Page last updated: 2024-11-03

propofol and Anesthesia Awareness

propofol has been researched along with Anesthesia Awareness in 24 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"4 μg/(kg×h) as an adjuvant of sevoflurane inhalational anesthesia, could improve the wake-up test quality, and maintain hemodynamic stability during scoliosis surgery."9.22[Impact of dexmedetomidine-sevoflurane anesthesia on intraoperative wake-up test in children patients undergoing scoliosis surgery]. ( An, HX; Quan, LX; Wang, DX, 2016)
"4 μg/(kg×h) as an adjuvant of sevoflurane inhalational anesthesia, could improve the wake-up test quality, and maintain hemodynamic stability during scoliosis surgery."5.22[Impact of dexmedetomidine-sevoflurane anesthesia on intraoperative wake-up test in children patients undergoing scoliosis surgery]. ( An, HX; Quan, LX; Wang, DX, 2016)
"No unintended anesthesia awareness was noted during the study period."2.80Sedation monitoring during open muscle biopsy in children by Comfort Score and Bispectral Index - a prospective analysis. ( Dohna-Schwake, C; Felderhoff-Müser, U; Müller, O; Schara, U; Tschiedel, E, 2015)
" No significant difference was noted in the dosage of propofol used between the BIS and control groups (168."2.79Prospective randomized trial of bispectral index monitoring of sedation depth during flexible bronchoscopy. ( Carmi, U; Fruchter, O; Kramer, MR; Rosengarten, D; Tirosh, M, 2014)
" The dose-response relationship of propofol for the maintenance of adequate anesthesia based on BIS, movement and hemodynamic response was investigated using a fixed effect-site concentration of sufentanil (0."2.76Predicted effect-site concentration of propofol and sufentanil for gynecological laparoscopic surgery. ( Cho, CK; Jeong, SJ; Jung, SM; Kang, PS; Kwon, HU; Lim, YS; Oh, JY; Yang, CW, 2011)
"Intraoperative awareness and postoperative nausea/vomiting were assessed at follow-up."1.46Total intravenous anesthesia produces outcomes superior to those with combined intravenous-inhalation anesthesia for laparoscopic gynecological surgery at high altitude. ( Li, H; Peng, Q; Xu, R; Xu, S; Yang, J; Zhang, G; Zhang, Q; Zhou, S, 2017)
"Propofol TIVA was performed following the Servin formula, while sevoflurane was administered based on the age of the patients."1.43A comparison of BIS recordings during propofol-based total intravenous anaesthesia and sevoflurane-based inhalational anaesthesia in obese patients. ( Gaszyński, T; Wieczorek, A, 2016)
"45."1.40Monitoring hypnotic effect and nociception with two EEG-derived indices, qCON and qNOX, during general anaesthesia. ( Agustí, M; Anglada, T; Gambus, P; Jensen, EW; Jospin, M; López, A; Pineda, P; Ramos, Y; Serra, R; Valencia, JF, 2014)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's22 (91.67)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Umaba, C1
Mineharu, Y1
Liang, N1
Mizota, T1
Yamawaki, R1
Ueda, M1
Yamao, Y1
Nankaku, M1
Miyamoto, S1
Matsuda, S1
Inadomi, H1
Arakawa, Y1
Rimbert, S1
Schmartz, D1
Bougrain, L1
Meistelman, C1
Baumann, C1
Guerci, P1
Park, HS1
Kim, YS1
Kim, SH1
Jeon, AR1
Kim, SE1
Choi, WJ1
Yu, H1
Wu, D1
Radek, L1
Kallionpää, RE1
Karvonen, M1
Scheinin, A1
Maksimow, A1
Långsjö, J1
Kaisti, K1
Vahlberg, T1
Revonsuo, A1
Scheinin, H1
Valli, K1
Niu, K1
Guo, C1
Han, C1
Teng, S1
Sury, M1
Rucklidge, M1
Fruchter, O1
Tirosh, M1
Carmi, U1
Rosengarten, D1
Kramer, MR1
Jensen, EW1
Valencia, JF1
López, A1
Anglada, T1
Agustí, M1
Ramos, Y1
Serra, R1
Jospin, M1
Pineda, P1
Gambus, P1
Tschiedel, E1
Müller, O1
Schara, U1
Felderhoff-Müser, U1
Dohna-Schwake, C1
Liu, J1
Zhou, Y1
Chen, S1
Xu, T1
Chen, X1
Xie, F1
Chhabra, A1
Subramaniam, R1
Srivastava, A1
Prabhakar, H1
Kalaivani, M1
Paranjape, S1
Kabukcu, HK1
Sahin, N1
Ozkaloglu, K1
Golbasi, I1
Titiz, TA1
Tewari, S1
Bhadoria, P1
Wadhawan, S1
Prasad, S1
Kohli, A1
Quan, LX1
An, HX1
Wang, DX1
Gaszyński, T1
Wieczorek, A1
Xu, R1
Zhou, S1
Yang, J1
Li, H1
Zhang, Q1
Zhang, G1
Xu, S1
Peng, Q1
Kunisawa, T1
Ueno, M1
Suzuki, A1
Takahata, O1
Iwasaki, H1
Gonano, C1
Meitner, E1
Kettner, SC1
Chiari, A1
Marhofer, P1
Jung, SM1
Yang, CW1
Oh, JY1
Cho, CK1
Kang, PS1
Lim, YS1
Jeong, SJ1
Kwon, HU1
An, J1
Fang, Q1
Huang, C1
Qian, X1
Fan, T1
Lin, Y1
Guo, Q1
Linstedt, U1
Haecker, KG1
Prengel, AW1
Reboso, JA1
Méndez, JA1
Reboso, HJ1
León, AM1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
EEG Analysis During Light Propofol Sedation[NCT03362775]Phase 130 participants (Anticipated)Interventional2018-11-01Recruiting
The Neural Mechanisms of Anesthesia and Human Consciousness (LOC-2013)[NCT01889004]Phase 447 participants (Actual)Interventional2014-02-28Completed
Compatibility of Qnox Values With Hemodynamic Changes as a Predictor of Pain Response in Tracheal Intubation Procedures[NCT04215289]54 participants (Actual)Observational2019-11-26Completed
Comparison Between Manual Versus Closed-loop Titration of Propofol and Remifentanil Guided by the qCon and qNox Indexes During Induction and Maintenance of General Anesthesia in Adult Patients: a Multicentre Randomized Controlled Study[NCT03540875]62 participants (Actual)Interventional2018-07-02Terminated (stopped due to Modification of the device)
[NCT01695486]30 participants (Actual)Observational2011-10-31Completed
EEG-based Depth of Anesthesia-monitoring During General Anesthesia - Effects on Time to Wake-up and Post-operative Cognition[NCT04529304]100 participants (Anticipated)Interventional2021-01-08Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for propofol and Anesthesia Awareness

