propofol has been researched along with Aortic Valve Stenosis in 12 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Aortic Valve Stenosis: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol is twice as likely as etomidate to evoke hypotension in anaesthesia induction of patients with severe aortic stenosis; however, etomidate transiently decreases post-operative serum cortisol concentrations." | 9.12 | Propofol causes more hypotension than etomidate in patients with severe aortic stenosis: a double-blind, randomized study comparing propofol and etomidate. ( Bendel, S; Pölönen, P; Ruokonen, E; Uusaro, A, 2007) |
| "Study elucidates and compares the mitochondrial bioenergetic-related molecular basis of sevoflurane and propofol cardioprotection during aortic valve replacement surgery due to aortic valve stenosis." | 5.16 | Mitochondrial molecular basis of sevoflurane and propofol cardioprotection in patients undergoing aortic valve replacement with cardiopulmonary bypass. ( Buzadzic, B; Cekic, O; Golic, I; Jankovic, A; Jovic, M; Korac, A; Korac, B; Micovic, S; Milojevic, P; Nenadic, D; Nezic, D; Otasevic, V; Stancic, A; Velickovic, K; Vucetic, M, 2012) |
| "Propofol is twice as likely as etomidate to evoke hypotension in anaesthesia induction of patients with severe aortic stenosis; however, etomidate transiently decreases post-operative serum cortisol concentrations." | 5.12 | Propofol causes more hypotension than etomidate in patients with severe aortic stenosis: a double-blind, randomized study comparing propofol and etomidate. ( Bendel, S; Pölönen, P; Ruokonen, E; Uusaro, A, 2007) |
| "Remifentanil was associated with a lower oxygen saturation nadir, as compared to propofol (91." | 1.72 | Propofol Versus Remifentanil Sedation for Transcatheter Aortic Valve Replacement: A Single Academic Center Experience. ( Doan, V; Kolarczyk, LM; Kumar, PA; Liu, Y; Smeltz, AM; Teeter, EG; Vavalle, JP, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 4 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Takahashi, M | 1 |
| Mouillet, G | 1 |
| Khaled, A | 1 |
| Boukantar, M | 1 |
| Gallet, R | 1 |
| Rubimbura, V | 1 |
| Lim, P | 1 |
| Dubois-Rande, JL | 1 |
| Teiger, E | 1 |
| Kronfli, AP | 1 |
| Lehman, E | 1 |
| Yamane, K | 1 |
| Roberts, SM | 1 |
| Cios, TJ | 1 |
| Neuburger, PJ | 1 |
| Rong, LQ | 1 |
| Doan, V | 1 |
| Liu, Y | 1 |
| Teeter, EG | 1 |
| Smeltz, AM | 1 |
| Vavalle, JP | 1 |
| Kumar, PA | 1 |
| Kolarczyk, LM | 1 |
| Mayr, NP | 1 |
| Wiesner, G | 1 |
| van der Starre, P | 1 |
| Hapfelmeier, A | 1 |
| Goppel, G | 1 |
| Kasel, AM | 1 |
| Hengstenberg, C | 1 |
| Husser, O | 1 |
| Schunkert, H | 1 |
| Tassani-Prell, P | 1 |
| Carrió, M | 1 |
| Carmona, P | 1 |
| Jovic, M | 1 |
| Stancic, A | 1 |
| Nenadic, D | 1 |
| Cekic, O | 1 |
| Nezic, D | 1 |
| Milojevic, P | 1 |
| Micovic, S | 1 |
| Buzadzic, B | 1 |
| Korac, A | 1 |
| Otasevic, V | 1 |
| Jankovic, A | 1 |
| Vucetic, M | 1 |
| Velickovic, K | 1 |
| Golic, I | 1 |
| Korac, B | 1 |
| Ho, AM | 1 |
| Karmakar, MK | 1 |
| Cromheecke, S | 1 |
| Pepermans, V | 1 |
| Hendrickx, E | 1 |
| Lorsomradee, S | 1 |
| Ten Broecke, PW | 1 |
| Stockman, BA | 1 |
| Rodrigus, IE | 1 |
| De Hert, SG | 1 |
| Filipovic, M | 1 |
| Michaux, I | 1 |
| Wang, J | 1 |
| Hunziker, P | 1 |
| Skarvan, K | 1 |
| Seeberger, M | 1 |
| Bendel, S | 1 |
| Ruokonen, E | 1 |
| Pölönen, P | 1 |
| Uusaro, A | 1 |
| Pedersen, CM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Anesthesia for Catheter Aortic Valve ImplantATIOn Registry[NCT01390675] | 10,000 participants (Anticipated) | Observational | 2011-06-30 | Recruiting | |||
| A Prospective, Randomized, Blinded, Controlled Study Evaluating the Efficacy of Continuous Lumbar Plexus Block With and Without Parasacral Block in Patients Undergoing Total Hip Replacement[NCT02161484] | 10 participants (Actual) | Interventional | 2014-01-31 | Terminated (stopped due to The computer is crushed and all data is lost (IT was not able to recover it. Last data was collected 6.17.14)) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Complications such as drug toxicity, arrhythmia, bradycardia, hematoma, Foot Drop, allergic reaction will be recorded" (NCT02161484)
Timeframe: 48 hours after the start of the surgery
| Intervention | Number of complications (Number) |
|---|---|
| Continuous Lumbar Plexus Block With Parasacral Nerve Block | 0 |
| Lumbar Plexus Nerve Block | 0 |
