1 |
Voyagis, GS | 1 |
Dimitriou, V | 1 |
Kostantopoulou, G | 1 |
Charissi, N | 1 |
Cressey, DM | 1 |
Claydon, P | 1 |
Bhaskaran, NC | 1 |
Reilly, CS | 3 |
Yeo, KS | 1 |
Kua, SW | 1 |
Teoh, GS | 1 |
Onsiong, MK | 1 |
Murison, PJ | 1 |
Edomwonyi, NP | 1 |
Okonofua, BA | 1 |
Weerasinghe, AS | 1 |
Dangnan, F | 1 |
Teppema, LJ | 1 |
Kruyt, E | 1 |
Olievier, I | 1 |
van Kleef, J | 1 |
Kaddu, R | 1 |
Bhattacharya, D | 1 |
Metriyakool, K | 1 |
Thomas, R | 1 |
Tolia, V | 1 |
Henderson, F | 1 |
Absalom, AR | 1 |
Kenny, GN | 1 |
Paut, O | 1 |
Guidon-Attali, C | 1 |
Viviand, X | 1 |
Lacarelle, B | 1 |
Bouffier, C | 1 |
François, G | 1 |
Reddy, RV | 1 |
Moorthy, SS | 1 |
Dierdorf, SF | 1 |
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Huyghe, L | 1 |
Mungroop, H | 1 |
Robinson, FP | 1 |
Briggs, LP | 1 |
White, M | 1 |
McCulloch, MJ | 1 |
Lees, NW | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Development of an Algorithm That Predicts Hypoventilation Due to an Opioid Overdose[NCT03845699] | 20 participants (Anticipated) | Observational | 2019-05-15 | Recruiting | |||
Development of a Tracheal Sound Sensor for Early Detection of Hypoventilation[NCT05506267] | 20 participants (Actual) | Observational | 2020-06-01 | Completed | |||
[NCT02001792] | 412 participants (Actual) | Interventional | 2012-04-30 | Completed | |||
Prospective Observational Evaluation of a New Protocol for Adult Procedural Sedation With Ketamine-propofol in a 1 on 4 Ratio at the Emergency Department of a Tertiary Hospital[NCT04028141] | 61 participants (Actual) | Observational | 2018-02-01 | Completed | |||
Intravenous Sedation and Analgesia Using Propofol, Fentanyl and Ketamine (PFK) Versus General Anesthesia in Minor Urological Procedures.[NCT04285528] | 200 participants (Actual) | Interventional | 2019-04-17 | Completed | |||
Importance of Integrated Pulmonary Index in Pediatric Patients Undergoing Bronchoscopy Procedures Under Sedation[NCT05137587] | 60 participants (Actual) | Interventional | 2022-09-01 | Completed | |||
The Value of Integrated Pulmonary Index Monitoring[NCT05356819] | 154 participants (Actual) | Interventional | 2018-10-01 | Completed | |||
Importance of Integrated Pulmonary Index in Pediatric Patients Undergoing Endoscopy Procedures Under Sedation[NCT05137574] | 60 participants (Actual) | Interventional | 2021-05-10 | Completed | |||
Safety and Efficacy Evaluation of Remimazolam for Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy[NCT05437497] | 264 participants (Anticipated) | Interventional | 2021-08-01 | Recruiting | |||
Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists - a Study in Opioid naïve Individuals and Chronic Opioid Users Under Real-life Conditions[NCT05338632] | Phase 1 | 24 participants (Anticipated) | Interventional | 2022-06-24 | Recruiting | ||
Goal Directed Propofol Sedation With Magnesium Sulphate Versus Dexmedetomidine for ERCP Procedure[NCT02684019] | Phase 3 | 60 participants (Actual) | Interventional | 2016-01-31 | Completed | ||
An Observer Rating Scale of Facial Expression Can Predict Dreaming in Propofol Anesthesia[NCT04235894] | 124 participants (Actual) | Observational | 2016-09-07 | Completed | |||
Low Dose Fentanyl/Midazolam Improves Sevoflurane Induction in Adults[NCT00723164] | 80 participants (Actual) | Interventional | 2005-10-31 | Completed | |||
Evaluation of the Effectiveness and Safety of Endotracheal Intubation for Inhalational Anesthesia Without the Use of Muscle Relaxants or Analgesics[NCT03112564] | 91 participants (Actual) | Interventional | 2013-03-01 | Completed | |||
Comparison of Ketamine Versus Co-Administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department[NCT01387139] | Phase 3 | 183 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
[NCT02039453] | 160 participants (Anticipated) | Interventional | 2013-09-30 | Recruiting | |||
A Psychomotor Recuperation Study After Deep Sedation for Colonoscopy Between Target Controlled and Manual Titration of Propofol.[NCT02314559] | Phase 4 | 164 participants (Actual) | Interventional | 2015-02-28 | Completed | ||
Impact of High Concentrations of Sevoflurane on Laryngeal Reflex Responses in Pediatric Patients[NCT00665418] | Phase 4 | 40 participants (Actual) | Interventional | 2008-02-29 | Terminated (stopped due to Recruitment finished earlier, because all 40 patients enrolled) | ||
Impact of Remifentanil Administration on Laryngeal Reflex Responses in Pediatric Patients With Upper Respiratory Anesthetized With Propofol[NCT00611195] | Phase 4 | 62 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
EEG to Monitor Propofol Anesthetic Depth in Infants and Toddlers[NCT05701748] | 120 participants (Anticipated) | Interventional | 2023-02-03 | Recruiting | |||