ArticleYear
Spectral entropy monitoring for adults and children undergoing general anaesthesia.
    The Cochrane database of systematic reviews, 2016, Mar-14, Volume: 3

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Anesthetics; Child; Entropy; Humans; Intraop

2016

Trials

9 trials available for propofol and Anesthesia Awareness

ArticleYear
MOTANA: study protocol to investigate motor cerebral activity during a propofol sedation.
    Trials, 2019, Aug-28, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Anesthetics, Intravenous; Cortical Synchronization; Electroencephalography; Franc

2019
Prospective randomized trial of bispectral index monitoring of sedation depth during flexible bronchoscopy.
    Respiration; international review of thoracic diseases, 2014, Volume: 87, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Bronchoscopy; Conscious Sedation; Consciousness Monitors; Female; Hu

2014
Sedation monitoring during open muscle biopsy in children by Comfort Score and Bispectral Index - a prospective analysis.
    Paediatric anaesthesia, 2015, Volume: 25, Issue:3

    Topics: Adolescent; Analgesia; Anesthetics, Intravenous; Area Under Curve; Biopsy; Child; Child, Preschool;

2015
Entropy vs standard clinical monitoring using total intravenous anesthesia during transvaginal oocyte retrieval in patients for in vitro fertilization.
    Journal of clinical anesthesia, 2016, Volume: 34

    Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Female; Fentanyl; Fer

2016
[Impact of dexmedetomidine-sevoflurane anesthesia on intraoperative wake-up test in children patients undergoing scoliosis surgery].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2016, 10-18, Volume: 48, Issue:5

    Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Anesthesia, General; Arterial Pressur

2016
Effect of earplugs on propofol requirement and awareness with recall during spinal anesthesia.
    Minerva anestesiologica, 2010, Volume: 76, Issue:7

    Topics: Aged; Anesthesia, Spinal; Double-Blind Method; Ear Protective Devices; Female; Humans; Hypnotics and

2010
Predicted effect-site concentration of propofol and sufentanil for gynecological laparoscopic surgery.
    Acta anaesthesiologica Scandinavica, 2011, Volume: 55, Issue:1

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Pressure; Consciousness

2011
Deeper total intravenous anesthesia reduced the incidence of early postoperative cognitive dysfunction after microvascular decompression for facial spasm.
    Journal of neurosurgical anesthesiology, 2011, Volume: 23, Issue:1

    Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Cognition Disorders; Consciousness M

2011
Light levels of anaesthesia after relaxation for tracheal intubation - comparison of succinylcholine and cis-atracurium.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:6