Postoperative pain assessments using a 11-point numerical rating during physical therapy and at rest. This pain scale ranges from 0, being no pain at all, up to 10 being the worst pain ever experience. (NCT02161484)
Timeframe: 24 hours after the start of surgery
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Pain at Rest | Pain with Movement | |
| Continuous Lumbar Plexus Block With Parasacral Nerve Block | 4.25 | 7.25 |
| Lumbar Plexus Nerve Block | 2.2 | 4.4 |
Postoperative pain assessments using a 11-point numerical rating during physical therapy and at rest. This pain scale ranges from 0, being no pain at all, up to 10 being the worst pain ever experience. (NCT02161484)
Timeframe: 48 hours after the start of surgery
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Pain at Rest | Pain with Movement | |
| Continuous Lumbar Plexus Block With Parasacral Nerve Block | 1 | 8 |
| Lumbar Plexus Nerve Block | 2 | 5 |
Postoperative pain assessments using a 11-point numerical rating during physical therapy and at rest. This pain scale ranges from 0, being no pain at all, up to 10 being the worst pain ever experience. (NCT02161484)
Timeframe: 6 hours after the start of surgery
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Pain at Rest | Pain with Movement | |
| Continuous Lumbar Plexus Block With Parasacral Nerve Block | 2.6 | 3.5 |
| Lumbar Plexus Nerve Block | 3.6 | 5 |
4 trials available for propofol and Aortic Valve Stenosis
| Article | Year |
|---|---|
Mitochondrial molecular basis of sevoflurane and propofol cardioprotection in patients undergoing aortic valve replacement with cardiopulmonary bypass.
Topics: Aged; Anesthetics; Aortic Valve; Aortic Valve Stenosis; ATP Synthetase Complexes; Cardiopulmonary By | 2012 |
Cardioprotective properties of sevoflurane in patients undergoing aortic valve replacement with cardiopulmonary bypass.
Topics: Aged; Anesthetics, Inhalation; Aortic Valve; Aortic Valve Stenosis; Cardiopulmonary Bypass; Female; | 2006 |
Effects of sevoflurane and propofol on left ventricular diastolic function in patients with pre-existing diastolic dysfunction.
Topics: Adult; Aged; Anesthetics, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Aortic Valve S | 2007 |
Propofol causes more hypotension than etomidate in patients with severe aortic stenosis: a double-blind, randomized study comparing propofol and etomidate.
Topics: Aged; Analysis of Variance; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2007 |
8 other studies available for propofol and Aortic Valve Stenosis
| Article | Year |
|---|---|
Perioperative Outcomes of Adjunctive Hypnotherapy Compared with Conscious Sedation Alone for Patients Undergoing Transfemoral Transcatheter Aortic Valve Implantation.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Aortic Valve Stenosis; Conscious Sedation; Female; Human | 2020 |
Dexmedetomidine Is an Equal Cost Alternative to Propofol in Transcatheter Aortic Valve Replacement, With Equivalent In-Hospital and 30-Day Outcomes.
Topics: Aortic Valve; Aortic Valve Stenosis; Dexmedetomidine; Hospital Mortality; Hospitals; Humans; Propofo | 2021 |
The Economics of Transcatheter Aortic Valve Replacement and the Anesthesiologist.
Topics: Anesthesiologists; Aortic Valve; Aortic Valve Stenosis; Dexmedetomidine; Hospitals; Humans; Propofol | 2021 |
Propofol Versus Remifentanil Sedation for Transcatheter Aortic Valve Replacement: A Single Academic Center Experience.
Topics: Aortic Valve; Aortic Valve Stenosis; Conscious Sedation; Humans; Oxygen Saturation; Propofol; Remife | 2022 |
Dexmedetomidine versus propofol-opioid for sedation in transcatheter aortic valve implantation patients: a retrospective analysis of periprocedural gas exchange and hemodynamic support.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, General; Aortic Valve Stenosis; Carbon Diox | 2018 |
[Ventricular fibrillation and cardiorespiratory arrest during dexmedetomidine administration].
Topics: Adrenergic alpha-2 Receptor Agonists; Advanced Cardiac Life Support; Aged; Airway Extubation; Aortic | 2015 |
Combined paravertebral lumbar plexus and parasacral sciatic nerve block for reduction of hip fracture in a patient with severe aortic stenosis.
Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Intravenous; Aortic Valve Stenosis; Dement | 2002 |
The effect of sedation with propofol on postoperative bronchoconstriction in patients with hyperreactive airway disease.
Topics: Aged; Aortic Valve Stenosis; Asthma; Bronchial Spasm; Humans; Lung Volume Measurements; Male; Postop | 1992 |