Comparison Of Different Anesthetic Techniques In Children Undergoing Esophagogastroduodenoscopies[NCT02038894] | 179 participants (Actual) | Interventional | 2009-12-31 | Completed | |||
Fiberoptic Bronchoscopy With Broncho-alveolar Lavage Under Noninvasive Ventilation With Propofol Target Controled Infusion in Patient With Acute Hypoxemic Respiratory Failure. A Randomized Controlled Study : SEDA-FIBRO.[NCT00741949] | Phase 3 | 46 participants (Anticipated) | Interventional | 2008-09-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
"Efficacy is defined as:~The patient does not have unpleasant recall of the procedure.~The patient did not experience sedation-related adverse events resulting in abandonment of the procedure or a permanent complication or an unplanned admission to the hospital or prolonged emergency department (ED) observation~The patient did not actively resist or require physical restraint for completion of the procedure. The need for minimal redirection of movements should not be considered as active resistance or physical restraint.~The procedure was successful" (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | participants (Number) |
---|---|
Ketamine Alone | 97 |
Ketamine Co-Administered With Propofol | 81 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | units on a scale (Median) |
---|---|
Ketamine Alone | 10 |
Ketamine Co-Administered With Propofol | 8 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | units on a scale (1-10) (Median) |
---|---|
Ketamine Alone | 10 |
Ketamine Co-Administered With Propofol | 10 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | units on a scale (Median) |
---|---|
Ketamine Alone | 9 |
Ketamine Co-Administered With Propofol | 8 |
Time until the patient has a Vancouver Sedation Recovery Scale Score of 18 or greater. (NCT01387139)
Timeframe: Once Vancouver Sedation Recovery Scale Score reaches 18 or greater, on average less than 1 hour
Intervention | minutes (Median) |
---|---|
Ketamine Alone | 44 |
Ketamine Co-Administered With Propofol | 43.5 |
We will record all adverse events during the sedation, and then perform a follow-up call to determine if any additional adverse events occured after discharge. (NCT01387139)
Timeframe: From enrollment through completion of follow-up, up to 7 days
Intervention | participants (Number) | |||
---|---|---|---|---|
Respiratory depression | Cardiovascular event | vomiting/retching | Unpleasant recovery reaction | |
Ketamine Alone | 12 | 1 | 21 | 4 |
Ketamine Co-Administered With Propofol | 15 | 0 | 18 | 2 |
An important outcome in the anesthetic management of these patients is to maintain a balance between a safe technique with a minimal incidence of respiratory complications, and a technique that facilitates rapid turnover of the gastrointestinal suite. A chi-square test, or Fisher's exact test will measure differences among the three anesthetic groups. Different anesthetic techniques are currently in use at Cincinnati Children's Hospital Medical Center (CCHMC). Because there is a lack of evidence to delineate the best techniques, pediatric anesthesiologists select the technique based on clinical preference and experience. (NCT02038894)
Timeframe: Admission for surgery through recovery period, approximately 3 hours
Intervention | Participants (Count of Participants) | ||||
---|---|---|---|---|---|
SPO2 < 95% | SPO2 < 85% | Apnea | Inadequate Anesthesia | All Respiratory Events | |
Intubated With Propofol (IP) | 0 | 0 | 1 | 4 | 5 |
Intubated With Sevoflurane (IS) | 0 | 0 | 0 | 1 | 2 |
IP and NA | 15 | 8 | 5 | 13 | 32 |
IS and IP | 0 | 0 | 1 | 5 | 7 |
Native Airway - no Intubation | 15 | 9 | 5 | 9 | 28 |
Time measurements are used to evaluate the efficiency of the different techniques. We will compare the times spent in the operating room and the postoperative unit for each technique. (NCT02038894)
Timeframe: Admission for surgery through recovery period, approximately 3 hours
Intervention | Minutes (Mean) | ||||
---|---|---|---|---|---|
OR Time | Anesthesia Preparation Time | Procedural Time | PACU efficiency time | Total Perioperative Time | |
Intubated With Propofol (IP) | 24.19 | 10.70 | 9.23 | 53.49 | 79.61 |
Intubated With Sevoflurane (IS) | 24.03 | 10.86 | 9.07 | 49.50 | 75.34 |
IP and NA | 23.61 | 10.53 | 8.78 | 53.96 | 79.49 |
IS and IP | 24.11 | 10.78 | 9.15 | 51.48 | 77.46 |
Native Airway - no Intubation | 23.05 | 10.35 | 8.33 | 54.42 | 79.37 |
8 reviews available for propofol and Apnea
Article | Year |
---|---|
Safety and efficacy of propofol alone or in combination with other agents for sedation of patients undergoing colonoscopy: an updated meta-analysis.