    Topics: Adult; Anesthesia; Anesthetics, Intravenous; Atracurium; Double-Blind Method; Electroencephalography

2012

Other Studies

14 other studies available for propofol and Anesthesia Awareness

ArticleYear
Intraoperative hand strength as an indicator of consciousness during awake craniotomy: a prospective, observational study.
    Scientific reports, 2022, 01-07, Volume: 12, Issue:1

    Topics: Adult; Aged; Anesthetics, Intravenous; Brain Diseases; Consciousness; Craniotomy; Female; Hand; Hand

2022
Comparison of electroencephalogram between propofol- and thiopental-induced anesthesia for awareness risk in pregnant women.
    Scientific reports, 2020, 04-10, Volume: 10, Issue:1

    Topics: Adult; Anesthesia, Obstetrical; Beta Rhythm; Cesarean Section; Delta Rhythm; Female; Humans; Intraop

2020
Effects of different methods of general anesthesia on intraoperative awareness in surgical patients.
    Medicine, 2017, Volume: 96, Issue:42

    Topics: Adult; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation

2017
Dreaming and awareness during dexmedetomidine- and propofol-induced unresponsiveness.
    British journal of anaesthesia, 2018, Volume: 121, Issue:1

    Topics: Acoustic Stimulation; Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Arousal; Conscious S

2018
Equipment failure of intravenous syringe pump detected by increase in Narcotrend stage: A case report.
    Medicine, 2018, Volume: 97, Issue:47

    Topics: Adolescent; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Electroencep

2018
Sedation of children--perspectives across hospital specialties.
    SAAD digest, 2013, Volume: 29

    Topics: Adolescent; Anesthesiology; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intrave

2013
Up-to-date or out-of-date: does thiopental have a future in obstetric general anaesthesia?
    International journal of obstetric anesthesia, 2013, Volume: 22, Issue:3

    Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Intravenous; Drug Compounding; Fem

2013
Monitoring hypnotic effect and nociception with two EEG-derived indices, qCON and qNOX, during general anaesthesia.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:8

    Topics: Ambulatory Surgical Procedures; Analgesics; Anesthesia, General; Anesthetics, General; Consciousness

2014
Monitoring hypnotic effect and nociception with two EEG-derived indices, qCON and qNOX, during general anaesthesia.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:8

    Topics: Ambulatory Surgical Procedures; Analgesics; Anesthesia, General; Anesthetics, General; Consciousness

2014
Monitoring hypnotic effect and nociception with two EEG-derived indices, qCON and qNOX, during general anaesthesia.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:8

    Topics: Ambulatory Surgical Procedures; Analgesics; Anesthesia, General; Anesthetics, General; Consciousness

2014
Monitoring hypnotic effect and nociception with two EEG-derived indices, qCON and qNOX, during general anaesthesia.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:8

    Topics: Ambulatory Surgical Procedures; Analgesics; Anesthesia, General; Anesthetics, General; Consciousness

2014
[Study on the Evaluation Index of Depth of Anesthesia Awareness Based on Sample Entropy and Decision Tree].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2015, Volume: 32, Issue:2

    Topics: Algorithms; Anesthesia, General; Decision Trees; Electroencephalography; Entropy; Humans; Intraopera

2015
Bispectral Index Monitoring in Patients Undergoing Open Heart Surgery.
    Brazilian journal of cardiovascular surgery, 2016, Volume: 31, Issue:2

    Topics: Aged; Anesthetics, Intravenous; Consciousness Monitors; Coronary Artery Bypass; Fentanyl; Hemodynami

2016
A comparison of BIS recordings during propofol-based total intravenous anaesthesia and sevoflurane-based inhalational anaesthesia in obese patients.
    Anaesthesiology intensive therapy, 2016, Volume: 48, Issue:4

    Topics: Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthe

2016
Total intravenous anesthesia produces outcomes superior to those with combined intravenous-inhalation anesthesia for laparoscopic gynecological surgery at high altitude.
    The Journal of international medical research, 2017, Volume: 45, Issue:1

    Topics: Adolescent; Adult; Altitude; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Inhal

2017
Bispectral index monitor prevented intraoperative awareness during partial cardiopulmonary bypass.
    Journal of cardiothoracic and vascular anesthesia, 2010, Volume: 24, Issue:4

    Topics: Cardiopulmonary Bypass; Consciousness Monitors; Humans; Intraoperative Awareness; Male; Middle Aged;

2010
Design and implementation of a closed-loop control system for infusion of propofol guided by bispectral index (BIS).
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:8

    Topics: Abdomen; Algorithms; Anesthesia, Intravenous; Anesthetics, Intravenous; Clinical Alarms; Computer Si

2012