Topics: Apnea; Colonoscopy; Deep Sedation; Drug Therapy, Combination; Humans; Hypnotics and Sedatives; Hypot | 2020 |
Moderate and deep sedation training and pharmacology for nonanesthesiologists: recommendations for effective practice.
Topics: Administration, Intravenous; Analgesics, Opioid; Anesthesiology; Apnea; Benzodiazepines; Conscious S | 2019 |
Anaesthetic and sedative agents used for electrical cardioversion.
Topics: Anesthetics; Apnea; Diazepam; Electric Countershock; Etomidate; Fentanyl; Humans; Hypnotics and Seda | 2015 |
The Comparison of Etomidate and Propofol Anesthesia in Patients Undergoing Gastrointestinal Endoscopy: A Systematic Review and Meta-Analysis.
Topics: Anesthesia Recovery Period; Anesthetics, Intravenous; Apnea; Arterial Pressure; Colonoscopy; Endosco | 2017 |
The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis.
Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Huma | 2013 |
The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis.
Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Huma | 2013 |
The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis.
Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Huma | 2013 |
The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis.
Topics: Adult; Aged; Anesthesia, Intravenous; Apnea; Arrhythmias, Cardiac; Endoscopy, Gastrointestinal; Huma | 2013 |
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy | 2005 |
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy | 2005 |
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy | 2005 |
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy | 2005 |
Methohexital versus propofol for outpatient anesthesia. Part I: Methohexital is superior.
Topics: Akathisia, Drug-Induced; Ambulatory Surgical Procedures; Anesthesia, Dental; Apnea; Drug Costs; Endo | 1995 |
Propofol for sedation in the intensive care unit: essentials for the clinician.
Topics: Adult; Aged; Apnea; Bradycardia; Critical Care; Drug Administration Schedule; Half-Life; Humans; Hyp | 1997 |
59 trials available for propofol and Apnea
Article | Year |
---|---|
Comparing the Efficacy and Safety of Dexmedetomidine/Ketamine with Propofol/Fentanyl for Sedation in Colonoscopy Patients: A Doubleblinded Randomized Clinical Trial.
Topics: Apnea; Colonoscopy; Dexmedetomidine; Double-Blind Method; Fentanyl; Humans; Hypnotics and Sedatives; | 2022 |
Comparison of Intra and Post-operative Sedation Efficacy of Dexmedetomidinemidazolam and Dexmedetomidine-propofol for Major Abdominal Surgery.
Topics: Anesthesia; Apnea; Dexmedetomidine; Humans; Hypertension; Hypnotics and Sedatives; Hypotension; Hypo | 2022 |
Comparison between continuous rate infusion and target-controlled infusion of propofol in dogs: a randomized clinical trial.
Topics: Anesthetics, Intravenous; Animals; Apnea; Dog Diseases; Dogs; Hypotension; Propofol; Prospective Stu | 2023 |
Determining an optimum propofol infusion rate for induction of anaesthesia in healthy dogs: a randomized clinical trial.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Apnea; Dog Diseases; Dogs; Propofol; Prospective Stud | 2022 |
Rapid sequence induction with a "modified timing principle" of rocuronium provides excellent intubating conditions: A randomised trial.
Topics: Androstanols; Apnea; Humans; Intubation, Intratracheal; Neuromuscular Nondepolarizing Agents; Propof | 2022 |
Postinduction apnoea in dogs premedicated with acepromazine or dexmedetomidine and anaesthetized with alfaxalone or propofol.
Topics: Acepromazine; Anesthesia, General; Anesthetics, Combined; Animals; Apnea; Carbon Dioxide; Dexmedetom | 2017 |
Effect of rate of administration of propofol or alfaxalone on induction dose requirements and occurrence of apnea in dogs.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Apnea; Dogs; Female; Male; Preanesthetic | 2017 |
Capnography improves detection of apnea during procedural sedation for percutaneous transhepatic cholangiodrainage.
Topics: Aged; Apnea; Capnography; Conscious Sedation; Digestive System Surgical Procedures; Female; Germany; | 2013 |
Capnographic monitoring of propofol-based sedation during colonoscopy.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Apnea; Body Mass Index; Capnography; Colono | 2014 |
The median effective dose of dexmedetomidine for laryngeal mask airway insertion with propofol 2.0 mg/kg.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adult; Analgesics, Non-Narcotic; Anesthetics, Intr | 2014 |
Patient position and hypoxemia during propofol sedation for colonoscopy: a randomized trial.
Topics: Adenoma; Adult; Aged; Apnea; Colonic Neoplasms; Colonoscopy; Conscious Sedation; Female; Humans; Hyp | 2015 |
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr | 2016 |
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr | 2016 |
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr | 2016 |
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr | 2016 |
The effect of dexmedetomidine pretreatment on the median effective bolus dose of propofol for facilitating laryngeal mask airway insertion.
Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Apnea; Dexmedetomidine; Female; Hemodynam | 2017 |
Clinical value of the Integrated Pulmonary Index
Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema | 2017 |
Clinical value of the Integrated Pulmonary Index
Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema | 2017 |
Clinical value of the Integrated Pulmonary Index
Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema | 2017 |
Clinical value of the Integrated Pulmonary Index
Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema | 2017 |
Clinical value of the Integrated Pulmonary Index
Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema | 2017 |
Clinical value of the Integrated Pulmonary Index
Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema | 2017 |
Clinical value of the Integrated Pulmonary Index
Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema | 2017 |
Clinical value of the Integrated Pulmonary Index
Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema | 2017 |
Clinical value of the Integrated Pulmonary Index
Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema | 2017 |
Intravenous remifentanil and propofol for gastroscopy.
Topics: Adult; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Intravenous; Apnea; Cognition | 2008 |
Propofol for tracheal intubation in children anesthetized with sevoflurane: a dose-response study.
Topics: Adenoidectomy; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Inhalation; Apnea; Child; | 2009 |
The use of remifentanil to facilitate the insertion of the Cobra perilaryngeal airway.
Topics: Adult; Anesthesia, General; Anesthetics, Combined; Anesthetics, Intravenous; Apnea; Blood Pressure; | 2009 |
A randomized trial comparing sevoflurane and propofol in children undergoing MRI scans.
Topics: Algorithms; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhal | 2009 |
Topical lidocaine improves conditions for laryngeal mask airway insertion.
Topics: Administration, Topical; Adult; Anesthetics, Intravenous; Anesthetics, Local; Apnea; Blood Pressure; | 2010 |
Fentanyl dose for the insertion of Classic Laryngeal Mask Airways in non-paralysed patients induced with propofol 2.5 mg/kg.
Topics: Adult; Analgesics, Opioid; Anesthesia, Intravenous; Anesthetics, Intravenous; Apnea; Female; Fentany | 2010 |
Capnography is superior to pulse oximetry for the detection of respiratory depression during colonoscopy.
Topics: Adult; Aged; Apnea; Capnography; Carbon Dioxide; Colonoscopy; Computer Systems; Conscious Sedation; | 2010 |
Modeling the non-steady state respiratory effects of remifentanil in awake and propofol-sedated healthy volunteers.
Topics: Adolescent; Adult; Apnea; Humans; Hypnotics and Sedatives; Infusion Pumps; Male; Models, Biological; | 2010 |
Remifentanil versus fentanyl for esophagogastroduodenoscopy in children.
Topics: Analgesics, Opioid; Apnea; Child; Endoscopy, Digestive System; Female; Fentanyl; Hemodynamics; Human | 2010 |
Remifentail infusion for paediatric bronchoscopic foreign body removal: comparison of sevoflurane with propofol for anaesthesia supplementation for bronchoscope insertion.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Apnea; Blood Pressure; Bronchoscopy; Child, Presc | 2010 |
Effect of intravenous dose escalation with alfaxalone and propofol on occurrence of apnoea in the dog.
Topics: Anesthetics, Intravenous; Animals; Apnea; Cross-Over Studies; Dogs; Dose-Response Relationship, Drug | 2012 |
Moderate sedation for elective upper endoscopy with balanced propofol versus fentanyl and midazolam alone: a randomized clinical trial.
Topics: Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Apnea; Deep Sedation; Endoscopy, Digesti | 2012 |
Comparison of effects of propofol and ketamine-propofol mixture (ketofol) on laryngeal mask airway insertion conditions and hemodynamics in elderly patients: a randomized, prospective, double-blind trial.
Topics: Aged; Anesthesia, Inhalation; Anesthetics, Dissociative; Anesthetics, Intravenous; Apnea; Blood Pres | 2013 |
Comparison of propofol and sevoflurane for laryngeal mask airway insertion.
Topics: Adult; Analysis of Variance; Anesthetics, Inhalation; Anesthetics, Intravenous; Apnea; Blood Pressur | 2003 |
Propofol for deep procedural sedation in the ED.
Topics: Adolescent; Adult; Analgesics, Opioid; Apnea; Conscious Sedation; Dose-Response Relationship, Drug; | 2005 |
A comparison of sevoflurane-propofol versus sevoflurane or propofol for laryngeal mask airway insertion in adults.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Apn | 2005 |
A comparison of sevoflurane-propofol versus sevoflurane or propofol for laryngeal mask airway insertion in adults.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Apn | 2005 |
A comparison of sevoflurane-propofol versus sevoflurane or propofol for laryngeal mask airway insertion in adults.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Apn | 2005 |
A comparison of sevoflurane-propofol versus sevoflurane or propofol for laryngeal mask airway insertion in adults.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Apn | 2005 |
Comparison of propofol with propofol-ketamine combination in pediatric patients undergoing auditory brainstem response testing.
Topics: Adolescent; Anesthetics, Intravenous; Apnea; Blood Pressure; Child; Child, Preschool; Drug Combinati | 2005 |
Tracheal intubating conditions and apnoea time after small-dose succinylcholine are not modified by the choice of induction agent.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, General; Apnea; Dose-Response Relationship, | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Respiratory reflex responses of the larynx differ between sevoflurane and propofol in pediatric patients.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2005 |
Target-controlled infusion of propofol in dogs--evaluation of four targets for induction of anaesthesia.
Topics: Anesthetics, Intravenous; Animals; Apnea; Blood Pressure; Dog Diseases; Dogs; Dose-Response Relation | 2005 |
Age effect on efficacy and side effects of two sedation and analgesia protocols on patients going through cardioversion: a randomized clinical trial.
Topics: Age Factors; Aged; Analgesia; Anesthesia Recovery Period; Anesthetics, Intravenous; Apnea; Blood Pre | 2006 |
Alfentanil dosage when inserting the classic laryngeal mask airway.
Topics: Adolescent; Adult; Alfentanil; Anesthesia, General; Anesthetics, Intravenous; Apnea; Data Interpreta | 2006 |
Anaesthesia for day case excisional breast biopsy: propofol-remifentanil compared with sevoflurane-nitrous oxide.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, | 2008 |
Additive interactions between propofol and ketamine when used for anesthesia induction in female patients.
Topics: Adult; Age Factors; Anesthesia, Intravenous; Apnea; Blood Pressure; Body Weight; Dose-Response Relat | 1995 |
Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial.
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Apnea; Catecholamines; | 1996 |
Ventilatory effects of eltanolone during induction of anaesthesia: comparison with propofol and thiopentone.
Topics: Adolescent; Adult; Anesthetics, Intravenous; Apnea; Female; Humans; Male; Middle Aged; Postoperative | 1996 |
A multicenter evaluation of remifentanil for early postoperative analgesia.
Topics: Abdomen; Adult; Aged; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Intravenous; Anest | 1996 |
Do anxiety or hypocapnia predispose to apnoea after induction of anaesthesia?
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Anxiety; Apnea; Etomidate; Female; Humans; | 1997 |
Median effective dose of propofol required for induction of anaesthesia in goats.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Apnea; Dose-Response Relationship, Drug; | 1997 |
Alfentanil co-induction for laryngeal mask insertion.
Topics: Adult; Alfentanil; Analgesics, Opioid; Anesthesia; Anesthetics, Combined; Anesthetics, Intravenous; | 1999 |
Insertion of the cuffed oropharyngeal airway (COPA) with propofol or sevoflurane in adults.
Topics: Adult; Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Apnea; Chi-Square Distribution; Coug | 1999 |
Comparison between two different propofol dosage regimens for insertion of cuffed oro-pharyngeal airway.
Topics: Adult; Aged; Anesthetics, Intravenous; Apnea; Female; Humans; Intubation, Intratracheal; Male; Middl | 1999 |
Effect of midazolam pretreatment on induction dose requirements of propofol in combination with fentanyl in younger and older adults.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Aging; Analysis of Variance; Anesthetics, Intravenou | 2001 |
The use of thiopentone/propofol admixture for laryngeal mask airway insertion.
Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Apnea; Double | 2001 |
Respiratory sites of action of propofol: absence of depression of peripheral chemoreflex loop by low-dose propofol.
Topics: Adolescent; Adult; Algorithms; Anesthetics, Intravenous; Apnea; Carbon Dioxide; Chemoreceptor Cells; | 2001 |
Propofol compared with general anesthesia for pediatric GI endoscopy: is propofol better?
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anes | 2002 |
Patient-maintained propofol sedation: a follow up safety study using a modified system in volunteers.
Topics: Adult; Apnea; Conscious Sedation; Drug Administration Schedule; Female; Follow-Up Studies; Humans; H | 2002 |
Induction dose-response of propofol in unpremedicated children.
Topics: Age Factors; Anesthesia, Intravenous; Apnea; Child; Child, Preschool; Dose-Response Relationship, Dr | 1992 |
Changes in oxygen saturation following propofol induction of anaesthesia at different rates in the elderly.
Topics: Aged; Anesthesia, Intravenous; Apnea; Fentanyl; Humans; Oximetry; Oxygen; Oxygen Consumption; Propof | 1991 |
Etomidate vs. propofol to carry out suspension laryngoscopies.
Topics: Alfentanil; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthesia, Local; Apnea; Conscious | 1991 |
Effect of different rates of infusion of propofol for induction of anaesthesia in elderly patients.
Topics: Aged; Anesthesia, General; Apnea; Blood Pressure; Female; Heart Rate; Humans; Male; Propofol; Time F | 1990 |
Effects of alfentanil on induction and recovery from propofol anaesthesia in day surgery.
Topics: Adult; Alfentanil; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Intraveno | 1990 |
Comparison of the induction characteristics of thiopentone and propofol in children.
Topics: Adolescent; Anesthesia, Intravenous; Anesthetics; Apnea; Blood Pressure; Child; Child, Preschool; De | 1987 |
Effect of speed of injection on induction of anaesthesia using propofol.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics; Apnea; Blood Pressure; Female; Humans; In | 1985 |
The effects of premedication on anaesthesia with propofol ('Diprivan').
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Apnea; Atropine; Blood Pressure; Diazepam; Female; | 1985 |
45 other studies available for propofol and Apnea
Article | Year |
---|---|
Effects of intravenous acepromazine and butorphanol on propofol dosage for induction of anesthesia in healthy Beagle dogs.
Topics: Acepromazine; Anesthesia; Animals; Apnea; Butorphanol; Dog Diseases; Dogs; Female; Hypotension; Male | 2022 |
Pharmacokinetics of intravenous propofol in southern white rhinoceros (Ceratotherium simum simum) after intramuscular etorphine-butorphanol-medetomidine-azaperone.
Topics: Animals; Apnea; Azaperone; Butorphanol; Etorphine; Female; Hypnotics and Sedatives; Medetomidine; Pe | 2023 |
Topical Pharyngeal Anesthesia in Sedated Pediatric Patients Undergoing Esophagogastroduodenoscopy.
Topics: Airway Obstruction; Anesthesia; Apnea; Benzocaine; Child; Conscious Sedation; Endoscopy, Digestive S | 2023 |
Comparison of the anesthetic effects between 5 mg/kg of alfaxalone and 10 mg/kg of propofol administered intravenously in cats.
Topics: Anesthetics; Animals; Apnea; Cat Diseases; Cats; Pregnanediones; Propofol | 2021 |
Study to evaluate the optimal dose of remifentanil required to ensure apnea during magnetic resonance imaging of the heart under general anesthesia.
Topics: Anesthesia, General; Anesthetics, Intravenous; Apnea; Bayes Theorem; Child; Child, Preschool; Humans | 2021 |
Apnea induction for invasive lung function testing in infant olive baboons: Comparison of intravenous propofol versus hyperventilation.
Topics: Anesthetics, Intravenous; Animals; Animals, Newborn; Ape Diseases; Apnea; Female; Hyperventilation; | 2018 |
Comparison of plasma propofol concentration for apnea, response to mechanical ventilation, and airway device between endotracheal tube and supraglottic airway device in Beagles.
Topics: Animals; Apnea; Dogs; Intubation, Intratracheal; Propofol; Respiration, Artificial | 2018 |
Using the entropy of tracheal sounds to detect apnea during sedation in healthy nonobese volunteers.
Topics: Adult; Anesthetics, Intravenous; Apnea; Entropy; Female; Humans; Male; Piperidines; Propofol; Refere | 2013 |
Using the entropy of tracheal sounds to detect apnea during sedation in healthy nonobese volunteers.
Topics: Adult; Anesthetics, Intravenous; Apnea; Entropy; Female; Humans; Male; Piperidines; Propofol; Refere | 2013 |
Using the entropy of tracheal sounds to detect apnea during sedation in healthy nonobese volunteers.
Topics: Adult; Anesthetics, Intravenous; Apnea; Entropy; Female; Humans; Male; Piperidines; Propofol; Refere | 2013 |
Using the entropy of tracheal sounds to detect apnea during sedation in healthy nonobese volunteers.
Topics: Adult; Anesthetics, Intravenous; Apnea; Entropy; Female; Humans; Male; Piperidines; Propofol; Refere | 2013 |
Coadministration of the AMPAKINE CX717 with propofol reduces respiratory depression and fatal apneas.
Topics: Anesthetics, Intravenous; Animals; Animals, Newborn; Apnea; Disease Models, Animal; Drug Therapy, Co | 2013 |
Primum non nocere or how to resolve drug-induced respiratory depression.
Topics: Anesthetics, Intravenous; Animals; Apnea; Isoxazoles; Male; Propofol; Respiratory Insufficiency | 2013 |
Sedation-associated complications in endoscopy are not reduced significantly by implementation of the German S-3-guideline and occur in a severe manner only in patients with ASA class III and higher.
Topics: Antidotes; Apnea; Critical Care; Deep Sedation; Delivery of Health Care; Endoscopy, Gastrointestinal | 2013 |
Methodology of motor evoked potentials in a rabbit model.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Apnea; Disease Models, Animal; Evoked Po | 2015 |
Prolonged Apnea During Modified Electroconvulsive Therapy in a Patient of Suicidal Attempt by Organophosphorus Poisoning: A Case Report.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Apnea; Bipolar Disorder; Humans; Male; Neu | 2016 |
Characteristics of and Predictors for Apnea and Clinical Interventions During Procedural Sedation.
Topics: Adult; Aged; Apnea; Capnography; Conscious Sedation; Female; Heart Rate; Humans; Hypnotics and Sedat | 2016 |
Propofol-fentanyl interaction in Beagles - Apnea, response to mechanical ventilation, endotracheal tube, and tetanic stimulation.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Animals; Apnea; Dogs; Female; Fentanyl; Hypnotics and | 2017 |
Targeted minute ventilation and tidal volume in an animal model of acute changes in lung mechanics and episodes of hypoxemia.
Topics: Animals; Apnea; Calibration; Disease Models, Animal; Hypoxia; Intermittent Positive-Pressure Ventila | 2009 |
Comparison of desaturation and resaturation response times between transmission and reflectance pulse oximeters.
Topics: Adult; Androstanols; Anesthetics, Intravenous; Apnea; Breast; Equipment Design; Female; Fentanyl; Fi | 2010 |
Comments on "Propofol versus sevoflurane for fiberoptic intubation under spontaneous breathing anesthesia in patients difficult to intubate".
Topics: Airway Management; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Apnea; | 2011 |
[Noninvasive ventilation through a nasal mask to sedate a man with amyotrophic lateral sclerosis during percutaneous endoscopic gastrostomy].
Topics: Amyotrophic Lateral Sclerosis; Apnea; Deep Sedation; Endoscopy; Enteral Nutrition; Gastrostomy; Huma | 2011 |
Clinical evaluation of total intravenous anesthesia using a combination of propofol and medetomidine following anesthesia induction with medetomidine, guaifenesin and propofol for castration in Thoroughbred horses.
Topics: Anesthesia, General; Anesthetics, Intravenous; Animals; Apnea; Blood Pressure; Expectorants; Guaifen | 2011 |
A novel technique for monitoring of fast variations in brain oxygen tension using an uncoated fluorescence quenching probe (Foxy AL-300).
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Apnea; Blood Gas Analysis; Calibration; | 2011 |
Hemoglobin desaturation after propofol/remifentanil-induced apnea: a study of the recovery of spontaneous ventilation in healthy volunteers.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Apnea; Body Mass Index; Dose-Response Rela | 2012 |
Can't intubate, can't ventilate: is "rescue reversal" a pipe-dream?
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Apnea; Female; Hemoglobins; Humans; Male; Piperid | 2012 |
Abdominal relaxation during emergence from general anesthesia with propofol and remifentanil.
Topics: Abdominal Muscles; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Combined; Anest | 2013 |
General anesthesia or sedation in the intensive care unit: are we aware of the difference when we use propofol?
Topics: Anesthesia, General; Anesthetics, Intravenous; Apnea; Child; Conscious Sedation; Critical Care; Drug | 2003 |
Anesthetic management in Joubert syndrome.
Topics: Agenesis of Corpus Callosum; Anesthesia; Anesthesia, Caudal; Apnea; Ataxia; Brain; Corpus Callosum; | 2004 |
Target-controlled infusion of propofol for a patient with myotonic dystrophy.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; Apnea; Catheter Ab | 2005 |
Deep sedation with propofol in patients with Rett syndrome.
Topics: Anesthetics, Intravenous; Apnea; Case-Control Studies; Child; Conscious Sedation; Female; Humans; Pr | 2006 |
Emergency department procedural sedation and analgesia: A Canadian Community Effectiveness and Safety Study (ACCESS).
Topics: Adolescent; Adult; Age Factors; Aged; Apnea; Blood Gas Monitoring, Transcutaneous; Bradycardia; Cana | 2006 |
Does propofol and alfentanil-induced sedation cause periodic apnoea in chronic renal failure patients?
Topics: Alfentanil; Anesthetics, Combined; Anesthetics, Intravenous; Apnea; Case-Control Studies; Female; Hu | 2010 |
Doxapram in tubeless anaesthesia for microlaryngeal surgery.
Topics: Anesthesia, Intravenous; Apnea; Doxapram; Humans; Intraoperative Complications; Intubation; Intubati | 1993 |
Adverse effects of administration of propofol with various preanesthetic regimens in dogs.
Topics: Anesthesia, Inhalation; Animals; Apnea; Blood Pressure; Carbon Dioxide; Dog Diseases; Dogs; Female; | 1993 |
An alternative method of increasing PCO2 using apnoea and continuous positive airway pressure.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Apnea; Carbon Dioxide; Enflurane; Female; Humans; Hydr | 1993 |
Respiratory depression and apnea induced by propofol in dogs.
Topics: Anesthetics, Intravenous; Animals; Apnea; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Fe | 1998 |
Effect of propofol at two injection rates or thiopentone on post-intubation apnoea in the dog.
Topics: Anesthetics, Intravenous; Animals; Apnea; Dog Diseases; Dogs; Female; Incidence; Intubation, Intratr | 2001 |
A comparative study of induction and recovery characteristics of propofol and midazolam.
Topics: Adolescent; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Apnea; Blood Pressure; Femal | 2001 |
Pharmacodynamic properties of propofol during recovery from anaesthesia.
Topics: Adult; Analysis of Variance; Anesthesia Recovery Period; Anesthesia, Intravenous; Apnea; Cognition; | 1992 |
Effect of propofol in brainstem auditory evoked responses.
Topics: Apnea; Evoked Potentials, Auditory, Brain Stem; Humans; Propofol | 1992 |
Tubeless anaesthesia for microlaryngeal surgery.
Topics: Adult; Anesthesia, Intravenous; Anesthesia, Local; Apnea; Blood Pressure; Carbon Dioxide; Female; Hu | 1990 |
Preliminary studies on the use of propofol in the domestic pigeon (Columba livia).
Topics: Anesthesia; Animals; Animals, Domestic; Apnea; Bird Diseases; Columbidae; Female; Heart Rate; Inject | 1990 |
Propofol: a new intravenous anaesthetic.
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Apnea; Female; Humans; Hypotension; Middle Aged; P | 1988 |
[Respiratory effects of propofol].
Topics: Anesthetics; Apnea; Humans; Phenols; Propofol; Respiration | 1987 |
[Propofol in scheduled orthopedic surgery].
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics; Apnea; Drug Evaluation; Fem | 1987 |
Propofol ('Diprivan') by intermittent bolus with nitrous oxide in oxygen for body surface operations.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Anesthesia, Intravenous; Apnea; Dose-Response Relati | 1985 |
Assessment and modification of pain on induction with propofol (Diprivan).
Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics; Apnea; Female; Hemodynamics; Humans; Lidocaine; M | 1985 |